Clinical trials: Functional Test
Aortic Valve Stenosis, Aortic Valve Insufficiency
Von Willebrand Factor Point-of-care Testing to Improve Minimally Invasive TAVI Outcomes
Paravalvular regurgitation (PVR) is an important complication of Transcatheter Aortic Valve Implantation (TAVI) that is associated with a 2.5-fold increase risk of mortality.
- Trial name
- WITAVI-REAL (NCT03728049)
- Testing
- CT-ADP performed during TAVI procedure, No CT-ADP performed during TAVI procedure
- Where
- 9 sites in France
- Volunteers
- 944 people
- Sponsor
- University Hospital, Lille
Liver Metastases
Functional Liver After SBRT
In this study, the investigators aim to determine the dose-effect relationship between radiation dose and liver function by performing a hepatobiliary scintigraphy (HEBIS) before and after stereotactic body radiotherapy (SBRT)…
- Trial name
- FAFOR (NCT07033364)
- Testing
- Functional liver imaging using hepatobiliary scintigraphy (HEBIS)
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- The Netherlands Cancer Institute
Stable Angina Pectoris
Evaluation and Comparison of Several Point-of-care Platelet Function Tests in Predicting Clinical Outcomes in Clopidogrel Pre-treated Patients Undergoing Elective PCI.
The purpose of this study is to investigate whether the level of Platelet Inhibition as assessed with five point-of-care platelet function assays correlates with clinical (periprocedural) outcomes such as Acute Myocardial…
- Trial name
- NCT00352014
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- R&D Cardiologie
Obstructive Ventilation Disorders
Effect of Bronchodilatator Testing on Multiple-breath-washout (MBW) Derived Lung Function Parameters
The investigators aim to evaluate the effect of bronchodilatator testing on multiple-breath-washout derived lung function parameters.
- Trial name
- NCT02826226
- Testing
- multiple-breath-washout test, Bronchodilator Agents
- Where
- Germany
- Volunteers
- 145 people
- Sponsor
- Universitätsmedizin Mannheim
Attention Deficit Disorder With Hyperactivity (ADHD), Attention Deficit Disorder (ADD)
A Quick and Reliable Eye Movement Test to Help Diagnose ADHD in Children.
Attention Deficit Hyperactivity Disorder (ADHD) affects more than 5 % of children and adolescents, with a globally increasing prevalence.
- Trial name
- ADHDin15? (NCT07136259)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Onovis Augenpraxis
Breast Cancer, FIT-HaNSA
The Validity and Reliability of FIT-HaNSA in Breast Cancer Patients
Breast cancer is the most common type of cancer among women and covers 25% of all cancers. After mastectomy and reconstruction, many patients develop various upper extremity complications such as joint movement limitation, pain…
- Conditions
- Breast Cancer, FIT-HaNSA, Upper Extremity Dysfunction
- Trial name
- NCT04795778
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Platelet Function Tests, Thrombin Generation Tests
Point-of-care Assessment of Thrombin Generation and Platelet Function in Children Requiring Cardiopulmonary Bypass
Coagulopathy after cardiopulmonary bypass (CPB) is associated with increased morbidity and mortality. Clot formation and clot stability are important factors in coagulation and hemostasis.
- Conditions
- Platelet Function Tests, Thrombin Generation Tests, Perioperative Coagulopathy
- Trial name
- NCT02833025
- Testing
- Thrombin generation and Platelet Function Testing
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- The Hospital for Sick Children
Stroke, Motor Disorders
BCI-assisted MI Intervention in Subacute Stroke
Stroke is a leading cause of long-term disability. Cost-effective post-stroke rehabilitation programs are critically needed. Brain-Computer Interface (BCI) systems which enable the modulation of EEG sensorimotor rhythms are…
- Trial name
- Promotoer (NCT04353297)
- Testing
- EEG-based BCI system for (hand) Motor Imagery training, Motor Imagery training
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Anterior Cruciate Ligament Rupture
Efficacy of Preoperative Re-education on Patients With an Anterior Cruciate Ligament Rupture
Anterior cruciate ligament (ACR) rupture is a common lesion of sportsmen that leads to functional deficits which are difficult to overcome.
