Clinical trials: Fungal Skin Infection, open to volunteers
Onychomycosis
Fractional CO₂ Laser or 40% Urea With Topical Fluconazole Microemulsion in Onychomycosis
To evaluate the efficacy and safety of topical fluconazole microemulsion enhanced by fractional CO₂ laser versus by 40% urea ablation in treatment of Onychomycosis.
- Trial name
- NCT07033962
- Testing
- "Fractional CO2 laser" and "topical fluconazole microemulsion", "Urea 40%" and "topical fluconazole microemulsion"
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Skin and Connective Tissue Diseases, Neglected Tropical Diseases
Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health Workers
Skin-related Neglected Tropical Diseases (Skin NTDs) affect about 1.8 billion people worldwide, particularly in poor and rural communities where healthcare access is limited.
- Conditions
- Skin and Connective Tissue Diseases, Neglected Tropical Diseases, Leprosy, Buruli Ulcer
- Trial name
- SkincAIr (NCT07506967)
- Testing
- A mobile app with AI functionality for diagnosing skin-related NTDs
- Where
- 5 sites in Democratic Republic of the Congo, Ethiopia and 3 more
- Volunteers
- 2,420 people
- Sponsor
- Kenya Medical Research Institute
Dermatophyte Infection
Fungal Resistance in Dermatophyte Infection
The aim of the study is to compare the efficiency of broth microdilution versus disk diffusion method for antifungal drug susceptibility testing of the most used drugs in dermatophytosis treatment.
- Trial name
- NCT06729216
- Testing
- Antifungal susceptibility testing (AFST)
- Volunteers
- 42 people
- Sponsor
- Cairo University
Tinea Pedis
A Phase 1b Study of ZYG24004 in Participants With Tinea Pedis Caused by Dermatophytes
This is a multicenter, randomized, double-blind, placebo-controlled Phase 1b study in adult participants with tinea pedis caused by dermatophytes.
- Trial name
- NCT07668999
- Testing
- ZYG24004 1% topical film-forming formulation, ZYG24004 3% topical film-forming formulation
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Sinomune Pharmaceutical Co., Ltd
Pityriasis Versicolor
Comparison of the Efficacy of Topical Luliconazole 2% Cream vs Topical Ketoconazole 1% Cream in the Treatment of Pityriasis Versicolor.
Pityriasis versicolor is a common superficial fungal infection caused by Malassezia species, characterized by hypo- or hyper-pigmented scaly patches on the skin. Topical antifungal agents are the mainstay of treatment.
- Trial name
- P versicolor (NCT07333170)
- Testing
- Luliconazole Cream 1%, Topical ketoconazole 2% cream
- Volunteers
- 86 people
- Sponsor
- PAEC General Hospital, Islamabad
Onychomycosis
Isotretinoin Versus Excimer Light an Adjuvant in Treating Onychomycosis
3 groups of patients with onychomycosis will be recruited. Group A will receive itraconazole alone. Group B will receive itraconazole + low dose isotretinoin and group C will be treated with itraconazole + excimer light sessions.
- Trial name
- NCT06485505
- Testing
- ISOtretinoin 10 MG, excimer light, Itraconazole 200 mg
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Zagazig University
Tinea Pedis
Efficacy of Tropical Sertaconazole Nitrate 2% Vs Clotrimazole 1% for Tinea Pedis
This randomized controlled trail study will be carried out on OPD patients in the Department of Dermatology, Jinnah Postgraduate Medical Center.
- Trial name
- NCT06869681
- Testing
- Topical Sertaconazole 2%, Clotrimazole 1%
- Volunteers
- 100 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Onychomycosis of Toenail
Safety and Efficacy of Next Science Gel on Toenail Fungus
This is a 52 week, 20-patient open-label pilot study on the safety and efficacy of Next Science Wound gel in the treatment of mild to moderate Distal Subungual Onychomycosis.
- Trial name
- NCT04042857
- Testing
- Next Science Treatment Gel
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Next Science TM
Tinea Corporis
Comparison of Itraconazole With Itraconazole and Isotretinoin in the Treatment Duration, Safety a n d Cure Rate in Adult Patients of Tinea Corporis/ Cruris-A Randomised Controlled Trail
Tinea corporis and tinea cruris are common superficial fungal infections that have become increasingly difficult to treat because of prolonged disease duration, frequent recurrences, and suboptimal response to standard antifungal…
- Trial name
- NCT07675239
- Testing
- Itraconazole (200 mg), ISOtretinoin 20 MG
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Pak Emirates Military Hospital
Onychomycosis of Toenail
URGO MICKAEL Filmogel, Topical Treatment of Onychomycosis
The objective of this clinical study is to evaluate the performance of URGO MICKAEL Filmogel as a topical treatment for mild to moderate onychomycosis
- Trial name
- MICKAEL (NCT07828184)
- Testing
- URGO MICKAEL Filmogel
- Where
- France
- Volunteers
- 54 people
- Sponsor
- CEN Biotech
Tinea Pedis
Topical Tolnaftate Stick for Tinea Pedis: An Open-Label Interventional Study
This study is designed to evaluate the safety and effectiveness of multiple 1% tolnaftate formulations delivered through novel stick-based vehicles in individuals with tinea pedis (athlete's foot).
