Clinical trials: Gait Disorders, Neurologic
Parkinson Disease
Deep Brain Stimulation of the Cuneiform Nucleus for Levodopa-resistant Freezing of Gait in Parkinson's Disease
The purpose of this research study is to determine if DBS is a safe and effective therapy for severe freezing of gait in patients with Parkinson's Disease.
- Trial name
- DBS + FOG (NCT04218526)
- Testing
- Vercise DBS System
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Jonathan Jagid
Cerebral Palsy
Efficacy of a Rehabilitation Program With the Pediatric Exoskeleton ATLAS 2030 in Pediatric Patients With Cerebral Palsy
Cerebral Palsy (CP) is the first cause of motor disability in children worldwide. ATLAS 2030 is a robotic gait exoskeleton designed to rehabilitate children with motor disability.
- Trial name
- NCT05926635
- Testing
- ATLAS 2030
- Where
- 5 sites in Spain
- Volunteers
- 60 people
- Sponsor
- MarsiBionics
Neurodegenerative Diseases, Parkinson Disease
Neurodegenerative Diseases Progression Markers (MARKERS-NDD)
MARKERS-NDD is a prospective, observational, longitudinal study, which aims to collect data from patients affected by neurodegenerative diseases (NDD) followed longitudinally for routine examinations performed as part of normal…
- Conditions
- Neurodegenerative Diseases, Parkinson Disease, Synucleinopathies, Lewy Body Disease
- Trial name
- MARKERS-NDD (NCT06596746)
- Testing
- Observation
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Casa di Cura San Raffaele Cassino
Adolescent Idiopathic Scoliosis, Gait Disorder, Sensorimotor
The Effect of Conservative Treatment on Gait Biomechanics in Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional complex progressive structural deformity of the growing spine. Asymmetric changes in both the anatomical structure and strength of the muscles due to deformity affect…
- Trial name
- NCT05577546
- Testing
- Moor S brace treatment, Schroth Three-Dimensional Scoliosis Exercise Treatment
- Where
- Slovenia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medipol University
Balance Problems, Cerebral Palsy
Independent Walking Speed and Crossing a City Street
The purpose of this study is to determine if selected sequence training using the Balance Master, added to established physical therapy treatment programs, will increase gait velocity of ambulatory children receiving inpatient or…
- Trial name
- NCT02842398
- Testing
- Balance Master, Customary Care
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Blythedale Children's Hospital
Stroke, Osteoporosis
Sarcopenia and Risk of Falls in Patients With Major Chronic Diseases
The objective of this study is to investigate the effects of therapeutic exercise and nutrition intervention for sarcopenia and risk of falls in patients with major chronic diseases.
- Conditions
- Stroke, Osteoporosis, Chronic Kidney Diseases, Cancer
- Trial name
- NCT03798418
- Testing
- elastic band strengthening exercise, diet counseling
- Where
- Taiwan
- Volunteers
- 186 people
- Sponsor
- Changhua Christian Hospital
Parkinson Disease, Gait, Unsteady
Effect of Haptic Cueing on Long-Range Autocorrelations in Parkinson's Disease Gait Variability
Parkinson's Disease (PD) patients suffer from gait impairments responsible for falls and bad quality of life: reduced speed and stride length, randomness in the temporal organization of stride duration variability (reduced…
- Trial name
- NCT05790759
- Testing
- No cueing versus Haptic cueing versus Auditory cueing during parkinson's disease gait
- Where
- 2 sites in Belgium
- Volunteers
- 10 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Spinal Cord Injury
Combining tsDCS and Exoskeleton Gait Training on Spinal Excitability in SCI
The purpose of the study is to determine whether transcutaneous spinal direct current stimulation (tsDCS) is safe for individuals with spinal cord injury (SCI). tsDCS is an electrical current applied to the skin.
- Trial name
- NCT02862080
- Testing
- cathode tsDCS, Ekso, anode tsDCS
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Parkinson Disease, Gait Disorders, Neurologic
Automated Mechanical Peripheral Stimulation to Treat Freezing of Gait in Patients With Parkinson's Disease and STN-DBS
The objective is to investigate whether AMPS (Automated Mechanical Peripheral Stimulation) is effective in reduction of FOG measured via the FOG-AC (Freezing Of Gait Assessment Course) in people with Parkinson Disease and STN-DBS…
- Trial name
- AMBITION (NCT04831879)
- Testing
- GONDOLA AMPS
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Gondola Medical Technologies SA
Multiple Sclerosis
High-Intensity, Dynamic-stability Gait Training in People With Multiple Sclerosis
The goal of this clinical trial is to improve walking speed, balance, and walking in the community for people with multiple sclerosis. This trial involves intense exercise combined with walking on a shaky treadmill.