- Trial name
- PRELIG (NCT02505659)
- Testing
- Preoperative re-education
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Health Young Individuals
The Immediate Effect of Manual Therapy Application on Respiratory Functions in Healthy Young Individuals
Manual therapy techniques targeting the thoracic region are commonly used in clinical practice. It has been suggested that manual therapy interventions directed at the spine can increase mobility of the spine and chest wall…
- Trial name
- NCT05934240
- Testing
- Manual therapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Pancreatic Cancer
Secretin-enhanced Magnetic Resonance Cholangiopancreatography (S-MRCP) and Pancreatic Function Following Surgery
The aim of this study will be to determine whether secretin-enhanced MRCP (S-MRCP) as well as traditional magnetic resonance imaging (MRI) of the pancreas will allow the investigators to quantify the pancreas' ability to secrete…
- Trial name
- NCT01094535
- Testing
- Synthetic Human Secretin
- Where
- United States
- Sponsor
- Columbia University
Subjects With an Existing Intra-arterial Line
Pulse Oximetry_Performance Testing- PCBA-1 (Printed Circuit Board Assembly) NEO/PEDS
To determine accuracy specifications of the pulse oximeter in the NEO/PEDS subject population
- Trial name
- NCT01797250
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Healthy Japanese Individuals
Verification Study of the Effects of Consumption of the Test Food on the Musculoskeletal System
The goal of this clinical trial is to test the effects of the test products on the locomotor system in healthy Japanese adults with low muscle mass and knee joint discomfort.
- Trial name
- NCT07729657
- Testing
- Food containing NAG and HA, Food containing NAG
- Where
- 2 sites in Japan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bloomage Biotechnology Corp., Ltd.
Intestinal Permeability, Challenge Test
Intestinal Barrier Function and Probiotics.
Rationale: Enterotoxigenic Escherichia coli (ETEC) bacteria adhere to the mucosa of the proximal intestines. There it produces an toxin which presents a local and relevant challenge to the intestines.
- Conditions
- Intestinal Permeability, Challenge Test, Intestinal Health, Inflammation
- Trial name
- NCT01241201
- Testing
- Priobiotic supplement VSL#3
- Where
- Netherlands
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- TNO
Healthy Subjects
Y-Balance Test Training for Ankle Function and Lower Limb Functional Performance
This randomized controlled study investigated whether a 6-week home-based training program based on the Y-Balance Test could improve ankle function and lower limb functional performance in university students.
- Trial name
- NCT07826312
- Testing
- Y-Balance Test-Based Training Program
- Where
- Portugal
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Chronic Obstructive Pulmonary Disease
Functional Tests in Individuals With Chronic Obstructive Pulmonary Disease (COPD)
Objectives: to evaluate and compare the responses to the various functional tests, and the concordance between the six-minute walk test in hallway (6MWT) and the of oval track (6MWToT), of treadmill (6MWTT), and of treadmill with…
- Trial name
- NCT00660738
- Where
- Brazil
- Volunteers
- 11 people
- Sponsor
- Universidade Federal de Sao Carlos
Type1 Diabetes Mellitus
Comparison of Motor and Sensory Functions of the Hand in Children With Type 1 Diabetes Mellitus and Their Healthy Peers
Type 1 Diabetes Mellitus (T1DM) is a condition where the body cannot produce a hormone called insulin. Although it is commonly seen in children and young people, it can occur at any age.
- Trial name
- NCT06206317
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Erdal AYDIN
Healthy Aging, Physical Fitness
Effects of Core Stability Training Using Pilates on Core Muscle Strength, Pulmonary Function, and Cardio-respiratory Fitness in the Elderly.
This study investigates how different types of exercise-specifically Mat Pilates and Aerobic training-can help improve the physical health and breathing capacity of healthy older adults aged 60 to 77.
- Conditions
- Healthy Aging, Physical Fitness, Core Stability, Respiratory Function
- Trial name
- PLT-AER-ELD (NCT07470060)
- Testing
- Mat Pilates Program, Aerobic Exercise (Treadmill Walking)
- Where
- Thailand
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Walailak University
Bipolar Depression
Magnetic Resonance Imaging Study of Lisdexamfetamine for Bipolar Depression
There have been reports that stimulants may be effective for bipolar depression without triggering mania. This study will examine whether lisdexamfetamine can improve depressive symptoms over the course of eight weeks.
- Trial name
- NCT01051440
- Testing
- Lisdexamfetamine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Hereditary Angioedema
Social Evaluated Cold Pressor Test in Hereditary Angioedema Patients
This study aims to evaluate the differences in objective and subjective stress responses between patients with hereditary angioedema and healthy individuals to a stress-induced challenge like socially-evaluated cold pressure…
- Trial name
- FROSEN (NCT06414252)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA