Clinical trials: GYN Disorders
Benign Gynecological Disease
Laparoscopic vs Vaginal Hysterectomy for Benign Gynaecological Disease
This study is designed to compare laparoscopic and vaginal hysterectomy in women with benign gynaecological disease in Ain Shams University Maternity Hospital.
- Trial name
- NCT03692832
- Testing
- LH, VH
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Gynecologic Diseases
Effective Maneuver for Post-laparoscopic Shoulder Pain
The aim of this clinical trial is to estimate the efficacy and safety of combined intervention with the intra-peritoneal normal saline instillation and pulmonary recruitment maneuver for reducing post-laparoscopic shoulder pain.
- Trial name
- NCT02811081
- Testing
- Passive Deflation, Normal Saline Instillation, Normal Saline Instillation + Pulmonary Recruitment
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Kangbuk Samsung Hospital
Gynecologic Disease, Surgery-Complications
New Surgical Approach in Labioplasty
The data of patients who underwent labiaplasty + vaginoplasty between 2020 and 2022 by a single surgeon in our clinic were analyzed.
- Trial name
- NCT05988151
- Testing
- New surgical approach
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Batman Training and Research Hospital
Time Between Hysterectomy and Resumption of Sexual Relations, Sexual Function
Impact of Time on Sexual Function (FSFI® Score) After Hysterectomy
In France, more than 62 000 hysterectomies are performed each year. Female sexual function is the result of multiple psychological, social and physiological factors.
- Trial name
- ISHYS (NCT05728281)
- Testing
- Recommended time after hysterectomy
- Where
- France
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Postoperative Pain, Gynecologic Disease
Additive Effect of Intravenous Acetaminophen on Postoperative Pain Control
This study aimed to evaluate the additive effect of acetaminophen on postoperative pain control in patients receiving nefopam and fentanyl-based patient-controlled analgesia.
- Trial name
- NCT03644147
- Testing
- Acetaminophen
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Seoul National University Hospital
Enhanced Recovery After Surgery, Gynecologic Disease
ERAS in Pediatric & Adolescent Gynecology Preoperative Counseling
The Investigator propose a randomized trial that will assess whether participant involvement in pre-operative counseling for ERAS improves post-surgical pain scores.
- Trial name
- NCT04963751
- Testing
- Enhanced Recovery After Surgery (ERAS) Counseling to Patients, Enhanced Recovery After Surgery (ERAS) Counseling to Caregiver
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Gynecological Disease
The Effectiveness of a Virtual Reality-based Multisensory Intervention
This study explores the effectiveness of a virtual reality-based multisensory intervention for postoperative recovery in patients receiving gynecological surgery.
- Trial name
- NCT06922838
- Testing
- Virtual Reality intervention, Aromatherapy
- Volunteers
- 100 people
- Sponsor
- Weifang Medical University
Gynecologic Diseases
Ultrasonic Versus Monopolar Energy-based Surgical Device in Colpotomy
The aim of this randomized trial was to compare the degree of surgical smoke obstructing vision and thermal damage caused by two different ESDs (ultrasonic versus monopolar ESD) in colpotomy during total laparoscopic hysterectomy.
- Trial name
- ULMOST (NCT02729272)
- Testing
- Laparoscopic colpotomy by ultrasonic ESD, Laparoscopic colpotomy by monopolar ESD, Monopolar ESD
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Kangbuk Samsung Hospital
Vaginal Disease
Study of the Vaginal Microbiota in Women Under Fertile Age
Characterization of the vaginal microbiota of women under fertile age and study of correlations with gynecological disorders
- Trial name
- vaginalbiota (NCT05817292)
- Testing
- Probiotics, No intervention
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Catania
Educational Problems, Surgery
Standardized Educational Videos of Laparoscopic Gynecological Surgeries
Owing to coronavirus disease-related social distancing requirements, online education has gained prominence. Surgical trainers consider online videos as a useful teaching aid that maximizes trainees' learning and skill…
- Conditions
- Educational Problems, Surgery, LAP, GYN Disorders
- Trial name
- AA-GYNLAP (NCT05227430)
- Testing
- Educational video tutorials
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Insomnia
Feasibility of Internet Group CBT-I for Gyn Oncology Patients
The goal of this study is to evaluate the feasibility and acceptability of delivering cognitive behavioral therapy for insomnia (CBT-I) to gynecologic cancer patients in an internet-based small-group setting.
