Clinical trials: Functional Outcomes
Fracture of Femur
Outcomes of Hemiarthroplasty Versus Cephalo-medullary Fixation to Treat Unstable Intertrochanteric Femoral Fractures
Comparing functional outcomes of hemiarthroplasty (prosthetic joint) versus cephalo-medullary fixation ( proximal femoral intramedullary nail) in the treatment of unstable intertrochanteric femoral fractures (proximal femur…
- Trial name
- NCT05134805
- Testing
- Bipolar hemiarthroplasty , proximal femoral nail
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Scoliosis
Scoliosis and Functional Outcomes in Children With Juvenile Idiopathic Arthritis
Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disease that may affect musculoskeletal development and posture in children.
- Trial name
- NCT07433894
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Ulcerative Colitis
Outcomes of Transanal Tran-section and Single-stapled (TTSS) Ileal Pouch-Anal Anastomosis
This study aims to compare the functional and surgical outcomes of Ulcerative Colitis (UC) patients undergoing Transanal Transection and Singl-Stapled (TTSS) versus Double-stapled Ileal Pouch-Anal Anastomosis (IPAA)
- Trial name
- TTSS-Pouch (NCT06331637)
- Testing
- Transanal Transection and Single-Stapled anastomosis (TTSS), Double-stapled anastomosis
- Where
- Italy
- Volunteers
- 174 people
- Sponsor
- Istituto Clinico Humanitas
Sinusitis
Gold Laser Vs. Micro-Debriders for Functional Endoscopic Sinus Surgery
Sinusitis is a common medical problem, which significantly decreases patients' quality of life (QOL). Patients may have symptoms such as headaches, sinus pressure, nasal congestion and drainage, decreased sense of smell, and…
- Trial name
- NCT02900794
- Testing
- Gold Laser, Microdebridement
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Muscle Mass and Strength, Obesity & Overweight
Function and Lean Mass Preservation With Resistance Exercise During a GLP-1RA Treatment
This study aims to investigate the effect that a structured, progressive resistance exercise program may have on maintaining the muscle mass and physical function of overweight/ obese females whilst they experience a tirzepatide…
- Conditions
- Muscle Mass and Strength, Obesity & Overweight, Physical Function
- Trial name
- FLEX (NCT07457437)
- Testing
- Progressive Resistance Exercise Training Program, Habitual physical activity guidelines
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Exercise Therapy
Effects of a Metronome on Functional Outcomes in Aquatic Therapy
The purpose of this study is to determine if the use of a pacing device, a metronome, improves functional outcome measures in aquatic therapy when compared to a control group.
- Trial name
- NCT03801772
- Testing
- Metronome
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Aultman Health Foundation
Rectal Cancer
Longterm Functional Outcomes in Patients Undergoing Organ Preserving Treatment for Rectal Cancer With or Without Local Excision After Chemoradiotherapy
Treatment of rectal cancer by standard neoadjuvant chemoradiotherapy protocols leads to a complete response in about 15% of patients, or even a higher fraction if radiotherapy is followed by an Oxaliplatin based chemotherapy as…
- Trial name
- PRESERVE (NCT06249672)
- Testing
- Local excision
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Multiple Sclerosis
Costs, Quality of Life and Functional Outcomes in Veterans Treated for Multiple Sclerosis With Beta-Interferon l-B (Betaseron)
The treatment of multiple sclerosis was evolving in light of specific drug therapies to treat the disease, refinements and acceptance of imaging with MRI to diagnose and monitor the disease process, and progress in understanding…
- Trial name
- NCT00439257
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- US Department of Veterans Affairs
Achilles Tendon Rupture
Achilles Tendon Rupture Patient Outcomes at 12 Months
Achilles tendon rupture is a common injury that can significantly impact strength, function, and quality of life. While non-surgical management using structured rehabilitation protocols such as the Swansea Morriston Achilles…
- Trial name
- ATR-12 (NCT07391553)
- Testing
- Non-Surgical Management Using the SMART Protocol
- Where
- 2 sites in United Kingdom
- Volunteers
- 115 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Asthma
Lung Function Outcomes Following Removal of Airway Mucus Plugs in Patients With Asthma (FOCUS)
This is a single-center study that will evaluate the safety and tolerability of removal of mucus plugs by bronchoscopy in patients with asthma.
- Trial name
- FOCUS (NCT05748912)
- Testing
- Therapeutic bronchoscopy for removal of mucus plugs
- Where
- United States
- Sponsor
- University of California, San Francisco
Complication,Postoperative, Lung Cancer
Relationship Between Hand Dynamometer Measurements, PFT, and mFI With Postoperative Outcomes
The study will take place at SBÜ Ankara Atatürk Sanatorium Training and Research Hospital and will include 100 patients over the age of 40 who are scheduled for lung malignancy surgery after 01 April 2024.
