Clinical trials: GFR
Chronic Kidney Disease Stage 3A, Chronic Kidney Disease Stage 3B
Combined Versus Multicomponent Training in People With Chronic Kidney Disease Stages 3a and 3b
This randomized controlled trial will compare the effects of 12 weeks of combined training (aerobic plus resistance exercise) and multicomponent training (aerobic plus resistance plus balance exercise) with a control group…
- Conditions
- Chronic Kidney Disease Stage 3A, Chronic Kidney Disease Stage 3B, Chronic Kidney Disease, Non-dialysis
- Trial name
- NCT07901621
- Testing
- Combined Training, Multicomponent Training
- Where
- Brazil
- Volunteers
- 57 people
- Sponsor
- University of Brasilia
Kidney Function Issue, Diagnosis
Method VALIDation and Evaluation of Non-radioactive Methods to Measure Glomerular Filtration Rate
This study is a single centre intervention study to compare two methods of determining the measured glomerular filtration rate (mGFR).
- Conditions
- Kidney Function Issue, Diagnosis, Chronic Kidney Diseases
- Trial name
- VALIDGFR (NCT06259422)
- Testing
- Iohexol, 125I-iothalamate and 131I-hippuran
- Where
- Netherlands
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Kidney Transplantation
The Long-term Effect of Marine Omega-3 Fatty Acid Supplementation in Renal Transplantation
This is a long-term intervention study on the effects of marine n-3 PUFAs in renal transplantation. Our hypothesis is that patients treated with marine n-3 PUFA supplementation will have less decline in kidney transplant function…
- Trial name
- EMiRA (NCT03018041)
- Testing
- Omacor
- Where
- 6 sites in Norway
- Volunteers
- 174 people
- Sponsor
- Joe Chan
Other Impaired Renal Function Disorder
Effects of THW and rhTSH in Glomerular Filtration Rate During RIT
To observe the influence of thyroid hormone withdrawal and of recombinant human TSH during radioiodine therapy in renal function.
- Trial name
- NCT01945125
- Testing
- rhTSH Group
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Autosomal Dominant Polycystic Kidney
Outcome of ADPKD With Octreotide LAR
In this observational, retrospective study we will primarily aim at evaluating the independent role of baseline clinical and laboratory parameters, including TKV, in the prediction of long term chronic GFR decline and other…
- Trial name
- ADPKD648 (NCT06193616)
- Testing
- Octreotide
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Chronic Kidney Failure
Furosemide and Creatinine Tubular Stress Test in Order to Measure Proximal Tubule Residual Function
This is a two phase study. The first part will take place at the National Institute of Cardiology in Mexico, the second phase will be made in collaboration with the University of California San Diego and University of Minnesota.
- Trial name
- NCT05105009
- Testing
- Furosemide Injection, Creatinine Powder, Iohexol
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Glomerular Filtration Rate
Evaluation of Protein Loading on Measurement of Renal Reserve
The goal of this clinical trial is to evaluate the effect of protein loading on the measurement of renal reserve using the MediBeacon Transdermal glomerular filtration rate (tGFR) system.
- Trial name
- NCT07335614
- Testing
- Lumitrace, MediBeacon Transdermal Glomerular Filtration Rate Measurement System (TGFR)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- MediBeacon
Hepatitis C
Ribavirin Bioavailability After Telaprevir Exposure
Anemia is more frequent in patients receiving telaprevir with pegylated-interferon/ribavirin than in those receiving pegylated-interferon/ribavirin alone.
- Trial name
- NCT02881034
- Testing
- Triple therapy
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Hospices Civils de Lyon
Renal Insufficiency, Chronic, Kidney Diseases
Validation of New Markers of Glomerular Filtration Rate: Dota Gadolinium and Calcium EDTA (MultiGFR)
The purpose of this study is to validate in comparison to a reference method (inuline) two novel non-radioactive biomarkers for glomerular filtration rate (GFR) measurement in chronic-kidney disease (CKD) patients and in healthy…
- Trial name
- MultiGFR (NCT02286258)
- Testing
- Calcium EDTA, Gd-DOTA
- Where
- 4 sites in France
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Kidney Disease
Efficacy and Safety of the Ultrasound Stimulation Device NEFRONIX in Patients With Chronic Kidney Disease
This study is a prospective, multicenter, single-arm, open-label, non-randomized exploratory clinical trial designed to evaluate the safety and potential efficacy of an ultrasound stimulation device (NEFRONIX G-01) in patients…
- Trial name
- NCT07339098
- Testing
- Ultrasound Stimulation (NEFRONIX G-01)
- Volunteers
- 20 people
- Sponsor
- Anasonic
Renal Transplant
Measuring Kidney Function in Kidney Transplantation
Kidney transplantation is the preferred treatment for permanent kidney failure. Following transplantation, the kidney function must be followed closely to detect problems so that investigations and appropriate treatment can be…
- Trial name
- NCT00212979
- Testing
- non intervention study
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Ottawa Hospital Research Institute
Chronic Kidney Disease, End-Stage Renal Disease
Medication Intervention in Transitional Care to Optimize Outcomes & Costs for CKD & ESRD
Transitional care strategies focused on enhancing the accuracy and comprehensiveness of medication information transfer will lead to improved health outcomes among hospitalized patients with chronic kidney disease.
