Clinical trials: GI Symptoms
Ventral Hernia
Gastrointestinal Tract Recovery in Patients Undergoing Open Ventral Hernia Repair
The purpose of this study is to determine whether Alvimopan (Entereg) in ventral hernia surgery patients is associated with accelerated gastrointestinal recovery and reduced length of hospital stay compared to placebo controls.
- Trial name
- NCT02379858
- Testing
- Alvimopan
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Medical College of Wisconsin
Bulimia Nervosa, Eating Disorders
Effectiveness of Antibiotic Treatment for Reducing Binge Eating and Improving Digestive Function in Bulimia Nervosa
This study will determine the effectiveness of the antibiotic erythromycin in enhancing gastrointestinal function and decreasing the frequency of binge eating in people with bulimia nervosa.
- Trial name
- NCT00304187
- Testing
- Erythromycin
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Gastric Ulcer, Duodenal Ulcer
Long Term Study to Investigate the Efficacy & Safety of D961H (Esomeprazole) for the Prevention of NSAIDs-induced Ulcer
The purpose of this study is to assess the Safety and tolerability of D961H (Esomeprazole) 20 mg once daily for up to 52 weeks of treatment involving patients with a history of gastric and/or duodenal ulcers receiving daily…
- Conditions
- Gastric Ulcer, Duodenal Ulcer, Rheumatoid Arthritis, Osteoarthritis
- Trial name
- NCT00595517
- Testing
- Esomeprazole 20 mg
- Where
- 3 sites in Japan
- Volunteers
- 395 people
- Sponsor
- AstraZeneca
Gastrointestinal Cancer, Depression
Ketamine-assisted Psychotherapy (KAP) for Patients With Existential Distress Associated With Non-operable GI Cancers
The goal of this open-label clinical trial is to assess the feasibility of Ketamine-assisted psychotherapy (KAP) studies for adults with non-operable GI cancers suffering with existential distress.
- Conditions
- Gastrointestinal Cancer, Depression, Anxiety
- Trial name
- TREK (NCT06001372)
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Utah
Group B Streptococcus Carrier in Childbirth, Gastrointestinal Symptoms
The Efficacy of Probiotics to Reduce Antepartum Group B Streptococcus Colonization.
This study is a randomized double blind, placebo controlled trial to determine the efficacy of an oral probiotic in reducing antenatal Group B Streptococcus colonization.
- Trial name
- NCT03696953
- Testing
- Florajen3
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Marquette University
Myelodysplastic Syndrome, Transfusional Iron Overload
Myelodysplastic Syndrome (MDS) Gastrointestinal (GI) Tolerability Study
The objective of the study is to evaluate and compare the frequency and severity of GI adverse events in different dose administration regimens.
- Trial name
- MACS1574 (NCT01326845)
- Testing
- Deferasirox
- Where
- 10 sites in France, Italy and 2 more
- Volunteers
- 12 people
- Sponsor
- Novartis Pharmaceuticals
Gastrointestinal Symptoms, Heart Transplantation
Enteric-coated Mycophenolate Sodium (Myfortic®) in Heart Transplant Recipients
Mycophenolate sodium (Myfortic®) is a newly developed enteric-coated tablet version of mycophenolate mofetil (Cellcept®) which is currently used as therapy for the prevention of transplant rejection.
- Trial name
- NCT00574197
- Testing
- Mycophenolate Sodium
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Cedars-Sinai Medical Center
Obesity
Study for Short Term Weight Loss in Candidates for Bariatric Surgery
The purpose of this study is to determine whether the GI Endobarrier Liner is safe and effective.
- Trial name
- NCT00985491
- Testing
- Endobarrier Liner
- Where
- Chile
- Volunteers
- 46 people
- Sponsor
- Morphic Medical Inc.
Renal Transplantation
A Study Designed to Compare the Tolerability of an Increased Dose of Enteric-coated Mycophenolate Acid (MPA) in Renal Transplant Patients Whose Dose of Mycophenolate Mofetil (MMF) Was Reduced Due to Gastrointestinal Symptoms
To determine if conversion to enteric coated MPA allows an escalated dose of mycophenolic acid (MPA) to be tolerated in patients experiencing gastrointestinal (GI) symptoms
- Trial name
- NCT00658333
- Testing
- Enteric-coated Mycophenolate Acid (EC-MPA), Mycophenolate Mofetil (MMF)
- Where
- 37 sites in United States
- Volunteers
- 30 people
- Sponsor
- Novartis Pharmaceuticals
Fibromyalgia, Gastrointestinal Disease
Probiotic VSL#3 for the Treatment of Gastrointestinal Symptoms Associated to Fibromyalgia
The study evaluated the efficacy and tolerability of probiotic VSL#3 for the treatment of gastrointestinal symptoms in patients with fibromyalgia; 50% of the participants received probiotic and the remaining 50% received matching…
- Trial name
- NCT04256785
- Testing
- VSL#3
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Elena Pita Calandre
Gastroesophageal Reflux Disease
Efficacy of Pantoprazole 20/40 mg Once Daily (od) in Patients Older Than 12 Years Who Have Gastrointestinal Symptoms of Reflux Disease
The aim of this study was to evaluate the effect of 14 days treatment with Pantoprazole 40 mg and 20 mg on gastroesophageal reflux disease (GERD) related symptoms in a large patient population.
