Clinical trials: Functional Outcomes
Acute Respiratory Distress Syndrome (ARDS)
Clinical and Functional Outcomes of Critically Ill Patients With COVID-19
People affected by Severe Acute Respiratory Syndrome (SARS) by COVID-19 virus my require a long lasting invasive mechanical ventilation life support.
- Trial name
- COVIDPTcare (NCT05024500)
- Testing
- ARDSNet table, Driving Pressure, Electrical Impedance Tomography
- Where
- 4 sites in Brazil
- Volunteers
- 75 people
- Sponsor
- University of Pernambuco
Knee Disease, Bone Cancer
Functional Outcomes of Knee Protheses for Malignant Tumours of Bone
The placement of mega knee prosthesis is a necessity after a large tumor resection and oncological. These mega knee prostheses implanted in the context of oncological surgery have been very few evaluated in the literature.
- Trial name
- ISOMUTAR (NCT04650594)
- Testing
- MUTARS® modular reconstruction prostheses
- Where
- France
- Volunteers
- 9 people
- Sponsor
- University Hospital, Lille
Von Hippel-Lindau Disease, Central Nervous System Hemangioblastoma
Pediatric Von Hippel-Lindau Disease: Natural History, Predictive Factors, and Long-Term Functional Outcomes of Central Nervous System Hemangioblastomas
Von Hippel-Lindau (VHL) disease is a rare hereditary cancer predisposition syndrome associated with the development of central nervous system hemangioblastomas from childhood.
- Trial name
- VHL-PED-CHB (NCT07705529)
- Where
- 3 sites in France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteo Arthritis Knee, Osteoarthritis
Mako Functionally Aligned Total Knee Arthroplasty vs Mako Mechanically Aligned Total Knee Arthroplasty
This study evaluates outcomes of robotic-arm assisted mechanically aligned total knee arthroplasty [MA TKA] versus robotic-arm assisted functionally aligned total knee arthroplasty [FA TKA].
- Conditions
- Osteo Arthritis Knee, Osteoarthritis, Surgery
- Trial name
- NCT04092153
- Testing
- Total knee arthroplasy
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University College, London
Use of Tourniquet in Total Knee Arthroplasty
Effects of the Use of Tourniquet in Total Knee Arthroplasty on the Clinical and Functional Outcomes With 5 Years of Follow up
This study is randomized controlled trial with 5 years follow up and involved 101 patients divided in two groups; group A in which tourniquet was used in total knee arthroplasty while group B in which tourniquet was not used.
- Trial name
- NCT04469166
- Testing
- tourniquet, No tourniquet
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Cardiac Surgeries
Early Cardiopulmonary Rehabilitation Bundle Functional Capacity and Outcomes of Cardiac Surgeries Patients
The goal of this quasi-experimental study is to evaluate the impact of Early. Cardiopulmonary Rehabilitation Bundle on Functional Capacity and Outcomes in Cardiac Surgeries Patients The main question is Patients receive early…
- Trial name
- NCT07724353
- Testing
- Early cardiopulmonary rehabilitation bundle
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE)
Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)
This international study, organized by Healing Hope International, is an observational registry designed to collect real-world data on participants living with chronic hypoxic ischemic encephalopathy (HIE) who receive an emerging…
- Conditions
- Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE), Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest, Hypoxic Ischemic Encephalopathy of Newborn
- Trial name
- GEN-HOPE (NCT07264166)
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Healing Hope International
Cancer of Muscle
Functional Outcomes and HRQoL in Upper-extremity Sarcoma Patients After Limb Salvage
This study aims to assess the functional ability and health-related quality of life (HRQoL) of upper extremity sarcoma patients who have undergone limb salvage surgery.
- Trial name
- NCT02380651
- Testing
- Limb salvage
- Where
- 2 sites in Finland
- Volunteers
- 55 people
- Sponsor
- Helsinki University Central Hospital
Hemophilia
Outcomes of Prophylaxis and On-demand Treatment for Severe Hemophiliacs and Collection of Baseline Data in Hemophiliacs in Taiwan
Primary prophylaxis in severe hemophiliacs is defined that prophylaxis therapy starts before 2 years of age and prior to any clinically evident joint bleeding or after first joint bleeding and prior to the onset of joint damage…
- Trial name
- NCT02908243
- Testing
- collection of baseline data
- Volunteers
- 350 people
- Sponsor
- Taiwan Society of Thrombosis and Hemostasis
Soft Tissue Sarcoma of the Lower Extremity, Bone Sarcoma of the Lower Extremity
Functional and Structural Outcomes Following Childhood Bone or Soft Tissue Sarcomas of the Lower Extremity
Soft tissue and bone sarcomas of the lower extremity pose significant challenges for affected individuals, often associated with considerable burden.
