Clinical trials: Gall Stone Disease
Sphincter of Oddi Function
Endoclip Papillaplasty Recover Sphincter of Oddi Function After Endoscopic Sphincterotomy for Bile Duct Gallstones
Gallstones in the common bile duct (CBD) may be asymptomatic but may lead to complications such as acute cholangitis or acute pancreatitis. EST is widely used for the treatment of bile duct gallstones.
- Trial name
- NCT04183036
- Testing
- Endoclip papillaplasty
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Peking University Third Hospital
Gallstones, Cholelithiasis
RCT: Multi-modal Analgesia for Laparoscopic Cholecystectomy
Analgesic efficacy of multi-modal analgesia is superior to standard analgesia for patients undergoing elective laparoscopic cholecystectomy for symptomatic cholelithiasis.
- Conditions
- Gallstones, Cholelithiasis, Pain
- Trial name
- LapChole (NCT01972620)
- Testing
- Bupivacaine
- Where
- Serbia
- Volunteers
- 63 people
- Sponsor
- Klinicki Centar Vojvodine
Cholecystitis; Gallstone, Cholecystolithiasis
Effect of TENS on Patient Outcomes After Laparoscopic Cholecystectomy
The aim of this study is to evaluate the effect of TENS (Transcutaneous Electrical Nerve Stimulation) on patient outcomes after laparoscopic cholecystectomy.
- Trial name
- TENS (NCT05962853)
- Testing
- Experimental group (Transcutaneous Electrical Nerve Stimulation)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Cukurova University
Cholecystitis, Acute, Cholecystitis; Gallstone
Observation vs Early Removal of LAMS in EUS Guided Cholecystoenterostomy
The study will compare the outcomes of patients with gallstone related cholecystitis who are poor surgical candidates undergoing EUS guided cholecystoenterostomy via a lumen apposing metal stent (LAMS).
- Trial name
- NCT04167072
- Testing
- Stent removal
- Where
- United States
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Gallstone
The Discovery of the Double Sphincter in Gallbladder
We found a new Double sphincter which located in the neck of gallbladder，we supposed it may be related to control pressure of bile duct.Its formation is related to genetic factors.
- Trial name
- NCT01998451
- Testing
- Tauroursodeoxycholic acid
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Cholecystitis; Gallstone
Safety of Laparoscopic ChOlecystectomy Performed by Trainee Surgeons With Different CHolangiographic Techniques
Laparoscopic cholecystectomy (LC) gained popularity among general surgeons in 1990s and rapidly become one of the most commonly performed procedures in digestive surgery, with more than one million cholecystectomies being…
- Trial name
- SCOTCH (NCT04863482)
- Testing
- IOC
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Università Politecnica delle Marche
Gallstones
Laparoscopic Cholecystectomy With Retro-infundibular Approach
Aimed to evaluate laparoscopic cholecystectomy by retro-infundibular (RI) approach compared to standard laparoscopic cholecystectomy (SLC) in difficult cases with scarred chole-cystohepatic (Calot's) triangle.
- Trial name
- NCT02947256
- Testing
- standard laparoscopic cholecystectomy, RI approach
- Where
- 2 sites in Egypt
- Volunteers
- 125 people
- Sponsor
- Minia University
Common Bile Duct Calculi
Early Versus Late Laparoscopic Exploration of Common Bile Duct After Failure of Extraction of Common Bile Duct Stones by ERCP
The goal of this work is to assess the best time to perform LC combined with LCBD exploration and the feasibility and safety of such procedure in patients with combined GBS and CBDS after failure of ERCP extraction of CBD stones .
- Trial name
- NCT05823181
- Testing
- laparoscopy
- Volunteers
- 50 people
- Sponsor
- Assiut University
Common Bile Duct Calculi
The Cost Effectiveness of Endoscopic Ultrasound ( EUS ) Based Strategy in Diagnosis of Common Bile Duct Stones
Multiple reports in the literature showed the efficacy of EUS comparable to ERCP in the diagnosis of common bile duct ( CBD ) stone.
- Trial name
- NCT02349568
- Testing
- High risk group, Intermediate risk group
- Where
- Thailand
- Volunteers
- 141 people
- Sponsor
- Prince of Songkla University
Gallstones, Cholelithiasis
Chinese Registry Study on Treatment of Cholecysto-Choledocholithiasis
Patients with gallstone and confirmed common bile duct stones are registered in this study. The three managements for common bile duct stones are endoscopic sphincterotomy (EST), laparoscopic common bile duct exploration (LCBDE)…
- Conditions
- Gallstones, Cholelithiasis, Cholecystolithiasis, Choledocholithiasis
- Trial name
- CREST Choles (NCT02554097)
- Testing
- endoscopic sphincterotomy, laparoscopic common bile duct exploration, laparoscopic transcystic common bile duct exploration
- Where
- China
- Volunteers
- 2,700 people
- Sponsor
- Beijing Friendship Hospital
Common Bile Duct Gall Stones, Common Bile Duct GallStones
Rate of Duodenal-biliary Reflux Increases in Patients With Recurrent Common Bile Duct Stones
ERCP is the primary choice for removal of common bile duct stone (CBDS) currently. However, 4-24% patients underwent recurrence after successful clearance of CBDS.