- Trial name
- CKD/ESRD-MIT (NCT01459770)
- Testing
- Medication Information Transfer Intervention, Usual care for hospital discharge
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Providence Medical Research Center
Interstitial Fibrosis, Kidney Transplant; Complications
Fingolimod for the Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation
This is a randomized, double-blind, placebo-controlled trial in de novo kidney transplant patients to determine if the addition of fingolimod (brand name Gilenya®, candidate name- FTY720) on the background of standard…
- Conditions
- Interstitial Fibrosis, Kidney Transplant; Complications, Kidney Transplant Rejection, Kidney Transplant Failure and Rejection
- Trial name
- NCT05285878
- Testing
- Fingolimod
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Methodist Hospital Research Institute
Healthy
L-NMMA Dose-response Study in Healthy Subjects
The purpose of this study is to investigate the effect of different levels of nitric oxide inhibition on blood pressure and arterial stiffness in healthy subjects.
- Trial name
- NCT01070940
- Testing
- NG-monomethyl-L-arginine (L-NMMA)
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Chronic Kidney Diseases
Comparison of Different Gfr Measurements in Chronic Kidney Diseases
Comparison of different Gfr measurements in Chronic Kidney Diseases
- Trial name
- NCT05696028
- Testing
- Gamma counter
- Volunteers
- 166 people
- Sponsor
- Assiut University
Type 2 Diabetes Mellitus, Diabetic Nephropathy
Effects of Spironolactone Combination Therapy on Proteinuria, Kidney Function, and Blood Pressure
The detrimental effects of aldostrone are not adequately arrested by the use of angiotensin converting enzyme (ACE), angiotensin II receptor blocker (ARB) or a combination of both.
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Nephropathy, Essential Hypertension
- Trial name
- NCT01667614
- Testing
- spironolacone 25 mg tablets added to losartan
- Where
- Iran
- Volunteers
- 136 people
- Sponsor
- Tehran University of Medical Sciences
Acute Circulatory Failure
Measuring the Plasma Clearance of Iohexol to Estimate Glomerular Filtration Rate in Intensive Care Unit Patients: Preliminary Feasibility Study
The objective of this study is to assess the feasibility of estimating the clearance of iohexol as an indirect measure of glomerular filtration rate in patients with unstable renal function in the intensive care unit through…
- Trial name
- IoxRea (NCT02050269)
- Testing
- Iohexol
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Glomerular Filtration Rate, Heart Failure
MediBeacon® Transdermal GFR System for the Evaluation of Kidney Function in Adults With Heart Failure
The goal of this clinical trial is to evaluate the accuracy and feasibility of transdermal glomerular filtration rate (tGFR) assessment using relmapirazin (Lumitrace) and the MediBeacon tGFR system compared to plasma clearance…
- Trial name
- NCT07349797
- Testing
- Lumitrace, MediBeacon Transdermal Glomerular Filtration Rate Measurement System (tGFR), Iohexol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- MediBeacon
Kidney Transplantation
Performance of Cimetidine-corrected MDRD Equation in Renal Transplant Patients
Among the different creatinine-based GFR predicting equations, the MDRD equation gives the best prediction in renal transplantation but does not provide the level of accuracy usually seen in renal patients with native kidneys.
- Trial name
- NCT00475059
- Testing
- cimetidine arrow
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cardiac Surgery
Evaluation of Renal Function in Subjects Who Had Undergone Cardiac Surgery
To evaluate the differences between serum cystatin C based estimated glomerular filtration rate (eGFRcys), serum creatinine based eGFR (eGFRcreat) and measured glomerular filtration rate (mGFR) in subjects at high risk for acute…
- Trial name
- NCT04654221
- Testing
- mGFR by iohexol clearance
- Where
- 6 sites in United States
- Volunteers
- 16 people
- Sponsor
- Quark Pharmaceuticals