Clinical trials: Functional Status, open to volunteers
TBI (Traumatic Brain Injury), Status Epilepticus
Augmented Renal Clearance in Neurocritical Care
Stroke, severe brain injury, uncontrolled seizures and brain infections are the most common life-threatening neurological illnesses in the world with an estimated combined annual hospital management cost of up to 44 billion…
- Conditions
- TBI (Traumatic Brain Injury), Status Epilepticus, Bacterial Meningitis, Augmented Renal Clearance (ARC)
- Trial name
- Neuro-ARC (NCT07410624)
- Where
- 3 sites in United States, Canada
- Volunteers
- 512 people
- Sponsor
- University of Alberta
Body Composition, Cardiovascular Health
Differences in Ventilatory Function, Body Composition, and Cardiorrespiratory Fitness According to Training Status
The goal of this cross-over study is to evaluate the physiological response to exercise and body composition according to training status in participants with a wide spectrum of fitness states.
- Conditions
- Body Composition, Cardiovascular Health, Ventilatory Physiology
- Trial name
- NCT06246760
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 1,272 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Knee Osteoarthritis
Implementing a Group Physical Therapy Program for Veterans (GroupPT): Function QUERI 3.0
Implementing Group Physical Therapy for Veterans with Knee Osteoarthritis (Group PT): Function QUERI 3.0 aims to compare two implementation approaches for implementing Group PT in 20 VA facilities using a type III…
- Trial name
- GroupPT (NCT07215572)
- Testing
- Implementation Strategy: Foundational Arm, Implementation Strategy: REACH Arm
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Adequate Vitamin C Status, Inadequate Vitamin C Status
Anti-inflammatory Activities of Vitamin C Supplementation on the Gut Barrier Function in Adults With Obesity
This study is testing whether taking vitamin C every day can help improve gut health and reduce inflammation in adults with obesity.
- Trial name
- NCT07151105
- Testing
- Vitamin C Supplement + Low Vitamin C Diet
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Ohio State University
Thyroid Dysfunction, Hemodialysis
Evaluation of Thyroid Function, Lipid Profile, and Uric Acid Levels in Hemodialysis Patients
This observational study evaluates the prevalence and relationships of thyroid dysfunction, lipid abnormalities, and elevated uric acid levels in adult patients undergoing maintenance hemodialysis at Assiut University Hospital.
- Conditions
- Thyroid Dysfunction, Hemodialysis, Elevated Uric Acid
- Trial name
- NCT07157267
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy
Effects of High-Velocity Passive Stretch on Spasticity, Function, and Muscle Structure in Spastic CP Children
One of the traditional exercises applied to cerebral palsy (CP) is passive stretching exercises. Passive stretching exercises can be applied to these patients at various speeds.
- Conditions
- Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy
- Trial name
- NCT07007858
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
HFpEF, LVDD
Triple Combination Therapy (ARNI, SGLT2i, MRA) in Advanced HFpEF
Patients with advanced heart failure with preserved ejection fraction (HFpEF) will be randomly assigned in open-label multicenter study to receive triple combination therapy with [angiotensin receptor/neprilysin inhibitor [ARNI]…
- Conditions
- HFpEF, LVDD, Myocardial Fibrosis
- Trial name
- NCT06655480
- Testing
- [ARNI + SGLTi + AMR], [SGLTi + previously taken RAAS blocker]
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
Osteearthritis, Knee Arthritis, Osteoarthritis
Effects of Mobilized Balance Platform Exercises on Balance Parameters in Patients With Knee Osteoarthritis
This prospective single-blind randomized controlled study aims to investigate the effects of mobilized balance platform exercises on balance parameters, pain, functional status, fear of falling, and kinesiophobia in patients with…
- Trial name
- NCT07575425
- Testing
- Huber 360 Balance Training, Conventional Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Immune System, Stress
Impact of Peanut Consumption on Stress, Immune Function, Inflammation, and Cardiovascular Health in High-Stress Individuals
The purpose of this research is to determine whether peanut consumption improves indicators of cardiovascular disease (CVD) risk in human subjects following the consumption of study foods.
- Conditions
- Immune System, Stress, Chronic Stress, Cardiovascular Health
- Trial name
- NCT07735221
- Testing
- Peanuts, roasted, salted with skins, Isocaloric food
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Pregnancy, Postpartum
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior.
- Conditions
- Pregnancy, Postpartum, Childbirth, Health Status
- Trial name
- HIIT MAMA (NCT05009433)
- Testing
- High intensity interval training program for pregnant women, Moderate intensity continuous training program for pregnant women, Standard obstetric care with extended education on healthy lifestyle
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Hydration Status
Hydrate Heroes for Improving Brain Function & Mood
The primary goal of this 12-week randomized controlled study is to evaluate whether daily use of Hydrate Heroes results in measurable improvements in brain activity, mental health, and performance on cognitive tasks.
