Clinical trials: Functional Outcomes
Acquired Brain Injury
Neurocognitive Rehabilitation Using Virtual Reality
Objective: To determine whether immersive virtual reality (VR) treatment interventions improve executive dysfunction and complex attention deficits in patients with brain injury compared with standard neurorehabilitation, and…
- Trial name
- NCT04017091
- Testing
- Virtual Reality Cognitive Training
- Volunteers
- 33 people
- Sponsor
- Baylor Research Institute
Uterine Prolapse
Combined Effects of Pelvic Floor Retraining and Hypopressive Exercises in Uterine Prolapse Outcomes
One common pelvic floor condition, particularly in postpartum or later life, is uterine prolapse. It is caused by weak pelvic floor muscles and connective tissues and often presents with pain, urinary incontinence, and reduced…
- Trial name
- NCT07642180
- Testing
- Functional Movement Retraining + Hypopressive Exercises, Pelvic Floor Functional Movement Retraining
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Coccydynia, Coccygodynia
Shock Wave Therapy Versus High-Intensity Laser Therapy for Coccydynia (Tailbone Pain)
This study compares shock wave therapy with high-intensity laser therapy for tailbone pain, also called coccydynia. It includes adults aged 18 to 65 years who have had tailbone pain for at least 3 months and continue to have…
- Trial name
- NCT07898514
- Testing
- Extracorporeal Shock Wave Therapy, High-Intensity Laser Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ahmet Sümen
Breast Cancer, Metastasis
Assessing Functional Status Needs Via PRO Measures for Pts With Metastatic Breast Cancer
The purpose of this single-site non-randomized study is to identify areas of need related to functional status and overall health, including nutrition and mental health in subjects with metastatic breast cancer (MBC).
- Trial name
- NCT05755347
- Testing
- General health survey questionnaires, PROMIS Cancer Function Brief 3D profile questionnaires, FACT-G questionnaires
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Mitral Regurgitation, Heart Failure
MitraClip for the Treatment of Moderate Functional Mitral Regurgitation: EVOLVE-MR
This study evaluates the addition of transcatheter mitral valve repair with the MitraClip device to medical treatment in patients with heart failure and moderate functional mitral regurgitation to determine the impact of left…
- Conditions
- Mitral Regurgitation, Heart Failure, Mitral Valve Regurgitation Due to Cardiomyopathy (Disorder)
- Trial name
- EVOLVE-MR (NCT03705312)
- Testing
- Transcatheter mitral valve repair, Guideline-directed medical therapy
- Where
- Canada
- Volunteers
- 174 people
- Sponsor
- Montreal Heart Institute
Knee Osteoarthritis
Effect of Probiotic Supplements on Osteoarthritis Outcomes
Dysbiosis of the gut microbiota is believed to contribute to the development and progression of osteoarthritis (OA), suggesting a role for probiotics in the treatment of OA.
- Trial name
- ProOA23 (NCT06459700)
- Testing
- Probiotic supplements
- Where
- Sweden
- Volunteers
- 86 people
- Sponsor
- Lund University
Pediatric Obesity, Executive Function
Cognitive Aspects of Response to Treatment for Weight-related Health to Improve Eating and Exercise Earlier in Life
We plan to examine whether child and parental cognitive/executive function predict body composition outcomes and adherence to a 6-month protocol of Family-Based Behavioral Treatment (FBT), for pediatric obesity.
- Trial name
- CARTWHEEL (NCT03329300)
- Testing
- Family-based Behavioral Treatment (FBT)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Alabama at Birmingham
Achilles Tendon Rupture
Achilles Tendon Rupture Patient Outcomes at 12 Months
Achilles tendon rupture is a common injury that can significantly impact strength, function, and quality of life. While non-surgical management using structured rehabilitation protocols such as the Swansea Morriston Achilles…
- Trial name
- ATR-12 (NCT07391553)
- Testing
- Non-Surgical Management Using the SMART Protocol
- Where
- 2 sites in United Kingdom
- Volunteers
- 115 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Posttraumatic Stress Disorder
Imaging Outcomes of Cognitive Behavioral Therapy (CBT) for Battered Women With Posttraumatic Stress Disorder
Identifying neural mechanisms of posttraumatic stress disorder (PTSD) treatment could help elucidate reasons for variable treatment response and identify novel treatment targets.
- Trial name
- NCT01517672
- Testing
- Cognitive Trauma Therapy for Battered Women (CTT-BW)
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Stroke, Ischemic, Subacute Stroke
The Effect of BWSTT on Neuroendocrine Profile and Functional Recovery in Stroke Patients
The purpose of this study is to evaluate the impact of intensive Body Weight Support Treadmill Training (BWSTT) on the neuroendocrine system and functional recovery in patients during the subacute phase of ischemic stroke.