- Trial name
- NCT02329977
- Testing
- standard barium meal examination
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Air Force Military Medical University, China
Bile Duct; Obstruction, With Calculus, Choledocholithiasis
Clinical Trial Comparing ERCP vs ERCP and Transmural Gall Bladder Drainage
Cholelithiasis occurs in 10-20% of the general population. Up to 18% of these subjects will present symptoms. In patients with symptomatic choledocholithiasis who are not candidates for surgery with indication for ERCP…
- Trial name
- PECAS (NCT03921502)
- Testing
- Gall bladder transmural drainage with LAMS
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital del Rio Hortega
Laparocele
Post-Cholecystectomy Gall Bladder Remnant and Cystic Duct Stump Stone
Introduction: cholecystectomy relieves pre-surgical symptoms of gallbladder disease. The persistence of symptoms was recorded in 10 - 20% of cases. Residual gall bladder/cystic duct stump stone is one of the most important cause.
- Trial name
- NCT04329143
- Testing
- open completion cholecystectomy, lap completion cholecystectomy
- Volunteers
- 2 people
- Sponsor
- Zagazig University
Acute Biliary Pancreatitis
Early EUS in Acute Biliary Pancreatitis
Acute biliary pancreatitis (ABP) is a potentially life-threatening condition caused by common bile duct (CBD) stones or sludge, which requires prompt diagnosis and treatment by endoscopic removal of the material.
- Trial name
- NCT02430285
- Testing
- Endoscopic Ultrasound, Olympus 180 series echoendoscope
- Where
- Italy
- Volunteers
- 181 people
- Sponsor
- Istituto Clinico Humanitas
Gallstone Disease, Gallstone; Colic
A Randomized Controlled Trial Comparing Fat-free Versus Balanced (WHO) Diet in Gallstone Disease
The goal of this trial is to assess the effect on the quality of life (QoL) of recommending a fat-free diet versus a balanced WHO diet in symptomatic patients with gallstones and in patients undergoing cholecystectomy for…
- Conditions
- Gallstone Disease, Gallstone; Colic, Gallstone; Cholecystitis, Acute, Cholelithiases
- Trial name
- RADIGAL (NCT06405906)
- Testing
- Fat-free diet, Balanced WHO diet
- Where
- Greece
- Volunteers
- 242 people
- Sponsor
- University Hospital of Crete
Cholelithiasis, Cholecystitis
Cholecystectomy First vs Sequential Common Bile Duct Imaging + Cholecystectomy
The purpose of this study is to evaluate if cholecystectomy first (studied group) versus sequential common bile duct imaging/cholecystectomy (control group) result in a decrease of hospital stay, morbidity/mortality and costs in…
- Trial name
- CCK first (NCT01492790)
- Testing
- Emergency cholecystectomy first, Sequential common bile duct imaging/cholecystectomy
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Gallstone, Gallstone; Cholecystitis, Acute
Indocyanine Green Fluorescence During Fundus First Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is the routine method for managing gallstone disease. This is considered a safe procedure with low risk of severe complications.
- Trial name
- INFUNDUS (NCT06918210)
- Testing
- Indocyanine Green, Cholangiography
- Volunteers
- 294 people
- Sponsor
- Karolinska Institutet
Gallstones
Feasibility of Transvaginal Cholecystectomy
Today there are three different ways to remove a gallbladder with gallstones. Surgeons can remove the gallbladder through small incisions in the abdomen. This is called laparoscopic cholecystectomy. It is the current standard.
- Trial name
- TVC (NCT01232959)
- Testing
- Transvaginal Cholecystectomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Non-Alcoholic Fatty Liver Disease, Gallstone Disease
Prevention of NAFLD and CVD Through Lifestyle Intervention
Prevention of non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease (CVD) through lifestyle intervention (MAUCO+) is a clinical trial that aims to improve sarcopenia, aerobic capacity, body composition, and lipid…
- Trial name
- MAUCO+ (NCT05618626)
- Testing
- Physical exercise and dietary intervention for NAFLD
- Where
- Chile
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Gallstone Disease
Multimedia Informed Consent & PROMs in Laparoscopic Cholecystectomy
Collection of PROMs (Patient Reported Outcome Measures) data from patients before and after an operation to remove their gallbladder for the treatment of symptomatic gallstones.
- Trial name
- EPICS (NCT02810860)
- Testing
- Laparoscopic cholecystectomy
- Where
- United Kingdom
- Volunteers
- 349 people
- Sponsor
- Nottingham University Hospitals NHS Trust