- Trial name
- PARADE (NCT00829738)
- Testing
- Pantoprazole
- Where
- 717 sites in Germany
- Volunteers
- 4,188 people
- Sponsor
- Nycomed
Conditions Influencing Health Status
Effects of Probiotics in Immune System of Healthy Adults
The present report describes the design of a clinical trial performed on healthy adult individuals to check whether the daily intake of the new Hero strains contribute to intestinal colonization, under safe and tolerable…
- Trial name
- SETOPROB (NCT01479543)
- Testing
- Probiotic CNCM I-4034, Probiotic CNCM I-4035, Probiotic CNCM I-4036
- Where
- 4 sites in Spain
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Hero Institute for Infant Nutrition
Upper GI Bleeding
Detection of Upper Gastrointestinal (GI) Bleeding With a Novel Bleeding Sensor Capsule [DING]
The clinical trial entitled "Detection of upper gastrointestinal (GI) bleeding with a novel bleeding sensor capsule - a pilot study" was carried out in a monocentric clinical trial with 30 patients.
- Trial name
- DING (NCT03176407)
- Testing
- HemoPill acute
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Ovesco Endoscopy AG
HIV Infection, Gastrointestinal Symptoms
A Controlled Trial to Evaluate the Effects of GanedenBC30 on the Immune System
Improvement in the rate of bacterial translocation may lead to a decrease in a chronic inflammatory response thereby decreasing CD4 destruction and HIV proliferation.
- Trial name
- NCT01184456
- Testing
- GanedenBC30, GBI-30, PTA-6086
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- AIDS Healthcare Foundation
Renal Transplant
Enteric-Coated Mycophenolate Sodium on Quality of Life in Patients With Gastrointestinal Symptoms Related to Mycophenolate Mofetil Therapy After Kidney Transplantation
This open, multi-center randomized controlled study is designed to investigate the quality of life in patients with mycophenolate mofetil (MMF)-induced gastrointestinal (GI) adverse events after converting to enteric-coated…
- Trial name
- NCT00239005
- Testing
- Enteric-Coated Mycophenolate Sodium (EC-MPS), Mycophenolate Mofetil (MMF)
- Where
- United Kingdom
- Volunteers
- 134 people
- Sponsor
- Novartis Pharmaceuticals
Cystic Fibrosis
Multicenter Study of Patient-reported Gastrointestinal Symptoms in People With Cystic Fibrosis
This is a prospective, multicenter, observational study designed to collect gastrointestinal related data in patients with Cystic Fibrosis (CF).
- Trial name
- GALAXY (NCT03801993)
- Where
- 26 sites in United States
- Volunteers
- 402 people
- Sponsor
- Chris Goss
Upper Gastrointestinal Bleeding
Randomized Control Trial Comparing Prokinetics and Their Influence on Endoscopy Outcomes for Upper GI Bleed.
This is a study comparing the effect of erythromycin or metoclopramide, 2 prokinetic drugs (Drugs which are known to speed up the emptying of the stomach or in other words to move the blood out of the stomach faster) given before…
- Trial name
- NCT02017379
- Testing
- Erythromycin, Metoclopromide
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Depression, Fatigue
Programs To Support You During Chemotherapy
This randomized pilot trial studies how well two supportive programs work for improving fatigue and depressive symptoms in patients with GI undergoing chemotherapy.
- Conditions
- Depression, Fatigue, Stage IIA Colorectal Cancer, Stage IIB Colorectal Cancer
- Trial name
- PRO-YOU (NCT02489422)
- Testing
- Laboratory Biomarker Analysis, Questionnaire Administration, Daily Survey Administration
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Wake Forest University Health Sciences
Celiac Disease
Rifaximin for the Treatment of Persistent Symptoms in Patients With Celiac Disease
Celiac disease is a condition in which the small intestine is damaged by gluten, the storage protein of wheat and similar proteins in barley and rye.
- Trial name
- NCT01137955
- Testing
- Rifaximin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Dyspepsia, Diabetes Mellitus With Gastrointestinal Symptoms
Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus
The purpose of this study is to understand why people with indigestion have gastrointestinal symptoms and in particular to understand whether symptoms are related to increased sensitivity to nutrients in the small intestine and…
- Trial name
- NCT02170870
- Testing
- Exendin 9-39, Microlipid
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic