Clinical trials: GI Disorders
Dysphagia, Aspiration
PEG by Introducer Method Via EG Scan
Percutaneous endoscopic gastrostomy(PEG) by introducer method has been proven to be safe and easy to perform. However, it is limited by its need to be performed in an endoscopy unit. E.G.
- Conditions
- Dysphagia, Aspiration, Esophageal Stenosis
- Trial name
- NCT02183207
- Testing
- Percutaneous Endoscopic Gastrostomy
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- The Catholic University of Korea
Dehydration, Acute Gastroenteritis
Assessment of Volume Status by Bedside Ultrasound in Children With Acute Gastroenteritis
The purpose of the study is assessment of volume status by bedside ultrasound in children with acute gastroenteritis
- Trial name
- NCT03021109
- Testing
- Measurement of inferior vena cava diameters with ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people
- Sponsor
- Derince Training and Research Hospital
Carcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
This trial will look at a drug called sigvotatug vedotin (SGN-B6A) alone and with pembrolizumab, with or without chemotherapy, to find out whether it is safe for people who have solid tumors.
- Conditions
- Carcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck, HER2 Negative Breast Neoplasms, Esophageal Squamous Cell Carcinoma
- Trial name
- NCT04389632
- Testing
- sigvotatug vedotin, pembrolizumab, cisplatin
- Where
- 158 sites in United States, France and 5 more
- Volunteers
- 1,006 people
- Sponsor
- Seagen, a wholly owned subsidiary of Pfizer
Rectal Carcinoma
Pattern of Treatment and Outcomes of Locally Advanced Rectal Carcinoma
the study will discuss different pattern of treatment and the outcomes of locally advanced rectal carcinoma as a retrospective study.
- Trial name
- NCT07363863
- Testing
- No Intervention (subjects were previously treated with Onglyza®)
- Volunteers
- 100 people
- Sponsor
- Sohag University
Dysphagia
Oral Enteral Nutrition in Delayed Onset Radiotherapy-related Swallowing Disorder in Nasopharyngeal Carcinoma
This is a prospective multicenter study with patients with delayed dysphagia after radiotherapy for NPC. Patients enrolled are randomly divided equally into the observation group and the control group.
- Trial name
- NCT06301763
- Testing
- Intermittent Oral-esophageal Tube Feeding, nasogastric tube feeding
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Muhammad
Head and Neck Cancer, Lung Cancer
Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies
This research is being done to collect and store biological specimens (biospecimens) from people with cancer, regardless of tumor type, who are receiving treatments known or thought to have an effect on the immune system.
- Conditions
- Head and Neck Cancer, Lung Cancer, Gastrointestinal Cancer
- Trial name
- NCT05995821
- Testing
- Collection of biological specimens
- Where
- United States
- Volunteers
- 1,250 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Gastro Intestinal Bleed
Validation of a New Score for UGI Bleeding in the ED: the Study of the TU-GIB Score
We have developed a new reliable, easy and reproducible clinical and biological score to select patients presenting to the emergency department with upper GI bleeding and at high risk of developing complications in order to plan…
- Trial name
- TU-GIBscore (NCT05646433)
- Where
- Tunisia
- Volunteers
- 500 people
- Sponsor
- Hôpital Universitaire Sahloul
Gastric Cancer
Neoadjuvant Chemotherapy for Patients With Advanced Gastric Cancer in ERAS Programs for Radical Gastrectomy
Patients with advanced gastric cancer received neoadjuvant chemotherapy undergo enhanced recovery after surgery (ERAS) programs.
- Trial name
- NCT03238404
- Testing
- NAC group, Surgery alone group
- Where
- China
- Volunteers
- 88 people
- Sponsor
- JIANG Zhi-Wei
Colorectal Cancer
Tertiary Prevention by Exercise in Colorectal Cancer Therapy
The purpose of this study is to determine the feasibility of a one year exercise training program in post-surgical patients with colorectal cancer.
- Trial name
- F-PROTECT (NCT01991847)
- Testing
- Physical activity
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Technical University of Munich
Neoplasms, Colorectal
Phase I/II Study of Lapatinib in Combination With Oxaliplatin and Capecitabine in Subjects With Advanced Colorectal Cancer
The purpose of this study is to determine the highest, tolerated dose level and safety of lapatinib, capecitabine and oxaliplatin in subjects with advanced cancer and to determine the clinical activity of the combination of drugs…
- Trial name
- NCT00536809
- Testing
- lapatinib, oxaliplatin, capecitabine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- GlaxoSmithKline
Appendicitis
A Randomized Controlled Trial on Wound Irrigation in Open Appendectomy.