- Trial name
- NCT07241260
- Testing
- Hydrate Heroes (6 packets), Hydrate Heroes (3 packets)
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Quality of Lifte, Cystic Fibrosis (CF)
Characterisation of a Population of Adults Suffering From Cystic Fibrosis in a Belgian Reference Center
This research project aims to better understand the consequences of diabetes on the quality of life, respiratory function, and nutritional status of patients with cystic fibrosis followed at a Belgian reference center and to…
- Conditions
- Quality of Lifte, Cystic Fibrosis (CF), Diabetes
- Trial name
- NCT07442682
- Where
- Belgium
- Volunteers
- 162 people
- Sponsor
- Erasme University Hospital
Cervicogenic Dizziness
Sustained Natural Apophyseal Glides With and Without Facilitated Positional Release Technique in Cervicogenic Dizziness
Cervicogenic Dizziness is characterized by non-rotatory dizziness and a sense of disequilibrium associated with neck pain, stiffness, and decreased range of motion.
- Trial name
- NCT07646327
- Testing
- SNAGs with FRT, SNAGs
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Frailty, Sarcopenia
Comprehensive Geriatric Assessment in Adults Aged 40 Years and Older Living With HIV
People living with HIV are experiencing longer life expectancy due to effective antiretroviral therapy; however, they may develop age-related conditions earlier than the general population.
- Trial name
- HIV-AGE40 (NCT07453303)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Caregiver Stress, Caregiver Stress Syndrome
ACT Group for Family Caregivers of Stroke Survivors
The goal of this study is to evaluate the efficacy of group-based ACT intervention in improving the levels of psychological distress in caregivers of stroke survivors. The main questions it aims to answer are: 1.
- Conditions
- Caregiver Stress, Caregiver Stress Syndrome, Caregiver Burnout, Caregiver Distress
- Trial name
- NCT07528261
- Testing
- Group-based ACT Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Wright Institute
Cirrhosis, Liver, Splenectomy; Status
Effect of LSD on Renal Function in Cirrhosis Patients With Portal Hypertension Bleeding (2-Year Follow-Up)
Patients with liver cirrhosis often have impaired or at-risk kidney function due to the close link between liver and kidney (hepatorenal syndrome).
- Conditions
- Cirrhosis, Liver, Splenectomy; Status, Renal Function Abnormal, Portal Hypertension
- Trial name
- LSD-RFPH (NCT07585786)
- Volunteers
- 30 people
- Sponsor
- Northern Jiangsu People's Hospital
Bronchial Asthma, Vitamin D Deficiency
Vitamin D Status and Asthma Control, Pulmonary Function, and Oxidative Stress in Adults With Bronchial Asthma
Asthma is a chronic inflammatory airway disease associated with variable airflow limitation and persistent respiratory symptoms.
- Conditions
- Bronchial Asthma, Vitamin D Deficiency, Pulmonary Function Impairment, Oxidative Stress
- Trial name
- VD-ASTHMA (NCT07733635)
- Volunteers
- 134 people
- Sponsor
- Sinai University
Osteoarthritis, Hand Osteoarthritis
Balneotherapy and Peloid Therapy Impact Small Joint Diseases
This clinical trial investigates the effects of natural healing factors (mineral water and mud procedures) in combination with regular rehabilitation of patients with degenerative small joint disease.
- Conditions
- Osteoarthritis, Hand Osteoarthritis, Foot Osteoarthritis
- Trial name
- NCT06477393
- Testing
- Regular rehababilitation, Heat procedures, Healing mud application
- Where
- 2 sites in Lithuania
- Volunteers
- 130 people
- Sponsor
- Lithuanian University of Health Sciences
Fall, Daily Activities
Incidence and Factors of Functional Decline After Emergency Department Discharge in Older Adults With Falls
The goal of this observational study is to learn about changes in activities of daily living (ADL) in older adults after being discharged from the emergency department (ED) following a fall.
- Conditions
- Fall, Daily Activities, Functional Decline, Older Adults (65 Years and Older)
- Trial name
- FALL-ADL (NCT07163715)
- Volunteers
- 280 people
- Sponsor
- Ege University
Stroke, Hypoalbuminemia
Brief Title: The Role of Nutrition in the Rehabilitation of Patients With Eating Disorders After a Vascular Stroke.
Brief Summary: The main objective of this thesis is to investigate the role of nutrition - specifically the administration of protein supplements (single dose and double dose) - in the rehabilitation of stroke patients with low…
- Conditions
- Stroke, Hypoalbuminemia, Sarcopenia, Osteopenia
- Trial name
- Nutristroke (NCT06961825)
- Testing
- Dietary Supplement
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Ioannina