Clinical trials: GI Symptoms
Iron Supplementation and Gastrointestinal Health, Iron Deficiency
Modulation of hepcidIN With Co-supplementation of Iron and FORMulated Curcumin in Recreational Athletes
Iron deficiency and iron deficiency anaemia are common among endurance athletes partly due to a repeated post-exercise elevation of hepcidin, a hormone limiting iron entry through the intestine.
- Trial name
- IN-FORM (NCT07078630)
- Testing
- HydroCurc®, Ferrous sulphate 200mg oral tablet providing 65 mg of elemental iron
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Westminster
Chronic Diarrhea, Persistent Vomitting
Pediatric GI Endoscopy at Assiut University
1. To evaluate the diagnostic role, and outcomes of upper and lower gastrointestinal (GI) endoscopy in identifying gastrointestinal disorders among infants and pediatric patients attending Assiut University Children Hospital. 2.
- Conditions
- Chronic Diarrhea, Persistent Vomitting, Gastrointestinal Bleeding, Dysphagia
- Trial name
- NCT07239934
- Testing
- Gastrointestinal Endoscopy
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Upper Gastrointestinal Bleeding
Risk Stratification of Patients Presenting With Upper Gastrointestinal Bleeding to the Emergency Department Using AIMS65 Score and Red Cell Distribution Width
The rationale of this study in UGIB patients is to assess whether the prediction of mortality and morbidity using AIMS65 score improves when used in combination with RDW in the emergency department setting.
- Trial name
- RUGBE (NCT04825977)
- Testing
- RISK STRATIFICATION USING AIMS65 SCORE AND RDW
- Where
- India
- Volunteers
- 348 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Gut Health, Gastrointestinal Symptoms
IgG Binding Protein LT in Support of a Healthy Gut on the Go
PS52 is a randomized, double-blind, placebo-controlled, fully decentralized study sponsored by Bactolife A/S and conducted by People Science, Inc.
- Conditions
- Gut Health, Gastrointestinal Symptoms, Safety in Healthy Adults
- Trial name
- NCT07873957
- Testing
- IgG Binding Protein LT
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Bactolife A/S
Disorder of Upper Gastrointestinal Tract, Pancreatic Nodule
Tissue Characterisation by Endoscopic GI-elastography
In this single centre study we study the use of endoscopic ultrasonography (EUS) combined with elastography in order to separate malignant tissue from benign tissue in and adjacent to the upper gastrointestinal tract.
- Conditions
- Disorder of Upper Gastrointestinal Tract, Pancreatic Nodule, Secondary and Unspecified Malignant Neoplasm of Retroperitoneal Lymph Nodes, Secondary Malignant Neoplasm of Lymph Node
- Trial name
- NCT01360411
- Where
- Norway
- Volunteers
- 137 people
- Sponsor
- Haukeland University Hospital
Autism
Prebiotic Intervention for Autism Spectrum Disorders
The purpose of this study is to determine the effect of a prebiotic (BGOS) on gut microbiota and metabolites in children with autism spectrum disorders.
- Trial name
- NCT02720900
- Testing
- B-GOS, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- Clasado Limited
Gastrointestinal Symptoms, Small Intestinal Overgrowth
Proton Pump Inhibitors and Gastrointestinal Symptoms
The aim of the study is to evaluate the potential protective effect of Lactobacillus paracasei subspecies paracasei F19 administration on bowel symptom onset in patients with gastro-esophageal reflux disease at long-term PPI…
- Trial name
- NCT02054455
- Testing
- Lactobacillus paracasei F19
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Federico II University
Upper Gastrointestinal Bleeding
Capsule Endoscopy for HEmorrhage in the ER
This is a multi-center randomized controlled trial examining the use of Video Capsule Endoscopy (VCE) to discharge low-moderate risk patients with suspected upper gastrointestinal bleeds (UGIB) from the Emergency Department (ED.)…
- Trial name
- CHEER (NCT03458000)
- Testing
- PillCam UGI, Standard of Care
- Where
- 3 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- George Washington University
Healthy
Efficacy of Dietary Supplement in Subjects With Acid Reflux and/or Abdominal Bloating/Distention and GI Symptoms
This study was a prospective randomized clinical study. There was interventional treatment for a total of 8 weeks including a 2-week washout period.
- Trial name
- NCT06808867
- Testing
- Dietary Supplement with Active Ingredient Blend
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Olly, PBC
Cancer of the Gastrointestinal Tract, Cancer of Unknown Origin
A Clinical Safety and Efficacy Study of Mebendazole on GI Cancer or Cancer of Unknown Origin.
This study will evaluate the safety and efficacy of mebendazole (ReposMBZ) in patient with advanced gastrointestinal cancer or cancer of unknown origin.
- Trial name
- RepoMeb (NCT03628079)
- Testing
- ReposMBZ
- Where
- Sweden
- Volunteers
- 11 people
- Sponsor
- Repos Pharma
Gastroesophageal Reflux Disease
Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease
The aims of this study are to create a prospective data base to evaluate the long term outcomes of medical and surgical treatment of gastroesophageal reflux disease (GERD); to measure standard outcomes as well as patient derived…
- Trial name
- NCT00260572
- Testing
- Questionnaires to evaluate QOL, Questionnaires to evaluate heartburn and quality of life, Questionnaire to evaluate satisfaction with treatment
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- University of Pittsburgh
Common Variable Immunodeficiency
Immune System and Gut Abnormalities in Patients With Common Variable Immunodeficiency With and Without Gastrointestinal Symptoms
This study will determine whether people with common variable immunodeficiency (CVID) with and without gastrointestinal (GI) symptoms have gut abnormalities (inflammation or loss of function) and changes in immune system cells…
- Trial name
- NCT00015431
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Gastroenteritis Acute, Gastrointestinal Symptoms
Diagnostic PCR Panel in Children With Acute Gastrointestinal Symptoms
This investigator-initiated randomized controlled trial compares the clinical impact of real time PCR of fecal samples in children with acute gastrointestinal symptoms at a pediatric emergency room.
- Conditions
- Gastroenteritis Acute, Gastrointestinal Symptoms, Abdominal Pain/ Discomfort, Vomiting in Infants and/or Children
- Trial name
- RealCAGI RCT (NCT07280624)
- Testing
- Multiplex PCR gastrointestinal panel
- Volunteers
- 526 people
- Sponsor
- University of Oulu
Gastrointestinal Symptoms
Dyclonine vs. Tetracaine for Local Anesthesia in Unsedated Gastroscopy
Gastroscopy is a key diagnostic approach for upper gastrointestinal diseases, but pharyngeal passage of the gastroscopy often causes participants' discomfort.
- Trial name
- NCT07691346
- Testing
- Dyclonine hydrochloride mucilage, Tetracaine Hydrochloride Jelly
- Where
- China
- Volunteers
- 208 people
- Sponsor
- General Hospital of Shenyang Military Region
Fibromyalgia
Effects of Box Breathing Exercise in Patients With Fibromyalgia
Fibromyalgia is a chronic condition that can cause widespread pain, sleep problems, fatigue, gastrointestinal symptoms, and reduced comfort.
- Trial name
- NCT07722923
- Testing
- Box Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Artvin Coruh University
H Pylori Infection
Prevalence of Asymptomatic H Pylori Infection Among Patients Undergoing PCI and Impact of Its Eradication on Occurrence of GIT Symptoms and Bleeding"
In the present study, the aim was to report the prevalence of positive H. pylori infection in an unselected population referred for coronary intervention and likely to required DAPT or DPI, also the study assessed impact of H.
- Trial name
- NCT07487142
- Testing
- BISMUTH TETRACYCLINE METRONIDAZOLE OMEPRAZOLE
- Where
- Egypt
- Volunteers
- 121 people
- Sponsor
- Beni-Suef University
Gastrointestinal Diseases, Foodborne Diseases
Health Impacts of Street Vended Fruits
This study will employ a randomized controlled intervention design to evaluate the health impacts of consuming fresh-cut street-vended fruits, focusing on microbial contamination and gastrointestinal (GI) symptoms.
- Conditions
- Gastrointestinal Diseases, Foodborne Diseases, Microbial Contamination, Street Vended Foods
- Trial name
- HISVF (NCT06858046)
- Testing
- Fresh-Cut Guava Consumption, Fresh-Cut Pineapple Consumption, Fresh-Cut Watermelon Consumption
- Where
- Bangladesh
- Volunteers
- 639 people, healthy volunteers welcome
- Sponsor
- Bangladesh Agricultural University
Autism Spectrum Disorder, Autism
Autism Spectrum Disorder (ASD) Neurodevelopmental Disorder With Issues Social Behavior, Communication Issues, GI Dysfunction. Study is Multimodal Interventions Targeting These Pathways With cSVF, Stored MSCs, FMT and Diet Modification. Role of Autoimmunity, Gut-brain Issues, & Issues Examined.
Autism spectrum disorder (ASD) is a neurodevelopmental condition with core deficits in social communication and behavior, often accompanied by gastrointestinal (GI) and metabolic dysfunction.
- Conditions
- Autism Spectrum Disorder, Autism, Autism Spectral Disorder
- Trial name
- GARM-Autism (NCT07546942)
- Testing
- Autologous MSC isolation, concentration, and cryopreservation of adult mesenchymal stem cells, Fecal Biomicrome Transplantation (FMT), Ketogenic RESET Diet Protocol
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Black Tie Medical, Inc.
Gastro Intestinal Bleeding
Efficacy of Tranexamic Acid in Upper Gastrointestinal Bleeding
Upper Gastrointestinal bleed is a common presentation in a medical emergency. Patients generally present with hematemesis, melena or in severe cases hematochezia.
- Trial name
- NCT04788121
- Testing
- Tranexamic acid, Standard of care
- Where
- India
- Volunteers
- 160 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Ultra-endurance Athletes With Gastrointestinal Symptoms
Effects of Probiotics and Nutritional Status on Exercise-Induced Symptoms, and Endurance Performance in Ultra-Endurance Athletes
Ultra-endurance athletes have been commonly endured extreme conditions during races and training sessions, resulting in exercise-associated clinical symptoms, including gastrointestinal symptoms, dehydration, and elevated…
- Trial name
- NCT04779281
- Testing
- Oral Rehydration Salts supplemented with L. Rhamnosus GG, Oral Rehydration Salts only
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul Medeniyet University