Clinical trials: Functional Outcomes
Mild Cognitive Impairment (MCI), Sarcopenia
Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment
Mild Cognitive Impairment (MCI) in older adults is linked to muscle loss (sarcopenia) and can lead to dementia, with pain further impacting cognitive and physical performance.
- Trial name
- NCT06828926
- Testing
- Tai Chi
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ohio University
Cancer, Lung Cancer
PROStep: A Feasibility Trial Using PROs and Step Data to Monitor Patients With Lung and GI Cancers
Telemedicine allows clinicians to utilize modern telecommunication technology to provide healthcare services to patients including remote symptom monitoring.
- Conditions
- Cancer, Lung Cancer, Gastro-intestinal
- Trial name
- PROStep (NCT04616768)
- Testing
- PRO questionnaire, Step monitoring, Active nudge text feedback
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Carpal Tunnel Syndrome
Effects of Two Different Kinesiotaping Techniques in Carpal Tunnel Syndrome
This study aims to evaluate the clinical, functional, and ultrasonographic effects of two different kinesiotaping techniques added to a standard exercise and night splint program in the treatment of Carpal Tunnel Syndrome (CTS).
- Trial name
- CTS-TAPE (NCT07742293)
- Testing
- I-Strip Kinesiotaping and Standard Therapy, Button Hole Kinesiotaping and Standard Therapy, Standard Exercise and Splint Therapy
- Volunteers
- 90 people
- Sponsor
- Kayseri City Hospital
Cognitive Function
Radicle Clarity: A Study of Health and Wellness Products on Mental Clarity and Health Outcomes
A randomized, blinded, placebo-controlled direct-to-consumer study of health and wellness products on mental clarity and other health outcomes
- Trial name
- NCT05652725
- Testing
- Clarity Active Study Product 1.1 Usage, Clarity Active Study Product 2.1 Usage, Clarity Active Study Product 3.1 Usage
- Where
- United States
- Volunteers
- 4,826 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Liver Disease, Cardiovascular Disease
Liver Function Measured by HepQuant-SHUNT in the Prediction of Outcomes in Patients With Heart Disease
Background: It is still difficult to predict the outcome in patients requiring Fontan Revisions and in those who have evidence of congestive hepatopathy and probable cirrhosis requiring major cardiac surgery including heart…
- Trial name
- NCT02506335
- Testing
- Cholate testing
- Volunteers
- 14 people
- Sponsor
- Northwestern University
Dislocation of Midcarpal Joint
Arthroscopic Midcarpal Wrist Arthrodesis: Clinical and Functional Outcomes
All cases of midcarpal wrist arthritis treated surgically with arthroscopic partial wrist fusion with cannulated screws from January 2015 to December 2017 will be reviewed.
- Trial name
- NCT03763552
- Testing
- arthroscopic wrist arthrodesis
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- University of Zurich
Specific Learning Disability, Mental Health Issue
Biopsychosocial Outcomes of Mindfulness-based Instruction
Over 20% of adolescents living in the United States have a diagnosable psychiatric disorder. However, most adolescents who need mental health services do not receive them due to many reasons, including low resources in families…
- Trial name
- MindUP (NCT05787483)
- Testing
- MindUP group, active control group
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity, Bariatric Surgery
Obesity Surgery, Counseling, and Psychological Well-Being
Obesity has become a global epidemic causing enormous human and economic costs. Incidence rates have doubled over the last few decades and obesity-related illnesses such as diabetes and cardiovascular diseases now constitute one…
- Trial name
- NCT01865227
- Testing
- Group Counseling
- Where
- 2 sites in Jordan, United Arab Emirates
- Volunteers
- 100 people
- Sponsor
- American University of Sharfah
Sarcopenia, Acute Stroke
Sarcopenia in Acute Ischemic Stroke
The objective of this observational study is to determine the prevalence of sarcopenia in patients aged 50 years and older with acute ischemic stroke, to characterize its trajectory during the acute phase using instrumental…
- Trial name
- NCT07764172
- Where
- Russia
- Volunteers
- 400 people
- Sponsor
- University Clinical Hospital na V.V.Vinogradov (branch of RUDN university na Patrice Lumumba)
Benign Prostatic Hyperplasia (BPH)
The FLOW Registry.
The purpose of this study is to create a database and prospective registry for data collection on patients with benign prostatic hyperplasia undergoing Aquablation of the prostate.
- Trial name
- NCT07430423
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- University of Chicago
Developmental Dysplasia of the Hip
Mid-term Functional Comparisons of Unilateral and Bilateral Developmental Dysplasia of the Hip
The annual number of live births in Türkiye is 1,112,859 in 2020 and the estimated incidence of developmental dysplasia of the hip (DDH) is between 5 and 15 per 1000 live births.
