Clinical trials: GI Symptoms
Risk Factors, Complication of Surgical Procedure
ACUTE-Acute Surgical Care- Risk Factors and Outcomes for Patients in Need of Acute Surgical Care
Observational retrospective study of patients in need of acute surgical care admitted to Skåne University Hospital between 2009 and 2019.
- Conditions
- Risk Factors, Complication of Surgical Procedure, Complication of Treatment, Complication of Anesthesia
- Trial name
- ACUTE (NCT05195697)
- Testing
- Observational study of different treatments and time to treatment
- Where
- Sweden
- Volunteers
- 3,000 people
- Sponsor
- Region Skane
Active Peptic Ulcer Disease/GI Bleeding
Efficacy of Hemostasis by Soft Coagulation Using Endoscopic Hemostatic Forceps for Acute Peptic Ulcer Bleeding
Endoscopic high-frequency soft coagulation is available for the management of bleeding or nonbleeding visible vessels during endoscopic submucosal dissection.
- Trial name
- NCT02020603
- Testing
- epinephrine injection plus soft coagulation using hemostatic forceps, epinephrine injection plus argon plasma coagulation
- Where
- South Korea
- Volunteers
- 151 people
- Sponsor
- Kyunghee University Medical Center
PCIA, Frailty
Impact of Frailty on Nalbuphine Dose for Postoperative Analgesia in Elderly Patients Undergoing Laparoscopic GI Surgery
This study aims to investigate the ED50 and ED95 of nalbuphine combined with dexmedetomidine in patient-controlled intravenous analgesia (PCIA) for elderly patients with different degrees of frailty, as well as their analgesic…
- Conditions
- PCIA, Frailty, Laparoscopic Gastrointestinal Surgery
- Trial name
- NCT06953570
- Volunteers
- 120 people
- Sponsor
- Yongtao Sun
Gastro Intestinal Bleeding
Detection of Gastrointestinal Bleeding in Intensive Care Patients Via Biosensor Watch
The purpose of this study to improve methods of monitoring and diagnosing gastrointestinal bleeding via the E4 wristband, a biosensor watch.
- Trial name
- NCT03874169
- Testing
- E4 wristband
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Columbia University
Chronic Diarrhea, Persistent Vomitting
Pediatric GI Endoscopy at Assiut University
1. To evaluate the diagnostic role, and outcomes of upper and lower gastrointestinal (GI) endoscopy in identifying gastrointestinal disorders among infants and pediatric patients attending Assiut University Children Hospital. 2.
- Conditions
- Chronic Diarrhea, Persistent Vomitting, Gastrointestinal Bleeding, Dysphagia
- Trial name
- NCT07239934
- Testing
- Gastrointestinal Endoscopy
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Short Bowel Syndrome
Exenatide on GI Motor Function and Permeability in Short Bowel Syndrome
We plan to examine the gastrointestinal (GI) physiologic profile of Exenatide, a glucagon-like peptide (GLP-1) analog as a possible intestino-trophic growth factor capable of inducing small bowel adaptation and regeneration in…
- Trial name
- NCT01818648
- Testing
- Exenatide
- Sponsor
- Mayo Clinic
Upper GI Bleeding
Clinical Risk Scores in Prediction Outcome of Acute UGIT Bleeding in Non Cirrhotic Patients
To compare the ability of 4 bleeding risk scoring systems (Glasgow -Blatchford score, MAP, H3B2 and ABC scores ) in prediction of: Need of intervention, Re bleeding, Thirty-day mortality, length of hospital stay
- Trial name
- NCT06254352
- Testing
- scoring system
- Volunteers
- 100 people
- Sponsor
- Assiut University
Abdominal Massage, Enteral Nutrition
Effect of Abdominal Massage on Gastrointestinal Symptoms After Head and Neck Cancer Surgery
This study aimed to evaluate whether abdominal massage could reduce abdominal pain, constipation, and gas/bloating in patients receiving enteral nutrition through a nasogastric tube after surgery for head and neck cancer.
- Conditions
- Abdominal Massage, Enteral Nutrition, Nasogastric Feeding, Head and Neck Surgery
- Trial name
- HNC-AM (NCT07889011)
- Testing
- Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Maltepe University
Iron Deficiency Anemia, Iron Overload
Iron Supplementation and Side Effects
The objective of this study is to examine patient-reported gastrointestinal side effects, as well as iron status indicators, inflammatory markers and oxidative stress following administration of ferrous sulfate and iron-enriched…
- Trial name
- NCT04018300
- Testing
- Ferrous sulfate, Aspiron
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Gastrointestinal Diseases
Correlation of Toxins With Gastrointestinal (GI) and Overall Health
The goal of this observational study is to evaluate the levels of urinary environmental toxins, heavy metals, PFAS and mycotoxins with gastrointestinal (GI) and overall health.
