Clinical trials: Functioning, Psychosocial
Adverse Childhood Experiences
The FACE Self-help App for Fostering Resilience
The FACE self-help app is an online intervention for young adults with Adverse Childhood Experiences (ACEs). It was developed based on well-established cognitive-behavioural therapy principles.
- Trial name
- NCT05824182
- Testing
- FACE self-help App
- Where
- Switzerland
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Jeannette Brodbeck
Cognitive Ability, General, Psychiatric and/or Mood Disorders
The Bucharest Early Intervention Project
The purpose of this study is to determine the long term effects of early intervention (placement into foster care) on physical, cognitive, social and brain development and psychiatric symptomatology in previously…
- Conditions
- Cognitive Ability, General, Psychiatric and/or Mood Disorders, Brain Function, Social Cognition
- Trial name
- BEIP (NCT00747396)
- Testing
- Foster Care Placement
- Where
- Romania
- Volunteers
- 136 people
- Sponsor
- Charles Alexander Nelson III
Schizophrenia, Schizoaffective Disorder
The Effects of tDCS on Auditory Hallucination, Insight, Neurocognitive Function and HRV in Patients With Schizophrenia
The study aimed to investigate whether transcranial direct current stimulation could modify auditory hallucination, insight, neurocognitive function, heart rate variability, psychosocial functioning and quality of life in…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Auditory Hallucination, Verbal, Neurocognitive Dysfunction
- Trial name
- NCT03388554
- Testing
- tDCS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Inflammatory Bowel Diseases
Group Cognitive Behavioral Therapy for IBD Patients
Inflammatory bowel disease (IBD) patients commonly suffer from disturbed psychosocial functioning and poor quality of life compared to other chronic disease patients.
- Trial name
- NCT03667586
- Testing
- Group cognitive behavioral therapy
- Where
- Greece
- Volunteers
- 79 people
- Sponsor
- University Hospital of Patras
Acute Orthopedic Injury
Toolkit for Optimal Recovery After Orthopedic Injury
This is a multi-site randomized feasibility trial of the Toolkit for Optimal Recovery after Orthopedic Injury (TOR), a mind-body program to prevent persistent pain and disability in at-risk patients with acute orthopedic injury…
- Trial name
- TOR (NCT04973696)
- Testing
- Toolkit for Optimal Recovery after Orthopedic Injury, Minimally Enhanced Usual Care (MEUC)
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Massachusetts General Hospital
Anxiety, Self-Efficacy
Musically-Guided Paced Breathing Improves Mental Health in War-Affected Adolescents
Examine the impact of a mindfulness condition, a guided paced breathing audiovisual intervention condition, and a guided paced breathing audiovisual intervention plus take-home application condition compared to a matched control…
- Conditions
- Anxiety, Self-Efficacy, Depression Not Otherwise Specified
- Trial name
- NCT06988800
- Testing
- Paced breathing wellness breathing sessions, Mindfulness video sessions
- Where
- Palestinian Territories
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Muvik Labs
Graves Ophthalmopathy
Analysis Between the Results of Two Surgical Techniques of Orbital Decompression in Patients With Graves Orbitopathy
Randomized prospective clinical trial, aiming to compare two techniques of orbital decompression. Patients with Graves orbitopathy in the inactive phase for at least 6 months will be divided in two groups; one group will be…
- Trial name
- NCT03278964
- Testing
- Orbital decompression
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- University of Sao Paulo General Hospital
Schizophrenia
A Study in Italy About Evidence Based Psychosocial/Rehabilitative Interventions in Patients With Early Schizophrenia Treated Continuously With Antipsychotics
This is a prospective, observational, naturalistic study conducted according to Italian law. The Investigators are interested in observing how often Evidence Based (EB) psychosocial and rehabilitative interventions are actually…
- Trial name
- ESCHILO (NCT03693794)
- Where
- Italy
- Volunteers
- 270 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Stem Cell Transplant During Childhood, Allogeneic Bone Marrow Transplant During Childhood
Cognitive, Academic and Psychosocial Functioning in Long-Term Survivors of Pediatric Stem Cell Transplantation
This is an observational study to collect information by use of performance-based measures and survey questionnaires. It does not include interventions aimed at altering patient outcome.
