Clinical trials: Gait Disorders
Parkinson Disease
Safety and Efficacy of State-of-the-Art Exoskeleton Technology to Improve Mobility in Parkinson's Disease
The purpose of this study is to test the safety and efficacy of using of a portable exoskeleton for walking training in persons with Parkinson's disease that have gait mobility problems and/or postural instability.
- Trial name
- NCT04587193
- Testing
- Robotic-assist gait training device
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Virginia Commonwealth University
Cerebral Palsy, Hemiplegic Cerebral Palsy
Dynamic Gait Index in Hemiplegic Cerebral Palsy
The purpose of this study is to assess validity and reliability of Dynamic Gait Index (DGI) in patients with unilateral spastic cerebral palsy
- Conditions
- Cerebral Palsy, Hemiplegic Cerebral Palsy, Gait Disorders, Neurologic
- Trial name
- NCT03662139
- Testing
- Dynamic Gait Index
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Marmara University
Diabetes Mellitus, Leg Injuries
Prosthetic Components and Stability in Amputee Gait
The biomechanics of changing direction while walking has been largely neglected despite its relevancy to functional mobility. In addition, an increased risk of injury can be associated with turning due to a decrease in stability.
- Conditions
- Diabetes Mellitus, Leg Injuries, Traumatic Amputation
- Trial name
- NCT00167778
- Testing
- Transverse plane rotation adaptor pylon, Rigid pylon
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Stroke, Acute Stroke
Soft Exosuits for Functional Gait Recovery in Acute Stroke Rehabilitation
The purpose of this study is to develop and evaluate the use of soft exosuits in patients post stroke.
- Trial name
- NCT06231511
- Testing
- Hip flexion soft exosuit, ReWalk ReStore soft exosuit, Conventional physical therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Shirley Ryan AbilityLab
Foot Drop, Acute Lymphoblastic Leukemia
The Effects of Ankle Foot Orthoses on Gait Efficiency in Children With Acute Lymphoblastic Leukemia and Foot Drop
This study is designed to see if children with acute lymphoblastic leukemia who have developed foot drop during treatment for their leukemia consume less oxygen when walking with or without an ankle brace designed to support…
- Trial name
- NCT01001390
- Testing
- AFO Device
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- St. Jude Children's Research Hospital
Equinovarus; Acquired
Assessment of Gait After Dysport Treatment
This pilot study will aim to understand the potential benefit of the assessment of walking using video slow motion for muscle selection and the development of an image catalogue guide of the potential results of injection of…
- Trial name
- NCT03501043
- Testing
- Dysport
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Albert Einstein Healthcare Network
Parkinson Disease With Freezing of Gait
Effects of Neuromodulation and Rehabilitation of the Locomotor Network in Freezing of Gait
Freezing of gait (FoG) is a common and debilitating condition in Parkinson's Disease (PD) patients. FoG is described as an episodic inability to walk, which often triggers falls, hospitalization and is an important predictor of…
- Trial name
- TMS/FOG (NCT03273270)
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Parkinson Disease
Varenicline for Gait and Balance Impairment in Parkinson Disease
The purpose of this study is to determine if varenicline is effective in improving gait and balance impairment in patients with Parkinson disease.
- Trial name
- Chantix-PD (NCT01341080)
- Testing
- Varenicline, Sugar pill
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rush University Medical Center
Parkinson Disease, DBS
Utilizing Neural Signatures and Virtual Reality to Advance DBS Programming
The project uses virtual reality technology to recreate situations that cause freezing of gait in individuals with Parkinson's disease.
- Conditions
- Parkinson Disease, DBS, Deep Brain Stimulation, Freezing of Gait
- Trial name
- NCT05103384
- Testing
- Virtual Reality Environment
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The Cleveland Clinic
Knee Injuries, Knee Osteoarthritis
Gait Modification Treatments for Knee Pathology
The objective of this study is complete a longitudinal cross-over clinical study to investigate the effect of treatments for knee pathology, including cutaneous stimulation (skin vibration and soft knee brace), on locomotion…
- Trial name
- NCT03116230
- Testing
- Cutaneous Stimulation, Knee Sleeve
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Stanford University
Postacute Sequelae of Sars-CoV-2, Post-Acute COVID-19 Syndrome
Transcutaneous Electrical Nerve Stimulation (TENS) in Patients With Postacute Sequelae of Sars-CoV-2
The purpose of the pilot study is to examine acceptability and proof of concept effectiveness of a wireless TENS technology to address PASC associated FM.
