Clinical trials: Functional Outcomes
Type 2 Diabetes Mellitus 1
AI-Driven MRF Type 2 Diabetes Integrating DHT IF and Resistance Training to OM and Functional Outcomes
This randomized controlled trial aims to evaluate the effectiveness of an AI-driven multimodal rehabilitation framework combining digital health technologies, intermittent fasting, and resistance training in individuals with Type…
- Trial name
- NCT07336459
- Testing
- AI-Guided Multimodal Rehabilitation Program, Standard Diabetes Care
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Superior University
Stroke
Long Term Effects of Action Observation Therapy and Mirror Therapy on Upper Limb Functions
There will be a long term effects of action observation therapy and mirror therapy on upper limb functional outcomes after subacute stroke.
- Trial name
- NCT06027125
- Testing
- Action observation Therapy, Mirror Therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Cannabis, Cannabis Use
Impact of Reduced Cannabis Use on Functional Outcomes (R33 Phase)
Nearly 20 million Americans report use of cannabis in the past month, and heavy cannabis use has increased by nearly 60% in the U.S. since 2007.
- Trial name
- FOCUS (NCT04567238)
- Testing
- Mobile contingency management
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Dehydration, Ischemic Stroke
BUN/Cr-based Hydration Therapy to Improve Outcome of Patients With Acute Ischemic Stroke
English Synopsis I. Title of Study: A trial of BUN/Cr-based hydration therapy to reduce stroke-in-evolution and improve short-term functional outcomes for dehydrated patients with acute ischemic stroke-version 2. II.
- Trial name
- NCT05121389
- Testing
- normal saline
- Where
- Taiwan
- Volunteers
- 288 people
- Sponsor
- Chang Gung Memorial Hospital
Secondary Dystonia
Neuroablation Versus Neuromodulation Techniques for Treatment of Secondary Dystonia
The disability inflected by dystonia encouraged the development of many neurosurgical procedures. This is a prospective study included 120 patients suffering from intractable secondary dystonia.
- Trial name
- NCT03347240
- Testing
- Brain Lesioning, Combined anterior and posterior lumbosacral rhizotomy, Deep brain stimulation
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Prostate Cancer
Evaluating the Effects of Frozen Section Technology on Oncological and Functional Outcomes at Radical Prostatectomy.
In summary this trial will test whether this new surgical technique can be used to make surgery safer and more effective whilst allowing improved quality of life for patients having surgery for prostate cancer.
- Trial name
- NeuroSAFEPROOF (NCT03317990)
- Testing
- NeuroSAFE procedure, Standard RARP
- Where
- 5 sites in United Kingdom
- Volunteers
- 407 people
- Sponsor
- University College, London
Obesity, Liver Function
Obesity and Liver Function in Oesophageal Cancer
There is an established link between sarcopenia and outcomes in oesophageal cancer. There is scant reports in the literature regarding the influences of different obesity in different compartments.
- Trial name
- NCT04152044
- Testing
- Observation of different types of obesity and liver pathology in patients undergoing and oesophagectomy
- Where
- Ireland
- Volunteers
- 658 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Deceased Organ Donor, Mild Hypothermia
The Effect of Therapeutic Hypothermia on Deceased Donor Renal Graft Outcomes - a Randomized Controlled Trial From the Region 5 Donor Management Goals Workgroup
To protect kidney function during the transplantation process by inducing mild hypothermia in the deceased organ donor before organs are recovered
- Conditions
- Deceased Organ Donor, Mild Hypothermia, Renal Function
- Trial name
- NCT01680744
- Testing
- Hypothermia
- Where
- United States
- Volunteers
- 370 people
- Sponsor
- University of California, San Francisco
Acute Urinary Retention, Benign Prostate Hypertrophy(BPH)
Study of Teverelix DP on Prostate Volume, Urinary Function and Clinical Outcomes Following Acute Urinary Retention
This randomized, double-blind, placebo-controlled Phase 2 study is evaluating Teverelix DP in men following a first episode of acute urinary retention (AUR) associated with benign prostatic hyperplasia (BPH), a population at risk…
- Trial name
- NCT07733934
- Testing
- Teverelix DP
- Volunteers
- 126 people
- Sponsor
- Antev Ltd.
Cerebral Palsy (CP)
Association Between Extremity Muscle Strength and Functional Outcomes in Children With Cerebral Palsy
The aim of this study was to evaluate whether upper and lower extremity muscle strength is a factor in activity, participation and quality of life parameters in school-age children with CP and to reveal the difference in upper…
- Trial name
- NCT07448207
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Neurologic Disorder, ALS
Functional Outcomes and Control Using Synchron BCI - Canada
Functional Outcomes and Control Using Synchron BCI - Canada (FOCUS-CAN)
- Conditions
- Neurologic Disorder, ALS, Motor Neuron Disease
- Trial name
- FOCUS-CAN (NCT07446114)
- Testing
- Stentrode
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- Synchron, Inc.
