Clinical trials: Functional Movement Disorder, open to volunteers
Long QT Syndrome, Channelopathies
Physical Activity and Functional Capacity in Patients With Congenital Long QT Syndrome
Patients with congenital long QT syndrome (LQTS) have traditionally been discouraged from physical activity and competitive sports, although the rate of exercise-related arrhythmic events is considered low.
- Trial name
- CANMOVE (NCT07862491)
- Testing
- Questionnaires, Cardiopulmonary exercise testing, 24-hour Holter monitoring
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo
Parkinson Disease (PD)
Effects of Dual-Task Training on Upper Extremity Function in Parkinson's Disease
The goal of this clinical trial is to investigate the effects of dual-task training on upper extremity function and muscle thickness in individuals with Parkinson's disease.
- Trial name
- NCT07536542
- Testing
- Dual-Task Training
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Ankara University
Parkinson's Disease
Study to Assess Real Life Effectiveness of Foslevodopa/Foscarbidopa in Adult German Participants at Initial Stages of Advanced Parkinson's Disease (EARLY-FOS)
Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot from person to person.
- Trial name
- NCT06916507
- Where
- 19 sites in Germany
- Volunteers
- 125 people
- Sponsor
- AbbVie
Parkinson Disease
Deep Brain Stimulation in Parkinson's Disease: Motor and Functional Outcomes
Introduction: Parkinson's Disease (PD) is a progressive neurodegenerative condition characterized by classic motor symptoms, such as bradykinesia, rigidity, resting tremor, and postural instability, which directly compromise the…
- Trial name
- NCT07567599
- Testing
- Deep Brain Stimulation
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of Minas Gerais
PARKINSON DISEASE (Disorder)
Whole-Body Photobiomodulation for Motor and Cognitive Changes in Parkinson's Disease
This study aims to exploratorily evaluate the extent of motor and cognitive changes, as well as the safety, resulting from approximately 10 weeks of whole-body photobiomodulation (PBM) therapy (about three sessions per week, once…
- Trial name
- PBM (NCT07271927)
- Testing
- Photobiomodulation
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Pusan National University Yangsan Hospital
Parkinson's Disease
Action Observation and Motor Imagery Therapy in Parkinson's Disease
In recent years, motor imagery (MI) and action observation (AO) therapy strategies have been used in rehabilitation programs to increase motor learning in Parkinson's disease (PD).
- Trial name
- NCT06154356
- Testing
- Action observation and motor imagery therapy for rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Karamanoğlu Mehmetbey University
Parkinson Disease
Function-based Accelerated Stimulation Therapy (FAST-therapy) for Freezing of Gait (FOG) After Parkinson's Disease (PD)
Parkinson disease (PD) is a common disorder in which reduced speed of movement results from inadequate brain production of the chemical dopamine.
- Trial name
- NCT05509842
- Testing
- rTMS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Parkinson Disease
Comparison of Vestibular and Dual-Task Rehabilitation in Parkinson's Disease
Parkinson's disease (PD) is a long-term condition that affects movement, balance, and thinking abilities. It can cause tremor, stiffness, slow movements, and difficulty maintaining balance.
- Trial name
- NCT07277205
- Testing
- Vestibular Rehabilitation, Cognitive-Motor Dual Task Activities
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Marmara University
Spinal Cord Injuries, Spinal Cord Injury Cervical
Restoring Motor and Sensory Hand Function in Tetraplegia Using a Neural Bypass System
This is a single-cohort early feasibility trial to determine whether an investigational device called the Bidirectional Neural Bypass System can lead to the restoration of movement and sensation in the hand and wrist of up to…
- Trial name
- NCT03680872
- Testing
- Bidirectional Neural Bypass System
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Chad Bouton
Stroke
Impact of Mirror Therapy Combined With Conventional Training on Gait and Lower Limb Motor Function Among Post-Stroke Patients
This randomized controlled trial aims to evaluate the effects of mirror therapy combined with conventional training on gait and lower limb motor function among post-stroke patients.
- Trial name
- NCT07797712
- Testing
- Mirror Therapy Based Functional Training, Conventional Lower Limb Training
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Ibadat International University, Islamabad
Kinesiophobia (Fear of Movement), Rhematoid Arthritis
Kinesiophobia in Rheumatoid Arthritis: Associations With Functional Disability, Disease Activity, and Related Clinical Factors
Objectives: Impairment of physical function is a core feature of RA, particularly in patients with high disease activity where pain and inflammation directly limit movement.
