Clinical trials: Functional Outcomes
Hip Arthropathy
Quality of Life, Functional Outcomes and Costs in Hip Arthroplasty
This prospective observational study aims to collect and analyse data on functional outcomes, quality of life indicators, and costs in patients undergoing primary total hip arthroplasty (hip replacement) surgery.
- Trial name
- NCT05882656
- Testing
- Questionnaire administration
- Where
- Russia
- Volunteers
- 85 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Dementia, Depressive Symptoms
Effects of Integrated Exercise on Sarcopenia, Depression Symptoms, and Quality of Life
The goal of this quasi-experimental (nonrandomized intervention) study is to investigate the effects of an integrated exercise intervention on sarcopenia, depression symptoms, and quality of life in community-dwelling older…
- Conditions
- Dementia, Depressive Symptoms, Quality of Life (QOL), Sarcopenia in Elderly
- Trial name
- NCT06637228
- Testing
- Move Your Hands, Feet, and Brain: Integrated Exercise Intervention Based on Taipei City Elderly Physical Activity Guidelines
- Where
- 2 sites in Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung University of Science and Technology
Cerebral Palsy, Robotics
Can Robot-Assisted Gait Training In Addition To Conventional Rehabilitation Provide Better Outcomes In Children With Cerebral Palsy?
A total of 26 patients who were diagnosed with CP [diplegic, with Gross Motor Function Classification System (GMFCS) level of 2-5] and who regularly participated in a rehabilitation programme were included in the study after…
- Trial name
- NCT04781101
- Testing
- conventional therapy, RoboGait®
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Okan University
Mitochondrial Function, Glucose Intolerance
Dose-response Relationship Between Exercise and Health Outcomes
In this study 11 healthy volunteers will perform high intensity exercise training during 4 weeks. The exercise frequency will increase progressively during the first three weeks, followed by a fourth week with lower exercise…
- Trial name
- NCT04753021
- Testing
- Exercise
- Where
- Sweden
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- The Swedish School of Sport and Health Sciences
Critical Illness
Intravenous Fish Oil Emulsion in Critically Ill Patients With High Inflammatory Status.
Critically ill patients can develop high levels of inflammation, which may contribute to organ damage, muscle loss, and difficulty recovering physical function.
- Trial name
- FOiL-INFLAMe (NCT07883447)
- Testing
- Omegaven (10% fish-oil emulsion; Fresenius-Kabi)
- Where
- Malaysia
- Volunteers
- 159 people
- Sponsor
- Lee Zheng Yii
Compensation Strategies, Serious Games
Feasibility of the Glenrose Grocery Game for Cognitive and Functional Outcomes in Older Inpatients
Older adults could benefit from computer serious games as a strategy for improving not only their cognitive functions but also their functioning and performance in daily activities, which are often compromised with age.
- Trial name
- NCT07584408
- Testing
- Experimental: Glenrose Grocery Game sessions, Standard cognitive rehabilitation
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Perineum; Tear, Traumatic, Anal Tear
Perineal Trauma After Jet Ski Accidents and Long-term Functional Outcomes Results
French multicentric retrospective cohort study including patients who underwent an ano-perineal trauma following a personal watercraft/jet-ski accident and that were treated in France from January 2017 to December 2023.
- Conditions
- Perineum; Tear, Traumatic, Anal Tear, Anal Incontinence
- Trial name
- TP-JET (NCT06368284)
- Testing
- Patients who experienced an ano-perineal trauma following a PWC/Jet-Ski accident
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Cardiac Rehabilitation, Exercise Therapy
Exercise Prescription in Cardiac Rehabilitation Mediated by Autonomic Function
Cardiac rehabilitation (CR) is an essential secondary prevention component in the treatment of cardiovascular diseases and one of the most cost- effective clinical interventions.
- Conditions
- Cardiac Rehabilitation, Exercise Therapy, Autonomic Nervous System Imbalance, Treatment Outcomes
- Trial name
- EXCARMA (NCT07288840)
- Where
- 2 sites in Portugal
- Volunteers
- 90 people
- Sponsor
- Instituto Politécnico de Leiria
Stroke
Pilot Study on Comparisons Between the Effectiveness of Mobile Video-guided and Paper-based Home Exercise Programs of Patients With Stroke Randomized Controlled Trial
This is a pilot study and a randomized, controlled, assessor-blinded clinical trial for patients who will complete the inpatient Stroke Rehabilitation Program in the Department of Medical and Geriatrics of Tai Po Hospital and…
- Trial name
- NCT03509363
- Testing
- Stroke physiotherapy home exercise video
- Where
- Hong Kong
- Volunteers
- 56 people
- Sponsor
- Tai Po Hospital
Male Infertility, Oligoasthenospermia
Investigation of the Effects of Stem Cell Supportive Treatment on Semen Parameters and Assisted Reproductive Techniques (ICSI) in Infertile Male Patients With Oligoasthenospermia(Decrease Sperm Number and Quality)
This study evaluated whether Stemregen® dietary supplementation could improve sperm quality and assisted reproductive treatment outcomes in men with severe oligoasthenozoospermia who had previously experienced at least one failed…
- Trial name
- STEMRN (NCT07800052)
- Testing
- Stemregen
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli University
Chronic Venous Insufficiency, CVI
Structured Home-Based Exercise and Education for Chronic Venous Insufficiency
The goal of this clinical trial is to learn whether a structured home-based exercise and education program can improve quality of life and leg symptoms in adults with chronic venous insufficiency.
