Clinical trials: Gait Dysfunction
Mild Cognitive Impairment (MCI), Depressive Symptoms
rTMS Combined With Aerobic Exercise for Older Adults With Mild Cognitive Impairment and Comorbid Depression
This study aims to evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) and aerobic exercise on cognitive function and mental health in older adults with mild cognitive impairment (MCI) and comorbid…
- Trial name
- NCT07652775
- Testing
- Repetitive Transcranial Magnetic Stimulation, Aerobic Exercise
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Cheng-Hsin General Hospital
Multiple Sclerosis, Balance
Technological Balance and Gait Rehabilitation in Patients With Multiple Sclerosis.
Multiple sclerosis (MS) is a chronic, inflammatory and neurodegenerative disease of the central nervous system that often results in motor and/or cognitive impairment.
- Conditions
- Multiple Sclerosis, Balance, Cognitive Impairment
- Trial name
- ROAR-MS (NCT05983809)
- Testing
- Technological rehabilitation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
PD, Gait Dysfunction, Neurologic
Effectiveness of Different Approaches for the Rehabilitation of Gait in Patients With Parkinson's Disease
Evaluation of the effectiveness of three different approaches for the rehabilitation of gait in patients with PD within a multidisciplinary, intensive rehabilitation treatment (MIRT).
- Conditions
- PD, Gait Dysfunction, Neurologic, Rehabilitation
- Trial name
- Tr-T-VR (NCT03021408)
- Testing
- MIRT + Treadmill, MIRT + Treadmill Plus, MIRT + Virtual Reality
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Mild Cognitive Impairment, Gait
Association of Perceived Occupational Performance and Satisfaction, Balance, Gait, and Fear of Falling in Older Adult With Mild Cognitive Impairment
This study was designed to investigate the occupational performance and balance, gait, and fear of falling in older adults with MCI.
- Conditions
- Mild Cognitive Impairment, Gait, Balance, Occupational Problems
- Trial name
- NCT06513325
- Testing
- Canadian Occupational Performance Measure
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gulhane School of Medicine
Neurodegenerative Diseases, Parkinson Disease
Neurodegenerative Diseases Progression Markers (MARKERS-NDD)
MARKERS-NDD is a prospective, observational, longitudinal study, which aims to collect data from patients affected by neurodegenerative diseases (NDD) followed longitudinally for routine examinations performed as part of normal…
- Conditions
- Neurodegenerative Diseases, Parkinson Disease, Synucleinopathies, Lewy Body Disease
- Trial name
- MARKERS-NDD (NCT06596746)
- Testing
- Observation
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Casa di Cura San Raffaele Cassino
Stroke, Ischemic, Transient Ischemic Attack
Pathophysiology and Risk of Atrial Fibrillation Detected After Ischemic Stroke
This prospective non-interventional cohort study investigates the pathophysiology of Atrial Fibrillation Detected After Stroke or transient ischemic attack (AFDAS) by comparing the autonomic function and inflammation between…
- Conditions
- Stroke, Ischemic, Transient Ischemic Attack, Atrial Fibrillation
- Trial name
- PARADISE (NCT03275155)
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Mild Cognitive Impairment
Dual Task Training in Elderly Using the BioRescue
Mild cognitive impairment (MCI) is accompanied by gait and balance problems while dual tasking. During a 6 to 8 weeks training with the BioRescue (virtual reality), institutionalized elderly people with MCI will relearn dual…
- Trial name
- NCT02681354
- Testing
- Biorescue training
- Where
- 2 sites in Belgium
- Volunteers
- 21 people
- Sponsor
- Hasselt University
Mild Cognitive Impairment, Mild Dementia
Gait Analysis by Induced Disorientation in a VR Environment
The aim of the study is to investigate whether the effect of disorientation on physical motion and gait among dementia patients, can be reliably measured in a laboratory environment, by means of a virtual reality (VR)…
- Conditions
- Mild Cognitive Impairment, Mild Dementia, Disorientation, Young Adults
- Trial name
- NCT04134806
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Medical Center Rostock
Hip Fracture, Geriatrics
Clinical Efficacy of Exoskeleton Robot-Assisted Rehabilitation on Lower Limb Functional Recovery in Elderly Patients With Hip Fracture
With the intensification of population aging, hip fracture, as a common bone disease, is seeing an increasing incidence rate among the elderly population.