- Trial name
- NCT06060158
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of California, Davis
Women With Suspected or Confirmed Gynecological Disease
DOvEEgene Fleur: New Uterine Sampling Tool
This study is related to a previous study from the same group which started in 2014 (NTC02288676, McGill REB A08-M79-13B, MUHC REB 2020-5945) to develop a clinically implementable screening test -DovEEgene: developing and…
- Trial name
- NCT04258449
- Testing
- DOvEEgene Fleur Sampling
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McGill University
Gynecologic Disease, Endometriosis
Ultrasound Evaluation of the Pelvis in Women with Suspected Endometriosis Scheduled for Laparoscopic Surgery
An international multicenter observation study to evaluate the diagnostic accuracy and predictive value of ultrasound using the IDEA terminology in the detection of deep endometriosis in women scheduled for surgery.
- Conditions
- Gynecologic Disease, Endometriosis, Endometriosis, Rectum, Endometriosis of Colon
- Trial name
- IDEA1 (NCT04171297)
- Testing
- Ultrasound evaluation of DE
- Where
- 3 sites in Australia, Belgium and 1 more
- Volunteers
- 1,866 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gynecologic Nursing, Training Group, Sensitivity
Improving Gynecological Examination Skills with the Use of a Model
Vaginal, abdominal, and breast examinations are among the essential gynecological examination skills for midwifery students and are crucial steps that need to be learned.
- Conditions
- Gynecologic Nursing, Training Group, Sensitivity, Gynecologic Disease
- Trial name
- NCT06536192
- Testing
- Model group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Urinary Retention
Optimal Management of Urinary Catheter in Gyn Onc
This is a combined retrospective observational study that will collect data on urinary catheter removal of patients who underwent pelvic surgery by a gynecologic oncologist to assess timing safety and its implications in…
- Trial name
- NCT05538273
- Testing
- Early removal of urinary catheter postoperatively, Late removal of urinary catheter postoperatively
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- WellSpan Health
Esophageal Diseases, Gastrointestinal Diseases
Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy
The purpose of this study is to determine whether the early identification and more precise intervention of operating room (OR) patient fluid administration optimization using arterial pressure-based cardiac output (APCO) yields…
- Conditions
- Esophageal Diseases, Gastrointestinal Diseases, Disorder of the Genitourinary System, Gynecologic Diseases
- Trial name
- NCT00526331
- Testing
- Vigileo Monitor, FloTrac Sensor
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- M.D. Anderson Cancer Center
Uterine Diseases
Hysterectomy by Transabdominal Laparoscopy or NOTES
Objective: To randomly compare hysterectomy by vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) versus laparoscopy uterus in women with benign gynecological pathology.
- Trial name
- HALON (NCT02631837)
- Testing
- vNOTES hysterectomy, LSC hysterectomy
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Imelda Hospital, Bonheiden
Infertility, Female, Recurrent Miscarriage
Immune Cell Populations in the Endometrium
Specialized immunological studies in the diagnostics of idiopathic infertility and recurrent miscarriages have limited applicability, as the role of the immune system in these conditions is not thoroughly understood.
- Conditions
- Infertility, Female, Recurrent Miscarriage, Gynecologic Disease
- Trial name
- NCT06826365
- Testing
- Percentage distribution of immune system cells in peripheral blood, Percentage distribution of immune system cells in endometrium
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Jagiellonian University
Urinary Tract Infections (UTIs)
Evaluation of the Effectiveness and Safety of a Vaginal Gel for Prevention of Recurrent Urinary Tract Infections
Urinary Tract Infections (UTIs) are among the most common bacterial infections. Although they are typically treated effectively with antibiotics, recurrence is a frequent and troublesome issue.
- Trial name
- UTI (NCT07233473)
- Testing
- Multi-Gyn UT Protect gel
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Karo Pharma AB
Epithelial Ovarian Cancer, Extraovarian Peritoneal Cancer
A Trial of Intravenous Denileukin Diftitox in Stage III or IV Ovarian Cancer
This study tests whether denileukin diftitox will deplete regulatory T cells, boost tumor-specific immunity and treat epithelial ovarian cancer in patients who have failed, or who are ineligible for front line therapy.
- Conditions
- Epithelial Ovarian Cancer, Extraovarian Peritoneal Cancer, Fallopian Tube Carcinoma
- Trial name
- ONTAK (NCT00880360)
- Testing
- Ontak
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- The University of Texas Health Science Center at San Antonio