- Trial name
- NCT07777978
- Testing
- Structured Home-Based Exercise and Education Program, Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Abant Izzet Baysal University
Anterior Cruciate Ligament Injuries
Comparative Study of Functional Outcomes Between Peroneus Longus and Hamstring Tendon Autografts in Arthroscopic ACL Reconstruction
This is a prospective, single-blinded, randomized controlled trial. Sixty patients (≥18 years) with an isolated ACL injury will be randomly assigned to receive an ACL reconstruction using either a Peroneus Longus Tendon (PLT)…
- Trial name
- NCT07346326
- Testing
- Hamstring Tendon Autograft Harvest and ACL Reconstruction, Peroneus Longus Tendon Autograft Harvest and ACL Reconstruction
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Khyber Medical University Peshawar
Knee Injuries, Sport Injury, Knee Injuries
Effects of Mulligan Mobilization With Movement Versus Kinesiotaping and Placebo on Knee Function and Injury -Related Outcomes in Basketball Players
This is a randomized RTC study where the KOS-ADLS score of athletes' functionality and the OSTRC score of sports overuse injuries were used as outcomes, which were measured before the start of treatment, 1 hour and 2 weeks after…
- Trial name
- Sport _MWM_RTC (NCT07510243)
- Testing
- Mulligan Mobilization with movement MWM, Kinesiotaping
- Where
- Albania
- Volunteers
- 60 people
- Sponsor
- University Aleksander Moisiu Durres
Air Pollution, mHealth Intervention
1/2- Bangladesh Center for Global Environmental and Occupational Health- Bangladesh
Almost 3 billion people worldwide, including 89% people in Bangladesh, are exposed to harmful household air pollutants (HAP) emitted from combustion of biomass (wood, agricultural residue, cow dung, etc.) fuel use for cooking.
- Conditions
- Air Pollution, mHealth Intervention, Cardiopulmonary Function, Immune Function
- Trial name
- GEOHealth-II (NCT05570552)
- Testing
- mHealth based behavioral change communication intervention
- Where
- Bangladesh
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Sarcopenia, Gestational Diabetes Mellitus (GDM)
Sarcopenia in Gestational Diabetes
Sarcopenia is a syndrome characterized by loss of skeletal muscle mass and strength, and physical performance deterioration. Prevalence of sarcopenia in elderly people is remarkably high (prevalence of about 25% in 60+ years…
- Conditions
- Sarcopenia, Gestational Diabetes Mellitus (GDM), Pregnancy Complications, Adverse Maternal and Neonatal Outcomes
- Trial name
- SiGnal-D (NCT06876090)
- Testing
- Sarcopenia tests (for muscle mass, muscle function, physical performance), Oral Glucose Tolerance Test, Montreal Cognitive Assessment
- Where
- 3 sites in Austria, Italy
- Volunteers
- 200 people
- Sponsor
- Istituto di Neuroscienze Consiglio Nazionale delle Ricerche
Ischemic Stroke, Hemiplegia
Repetitive Transcranial Magnetic Stimulation for Motor Recovery After Ischemic Stroke (rTMS-MOTOR)
Ischemic stroke is a leading cause of long-term motor disability, frequently resulting in hemiplegia and limitations in daily activities and quality of life.
- Conditions
- Ischemic Stroke, Hemiplegia, Motor Function Impairment
- Trial name
- rTMS-MOTOR (NCT07369648)
- Testing
- Active repetitive transcranial magnetic stimulation, Conventional motor rehabilitation
- Where
- Vietnam
- Volunteers
- 66 people
- Sponsor
- Hanoi Medical University
Liver Transplantation, Ischaemia Reperfusion Injury
Effect of Discarding Initial Reperfusion Blood on Hemodynamics, Liver Function, and 30-Day Outcomes in Liver Transplantation
Hepatic reperfusion during liver transplantation remains a critical phase associated with significant hemodynamic and systemic disturbances, despite advances in surgical and anesthetic management.
- Conditions
- Liver Transplantation, Ischaemia Reperfusion Injury, Perioperative Complications
- Trial name
- NCT07631689
- Testing
- Reperfusion Blood Discard, Standard Liver Transplantation
- Volunteers
- 132 people
- Sponsor
- University of Sao Paulo General Hospital
Osteoarthritis (OA) of the Knee, Osteoarthritis
Functional and Clinical Outcomes of Hyaluronic Acid and Steroid Injections in Bilateral Knee Osteoarthritis
The aim of this study is to compare functional and clinical outcomes of intraarticular injections of hyaluronic acid and steroids in patients with bilateral knee osteoarthritis.
- Conditions
- Osteoarthritis (OA) of the Knee, Osteoarthritis, Osteoarthritis in the Knee, Osteoarthritis of Knee
- Trial name
- NCT06717529
- Testing
- Sodium hyaluronate (hyaluronic acid), Methylprednisolone Acetate Injection
- Where
- Bosnia and Herzegovina
- Volunteers
- 65 people
- Sponsor
- Edin Mešanović
Knee Osteoarthritis
Functional and Quality of Life Outcomes Following Viscosupplementation for Knee Osteoarthritis
This study will compare changes in outcomes following viscosupplementation for knee osteoarthritis.
- Trial name
- NCT01447303
- Testing
- Subject outcomes following viscosupplementation of the knee
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Florida
Acute Ischemic Stroke
Effect of Human Urinary Kallidinogenase on Inflammatory Factors in Acute Ischemic Stroke (KIF-AIS)
The goal of this clinical trial is to explore the changes in the expression levels of inflammatory factors before and after the early treatment of Human Urinary Kallidinogen (HUK) in the acute ischemic stroke.
- Trial name
- NCT06696703
- Testing
- Human urinary kininogenase(HUK)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
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