- Trial name
- NCT06278311
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Vibrant America Clinical Lab
Acute Upper Gastrointestinal Hemorrhage
Endoscopic Treatment of Recurrent Upper GI Bleeding: OTSC [Over the Scope Clip] Versus Standard Therapy
Prospective-randomized trial. Patients with recurrent bleeding from gastroduodenal ulcers are randomized into either endoscopic treatment with the OTSC [Over The Scope Clip] or endoscopic standard therapy.
- Trial name
- STING (NCT01836900)
- Testing
- Endoscopic hemostasis
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Kliniken Ludwigsburg-Bietigheim gGmbH
Coronary Heart Disease, GI Bleeding
Platelet Inhibitory Effect of Clopidogrel in Patients Treated With Omeprazole, Pantoprazole, or Famotidine
Current guidelines recommend the addition of proton pump inhibitors (PPI) to patients taking double anti-platelet therapy (Aspirin and Clopidogrel) to prevent upper GI bleeding1.
- Trial name
- NCT00950339
- Testing
- omeprazole, 20mg twice daily, famotidine 40mg twice daily, pantoprazole 40mg once daily
- Where
- Israel
- Volunteers
- 63 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Venous Thromboembolism, Gastro Intestinal Bleeding
Reducing Gastrointestinal Bleeding With Proton Pump Inhibitor Therapy in Acute Venous Thromboembolism
The investigators are studying whether treatment with a proton pump inhibitor called omeprazole reduces gastrointestinal bleeding in older adults taking blood thinners for a blood clot (venous thromboembolism).
- Conditions
- Venous Thromboembolism, Gastro Intestinal Bleeding, Blood Clot
- Trial name
- NCT06393868
- Testing
- Omeprazole 20 mg Oral Tablet
- Where
- 7 sites in Canada
- Volunteers
- 360 people
- Sponsor
- Ottawa Hospital Research Institute
Irritable Bowel Syndrome (IBS)
EFFECT OF A DİETİTİAN-SUPERVİSED LOW-FODMAP DİET VERSUS STANDARD WRİTTEN ADVİCE ON GASTROİNTESTİNAL SYMPTOMS AND INFLAMMATORY BİOMARKERS İN IRRİTABLE BOWEL SYNDROME: A RANDOMİZED CONTROLLED TRİAL
Background: Irritable Bowel Syndrome (IBS) is the most prevalent functional gastrointestinal (GI) pathology among GI disorders. Various dietary interventions, particularly the low-FODMAP diet, are employed to alleviate IBS…
- Trial name
- NCT07619573
- Testing
- Low-FODMAP Diet Intervention
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
Sucrase-Isomaltase Deficiency, Irritable Bowel Syndrome
The Effect of Sugar Load in IBS Patients Depending on Sucrase-isomaltase Genes
The investigators know that many patients with irritable bowel syndrome (IBS) have functional variants of genes coding for sucrase-isomaltase enzymes.
- Trial name
- NCT05688826
- Testing
- Sugar
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Region Skane
Adenomyosis of Uterus
The Efficacy of High-Intensity Focused Ultrasound Therapy on Adenomyosis
To assess the efficacy of High-Intensity Focused Ultrasound on adenomyosis
- Trial name
- HIFU (NCT07808034)
- Testing
- High Intensity Focused Ultrasound
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Far Eastern Memorial Hospital
Gastrointestinal Cancer, Dietary Modification
Study of Parenteral Nutrition to Patients With Gastrointestinal Cancer
Clinical background: Weight loss is a common problem in patients suffering from gastrointestinal cancer. It is demonstrated that the prognosis for cancer patients with weight loss is worse than that for weight stable patients.
- Conditions
- Gastrointestinal Cancer, Dietary Modification, Cancer Cachexia, Quality of Life
- Trial name
- NCT02066363
- Testing
- Dietician advise, Parenteral nutrition
- Where
- Denmark
- Volunteers
- 47 people
- Sponsor
- Odense University Hospital
Peptic Ulcer Hemorrhage
The Dissemination of Consensus Recommendations on Upper Gastrointestinal Bleeding
The purpose of this study is to assess whether adherence to NVUGIB guidelines is improved with implementation of a national, tailored multifaceted intervention.
- Trial name
- REASON-II (NCT00840008)
- Testing
- Educational intervention
- Volunteers
- 3,157 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Maintenance Kidney Transplant
Gastrointestinal and Health-related Quality of Life in Kidney Transplant Patients Treated With Mycophenolate Mofetil
This study will assess the quality of life in renal transplant recipients who require a reduced dose of mycophenolate mofetil (MMF) because of gastrointestinal (GI) side effects and will also access the relationship between…
- Trial name
- NCT00400647
- Testing
- Enteric-coated Mycophenolate sodium (EC-MPS), Mycophenolate mofetil
- Where
- Switzerland
- Volunteers
- 136 people
- Sponsor
- Novartis
Parkinson's Disease
Deep Brain Stimulation and Digestive Symptomatology
Patients with Parkinson's disease (PD) frequently experience upper gastrointestinal disorders. During the disease, weight loss is often noticed.
- Trial name
- SCPDig (NCT00639275)
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Rouen