- Trial name
- NCT07245667
- Testing
- 1% Tolnaftate Stick Formula A, 1% Tolnaftate Stick Formula B, 1% Tolnaftate Stick Formula C
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Propedix, Inc.
Pneumonia, Pneumocystis, Autoimmune Inflammatory Rheumatic Disease
Efficacy and Safety of Prophylactic Treatment for Pneumocystis Jirovecii Pneumonia in Patients With Autoimmune Inflammatory Rheumatic Disease
This is an open-labeled, prospective clinical study aims at collecting and analyzing baseline characteristics of autoimmune inflammatory rheumatic disease (AIIRD) patients receiving sulfanilamide for preventive purposes, as well…
- Conditions
- Pneumonia, Pneumocystis, Autoimmune Inflammatory Rheumatic Disease, Autoimmune Diseases, Connective Tissue Disease
- Trial name
- NCT06499233
- Testing
- Trimethoprim/Sulfamethoxazole
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Tongji Hospital
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Tinea Versicolor, Pityriasis Versicolor
A Study of the Clinical Efficacy and Safety of 20% Cassia Alata Extract Against Tinea Versicolor
The goal of this clinical trial is to establish the efficacy of Cassia alata extract as a cream form in treating tinea versicolor (liver spots/shifting clouds).
- Trial name
- NCT05730244
- Testing
- 20% Cassia alata cream
- Where
- Jamaica
- Volunteers
- 20 people
- Sponsor
- The University of The West Indies
Dermatophyte Infection
Role of Oral Voriconazole in the Treatment of Resistant Dermatophyte Infections
Treatment of dermatophyte infection in our country (Pakistan) is becoming difficult due to the developing resistance to traditional antifungal agents.
- Trial name
- NCT06680544
- Testing
- Voriconazole high dose, Voriconazole low dose
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Sheikh Zayed Medical College
Pityriasis Versicolor
Mycological Efficacy and Safety of Ketoconazole 2% Shampoo With a Seven-Day Versus Three-Day Treatment Duration in Pityriasis Versicolor
The goal of this clinical study is to find out whether using ketoconazole 2% shampoo for seven days works better than using it for three days in treating pityriasis versicolor.
- Trial name
- NCT07471178
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Fakultas Kedokteran Universitas Indonesia
Diet Habit, Body Weight
Sports Nutrition Assessment Program
The NutriEvalUA program is an observational study aiming to assess the nutritional status, body composition, hydration, physical activity, and health indicators in university athletes.
- Conditions
- Diet Habit, Body Weight, Athlete Foot
- Trial name
- NutriEvalUA (NCT07104669)
- Testing
- diet, Physical activity, body composition
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Fusariosis
Markers of Infection and Resistance in Invasive Fusariosis
In recent decades, invasive fusarioses have been emerging fungal pathologies with high mortality. The prognosis depends on the speed of the diagnosis, but currently biological diagnosis is mainly based on fungal culture, no…
- Trial name
- FUSIMIR (NCT04937751)
- Testing
- biomarkers
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Chronic Mucocutaneous Candidiasis, Invasive Aspergillosis
Natural History of Individuals With Immune System Problems That Lead to Fungal Infections
Background: The immune system is made up of special cells, tissues, and organs that fight infections. Problems with this system may lead to frequent, severe, or unusual fungal infections.
- Conditions
- Chronic Mucocutaneous Candidiasis, Invasive Aspergillosis, CARD9, APECED
- Trial name
- NCT01386437
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Fungal Infection by Site, Tinea Capitis
Clinical, Dermoscopic, and Mycological Characteristics of Tinea Capitis in Children
Tinea capitis is a common dermatophyte infection of the scalp in children aged 0-9 years .The prevalence of tinea capitis in Egypt is 0.4% and higher in public than private schools, Boys were more affected than girls according to…
- Trial name
- NCT07802600
- Testing
- Dermoscopic examination: the findings are divided into pathognomic and non-specific signs, Direct Microscopy (KOH) examination, Fungal culture:
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University