Schizophrenia, Insight Impaired
The Effects of Bimodal tDCS on Illness Severity, Insight, Functional Outcomes, Neurocognition and HRV in Schizophrenia
The study aimed to investigate the effects of bimodal anodal transcranial direct current stimulation (tDCS) over bilateral dorsolateral prefrontal cortex (DLPFC) on psychopathological symptoms, insight, psychosocial functioning…
- Conditions
- Schizophrenia, Insight Impaired, Psychotic Symptoms, Schizoaffective Disorder
- Trial name
- NCT03701100
- Testing
- tDCS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Comparative Effectiveness Research
Comparative Functional Vision Outcomes: DAILIES TOTAL1 Toric vs. Spherical Lenses in Asian Astigmatic Patients
The goal of this comparative clinical trial is to assess the effectiveness of DAILIES TOTAL1 Toric Contact Lenses compared to Spherical Equivalent Contact Lenses in improving the functional vision of astigmatic patients, with a…
- Trial name
- NCT06230263
- Testing
- Visual acuity test
- Where
- Hong Kong
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mopsy Research
Depression
Attachment Style and Reflective Functioning in CBASP
Cognitive behavioural analysis system of psychotherapy (CBASP) is one of the only psychological models and treatments that has been designed specifically for patients diagnosed with chronic depression.
- Trial name
- NCT02748187
- Testing
- CBASP
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Physical Activity
Clinical and Functional Outcomes at 2 Years of 4-strand Versus 5-strand Hamstring Autograft in Anterior Cruciate Ligament Reconstruction
This study aims to study differences in clinical and functional outcomes at 2 years based on hamstring graft size after single bundle anatomic ACL reconstruction using either 4-strand or 5-strand hamstring grafts.
- Trial name
- NCT03171532
- Testing
- Strands of Hamstring Autograft in ACL reconstruction
- Where
- Singapore
- Volunteers
- 80 people
- Sponsor
- National University Hospital, Singapore
Pain, Shoulder, Adhesion; Shoulder
Effects of IASTM in the Treatment of Adhesive Capsulitis
This study aimed to determine the effects of IASTM in combination with exercise in frozen shoulder. Thirty-five patients with phase II frozen shoulder included in this single-blind, randomized study.
- Conditions
- Pain, Shoulder, Adhesion; Shoulder, Myofacial Pain
- Trial name
- NCT05358730
- Testing
- Standard Exercise, Instrument Assisted Soft Tissue Mobilization (IASTM), Home Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul University - Cerrahpasa
Surgery
Brain Function Monitoring During Surgery
The purpose of this research is to gather information on the effectiveness of the Sedline Brain Function Monitor, and its use in this study to determine whether monitoring the brain activity during anesthesia will improve…
- Trial name
- NCT06619730
- Testing
- Sedline Brain Function Monitor
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Stroke, Weakness of Extremities as Sequela of Stroke
Effects of Exoskeleton-Assisted Gait Training on Functional Rehabilitation Outcomes in Patients With Stroke
The goal of this study is to determine the efficacy of electromechanical exoskeleton-assisted gait training on rehabilitation functional outcomes in patients with stroke undergoing therapy in an in-patient rehabilitation facility.
- Trial name
- NCT03980457
- Testing
- Indego Exoskeleton, Standard Rehabilitation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Oklahoma
Constipation - Functional
PHGG-LGG Synbiotic in Pediatric Functional Constipation
This prospective, randomized controlled open-label trial evaluated the efficacy of a synbiotic consisting of partially hydrolyzed guar gum (PHGG) and Lacticaseibacillus rhamnosus GG (LGG) on clinical outcomes and gut microbiota…
- Trial name
- PHGG-LGG-FC (NCT07580729)
- Testing
- 4.3 g partially hydrolyzed guar gum 1×10⁹ CFU Lacticaseibacillus rhamnosus GG, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Eskisehir Osmangazi University
Cardiac Arrhythmia
The Objective of This Multicentre Study is to Collect Operative Data on the Related Clinical Functional Outcomes and Complications and of Market Approved Alcis Electrophysiology Catheters to Demonstrate Safety and Performance of These Devices in a Real-world Setting
The objective of this multicentre study is to collect operative data on the related clinical functional outcomes and complications and of market approved Alcis electrophysiology catheters to demonstrate safety and performance of…
- Trial name
- NCT05314218
- Testing
- Electrophysiology catheters and cables
- Where
- 2 sites in France
- Volunteers
- 168 people
- Sponsor
- Alcis
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