Clinical trials: Functional Outcomes
Congenital Disorders
Racial Distribution of Heterotaxy Syndrome
Heterotaxy syndrome is a heterogeneous disease that is the result of a failure of normal right-left lateralization of the abdominal and thoracic organs during development.
- Trial name
- NCT00485654
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Children's Healthcare of Atlanta
Alzheimer Disease
Frailty Outcomes And Risk With Alzheimer's Related Dementia
The primary aim of this study is to investigate the association between frailty as defined by the Fried Frailty Phenotype and risk of functional decline in patients with Alzheimer's dementia.
- Trial name
- FORWARD (NCT06570109)
- Testing
- Frailty
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Aalborg University Hospital
Knee Ligament Injury
Comparison of ACL Reconstruction With Stump Preservation and Stump Resection
To assess the clinical outcome in patients who had ACL reconstruction with preservation of the remnant and compare it with patients in whom the stump was resected
- Trial name
- NCT05364398
- Testing
- ACL reconstruction
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Rectal Cancer, Ileostomy; Functional Disturbance
Trial Evaluating the Tailored Versus the Systematic Use of Defunctioning Stoma After Total Mesorectal Excision for Rectal Cancer (GRECCAR17)
GRECCAR 17 will be the first prospective and randomized trial to assess a tailored policy in the use of defunctioning stoma after TME according to the personalized risk of anastomotic leakage.
- Trial name
- GRECCAR17 (NCT05233787)
- Testing
- Tailored use of defunctioning stoma after TME, Systematic use of defunctioning stoma
- Where
- 28 sites in France
- Volunteers
- 212 people
- Sponsor
- University Hospital, Bordeaux
ICU Acquired Weakness, Post Intensive Care Unit Syndrome
Muscle Recovery After Critical Illness
The overarching goal of the proposed study is to determine the trajectories of physical recovery and cellular markers involved with the underlying failure to recover muscle after critical illness, while exploring which…
- Conditions
- ICU Acquired Weakness, Post Intensive Care Unit Syndrome, Muscle Weakness, Critical Illness
- Trial name
- TRACER (NCT05537298)
- Where
- 3 sites in United States
- Volunteers
- 209 people
- Sponsor
- Esther Dupont-Versteegden
Prostate Cancer
Registry of Irreversible Electroporation for the Ablation of Prostate Cancer With Use of Nanoknife Device
The aim of this registry is to assess the recurrence of prostate cancer at 1 and 5 years, as well as the change in functional outcomes (e.g. incontinence or erectile function) from baseline.
- Trial name
- NCT02255890
- Where
- Netherlands
- Volunteers
- 361 people
- Sponsor
- Clinical Research Office of the Endourological Society
Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment
"Ultrasound Measures and Clinical Outcomes in Healthy Individuals, Mild and Moderate Carpal Tunnel Syndrome Patients"
"This study aims to investigate ultrasonographic parameters of the median nerve in healthy individuals and patients with mild and moderate carpal tunnel syndrome (CTS).
- Conditions
- Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment, Electrophysiologic Study, Ultrasound
- Trial name
- NCT07408596
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Distal Radius Fractures
Treatment of Distal Radius Fractures in Elderly Patients
The purpose of this study is to create and test a treatment algorithm to guide the treatment of distal radius fractures in patients 65 and older and to obtain level-one evidence to determine the best method of treating distal…
- Trial name
- NCT00788190
- Testing
- Distal Radius Fracture Reduction, Conservative Management
- Where
- 2 sites in Canada
- Volunteers
- 65 people
- Sponsor
- Hand and Upper Limb Clinic, Canada
Age-Related Balance Impairment, Healthy Older Adults
Effects of Dynamic Neuromuscular Stabilization Exercises Versus Balance Exercises in Older Adults
The aim of this study is to compare the effects of Dynamic Neuromuscular Stabilization (DNS) based exercises and balance exercises on functional capacity, balance, muscle strength, and quality of life in older adults.
- Trial name
- NCT07495280
- Testing
- Dynamic Neuromuscular Stabilization Exercises, Balance Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Prostate Cancer, Prostate Adenocarcinoma
Initial Experience in Brazilian Single Center With High Intensity Focalized Ultrasound (HIFU) Prostate Cancer Therapy: Morbidity, Oncological and Functional Outcomes.
Prostate cancer (PCa) is the most prevalent non cutaneous cancer in occidental countries. In Brazil incidence was about sixty thousand new cases in 2016 and occupied second place as all cancer mortality, just behind lung cancer.