- Conditions
- Kinesiophobia (Fear of Movement), Rhematoid Arthritis, Rheumatoid Arthritis (RA), Rheumatoid
- Trial name
- NCT07435272
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Minia University
Functional Neurological Disorder, Motor Symptoms
Investigating the Neurophysiology of the Motor System and the Feasibility of Vagus Nerve Stimulation in Functional Neurological Disorder (FND)
This clinical study will test if adding a non-invasive stimulation of the vagus nerve through the ear during physiotherapy brings an improvement to FND (Functional Neurological Disorder) patients with motor symptoms.
- Trial name
- TMS-VNS (NCT07710677)
- Testing
- Vagial Nerve Stimulation (VNS) active stimulation
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
PARKINSON DISEASE (Disorder)
Effect of Hand Rehabilitation on Cognitive Function in Patients With PD
Evidence suggests the association between fine motor skills of the hand and cognitive function, as well as the positive effects of hand rehabilitation on hand function and the effectiveness of cognitive rehabilitation on…
- Trial name
- NCT07702929
- Testing
- Hand Sensorimotor Rehabilitation, Cognitive Remediation
- Volunteers
- 48 people
- Sponsor
- Isfahan University of Medical Sciences
Functional Neurological Disorder, Motor FND
Impact of Theta Burst Repetitive Transcranial Magnetic Stimulation on the Patient's Self-reported Improvement in Their Motor Functional Neurological Disorder
Functional neurological disorder (FND) is a condition that causes significant suffering and disability. It is defined by the presence of neurological symptoms that interfere with an individual's functioning and are not consistent…
- Trial name
- Thêta-mTNF (NCT07527403)
- Testing
- theta-burst rTMS (repetitive transcranial magnetic stimulation)
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Hospital Center Guillaume Régnier
Neuromuscular Diseases
Controlled Study of Upper and Lower Limb Movements in Patients Patients with Pathologies That Have an Impact on Ambulation or Motor Function
The main aim of the study is to validate the algorithms developed to analyze the signals from the various sensors contained in the magneto-inertial control units and reconstruct upper and lower limb movements under different…
- Trial name
- NCT06439823
- Testing
- ActiMyo®/Syde®
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Laurent Servais
Parkinsons Disease (PD)
Transcranial Direct Current Stimulation for Motor Function and Fatigue in PD
The investigators hypothesize that multi-session anodal tDCS (atDCS) of the left primary motor cortex (M1) will induce long-lasting effects in improving motor function and reducing motor fatigue and fatigability in PD patients.
- Trial name
- tDCS (NCT06883266)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Sanford Health
Hand Transplantation, Peripheral Nerve Injuries
Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair
This study adopts a strategy that has arisen from basic neuroscience research on facilitating adaptive brain plasticity and applies this to rehabilitation to improve functional recovery in peripheral nervous system injuries…
- Conditions
- Hand Transplantation, Peripheral Nerve Injuries, Neurologic Rehabilitation
- Trial name
- NCT03610763
- Testing
- Transcranial Direct Current Stimulation, Modified Constraint Induced Movement Therapy
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of Missouri-Columbia
Subacromial Impingement Syndrome
Effects of Myofascial Chain Tension Modulation Combined With Scapular Corrective Exercise on Scapular Movement Performance and Functional Outcomes in Tennis Players With Subacromial Impingement Syndrome
Subacromial Impingement Syndrome (SIS) is characterized by abnormal scapular motion, including decreased upward rotation, increased internal rotation, and excessive anterior tilting, which impair shoulder and arm function.
- Trial name
- NCT07385378
- Testing
- Instrument-Assisted Soft Tissue Mobilization, Elastic band
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Urinary Bladder Sphincter Disorder
Study of Bladder-sphincter Symptoms in Functional Neurological Disorders
A significant proportion of patients with functional neurological disorders (FND) report urinary, anorectal or genitosexual disorders. However, until now, no study has focused on bladder-sphincter disorders in patients with FND.
- Trial name
- URO-TNF (NCT05689866)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Virtual Reality, Kinesiophobia
Can Virtual Reality Exercise Help Restore Both Body and Mind in Chronic Low Back Pain
The goal of this clinical trial is to learn if an immersive virtual reality (VR) exercise program can help reduce back pain and improve physical function and psychological well-being in adults with chronic low back pain.
- Conditions
- Virtual Reality, Kinesiophobia, Chronic Low Back Pain (CLBP), Central Sensitization
- Trial name
- NCT07207083
- Testing
- Immersive Virtual Reality-based Exercise (FitXR, Meta Quest 3s), Conventional Exercise Program (Matched Exercise, without VR)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- dongmin kang