- Conditions
- Hip Fracture, Geriatrics, Lower Extremity Dysfunction, Postoperative Rehabilitation
- Trial name
- NCT07323147
- Testing
- Exoskeleton, Conventional rehabilitation program
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Hai bao
Knee Arthroscopy, Knee Arthroplasty
Investigating the Efficacy of Osteopathic Manipulative Treatment on Gait Dysfunction Following Knee Surgery
For patients with a history of knee surgery, especially knee arthroplasty, the persistence of abnormal gait kinematics is a frequently encountered issue that can hinder their ability to return to normal daily living.
- Conditions
- Knee Arthroscopy, Knee Arthroplasty, Osteopathic Manipulative Treatment, Gait, Unsteady
- Trial name
- NCT05580640
- Testing
- OMT
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Midwestern University
Parkinson Disease
Varenicline for Gait and Balance Impairment in Parkinson Disease
The purpose of this study is to determine if varenicline is effective in improving gait and balance impairment in patients with Parkinson disease.
- Trial name
- Chantix-PD (NCT01341080)
- Testing
- Varenicline, Sugar pill
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rush University Medical Center
Mild Cognitive Impairment
Maze Activities' Impact on Balance and Gait in Cognitively Impaired Children
This study aims to evaluate the effect of the Minds in Motion Maze program on balance and gait in children with cognitive impairment. It focuses on how movement-based, sensory-integrated activities can improve motor performance.
- Trial name
- NCT07729865
- Testing
- mind in motion maze activity, baseline activities
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Parkinson's Disease
Subthalamic Nucleus, Akinesia and Parkinson's Disease
This program aims to understand the role of the subthalamic nucleus in the control of the movement in healthy humans and patients with Parkinson's disease, how the STN dysfunction contributes to akinesia and how the STN…
- Trial name
- GB-MOV (NCT01682668)
- Testing
- Bilateral subthalamic stimulation
- Where
- 2 sites in France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Mild Cognitive Impairment, Cognitive Decline
Effects of Walkasins on Gait Speed of Individuals With Mild Cognitive Impairments
The primary aim of this pilot study is to investigate the effect of Walkasins, a wearable lower-limb sensory prosthesis, on the gait speed and balance function of participants with mild cognitive impairment as measured by the…
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Gait Disorders in Old Age
- Trial name
- NCT05723822
- Testing
- Walkasins
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- RxFunction Inc.
Depression, Cognitive Impairment
1/2-Dopaminergic Dysfunction in Late-Life Depression (The D3 Study)
Growing evidence suggests that dopamine contributes to key cognitive, emotional, and motor functions across the lifespan. In Late-Life Depression (LLD), dysfunction in these areas is common, predicts poor outcomes, and manifests…
- Conditions
- Depression, Cognitive Impairment, Gait Impairment
- Trial name
- NCT04493320
- Testing
- Carbidopa/levodopa
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Aging, Pain, Acute
Effects of Acute Pain on Motor Learning in Young vs Older Adults
To date, the effects of pain on motor learning have not been thoroughly investigated, particularly in older adults. Broadly, the purpose of this research is to investigate the impact of acute pain on locomotor learning and its…
- Conditions
- Aging, Pain, Acute, Cognitive Decline, Motor Activity
- Trial name
- NCT05471557
- Testing
- pain delivery
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Mild Cognitive Impairment (MCI)
Cognitive-Frailty Gait Biomechanics for Early Dementia Detection
The purpose of this study is to better understand how physical characteristics, walking patterns, and a blood-based brain health marker differ between older adults with dementia and healthy older adults.
- Trial name
- gait dementia (NCT07448909)
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Executive Dysfunction, Gait Performance
Improving Mobility and Cognition in Older Adults Using Non-Invasive Brain Stimulation
This study aims to test the efficacy of a type of non-invasive brain stimulation (NIBS), known as repetitive transcranial magnetic (rTMS) stimulation, in improving mobility, particularly gait stability and variability, and…
- Conditions
- Executive Dysfunction, Gait Performance, Repetitive Transcranial Magnetic Stimulation
- Trial name
- NIBS (NCT02740530)
- Testing
- Magstim® Rapid 2 machine
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Stroke, Walking Impairment
Investigating the Mechanisms of Welwalk Robot in Restoring Motor Function of the Lower Extremities in Stroke Patients
Current evidence and clinical applications of robotic gait training devices for motor function recovery post-stroke are increasingly available.
- Trial name
- NCT07057700
- Testing
- welwalk training, physical therapy
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Ruijin Hospital
Amputation, Neuropathy;Peripheral
Kinetic Analysis Due to Foot Dysfunction
The aim of the current study is to examine the biomechanical changes of gait kinetics in patients with either partial foot amputation or peripheral neuropathy
- Trial name
- NCT05161364
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Delta University for Science and Technology