- Conditions
- Postacute Sequelae of Sars-CoV-2, Post-Acute COVID-19 Syndrome, Widespread Chronic Pain, Fatigue Syndrome, Chronic
- Trial name
- NCT05200858
- Testing
- TENS - high-dose, TENS - low-dose
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
Parkinson
Prism Adaptation Treatment of Parkinson's Disease
Subjects diagnosed with Idiopathic Parkinson's Disease, between ages of 40-85 inclusive, who have been referred for gait training.
- Trial name
- NCT02380859
- Testing
- Prism adaptation
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Frailty, Sarcopenia
FrAilty Care and wEll-funcTion in Community Dwelling Older Adults
This study is looking at whether older people could benefit from an online monitoring platform to support their individual ambitions to maintain or improve functional ability.
- Conditions
- Frailty, Sarcopenia, Aging
- Trial name
- FACET (NCT03707145)
- Testing
- Consultation, Online Support, Empowered
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Aberystwyth University
Mild Cognitive Impairment, Cognitive Decline
Effects of Walkasins on Gait Speed of Individuals With Mild Cognitive Impairments
The primary aim of this pilot study is to investigate the effect of Walkasins, a wearable lower-limb sensory prosthesis, on the gait speed and balance function of participants with mild cognitive impairment as measured by the…
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Gait Disorders in Old Age
- Trial name
- NCT05723822
- Testing
- Walkasins
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- RxFunction Inc.
Stroke, CVA
Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke.
PURPOSE: The purpose of this study will be to identify whether patients in the subacute stage of stroke, who demonstrate foot drop, will have better gait outcomes when using a Double Adjustable AFO, or a Posterior Leaf Spring…
- Conditions
- Stroke, CVA, Hemiplegia, Hemiparesis
- Trial name
- NCT02693834
- Testing
- Posterior Leaf spring AFO, Double adjustable AFO
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Texas Woman's University
Stroke
Sensory Augmentation Methods in Stroke
Many chronic stroke survivors have poor walking balance, contributing to an increased risk of falls and fear of falling. One factor contributing to these balance deficits is a reduced ability to place the feet appropriately when…
- Trial name
- SAM (NCT03988400)
- Testing
- Sensory Augmentation, Random Vibration
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- VA Office of Research and Development
Stroke, Gait, Hemiplegic
Effect of Structured Progressive Task-Oriented Circuit Class Training With Motor Imagery on Gait in Stroke
The objectives of the study will be General Objective is to investigate the effect of TOCCT with MI on gait performance in patients with stroke. Speific Objevtives.
- Trial name
- NCT03436810
- Testing
- Motor imagery, Health education, Task-Oriented Circuit Class Training
- Where
- Burma
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Depression, Cognitive Impairment
1/2-Dopaminergic Dysfunction in Late-Life Depression (The D3 Study)
Growing evidence suggests that dopamine contributes to key cognitive, emotional, and motor functions across the lifespan. In Late-Life Depression (LLD), dysfunction in these areas is common, predicts poor outcomes, and manifests…
- Conditions
- Depression, Cognitive Impairment, Gait Impairment
- Trial name
- NCT04493320
- Testing
- Carbidopa/levodopa
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Spinal Cord Injuries
Improving Gait Performance in Individuals With Spinal Cord Injuries: an Intervention Using Robotic Exoskeletons
The purpose of this study is to investigate whether robotic exoskeleton training can improve walking performance after SCI as compared to conventional physical therapy.
- Trial name
- NCT03011099
- Testing
- Robotic exoskeleton training, Conventional physical therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center, Houston
Parkinson's Disease
Deep Brain Stimulation Effects on Gait and Balance in Patients With Parkinson's Disease
The purpose of this study is to evaluate the effect of Deep Brain stimulation (DBS) on walking in patients with Parkinson's disease that have had DBS.
- Trial name
- NCT02022735
- Testing
- Deep Brain Stimulator
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Miami