- Trial name
- NCT07443150
- Testing
- Body Weight Support Treadmill Training (BWSTT), Overground Training
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Jagiellonian University
Chondral Defect
The Biomechanical Outcomes of Autologous Chondrocyte Implantation
Injury to the knee can damage the lining of the knee's bones, called cartilage. Cartilage injuries cause pain and limit movement, making activities like walking, playing sports, and working difficult.
- Trial name
- NCT06921889
- Testing
- Autologous Chondrocyte Implantation (ACI)
- Where
- 7 sites in United Kingdom
- Volunteers
- 47 people
- Sponsor
- University of Manchester
Joint (Knee or Hip Replacement), Infection as Complication of Medical Care
Swiss Revision Cohort
This study follows patients with infections after a joint replacement over time. During follow-up, treatment outcomes are carefully measured to determine whether the infection can be cured.
- Trial name
- REVCO (NCT07473089)
- Testing
- Revision for periprosthetic joint infections of the hip, knee, shoulder, elbow or ankle
- Where
- 5 sites in Switzerland
- Volunteers
- 329 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Total Knee Arthroplasty (Replacement)
A Study on the Physiological Outcomes of the Enhanced Recovery After Surgery Model in Older Adults Undergoing Total Knee Arthroplasty
With the advent of an aging society, the demand for total knee arthroplasty (TKA) continues to increase. Postoperative recovery is influenced not only by the surgical procedure itself but also by pain control, joint function, and…
- Trial name
- NCT07828418
- Testing
- Enhanced Recovery After Surgery (ERAS) Care Pathway, Usual Perioperative Care
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Carpal Tunnel Syndrome (CTS)
Pregabalin Phonophoresis for Carpal Tunnel Syndrome Pain
Carpal tunnel syndrome (CTS) is a common condition caused by pressure on the median nerve in the wrist, leading to pain, numbness, and weakness in the hand. Oral medications for nerve pain can have significant side effects.
- Trial name
- PREG-CTS-USG (NCT07613476)
- Testing
- Pregabalin Phonophoresis, Therapeutic Ultrasound
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Faisalabad
Cognitive Change, Diet, Healthy
Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)
The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in…
- Conditions
- Cognitive Change, Diet, Healthy, Metabolic Syndrome, Protection Against
- Trial name
- NCT06605898
- Testing
- MIND Diet, Control Diet
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Urinary Incontinence in Old Age, Sedentary Behavior
Urinary Incontinence and Sedentary Behaviour in Nursing Homes
The increase of the older adult population in the past years has generated an important impact on chronic conditions and geriatric syndromes like dementia, falls and urinary incontinence (UI).
- Trial name
- OsoNaH (NCT04297904)
- Testing
- Sedentary behaviour, Urinary Incontinence
- Where
- 15 sites in Spain
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Post-mastectomy Breast Reconstruction
Long Term Function Outcomes and Pain in Implant-based Post-mastectomy Breast Reconstruction
The objective of this proposal is to broadly assess patient physical functioning following breast reconstruction.
- Trial name
- NCT04477538
- Testing
- Post-mastectomy breast reconstruction physical well-being survey
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Washington University School of Medicine
Lumbar Radiculopathy
Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes
This randomized control trial will compare opioid use, pain, and functional outcomes following decompression surgery for single-level lumbar radiculopathy in patients who undergo placement of corticosteroid epidural injection…
- Trial name
- NCT03543033
- Testing
- Corticosteroid injection
- Where
- United States
- Sponsor
- Lahey Clinic
Aging, Mild Cognitive Impairment
A Study of Characterizing Cognitive Decline and Functional Cardiac Senescence in Healthy Korean Volunteers
Although aging process appears to be generally characterized, investigators have been paid much attention to the specific target molecules, which leads to discover the clinical markers of the senescence.
- Conditions
- Aging, Mild Cognitive Impairment, Angina Pectoris
- Trial name
- NCT01590706
- Where
- South Korea
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Korea Institute of Oriental Medicine
Transfemoral Amputees
Thigh Reduction Surgery of Above Knee Amputee Residual Limbs to Improve Prosthesis Fit and Patient Outcomes
The purpose of our study is to improve the fit and function of prosthetic sockets for above the knee amputees through the use of an outpatient thigh reduction surgical procedure.
- Trial name
- NCT02346019
- Testing
- Medial thighplasty with or without thigh liposuction
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Shirley Ryan AbilityLab
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