Clinical trials: Functional Outcomes, open to volunteers
Patients With Major Depressive Disorder
Cognitive Behavior Therapy Among Patients With Major Depressive Disorder-Multiple Episodes.
The main purpose of this study to teach the patients how to manage their depression, generalized Anxiety symptoms, mental health seeking attitude, motivation and attitude toward changing health, to improve the quality of life…
- Trial name
- NCT07300527
- Testing
- Cognitive Behavior Therapy, treatment as usual (TAU) (Control Group)
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Schizophrenia Patients, Psychoeducation
The Effect of Psychosocial Skills Focused Group Psychoeducation in Schizophrenia Patients
The aim of this study was to evaluate the effect of psychosocial skills-oriented group psychoeducation on functional recovery, treatment adherence and mental well-being in patients with schizophrenia.
- Conditions
- Schizophrenia Patients, Psychoeducation, Functional Status, Treatment Outcome
- Trial name
- Schizophrenia (NCT06872424)
- Testing
- psychosocial skills-oriented group psychoeducation
- Volunteers
- 34 people
- Sponsor
- Gazi University
Chronic Ankle Instability, CAI
Lower Extremity Mobility for CAI
This study will be conducted to determine the effect of addition of ankle mobility versus hip mobility exercises to traditional rehabilitation to patients with chronic ankle instability.
- Trial name
- NCT07584746
- Testing
- traditional rehabilitation for Chronic Ankle Instability, Ankle mobility exercises, Hip mobility exercises
- Volunteers
- 40 people
- Sponsor
- Cairo University
STROKE, Rehabilitation Outcome
Prospective Evaluation of Atrial Fibrillation-Related Stroke Patients in Rehabilitation Program (PEARL), an Observational Cohort Study
The goal of this observational study is to determine if rehabilitation program intensity impacts functional recovery and specific needs in adult ischemic stroke patients who require inpatient rehabilitation.
- Conditions
- STROKE, Rehabilitation Outcome, Brain Disease, Cardiovascular Disease Acute
- Trial name
- PEARL (NCT07253974)
- Testing
- Rehabilitation program based on Physiotherapy, occupational therapy and swallow and language therapy
- Where
- Spain
- Volunteers
- 213 people
- Sponsor
- Parc de Salut Mar
Chronic Migraine, Headache
Comprehensive Approach to Lifestyle Modification in Chronic Migraine
Migraine is a highly prevalent neurological disorder and one of the leading causes of disability worldwide, substantially affecting quality of life and individuals during their most productive years.
- Trial name
- CALM-Migraine (NCT07802860)
- Testing
- Comprehensive Lifestyle Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Functional Recovery, Upper Extremity Vascularized Composite Allotransplantation
Upper Extremity Vascularized Composite Allotransplantation: A Study Evaluating Safety, Functional Outcomes, and Patient-Reported Psychosocial Outcomes
The primary objective of this study is to evaluate the 5-year (60-month) allograft survival rate of upper extremity vascularized composite allotransplantation performed under the standardized CONSORT clinical protocol.
- Trial name
- NCT07810790
- Testing
- Upper Extremity Vascularized Composite Allotransplantation (VCA)
- Where
- 9 sites in United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Distal Radius Fracture, Kinesiophobia
The Investigation of Kinesiophobia in Conservative Distal Radius Fractures
This study aimed to investigate the predictability of kinesiophobia on functional outcomes in conservatively treated patients with distal radius fractures.
- Conditions
- Distal Radius Fracture, Kinesiophobia, Functional Status
- Trial name
- NCT07291505
- Testing
- Questionnaire and Physical Exam
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Pamukkale University
Thyroid Function, Preterm
Thyroxine Supplementation in Small for Gestational Age (SGA) Infants With Birth Weight <1500g and TSH 6-20 mIU/ml
The primary objective of this clinical trail is to evaluate whether early supplementation of levothyroxine (L-T4) at a dosage of 8 ug/kg/d, initiated in the second week of life, improves physical growth and neurodevelopmental…
- Conditions
- Thyroid Function, Preterm, SGA and Growth, Neurodevelopment Outcome
- Trial name
- NCT07625722
- Testing
- Levothyroxine Sodium (LT4) Tablets
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Shandong Provincial Hospital
Orthopaedic Disorders, Neck of Femur Fracture
Effects of Individualized Physical Therapy and Group Physical Therapy on Functional Outcomes in Patients With Femoral Neck Fracture in Gaza Strip
The research explores how individualized, one-on-one physical therapy programs versus group-based therapy sessions influence recovery in terms of functional mobility, pain reduction, muscle strength, balance, and overall quality…
- Trial name
- neck of femure (NCT07168070)
- Testing
- physical therapy and exercise, group physical therapy vs individualized physical therapy, Group Physical therapy
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University - Gaza
Acute Coronary Syndrome, Non ST Segment Elevation Acute Coronary Syndrome
Angio-based Final Functional Effect of PCI
Fractional flow reserve (FFR) has revolutionized the diagnosis and treatment of coronary artery disease (CAD), and more recently, post percutaneous coronary intervention (post-PCI) FFR has emerged as an independent predictor of…
- Conditions
- Acute Coronary Syndrome, Non ST Segment Elevation Acute Coronary Syndrome, Chronic Coronary Syndrome
- Trial name
- AFFE-PCI (NCT06255678)
- Testing
- Angiography-based vessel fractional flow reserve (vFFR) calculation
- Where
- Poland
- Volunteers
- 2,005 people
- Sponsor
- Medical University of Warsaw
Cardiac Surgeries
Early Cardiopulmonary Rehabilitation Bundle Functional Capacity and Outcomes of Cardiac Surgeries Patients
The goal of this quasi-experimental study is to evaluate the impact of Early. Cardiopulmonary Rehabilitation Bundle on Functional Capacity and Outcomes in Cardiac Surgeries Patients The main question is Patients receive early…
- Trial name
- NCT07724353
- Testing
- Early cardiopulmonary rehabilitation bundle
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Assiut University
Subacromial Impingement Syndrome
Effects of Myofascial Chain Tension Modulation Combined With Scapular Corrective Exercise on Scapular Movement Performance and Functional Outcomes in Tennis Players With Subacromial Impingement Syndrome
Subacromial Impingement Syndrome (SIS) is characterized by abnormal scapular motion, including decreased upward rotation, increased internal rotation, and excessive anterior tilting, which impair shoulder and arm function.