- Conditions
- Prostate Cancer, Prostate Adenocarcinoma, Transrectal High Intensity Focused Ultrasound
- Trial name
- NCT03255135
- Testing
- HIFU
- Where
- Brazil
- Volunteers
- 130 people
- Sponsor
- Hospital de Transplante Doutor Euryclides de Jesus Zerbini
Ventricular Remodeling, Left
Transcatheter Mitral Valve Repair for the Treatment of Mitral Valve Regurgitation In Heart Failure (The EVOLVE-MR Trial)
The study compares the effectiveness of treatment with MitraClip to medical therapy in improving the reduction of cardiovascular morbidity and functional capacity at 24 months, in patients with moderate functional mitral…
- Trial name
- EVOLVE-MR (NCT03891823)
- Testing
- MitraClip, Medical Therapy
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- Montreal Heart Institute
Mental Health, Loneliness
The Impact of a Telephone Reminiscence Program
The purpose of this study is to better understand how a telephone reminiscence program impacts reminiscence functions and mental health outcomes in community-dwelling older adults.This study will take 12 weeks to complete and…
- Conditions
- Mental Health, Loneliness, Social Isolation
- Trial name
- NCT05977608
- Testing
- Telephone Reminiscence Intervention
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Pulmonary Hypertension
Targeting the Right Ventricle in Pulmonary Hypertension
This study is looking to see if giving ranolazine to subjects on stable pulmonary hypertension specific therapies but with right ventricular dysfunction (RVEF <45%) would improve their outcome.
- Trial name
- NCT01839110
- Testing
- Ranolazine
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of Pennsylvania
Telerehabilitation
Tele-rehabilitation Through CIMT at Recovering the Function of the Upper Limb and Quality of Life
The current pandemic scenario is immensely challenging for healthcare professionals. Telerehabilitation,is a promising option that benefited many people, allowing continuity of therapeutic processes and promoting the admission of…
- Trial name
- TeleCIMT (NCT04877418)
- Testing
- TeleCIMT
- Where
- Chile
- Volunteers
- 22 people
- Sponsor
- Universidad de La Frontera
Critical Care, Rehabilitation
Differences in Frail and Non-frail Critically-ill Patients in Functional Outcomes
This is a prospective analysis of patient registry data of intensive care patients. The aim is to investigate if frailty is a predictor of decline of functional status of critically ill patients during their hospital stay.
- Conditions
- Critical Care, Rehabilitation, Outcome Assessment, Critical Illness
- Trial name
- DEFAULT (NCT03789305)
- Where
- Germany
- Volunteers
- 731 people
- Sponsor
- Technical University of Munich
Stroke
Multimodal Neurofunctional Profiling in Stroke
This prospective, observational cohort study aims to characterize multimodal neurofunctional profiles in patients with stroke. By integrating neurophysiological signals, neuroimaging data, clinical assessments, and biological…
- Trial name
- MNPS (NCT07411573)
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Vitamin D Deficiency (10 ng/mL to 30 ng/mL)
Vitamin D as a Supplement Against Falls in Elderly Study
The role of vitamin D deficiency on increased risk for falls and physical dysfunction is unclear. It is also unclear if taking vitamin D improves physical function and reduces fall risk in older adults.
- Trial name
- D-SAFE (NCT01827345)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Florida
Post Intensive Care Syndrome (PICS)
Post Intensive Care Accelerometery to Study and Support Recovery Outcomes
The primary purpose of this study is to find out whether a wrist-worn activity monitor can help healthcare professionals understand how people recover after they leave the intensive care unit (ICU), where they were cared for when…
- Trial name
- PICASSO (NCT07466446)
- Where
- 3 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Edinburgh
Trigger Finger
Early Postoperative Function After Open Versus Ultrasound-Guided Trigger Finger Release
Clinical outcomes after open trigger finger release are excellent. Minimally invasive techiques with ultrasound guidance theoretically offer advantages for faster recovery but this technique has not been compared prospectively…
- Trial name
- NCT07364695
- Testing
- UltraGuideTFR (Sonex Health, MN, USA)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Perioperative, Recovery
Comparing the Impact of Multimodal Prehabilitation to Aerobic Training on Patients Undergoing Thoracoscopic Lobectomy
In recent years, many studies have shown that prehabilitation based on aerobic training strategies could have a positive effect on the recovery of postoperative functional capacity in patients undergoing lung cancer surgery.
- Conditions
- Perioperative, Recovery, Prehabilitation, Thoracoschisis
- Trial name
- NCT04049942
- Testing
- Multimodal prehabilitation group, Aerobic training group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
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