- Trial name
- NCT05853510
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Pamukkale University
Rheumatoid Arthritis, Atherosclerotic Ischemic Disease
Coronary Computed Tomography Angiography In Rheumatoid Arthritis Study
The Coronary Computed Tomography Angiography in Rheumatoid Arthritis study is part of the multinational, prospective, observational Autoimmunity and Atherosclerosis in Rheumatic Diseases cohort (https://atacc-rd.com) that…
- Conditions
- Rheumatoid Arthritis, Atherosclerotic Ischemic Disease, Pulmonary Disease, Depressive Disorder
- Trial name
- COTIRA (NCT07363980)
- Where
- 4 sites in Denmark
- Volunteers
- 4,000 people
- Sponsor
- Ellen Margrethe Hauge
Constipation, Constipation - Functional
The Impact of Respiratory Muscle Training and Patient Education on Chronic Constipation Outcomes
The primary aim of this study will be to determine if a respiratory muscle training program that includes both inspiratory muscle training (IMT) and expiratory muscle training (EMT), targeted at improving respiratory muscle…
- Conditions
- Constipation, Constipation - Functional, Dyssynergia
- Trial name
- NCT05823259
- Testing
- Hybrid Telehealth Program: Respiratory Muscle Training and Patient Education, Standard Physical Therapy Care
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Miami
Osteoarthritis, Knee, Arthropathy of Knee
Total Knee Arthroplasty: Fast Track Protocol is the Future?
Fast-track total knee arthroplasty (TKA) is a well-established concept including optimized logistics and evidence-based treatment, focusing on minimizing surgical stress and improved post-operative recovery.
- Trial name
- FastTrack-G (NCT03869996)
- Testing
- fast track care protocol, standard care protocol
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Hemophilia A
Patient Functioning and Well-being, Economic, and Clinical Impact of Hemophilia A and Its Treatment
The purpose of the study is to improve the understanding of key patient reported outcomes such as quality of life as well as clinical outcomes in hemophilia A, in a global real world setting.
- Trial name
- ECHO (NCT02396862)
- Testing
- Available Recombinant, and Human Factor VIII products incl. Kogenate FS (Recombinant Factor VIII, BAY14-2222)
- Where
- 10 sites in United States, Japan and 2 more
- Volunteers
- 272 people
- Sponsor
- Bayer
Muscle Loss, Protein
PRotein Optimization With eXercise to Improve MUscle Mass and Functional outcomeS
The investigators have designed a 2-center, pilot feasibility, randomized controlled trial (PROXIMUS) to determine the feasibility and safety of a larger multi center, randomized open-label trial comparing high protein combined…
- Conditions
- Muscle Loss, Protein, Mobility, Pediatric ALL
- Trial name
- PROXIMUS (NCT05296096)
- Testing
- Protein dosage and rehabilitation team delivered exercise prescription
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Boston Children's Hospital
Depression and Quality of Life, Treatment Resistant Depression (TRD)
Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression
This observational study investigates the use of Esketamine Intranasal Spray in patients with Treatment-Resistant Depression in Real-World Settings.
- Conditions
- Depression and Quality of Life, Treatment Resistant Depression (TRD), Anhedonia, Apathy
- Trial name
- ESKPSY (NCT07146503)
- Testing
- Esketamine (Intranasal Spray)
- Where
- 5 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Riccardo Guglielmo
Arthroplasty, Replacement, Knee, Nerve Block
Study to Evaluate ACB Versus FNB Early Postoperative Period Functional Outcomes After TKA
The purpose of this study is to determine if patients undergoing a Total Knee Arthroplasty who receive a single shot Adductor Canal nerve block and local infiltration will have improved functional outcomes compared to individuals…
- Trial name
- ACB (NCT02218814)
- Testing
- Adductor Canal Block, Bupivacaine, Femoral Nerve Block, Bupivacaine
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- George Macrinici
Traumatic Brain Injury, Vestibular Deficits
Traditional Balance vs Vibrotactile Feedback Training for Vestibular Rehabilitation
The goal of this clinical research study at RIC is to determine the value and benefit of the SK multimodal balance training system through independent clinical evaluations.
- Trial name
- NCT01672658
- Testing
- Sensory Kinetics Balance System, Traditional Vestibular Rehabilitation
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Shirley Ryan AbilityLab
Macular Edema, Retinal Vein Occlusion
Functional and Anatomical Outcomes of Dexamethasone Intra-vitreal Implant in Patients with Resistant Macular Edema Secondary to Retinal Vein Occlusion After Intravitreal Anti-VEGF Injection
Retinal vein occlusion (RVO) is one of the most common causes of vision loss due to retinal vascular disease. Incidence of RVO has been raised in the last years due to increased coexisting systemic vascular risk factors as…
- Trial name
- NCT05003258
- Testing
- Intravitreal injection of Dexamethasone implant
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Assiut University
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