Clinical trials: Functional Outcomes
Osteoarthritis Thumbs, Rhizarthrosis
Pinch Grip and Functional Outcomes Between Hematoma Distraction Arthroplasty Versus Ligament Reconstruction Tendon Interposition Arthroplasty in Trapeziometacarpal Osteoarthritis.
To date, there is no gold standard for the treatment of severe trapeziometacarpal joint osteoarthritis. Despite the fact that new procedures have been described, techniques such hematoma distraction or ligament reconstruction…
- Conditions
- Osteoarthritis Thumbs, Rhizarthrosis, Trapeziometacarpal (TMC) Arthrosis
- Trial name
- Rhizarthrosis (NCT06858800)
- Testing
- LTRI technique, HDA technique
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Hospital de la Santa creu i Sant Pau - Barcelona
Attention Deficit Hyperactivity Disorder
Efficacy of Cognitive Behavioral Therapy in Treatment of Adults With Attention Deficit Hyperactivity Disorder
The purpose of the project is to evaluate the efficacy of cognitive behavioral therapy (CBT) for adults with attention deficit hyperactivity disorder (ADHD) with and without stimulant medication and compare it to medication…
- Trial name
- NCT02210728
- Testing
- methylphenidate or amphetamine product, Cognitive behavioral therapy
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Lily Hechtman
Hearing Impaired Children
Outcomes of Cochlear Implantation in Pediatrics
The cochlear implant (CI) is the most important progress in the treatment for adults and children with severe to profound bilateral sensorineural hearing loss who do not receive adequa¬te benefit from hearing aids and making…
- Trial name
- NCT04092231
- Testing
- Early speech perception test
- Volunteers
- 30 people
- Sponsor
- Amira Mohmed Ahmed Bakr
Chest Pain, CAD
Comparing a Diagnostic and Treatment Strategy of Upfront CTCA With SOC in Patients With Chest Pain and Suspected CAD
Rationale: Patients with chest pain usually undergo multiple diagnostic examinations to demonstrate or rule out atherosclerotic coronary artery disease (CAD).
- Trial name
- CLEAR-CAD (NCT05344612)
- Testing
- CT Coronary Angiography
- Where
- Netherlands
- Volunteers
- 6,444 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Premature Birth
Follow-Up at 6 Years of a Cohort of Children Born Very Prematurely
Utilization of nitric oxide (NO) therapy has been related to a trend towards short term improvement in very premature infants. A two year follow-up of children treated soon after birth with NO in the neonatal period, suggests…
- Trial name
- NCT00390065
- Testing
- Nitric Oxide
- Where
- 2 sites in France
- Volunteers
- 108 people
- Sponsor
- Maternite Regionale Universitaire
Anterior Cruciate Ligament Injuries, Arthroscopy
Functional Outcomes Comparison in Patients Using Knee Brace Post ACL Reconstruction With Autograft Bone Quadricep Tendon
This study is a study looking for the relationship between variables with a prospective cohort design to determine functional outcomes subjectively and objectively in patients with and without braces after ACL reconstruction with…
- Conditions
- Anterior Cruciate Ligament Injuries, Arthroscopy, Braces
- Trial name
- ACL (NCT05457452)
- Testing
- Knee Brace
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Anterior Knee Pain Syndrome
Knee Isometric Program (KIP) Home Exercise Programs (HEP) Physical Therapy (PT) Study
The purpose of this study is to evaluate the efficacy of a knee isometric program (KIP) as compared to the current gold standard treatment for anterior knee pain (Patellofemoral Clinical Practice Guideline [CPG] - Academy of…
- Trial name
- NCT06536426
- Testing
- Knee Isometric Program (KIP)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- The Methodist Hospital Research Institute
Tricuspid Valve Insufficiency
"Atriogenic Tricuspid Selected, Omics Profile, Multimodality Imaging and Clinical Outcomes"
The aim of our study is to investigate the molecular mechanisms underlying remodeling of the tricuspid valve apparatus in patients with ITF and isolated AF, in comparison with patients with ITF from right ventricular remodeling…
- Trial name
- ATOMIC (NCT05724225)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Prostate Hyperplasia, Thulium Fiber Laser
Thulium Fiber Laser Enucleation of the Prostate: Learning Curve and Functional Outcomes - A Prospective Study
The aim of this prospective study is to evaluate the learning curve and functional outcomes of Thulium Fiber Laser Enucleation of the Prostate (TfLEP) performed by a single surgeon.
- Conditions
- Prostate Hyperplasia, Thulium Fiber Laser, Laser Prostate Enucleation
- Trial name
- ThuFLEP (NCT07349147)
- Testing
- Thulium Fiber Laser (TFL) Enucleation
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Muharrem Baturu
Endoscopic Sleeve Gastroplasty
Endoscopic Sleeve Gastroplasty for Morbid Obesity
Obesity and its related metabolic disorders are increasingly a heavy health burden to many parts of the world. Weight control is a well-known important step in avoiding type 2 diabetes mellitus (T2DM).