- Trial name
- NCT07385378
- Testing
- Instrument-Assisted Soft Tissue Mobilization, Elastic band
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Supraglottic Squamous Cell Carcinoma, Early Stage (T1-T2, N0-N1,M0)
Treatment of Early Supraglottic Squamous Cell Carcinoma With Advance Technologies
In this project, the investigators will realize an observational, prospective, multicentric and international clinical trial, to objectively compare patients with SSCC according to 3 arms of treatment: Arm 1: Radiotherapy ±…
- Trial name
- SUPRA-QoL (NCT05611515)
- Testing
- TORS
- Where
- Belgium
- Volunteers
- 108 people
- Sponsor
- Centre Hospitalier Universitaire UCLouvain Namur
Lymphoma, Malignant Solid Neoplasm
Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial
This phase III trial compares the effect of geriatric evaluation and management with survivorship health education (GEM-S) to usual care on patient-reported physical function in older survivors of cancer.
- Trial name
- GEM-S (NCT05006482)
- Testing
- Best Practice, Comprehensive Geriatric Assessment, Educational Intervention
- Where
- 45 sites in United States
- Volunteers
- 668 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Knee Osteoarthritis
ROAM OA: Functional and Patient Reported Outcomes Wearing a Knee Brace for Unicompartmental OA
The aim of this study is to conduct a comparative evaluation of the ROAM OA Single Upright Brace and the Ossur Unloader One Knee Brace in subjects with medial compartment osteoarthritis.
- Trial name
- NCT07224958
- Testing
- ROAM OA Single Upright Knee Brace, Ossur Unloader One Knee Brace or Standard of Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Rush University Medical Center
Breast Cancer, Breast Reconstruction
EndoBreast Study - Assessment of Feasibility, Functional Outcomes, and Sensitivity of the Areola-Nipple Complex in Endoscopic Mastectomy
Study Design Prospective, single-center, observational, non-interventional study conducted in routine clinical practice. No investigational treatments or modifications to standard diagnostic, therapeutic, or follow-up procedures…
- Trial name
- EndoBreast (NCT07718425)
- Testing
- endoscopic mastectomy
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Massimiliano Bortolini
Liver Transplantation, Ischaemia Reperfusion Injury
Effect of Discarding Initial Reperfusion Blood on Hemodynamics, Liver Function, and 30-Day Outcomes in Liver Transplantation
Hepatic reperfusion during liver transplantation remains a critical phase associated with significant hemodynamic and systemic disturbances, despite advances in surgical and anesthetic management.
- Conditions
- Liver Transplantation, Ischaemia Reperfusion Injury, Perioperative Complications
- Trial name
- NCT07631689
- Testing
- Reperfusion Blood Discard, Standard Liver Transplantation
- Volunteers
- 132 people
- Sponsor
- University of Sao Paulo General Hospital
Postoperative Bowel Function, Postoperative Pain
Fentanyl vs. Remifentanil in Laparoscopic Cholecystectomy: Effects on Bowel Function and Pain
Background: Postoperative ileus (POI) is a common complication after abdominal surgery, leading to delayed gastrointestinal recovery, prolonged hospitalization, and increased healthcare costs.
- Trial name
- NCT07182097
- Testing
- Fentanyl 2 µg/kg IV bolus + 1-2 µg/kg/h infusion during anesthesia, Remifentanil 1 µg/kg IV bolus + 0.1-1 µg/kg/min infusion during anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Konya City Hospital
Tuberculosis, Inflammation Biomarkers
Effects of Adjunct Omega-3 Long Chain Polyunsaturated Fatty Acids in Pulmonary Tuberculosis Patient: an Early Bactericidal Activity and Inflammatory Trial
The goal of this randomized controlled trial is to evaluate the early bactericidal activity, early inflammatory response, and safety of omega-3 long chain polyunsaturated fatty acid (n-3 PUFA) supplementation in adult patients…
- Conditions
- Tuberculosis, Inflammation Biomarkers, Liver Function Tests, Iron Status
- Trial name
- TREAT 3 (NCT07118059)
- Testing
- Omega-3 (EPA+DHA)
- Where
- South Africa
- Volunteers
- 40 people
- Sponsor
- North-West University, South Africa
Aged, Aged Subject
CREM - Clinical and Functional Outcomes in a Controlled Clinical Trial with Older Adults
To evaluate and compare the effects of different types of physical exercise on clinical and functional outcomes in the elderly. 240 community-dwelling elderly individuals of both sexes, sedentary, will be recruited for twelve…
- Trial name
- CREM (NCT06638697)
- Testing
- Free walking, Nordic walking, Dance
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul