Clinical trials: Gall Stone Disease
Pancreatic Cancer, Cholangiocarcinoma
MicroRNAs as Bile-based Biomarkers in Pancreaticobiliary Cancers
pancreatic or biliary-tract cancer can be a serious diagnosis, as many patients present too late for surgery. Cancer cells have been found to release small messenger molecules called that regulate cancer genes called microRNAs…
- Conditions
- Pancreatic Cancer, Cholangiocarcinoma, Ampullary Cancer, Biliary Stricture
- Trial name
- MIRABILE (NCT06258824)
- Testing
- Small RNA Sequencing and Validation of candidate miRNAs
- Where
- United Kingdom
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Laparoscopic Cholecystectomy
Cholecystectomy Blunt Dissection
Day case laparoscopic cholecystectomy can be made with conventional diathermy hook starting at triangle of Calot´s. 5mm suction irrigation blunt dissection starting from the gallbladder fundus is another option.
- Trial name
- NCT05366920
- Testing
- dissection of gallbladder in laparoscopic cholecystectomy
- Where
- Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- Imam Mohammad ibn Saud Islamic University
Cholelithiasis
Gallstones and Concomitant Gastric Helicobacter Pylori Infection
In this study, the presence of H.Pylori in the gallbladder mucosa of patients with symptomatic gallstones undergoing cholecystectomy was investigated.
- Trial name
- NCT01810081
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Marmara University
Gallstones
EndoCone Single Port Versus Conventional Multi-port Laparoscopic Approach
Its main objective is to evaluate the clinical outcome (including patient reported outcomes) and health economic assessment (HTA) of a new re-usable system for Single Port Laparoscopic Surgery - ENDOCONE SYSTEM developed by Prof…
- Trial name
- NCT01709877
- Testing
- Cholecystectomy
- Where
- 4 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Calculus of Gallbladder With or Without Cholecystitis, Laparoscopic Cholecystectomy
Needlescopic Versus Transvaginal/Transumbilical Cholecystectomy
Laparoscopic surgery has become the golden standard for the removal of the gallbladder. Recently, developments have been made so that operations can be performed through a natural orifice instead of the abdominal wall, thus…
- Trial name
- NATCH (NCT01685775)
- Testing
- Transvaginal/transumbilical, Needlescopic with 3 trocars
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Witten/Herdecke
Gallbladder Cancer
Alcohol Consumption and Gallbladder Cancer
This case-control study matched by age and sex was performed to evaluate the region specific risk factors for gallbladder cancer in Jeju island, Korea.
- Trial name
- NCT02326948
- Where
- South Korea
- Volunteers
- 156 people
- Sponsor
- Cheju Halla General Hospital
Common Bile Duct Diseases, Common Bile Duct Calculi
Effects of Dexamethasone on Common Bile Duct Cannulation Time
The main aim of this clinical trial is to evaluate the effects of dexamethasone on common bile duct cannulation time during endoscopic retrograde cholangiopancreatography (ERCP) in patients with biliary pathologies.
- Conditions
- Common Bile Duct Diseases, Common Bile Duct Calculi, Common Bile Duct Stricture, Common Bile Duct Neoplasms
- Trial name
- NCT05945797
- Testing
- Dexamethasone 4mg
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Gujranwala medical college District Headquarters Hospital, Gujranwala
Laparoscopic Cholecystectomy, Post Operative Analgesia
Postoperative Pain After Instillation Of Bupivacaine During Laparoscopic Cholecystectomy
This study aims to compare the level of postoperative pain experienced by patients undergoing laparoscopic cholecystectomy with and without the use of intraperitoneal bupivacaine.
- Conditions
- Laparoscopic Cholecystectomy, Post Operative Analgesia, Bupivacaine
- Trial name
- BUPA-LC (NCT07098429)
- Testing
- Bupivacain (Postoperative), Normal (0.9%) saline
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh
Common Bile Duct Stones
Role of Routine on-Table Cholangiography in Laparoscopic Cholecystectomy
The purpose of this study is to assess whether routine imaging of the biliary system during routine gallbladder surgery alters clinical outcome
- Trial name
- NCT00806780
- Testing
- on table cholangiography
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Gallstones
A Clinical Trial of Electro-acupuncture for Treating Gallstone Diseases
Background: Electro-acupuncture (EA) is commonly used as an alternative treatment for gallstone disease. This study aimed to investigate the effectiveness of EA.
- Trial name
- NCT03891147
- Testing
- Electro-acupuncture
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Chinese University of Hong Kong
Gallbladder Stone
Gallbladder Stones in Children and Correlation With Etiological Factors
Aims of the Study: The objective of this study is to estimate the correlation between etiological factors and postoperative histochemical analysis of pediatric gallbladder stones.
- Trial name
- NCT06660576
- Testing
- Cholecystectomy and histochemical analysis of Gallbladder stones
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Gall Stone
Colonic Gallstone Ileus, Diagnostic-therapeutic Algorithm
Gallstone ileus is a rare complication of gallstone disease. There is no systematic review on CGI. We analyze published literature on the subject and plan to propose a diagnostic-therapeutic algorithm for CGI.
- Trial name
- NCT04961411
- Testing
- operation or non-operative treatment
- Where
- Croatia
- Volunteers
- 113 people
- Sponsor
- Tomislav Bruketa
Acute Pancreatitis Due to Gallstones
Inmediate Feeding Tolerance in Acute Pancreatitis
Objective: Determine tolerance of immediate oral intake (8 hours posterior to the beginning of treatment) against traditional management (early feeding at 48hr) in patients with mild acute pancreatitis of biliary origin.
- Trial name
- NCT03354065
- Testing
- TIME OF FEEDING
- Volunteers
- 59 people
- Sponsor
- Hospital Central "Dr. Ignacio Morones Prieto"
Choledocholithiasis
"Endoscopy First" or "Laparoscopic Cholecystectomy First" for Patients With Intermediate Risk of Choledocholithiasis
The study compares two different methods to evaluate extrahepatic bile ducts for possible stones for patients with cholecystolithiasis and intermediate risk for choledocholithiasis when laparoscopic cholecystectomy is indicated.
- Trial name
- NCT03658863
- Testing
- endoscopic ultrasound, intraoperative cholangiography, ERCP
- Where
- Lithuania
- Volunteers
- 106 people
- Sponsor
- Vilnius University
Gallstones, Gallbladder Cholesterolosis
Gallbladder Cholesterolosis, Body Mass Index and Serum Cholesterol and Triglycerides
Cholesterolosis is a common finding in biopsy specimens of gallbladders surgically removed for cholelithiasis. To the best of the investigators knowledge no study has analyzed the relationships of Body Mass Index, serum…
- Trial name
- NCT00528632
- Testing
- Specimen biopsy and serum laboratory tests
- Where
- Chile
- Volunteers
- 406 people
- Sponsor
- Cirujanos la Serena
Cholecystolithiasis, Common Bile Duct Gall Stones
ChOlanGiography Performed Routinely Versus Selectively During Cholecystectomy: A NAtional Registry-based Randomized Controlled Trial
Common bile duct stones (CBDS) may be asymptomatic but can cause pancreatitis, obstructive jaundice, and/or cholangitis. In Sweden, intraoperative cholangiography (IOC) is usually performed during gallstone surgery in order to…
- Trial name
- COGNAC (NCT07002619)
- Testing
- Routine cholangiography, Selective cholangiograpy
- Where
- Sweden
- Volunteers
- 6,000 people
- Sponsor
- Karolinska Institutet
Gallstone, Cholecystitis
A Clinical Study of Chinese Domestic Surgical Robot
This is a prospective, multi-center, randomized, single-blind, parallel-controlled clinical trial to evaluate the safety and efficacy of the Chinese domestic endoscopic instrument control system in clinical treatment.
- Trial name
- NCT04122261
- Testing
- the MicroHand S endoscopic instrument control system, the da Vinci endoscopic instrument control system
- Where
- China
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- The Third Xiangya Hospital of Central South University
Biliary Calculi
Balloon Catheter vs. Basket Catheter for Endoscopic Bile Duct Stone Extraction
Endoscopic bile duct stone (BDS) removal is a well-established treatment; however, the preference for basket or balloon catheters for extraction is operator-dependent It is reported that complete endoscopic treatment with a…
- Trial name
- NCT02909595
- Testing
- Balloon catheter, Basket catheter
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Anhui Provincial Hospital
Choledocholithiasis, Cholecystolithiasis
One-stage and Delayed Laparoscopic Cholecystectomy After Endoscopic Retrograde Cholangiopancreatography with Endoscopic Sphincterotomy in Cholecystocholedocholithiasis
In this study, it is planned to compare ERCP with ES + delayed LC in children, with one-stage LC + ERCP with ES in adults to confirm that ERCP with ES + delayed LC is more suitable for pediatric patients with…
- Conditions
- Choledocholithiasis, Cholecystolithiasis, Cholangiopancreatography, Endoscopic Retrograde, Laparoscopic Cholecystectomy
- Trial name
- NCT06676241
- Testing
- endoscopic retrograde cholangiopancreatography; laparoscopic cholecystectomy, endoscopic retrograde cholangiopancreatography;laparoscopic cholecystectomy
- Where
- Russia
- Volunteers
- 44 people
- Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)
Common Bile Duct Calculi, Acute; Cholecystitis, Choledocholithiasis
Modified Laparoscopic Transcystic Biliary Drainage in the Management of Cholecystocholedocholithiasis
The modified laparoscopic transcystic biliary drainage which we developed in the treatment of cholecystocholedocholithiasis has some advantages over conventional techniques.
- Conditions
- Common Bile Duct Calculi, Acute; Cholecystitis, Choledocholithiasis, Acute Cholecystitis With Obstruction, Acute Cholangitis
- Trial name
- NCT06011941
- Testing
- Modified laparoscopic transcystic biliary drainage
- Where
- China
- Volunteers
- 310 people
- Sponsor
- Peking University Third Hospital