A large retrospective study compared wound irrigation with antiseptic solution, with antimicrobial agent, and with normal saline in patients undergoing open appendectomy and concluded an evident superiority of antibiotic wound…
- Trial name
- NCT04332809
- Testing
- saline-gentamicin irrigation, saline irrigation
- Where
- Egypt
- Volunteers
- 208 people
- Sponsor
- Mansoura University
Irritable Bowel Syndrome
Probiotics and Irritable Bowel Syndrome
This clinical trial was conducted on 90 IBS patients, who fulfill ROME IV criteria and the IBS diagnostic questionnaire (Arabic version licensed by Rome Foundation) in Egyptair hospital outpatient clinic, Cairo, Egypt between May…
- Trial name
- NCT04572932
- Testing
- lactobacillus delbruekii
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Crohn Disease
Prevention of Postoperative Endoscopic Recurrence With Endoscopy-driven Versus Systematic Biological Therapy
With this prospective, randomized, multicentre, parallel group pragmatic non-inferiority trial, the investigators will evaluate if endoscopy-driven introduction of biological therapy is not leading to more postoperative…
- Trial name
- SOPRANO-CD (NCT05169593)
- Testing
- Biological Drug
- Where
- 28 sites in Belgium, Italy
- Volunteers
- 292 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colorectal Cancer
Phase II Trial Assessing Efficacy and Toxicity of Capecitabine and Oxaliplatin in the Treatment of Colorectal Cancer
To assess the efficacy and safety of the combination of capecitabine and oxaliplatin in the 1st, 2nd or subsequent line treatment of metastatic colorectal cancer, and also in the neo-adjuvant and adjuvant setting of resectable…
- Trial name
- NCT00220116
- Testing
- Capecitabine, Oxaliplatin
- Where
- United Kingdom
- Volunteers
- 172 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Colon Cancer, IBS
Patient Satisfaction With Propofol for Out Patient Colonoscopy
The primary purpose of this study is to determine if patient satisfaction with propofol is better than with non-propofol anesthesia for outpatient colonoscopies.
- Conditions
- Colon Cancer, IBS, Polyps
- Trial name
- NCT02937506
- Testing
- Propofol, Fentanyl Plus Midazolam
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mount Carmel Health System
Colorectal Cancer
Early Detection and Risk Stratification of Colorectal Cancer Based on miRNA Platform
This is a prospective, observational cohort study to establish the minimal residual disease (MRD) model for predicting relapse risk and identifying disease recurrence in patients with colorectal adenocarcinoma based on the miRNA…
- Trial name
- NCT06351384
- Testing
- miRNA detection test
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Stress, Constipation
The Effects Of Probiotics On Stress Among Healthy Adults From Umm Al-Qura University At Makkah
The goal of this clinical trial is to study the effects of probiotic supplementation on stress levels and bowel habits in healthy Saudi adults for both males and females.
- Conditions
- Stress, Constipation, Anthropometry, Bowel Disease
- Trial name
- NCT06464484
- Testing
- Probiotics (Lactobacillus rhamnosus GG (ATCC 53103)
- Where
- Saudi Arabia
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Adenomatous Polyposis Coli, Familial Adenomatous Polyposis
Cold Atmospheric Plasma for the Endoscopic Treatment of Duodenal Polyps in Patients With Familial Adenomatous Polyposis
The objective of this study is to investigate the feasibility for the treatment of precancerous peri-ampullary FAP polyps in the duodenum using low-thermal argonplasma.
- Conditions
- Adenomatous Polyposis Coli, Familial Adenomatous Polyposis, Duodenal Adenoma
- Trial name
- coldAPC (NCT06435533)
- Testing
- low energy argonplasma coagulation
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Schistosomiasis, Anemia
Schistosomiasis Effect on Response to Vaccines, Anaemia and Nutritional Status of Children of Northern Senegal
SchistoVAN aims to study the role of schistosomiasis infection in the modulation of the immune response of children to childhood vaccine antigens, as well as the impact of this infection on their nutritional status and their…
- Conditions
- Schistosomiasis, Anemia, Underweight, Stunting
- Trial name
- SchistoVAN (NCT01553552)
- Where
- Senegal
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Biomedical Research Center EPLS
Colon Cancer
Endoscopic Therapy Or Surgery for Early Colon Cancer
The trial is a randomized head-to-head comparison of the benefits, harms and burdens of endoscopic full-thickness resection (eFTR), a novel, minimally invasive endoscopic treatment modality, for early colon cancer as compared to…
- Trial name
- ETHOS (NCT06940947)
- Testing
- eFTR, Surgery
- Where
- Poland
- Volunteers
- 434 people
- Sponsor
- Norwegian Department of Health and Social Affairs
The first 5,000 results can be paged through. Add a filter or change the sort order to reach the rest.