- Trial name
- NCT05735691
- Testing
- High-Intensity Treadmill Training, Treadmill Training with Perturbations, Standard Treadmill Training
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Marquette University
Stroke
Effect of Robot-assisted Gait Training on Brain Reorganization in Hemiplegic Patients
Purpose: To evaluate the effect of robotic gait therapy for brain reorganization in hemiplegia patients.
- Trial name
- NCT02569190
- Testing
- Walkbot
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Veterans Health Service Medical Center, Seoul, Korea
Stroke, Spasticity
Early Injection of Botulinum Toxin on Motor Function and Gait Pattern in Stroke Patients
Spasticity, muscle weakness, abnormal gait pattern are co-morbidities commonly seen in stroke patients. They cause disabled condition of patients in activities of daily life and functional performance, and also accidental falls…
- Trial name
- NCT01817816
- Testing
- Botox_A, Botox_B
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Changhua Christian Hospital
Multiple Sclerosis Relapse
Role of Virtual Reality in MS Rehabilitation
Objective: To investigate the role of virtual reality (VR) paired with robotic-assisted gait training (RAGT) compared with RAGT alone in patients with Multiple Sclerosis (MS).
- Trial name
- NCT02834533
- Testing
- Lokomat
- Volunteers
- 40 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Gait Disorders, Neurologic, Parkinson Disease
Individualization of Music-based Cueing During Gait in Parkinson's Disease.
Spatio-temporal correction of the step is a key component of gait rehabilitation in Parkinson's disease. Walking rehabilitation techniques using visual or auditory cueing of the cadence or step length have been tested to prevent…
- Trial name
- MUSIGAIT (NCT05585489)
- Testing
- Gait training with musical cue
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Henri Mondor University Hospital
Diabetes, Cancer
Exploring the Effectiveness of Sensor-based Balance Training on Patient Outcome Measures
Explore the benefit of the game-based virtual reality system in improving lower extremity kinematics and balance in patients suffering from disease/disorders including Diabetes, Cancer, Multiple Sclerosis, Arthritis, Parkinson's…
- Conditions
- Diabetes, Cancer, Multiple Sclerosis, Arthritis
- Trial name
- NCT02777060
- Testing
- Exergame, Home based balance training
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Arizona
Hip Fractures, Gait, Unsteady
Comparison of Sliding Hip Screw to Intra Medullary Nailing in the Treatment of Intertrochanteric Hip Fracture
Shortening of the abductor lever arm is a particular concern with the SHS, and the resultant biomechanical alterations may impair gait, including decreased cadence, gait speed and increased double support time on the injured…
- Conditions
- Hip Fractures, Gait, Unsteady, Function
- Trial name
- NCT03906032
- Testing
- TFNA IM Nail, Sliding hip screw
- Where
- Ireland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Waterford
Parkinson Disease
Investigation of the Effects of LSVT-BlG Protocol on Balance, Gait, Fatigue and Quality of Life in Parkinson's Patients
Parkinson's disease is a progressive, degenerative neurological disease manifested by motor and non-motor symptoms. Treatment for Parkinson's disease is symptom-oriented.
- Trial name
- NCT06215898
- Testing
- LSVT-BIG Group via Telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Izmir Bakircay University
Parkinson Disease
Deep Brain Stimulation (DBS) Frequency Effects on Gait in Parkinson's Disease(PD)
In this study the investigators will evaluate the effect of both low and high frequency Deep Brain stimulation of the subthalamic nucleus (STN) in Parkinson's patients who have noted a change in their walking.
- Trial name
- NCT00993291
- Testing
- Frequency change to 60 Hz, Frequency change to 130 Hz
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vanderbilt University
Parkinson Disease, Gait Disorders, Neurologic
Investigating Neural Biomarkers for Gait in Parkinson's Patients
This observational study's main goal is to learn more about the neural mechanisms during movement in Parkinson's disease. Furthermore, it aims to inspire personalised treatment options.
- Trial name
- NCT05820074
- Testing
- Neural Activity Recording, Movement Parameter Recording, Neuromodulation
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Stroke
Effect of FES of Back Muscles on Spinal Posture and Gait in Hemiplegia
Hemiplegic patient have unbalanced posture because paralysis leads to muscle atrophy, which then causes an unbalanced alignment in the structure of spinal joints.
- Trial name
- NCT05473390
- Testing
- functional electrical stimulation, kinesotaping
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University