Clinical trials: Furcation Defects
Furcation Defects
Platelet Rich Fibrin+1% Alendronate in Treatment of Mandibular Degree II Furcation Defects
The present study was designed to evaluate the combined efficacy of PRF and 1% ALN in the treatment of mandibular degree II furcation defects when compared with PRF and open flap debridement (OFD) alone.
- Trial name
- NCT02609061
- Testing
- Open flap debridement (OFD), OFD with Platelet rich fibrin (PRF), OFD with Platelet rich fibrin (PRF)+1% Alendronate (Drug) in gel form
- Where
- India
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Furcation Defects
Evaluate the Effect of Hyaluronic Acid in the Treatment of Furcation Involvement
the effect Hyaluronic Acid in the Treatment of Furcation Involvement
- Trial name
- NCT04851548
- Testing
- hyaluronic acid
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Furcation Defects, Periodontitis
Treatment of Advanced Grade III Periodontal Furcation Lesions
Periodontitis, a microbially-driven inflammatory disease has been shown to be the sixth most common disease of mankind. The 2009 UK Adult Dental Health Survey found that 54% of adults experience gum bleeding (gingivitis) with 45%…
- Conditions
- Furcation Defects, Periodontitis, Surgical Procedure, Unspecified, Periodontal Bone Loss
- Trial name
- NCT05237739
- Testing
- Non-Surgical Periodontal treatment (NSPT), Open Flap Debridement (OFD)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- King's College London
Furcation Defects, Periodontitis
Non-surgical vs. Surgical Therapy for Periodontal Furcations
Periodontitis is an inflammatory disease of the tooth-supporting apparatus, which leads to attachment and bone loss and eventually to tooth loss if treatment is not provided.
- Conditions
- Furcation Defects, Periodontitis, Surgical Procedure, Unspecified
- Trial name
- NCT05237401
- Testing
- Non-Surgical Periodontal treatment (NSPT), Surgical Periodontal treatment/ Open Flap Debridement (OFD)
- Where
- United Kingdom
- Volunteers
- 59 people
- Sponsor
- King's College London
Periodontitis, Furcation Defects
Vital Root-resective Therapy in Furcation-involved Maxillary Molars
The primary aim of this study is to evaluate 1-year survival of maxillary molars with subclass C vertical furcation involvement after vital root resective therapy
- Trial name
- NCT05259982
- Testing
- Vital root resection
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- University of Santiago de Compostela
Furcation Defects
Platelet Rich Fibrin+1.2% Atorvastatin in Treatment of Mandibular Degree II Furcation Defects
The present study was designed to explore the effectiveness of PRF combined with 1.2% ATV gel in treatment of mandibular degree II furcation defects in comparison to PRF and open flap debridement (OFD) alone.
- Trial name
- NCT02612792
- Testing
- Open flap debridement (OFD), OFD with Platelet rich fibrin (PRF), OFD with Platelet rich fibrin (PRF)+1.2% Atorvastatin (Drug) in gel form
- Where
- India
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Furcation Defects, Periodontal Diseases
Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade III Furcation Defects (FURC-III-OST)
Teeth with furcation grade III defects will be treated with open flap debridement, with or without osteoplasty. The study is designed to examine the effect of osteoplasty in the treatment of teeth with furcation grade III defects…
- Trial name
- FURC-III-OST (NCT04017429)
- Testing
- Open flap debridement with osteoplasty, Open flap debridement without osteoplasty
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oslo
Injectable Platelet-Rich Fibrin, Minimally Invasive
Injectable Platelet-Rich Fibrin With Minimally Invasive Non-Surgical Technique in Treatment of Grade II Furcation Defects
This study aims to compare the clinical and radiographic effectiveness of injectable platelet-rich fibrin (i-PRF) combined with minimally invasive non-surgical therapy (MINST) versus MINST alone in the management of class II…
- Conditions
- Injectable Platelet-Rich Fibrin, Minimally Invasive, Non-Surgical Technique, Grade II Furcation Defects
- Trial name
- NCT07787949
- Testing
- Minimally invasive non-surgical technique (MINST), Minimally invasive non-surgical technique (MINST) + injectable platelet-rich fibrin (i-PRF) injection
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Furcation Defects
Comparison of Platelet Rich Fibrin as Graft & Membrane Vs Hyaluronic Acid & Amniotic Membrane in the Treatment of Interradicular Defects
This study is intended to compare the efficacy of platelet-rich fibrin as a graft and a membrane versus hyaluronic acid(Gengigel) and amniotic membrane in the treatment of mandibular grade II furcation defects.
- Trial name
- CPRFGMHATID (NCT03578744)
- Testing
- Conventional Flap surgery
- Where
- India
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Periodontal Disease
EMD and/or Bone Substitute for the Treatment of Class II Furcations
To clinically evaluate the treatment of mandibular class II furcation defects with enamel matrix derivative (EMD) and/or a bone substitute graft make of beta tricalcium phosphate/hydroxyapatite (βTCP/HA).
- Trial name
- NCT02474498
- Testing
- EMD, βTCP/HA, Flap access surgery
- Where
- Brazil
- Volunteers
- 41 people
- Sponsor
- University of Campinas, Brazil
Furcation Defects
Piezosurgery in the Treatment of Class II Furcation Involvement
The purpose of this study is to evaluate the effectiveness of piezosurgery in the treatment of class II furcation involvement using biomaterials and new surgical techniques
- Trial name
- NCT02132806
- Testing
- Piezosurgery with biomaterial mp3 + bracket, Piezosurgery with biomaterial mp3, Piezosurgery
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Matteo Visintin
Furcation Defects
Surgical Treatment of Mandibular Furcations Using a Xenograft With/Without a Collagen Membrane
The aim of the study was to perform a randomized controlled clinical study in order to compare the effects of a bovine derived xenograft (with 10% collagen) + a bioabsorbable membrane (control group, CG) vs a bovine derived…
- Trial name
- NCT03354182
- Testing
- Open flap surgery, Bio-oss collagen, Bio-gide
- Volunteers
- 19 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Chronic Periodontitis
Local Host Modulating Agents Alendronate & Aloe Vera for Treatment of Furcation Defects in Chronic Periodontitis
Alendronate (ALN), commonly use bisphosphonates is proposed to have osteostimulative properties in vivo and in vitro, as shown by an increase in the matrix formation, and acts as a potent inhibitor of bone resorption.
- Trial name
- NCT03204097
- Testing
- Alendronate, Aloe Vera
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Periodontitis, Periodontitis (Stage 3)
Morphological Characteristics of Mandibular Molar Furcation Involvement and Efficacy of Regenerative Surgical Treatment
This study consists of two components evaluating furcation involvement in mandibular molars among Stage III or Stage IV periodontitis patients.
- Conditions
- Periodontitis, Periodontitis (Stage 3), Furcation Defects
- Trial name
- NCT07770256
- Testing
- Acellular Dermal Matrix + EMD + Xenograft, Autogenous Connective Tissue Graft + EMD + Xenograft
- Where
- Vietnam
- Volunteers
- 98 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City