- Trial name
- NCT01701492
- Testing
- Questionnaire, Neurocognitive Evaluation
- Where
- United States
- Volunteers
- 133 people
- Sponsor
- St. Jude Children's Research Hospital
Substance Abuse, Substance Dependence
fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults
The purpose of this study is to determine whether drug-dependent adults who participate in a dual processing relapse prevention treatment protocol that allows for sensory-based exposure experiences over 10-weeks in outpatient…
- Conditions
- Substance Abuse, Substance Dependence, Alcohol Abuse, Drug Use
- Trial name
- NCT01320748
- Testing
- Dual Processing, Relapse Prevention
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Inova Health Care Services
PTSD, Functioning, Psychosocial
What Difficulties Do Children and Adolescents Experience in Everyday Activities After a Traumatic Event? Focus Groups and Delphi Survey for the Development of a Questionnaire on PTSD-related Functional Impairment
Post-traumatic Stress Disorder (PTSD) in children and adolescents is often associated with a myriad of significant impairments in daily functioning, including family relationships, school/work, leisure time activities, and social…
- Trial name
- NCT05984706
- Testing
- Focus groups and Delphi Questionnaire
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Children's Hospital, Zurich
Hearing Loss, Age-Related, Speech Intelligibility
Benefits of Choir for Older Adults With Unaddressed Hearing Loss (WP2)
Unaddressed age-related hearing loss is highly prevalent among older adults, typified by negative consequences for speech-in-noise perception and psychosocial wellbeing.
- Conditions
- Hearing Loss, Age-Related, Speech Intelligibility, Psychosocial Functioning
- Trial name
- NCT06580847
- Testing
- Group Singing, Audiobook Club
- Where
- 7 sites in United States, Australia and 3 more
- Volunteers
- 210 people
- Sponsor
- Toronto Metropolitan University
Stress Disorders, Post-Traumatic, Depressive Disorder
Whole Health in VA Mental Health: Omnis Salutis
Recent Veterans of the Afghanistan and Iraq conflicts are presenting in VA care with high rates of posttraumatic stress disorder (PTSD), depression, anxiety, and substance use disorders.
- Conditions
- Stress Disorders, Post-Traumatic, Depressive Disorder, Anxiety Disorders, Substance-Related Disorders
- Trial name
- OS RCT (NCT05400252)
- Testing
- Omnis Salutis, Health and Wellness
- Where
- 2 sites in United States
- Volunteers
- 238 people
- Sponsor
- VA Office of Research and Development
Psychosocial Functioning, Mindfulness
Psychosocial Effects of Mindfulness-Based Exercise in Postmenopausal Women
Menopause is a natural biological process characterized by the permanent cessation of the menstrual cycle in women. Hormonal changes associated with menopause commonly lead to mood swings, anxiety, depression, stress, and…
- Conditions
- Psychosocial Functioning, Mindfulness, Postmenopausal Symptoms
- Trial name
- NCT07424521
- Testing
- Mindfulness-Based Stress Reduction Training
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Halic University
Haemophilia
Multidisciplinary Evaluation of Patients With Hemophilia
Multidisciplinary assessment of the physical, functional and psychosocial alterations in patients with hemophilia around the country.
- Trial name
- HOLISTIC (NCT02198430)
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Universidad de Murcia
Mild Traumatic Brain Injury
Cognitive and Psychosocial Outcome After Mild Traumatic Brain Injury
Patients with traumatic brain injury are likely to present with cognitive, psychological, emotional and behavioral problems during different periods, all of which affect patients' life quality seriously.
- Trial name
- NCT02161172
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Shanghai 6th People's Hospital
Breast Cancer
Study of the Effects of Chemotherapy on Memory and Other Mental Functions in Women With Breast Cancer
Many breast cancer patients treated with chemotherapy complain of problems with concentration and memory. This has been referred to as chemo fog.
- Trial name
- NCT00260975
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Type 1 Diabetes Mellitus
Psychosocial Functioning in Young Adults With Type 1 Diabetes
Background: The often studied psychosocial correlates that relate to health outcomes in adolescents with Type 1 Diabetes (T1D) are factors such as self-efficacy, depression, distress, quality of life, and adherence.
- Trial name
- NCT02874612
- Testing
- Psychosocial Survey Questionnaires
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Adverse Childhood Experience, Endothelial Function (FMD)
Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity
Adverse childhood experiences (ACEs) represent highly stressful events in the first 18 years of life that include abuse, neglect, and household and community-level dysfunction.
- Conditions
- Adverse Childhood Experience, Endothelial Function (FMD), Endothelial Injury, Mitochondrial Function
- Trial name
- PROMISE (NCT07244809)
- Testing
- Mitoquinone mesylate (MitoQ)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Pain, Osteoarthritis
Psychosocial Factors a Prognostic Study of Pain in Patients With CMC Osteoarthritis
In this clinical trial, females with a diagnosis of thumb CMC OA, will be recruited. The primary outcome of potential risk factors of osteoarthritis, pain and function will be measured using the demographic data, visual analog…
- Trial name
- CMC (NCT03821298)
- Testing
- Standard of Care Hand Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Gannon University