- Trial name
- NCT06338007
- Testing
- Hand Dynamometer, Pulmonary Function Test, Modified Frailty Index
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Varicella Zoster, Varicella Meningitis
Clinical Features and Outcomes of VZV CNS Infections
The goal of this observational study is to learn about the clinical characteristics, risk factors, and long-term outcomes of varicella zoster virus (VZV)-related central nervous system (CNS) infections in adults.
- Conditions
- Varicella Zoster, Varicella Meningitis, Varicella Encephalitis, Varicella Neurological
- Trial name
- NCT07554261
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Kocaeli University
Rectal Cancer, Rectum Neoplasm
Effect of Pelvic Rehabilitation After Low Anterior Resection for Cancer Rectum. - A Randomised Controlled Trial
Study Purpose: This study aims to understand how pelvic floor rehabilitation (PFR) after low anterior resection (LAR) surgery for rectal cancer affects bowel control and quality of life compared to usual care.
- Conditions
- Rectal Cancer, Rectum Neoplasm, Rectal Neoplasms, Rectal Adenocarcinoma
- Trial name
- PERECARE (NCT06524362)
- Testing
- Pelvic Floor Physiotherapy (PFR), Conventional group
- Where
- India
- Volunteers
- 77 people
- Sponsor
- GEM Hospital & Research Center
Sarcopenia, Muscle Weakness
Functional Changes and Power Training in Older Women.
Extending quality of life and attenuating functional decline is paramount in older adults. This study investigates the effects of low-intensity power-training in older women and its effects on functional outcomes.
- Trial name
- F-POW (NCT02530723)
- Testing
- power training
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Osteoarthritis
Gait and Functional Improvement in Total Knee Arthroplasty With the Use of Verasense for Soft Tissue Balancing
The primary objectives of this study are to understand the effects of soft-tissue balancing on Gait, function and rehabilitation potential after sensor-assisted Total Knee Arthroplasty and correlate Intra-operative subjective…
- Trial name
- NCT02290119
- Testing
- Sensor-assisted TKR (Verasense), Control - Without the use of Verasense
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Orthosensor, Inc.
Remote Monitoring of Pain and Recovery Quality in the Immediate Postoperative Period Using a Digital Health Tool, Pain, Postoperative
Remote Assessment of Pain and Recovery Quality After Surgery Using a Digital Form: A Pilot Study
After surgery, doctors need to know how patients are doing, especially in the first hours after they leave the recovery room. This can be hard to track once patients go to a regular hospital room, and some symptoms - like pain or…
- Conditions
- Remote Monitoring of Pain and Recovery Quality in the Immediate Postoperative Period Using a Digital Health Tool, Pain, Postoperative, Postoperative Nausea and Vomiting, Recovery of Function (G11.427.698.620)
- Trial name
- NCT07794267
- Testing
- Digital web-based postoperative follow-up form
- Where
- Brazil
- Volunteers
- 213 people
- Sponsor
- Hospital de Base
Specific Learning Disability, Mental Health Issue
Biopsychosocial Outcomes of Mindfulness-based Instruction
Over 20% of adolescents living in the United States have a diagnosable psychiatric disorder. However, most adolescents who need mental health services do not receive them due to many reasons, including low resources in families…
- Trial name
- MindUP (NCT05787483)
- Testing
- MindUP group, active control group
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cardiovascular Complication, Complication, Postoperative
Perioperative Endothelial Dysfunction in Patients Undergoing Major Acute Abdominal Surgery
The aim of the clinical study is: 1. to examine the association between postoperative endothelial function, indirectly measured by reactive hyperemia index, and major adverse cardiovascular events including myocardial injury and…
- Trial name
- POETRYabd (NCT03010969)
- Testing
- Acute abdominal surgery
- Where
- Denmark
- Volunteers
- 224 people
- Sponsor
- Zealand University Hospital
Joint Health
A Decentralized Clinical Study Evaluating the Effectiveness of Two Different Doses of MyCondro™ on Physical Mobility and Joint Health
This study evaluates the effect of two different doses of a consumer-grade product, MyCondro™, on individuals experiencing mobility issues related to knee osteoarthritis.
- Trial name
- NCT07493239
- Testing
- MyCondro 300mg, MyCondro 600mg
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Lesaffre International
Frozen Shoulder
The Effect of Cross Training on Clinical and Functional Outcomes in Frozen Shoulder Rehabilitation
This randomized controlled, single-blind, quasi-experimental study primarily aims to investigate the effects of unilateral resistance exercise applied without directly loading the affected shoulder on muscle strength and upper…
- Trial name
- NCT07510737
- Testing
- Standard Physical Therapy Group, Cross-Education Group
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Inonu University
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