- Conditions
- Soft Tissue Sarcoma of the Lower Extremity, Bone Sarcoma of the Lower Extremity, Childhood and Adolescent Cancer
- Trial name
- FOCUS (NCT06737172)
- Where
- 2 sites in Germany
- Volunteers
- 18 people
- Sponsor
- Technical University of Munich
Rhegmatogenous Retinal Detachment, Retinal Detachment
Anatomical and Functional Outcomes of Pneumatic Retinopexy for Retinal Detachment: A 2-Year Case Series
The goal of this observational study is to evaluate the 2-year anatomical and functional outcomes of pneumatic retinopexy in phakic adult patients with superior rhegmatogenous retinal detachment meeting adapted PIVOT eligibility…
- Trial name
- NCT07794163
- Testing
- Pneumatic Retinopexy
- Where
- Colombia
- Volunteers
- 33 people
- Sponsor
- Clinica Oftalmologica Paredes
Systemic Sclerosis
Hand Function Impairment in Systemic Sclerosis: Outcomes, Mechanisms and Experience (HANDSOME)
Almost 90% of systemic sclerosis (SSc) patients experience hand function limitation, which leads to impaired daily functioning and work participation.
- Trial name
- NCT06133244
- Testing
- Imaging, blood samples, fuctional tests and physical examination
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- UMC Utrecht
Rotator Cuff Tear
Functional Outcomes Following Shoulder Surgery: A Prospective Database
The purpose of this prospective database is to investigate the long-term functional status of patients who have undergone various types of rotator cuff repair surgery.
- Trial name
- NCT00253864
- Testing
- Single row, Double row
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Ottawa Hospital Research Institute
Congenital Heart Defect, Executive Function
Improving Neurodevelopmental Outcomes in Children With Congenital Heart Disease: An Intervention Study
Each year, approximately 1 child in every 100 is born with Congenital Heart Disease (CHD), making it the most common birth defect.
- Conditions
- Congenital Heart Defect, Executive Function, Children, Neurodevelopmental Disorders
- Trial name
- NCT03023644
- Testing
- Cogmed Working Memory Training
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Boston Children's Hospital
Long Covid
Effects of a Physical Rehabilitation Program on Long COVID
The objective of this clinical trial is to analyze the clinical, functional, and laboratory effects of a rehabilitation protocol designed for patients with long COVID; it may include any of the following: sex/gender, age groups…
- Trial name
- ReabCovid (NCT07651371)
- Testing
- Physical rehabilitation, Treadmill ergometer, Pulley
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Universidade do Estado do Pará
Sleep, Quality of Life
Effects of a Healthy Lifestyle Program on Health Outcomes in Older Adults
Medical condition or disease under investigation : Quantitative and qualitative aspects of sleep, quality of life, functional ability and well-being in older adults (>55years) Purpose of clinical trial : To study the prospective…
- Conditions
- Sleep, Quality of Life, Functional Ability, Well-being
- Trial name
- NCT03576209
- Testing
- healthy lifestyle program
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Behavior, Health
Train Your Brain: A Pilot Project to Improve Memory and Decision Making
The goal of this clinical trial is to pilot a computer-based working memory training program to improve delay discounting (DD) and prevent substance use among at-risk adolescents in a traditionally underserved area.
- Trial name
- NCT05879198
- Testing
- Computer-based Intervention
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Henry Ford Health System
Plantar Fascitis
Active Release Technique vs. Dynamic Soft Tissue Mobilization for Plantar Pain
Plantar fasciitis is one of the most common causes of heel pain encountered in musculoskeletal and orthopedic physiotherapy practice.
- Trial name
- NCT07916363
- Testing
- Active Release Technique (ART), Dynamic Soft Tissue Mobilization
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- University of Management and Technology Lahore
Asthma Management, Time Restricted Eating
Investigating the Impact of Early Time-Restricted Eating on Health Outcomes and Quality of Life in Adults With Mild Controlled Asthma Compared to Healthy Adults
This study aims to explore how early time-restricted eating (eTRE) - where all daily meals are eaten within a specific time window - affects health and quality of life in adults.
- Trial name
- eTRE (NCT07345572)
- Testing
- Early Time-Restricted Eating (eTRE) and Habitual Diet (HD), Habitual Diet (HD) and Early Time-Restricted Eating (eTRE)
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- De Montfort University
Distal Femoral Musculoskeletal Tumors
Functional Outcomes and Quality of Life in Musculoskeletal Tumor Patients With Distal Femoral Megaprostheses
This study aims to evaluate the functional outcomes of patients with distal femur tumor prostheses in comparison to a matched control group.
- Trial name
- FOQ-DFP (NCT06282198)
- Where
- Spain
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
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