- Trial name
- NCT03124485
- Testing
- Endoscopic Sleeve Gastroplasty, Laparoscopic Sleeve Gastrectomy
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Chinese University of Hong Kong
Radial Head Fracture
Functional Outcomes After Radial Head Fractures Treated Non-operatively
The purpose of this study is to investigate the effects of physical therapy as part of the non-operative treatment of radial head fractures.There is currently no data to support the use of physical therapy in the non-operative…
- Trial name
- NCT03170128
- Testing
- Outpatient physical therapy in addition to standard follow-up visits, Home exercises in addition to standard follow-up visits
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- NYU Langone Health
Injury of Extensor Tendon of Hand, Tendon Adhesions
Evaluation of High-Purity Type I Collagen Biologic Wrap to Improve Function After Extensor Tendon Repair of the Hand
Tendon injuries of the hand, particularly extensor tendons, are prone to postoperative adhesions, extensor lag, and stiffness, leading to functional impairment.
- Trial name
- NCT07335653
- Testing
- High-Purity Type I Collagen (HPTC) Wrap, Standard Extensor Tendon Repair
- Where
- 2 sites in India
- Volunteers
- 60 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Intellectual Disability, Developmental Disability
Written Language Intervention for Adults With Intellectual and Developmental Disabilities
The purpose of this study is to evaluate the effects of a written language intervention using functional texts for young adults with intellectual and developmental disabilities.
- Trial name
- NCT05851937
- Testing
- Written language intervention
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Baylor University
Arthroscopic Surgery
Functional Outcomes After Hyaluronic Acid Injections Following Arthroscopy
The goal of this study is to investigate the effect of hyaluronic acid injection on functional recovery and pain control in patients following knee or shoulder arthroscopy.
- Trial name
- NCT07468045
- Testing
- CG Synovia (Hyaluronic Acid 0.5%)
- Where
- 2 sites in Indonesia
- Volunteers
- 9 people
- Sponsor
- Daewoong Group Indonesia
Depression - Major Depressive Disorder, Bipolar Disorder (BD)
Flumazenil for Benzodiazepine Reversal in Electroconvulsive Therapy
The goal of this study is to investigate whether administering flumazenil to reverse the effects of benzodiazepines and/or zopiclone during electroconvulsive therapy (ECT) can help reduce cognitive side effects without…
- Conditions
- Depression - Major Depressive Disorder, Bipolar Disorder (BD), Functional Magnetic Resonance Imaging (fMRI), Cognition
- Trial name
- FLEET (NCT07619092)
- Testing
- Flumazenil, Electroconvulsive therapy (ECT)
- Where
- Denmark
- Volunteers
- 145 people
- Sponsor
- Anders Jørgensen
Functional Movement Disorder
Digital Telerehabilitation in Functional Motor Disorders
Functional motor disorders (FMDs) are a broad spectrum of functional neurological disorders, including abnormal gait/balance disorders.
- Trial name
- NCT06274281
- Testing
- Digital Telerehabilitation, Usual care
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- Universita di Verona
Obesity, Liver Function
Obesity and Liver Function in Oesophageal Cancer
There is an established link between sarcopenia and outcomes in oesophageal cancer. There is scant reports in the literature regarding the influences of different obesity in different compartments.
- Trial name
- NCT04152044
- Testing
- Observation of different types of obesity and liver pathology in patients undergoing and oesophagectomy
- Where
- Ireland
- Volunteers
- 658 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Cardiovascular Disease, Type 2 Diabetes
Physical Health in Midlife: Influences of Adversity and Relationships Over Time
The purpose of this study is to determine the effects of individual characteristics, life stresses, and relationships over time on psychosocial outcomes (e.g. marriage, parenting, work) and physical health
- Trial name
- NCT01853332
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Beth Israel Deaconess Medical Center
Hypertension, Fall
Health Outcomes of Two Different Tai Chi Interventions
Tai Chi results in numerous health benefits but whether it can be tailored to elicit different health outcomes is not clear. Therefore, investigators compared the health benefits of two different Tai Chi interventions tailored…
- Trial name
- NCT04407403
- Testing
- Tai Chi tailored for lowering blood pressure (PRESSURE), Tai Chi tailored for improving balance (BALANCE)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Knee Osteoarthritis, Degenerative Joint Disease of the Knee
Patient Outcomes Following Kinematic and Functional Alignment in Robotic-Assisted Total Knee Arthroplasty With Randomized Insert Types
This study aims to evaluate patient outcomes following robotic-assisted total knee arthroplasty using the VELYS system. Patients undergoing surgery will receive either kinematic alignment or functional alignment as determined by…
- Trial name
- VELYS RCT (NCT07533188)
- Testing
- Medial Stabilized Insert, Cruciate Retaining Insert
- Where
- Singapore
- Volunteers
- 240 people
- Sponsor
- Singapore General Hospital
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