Clinical trials: Gallbladder
Biliary Disease, Pancreas Disease
Laparoscopy-assisted ERCP in Patients With Altered Gastric Anatome
The purpose of this research study is to collect data on the technical aspects of Lasparoscopy-assisted ERCP and patient outcomes to help guide future medical care of patients with Roux-en-Y gastric bypass surgery.
- Trial name
- NCT01620632
- Testing
- Laparoscopy assisted ERCP
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Florida
Gall Stone
Colonic Gallstone Ileus, Diagnostic-therapeutic Algorithm
Gallstone ileus is a rare complication of gallstone disease. There is no systematic review on CGI. We analyze published literature on the subject and plan to propose a diagnostic-therapeutic algorithm for CGI.
- Trial name
- NCT04961411
- Testing
- operation or non-operative treatment
- Where
- Croatia
- Volunteers
- 113 people
- Sponsor
- Tomislav Bruketa
Acute Cholecystitis
One-year Outcomes by Index Treatment in Elderly Patients With Acute Cholecystitis
Background: The GOLDENEYE study is an international, multicenter, prospective observational investigation designed to compare the outcomes of various management strategies for acute cholecystitis in patients aged 70 years and…
- Trial name
- GOLDENEYE (NCT07006298)
- Where
- Spain
- Volunteers
- 376 people
- Sponsor
- Instituto de Investigación Sanitaria y Biomédica de Alicante
Pancreatic Cancer, Gastrointestinal Neoplasms
Permission to Collect Blood Over Time for Research
To determine whether biomarkers assessed in blood samples can be used to detect individuals at risk for developing blood clots or worsening of their underlying disease.
- Conditions
- Pancreatic Cancer, Gastrointestinal Neoplasms, Colon Rectal Cancer Adenocarcinoma, Esophageal Cancer
- Trial name
- NCT00767234
- Testing
- Observation
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Stanford University
Biliary Tract Cancer
Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer
NuTide:121 compares NUC-1031 with gemcitabine, both in combination with cisplatin, in patients with previously untreated advanced biliary tract cancer.
- Trial name
- NCT04163900
- Testing
- NUC-1031, Gemcitabine, Cisplatin
- Where
- 125 sites in United States, Australia and 13 more
- Volunteers
- 773 people
- Sponsor
- NuCana plc
Cholangiocarcinoma, Gallbladder Carcinoma
Unilateral Stenting Versus Bilateral Stenting for Malignant Hilar Biliary Obstruction
The purpose of this study is to compare the clinical effectiveness and long-term outcomes between patients with malignant hilar biliary obstruction who are treated by unilateral or bilateral stenting.
- Conditions
- Cholangiocarcinoma, Gallbladder Carcinoma, Hepatocellular Carcinoma
- Trial name
- NCT02649712
- Testing
- biliary stent
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Xuzhou Central Hospital
Biliary Tract Diseases, Gallbladder Diseases
Small-incision Open Cholecystectomy or Laparoscopic Cholecystectomy for Gallbladder Disease
The trial compares minilaparotomy (small-incision) cholecystectomy with (key-hole) laparoscopic cholecystectomy by randomly allocating patients with gallbladder disease to two groups of surgeons, each group being trained for one…
- Conditions
- Biliary Tract Diseases, Gallbladder Diseases, Cholecystitis, Cholecystolithiasis
- Trial name
- NCT00370344
- Testing
- Laparoscopic cholecystectomy, Small-incision open cholecystectomy
- Where
- 2 sites in Sweden
- Volunteers
- 355 people
- Sponsor
- Umeå University
Acinar Cell Adenocarcinoma of the Pancreas, Adenocarcinoma of the Gallbladder
Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies
This study is being done to determine the dose of a chemotherapy drug (irinotecan [irinotecan hydrochloride]) that can be tolerated as part of a combination of drugs.
- Conditions
- Acinar Cell Adenocarcinoma of the Pancreas, Adenocarcinoma of the Gallbladder, Adenocarcinoma of Unknown Primary, Adult Primary Cholangiocellular Carcinoma
- Trial name
- NCT01643499
- Testing
- oxaliplatin, irinotecan hydrochloride, leucovorin calcium
- Where
- 2 sites in United States
- Volunteers
- 79 people
- Sponsor
- University of Chicago
Biliary Tract Cancer, Cholangiocarcinoma
Identification of New Biomarkers for Patients With Cholangiocarcinoma and Gallbladder Cancer
No validated biomarkers exist that can identify patients with biliary tract cancer at an early stage or predict treatment outcomes. The objective of the present study is to find diagnostic, prognostic and predictive biomarkers.
- Conditions
- Biliary Tract Cancer, Cholangiocarcinoma, Gallbladder Cancer
- Trial name
- CHOCA (NCT05184400)
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Herlev and Gentofte Hospital
Cholecystitis
Subserosal Laparoscopic Cholecystectomy
The aim is to study the safety and efficacy of subserosal laparoscopic cholecystectomy .
- Trial name
- NCT05770128
- Testing
- laparoscope
- Volunteers
- 65 people
- Sponsor
- Assiut University
Advanced Solid Tumor, Cholangiocarcinoma
To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors
This is a Phase Ib/II, multicenter, open-label study to evaluate the safety and preliminary efficacy of TT-00420 tablet, as monotherapy or in combination regimens, in patients with advanced solid tumors (solid tumor, BTC and…
- Conditions
- Advanced Solid Tumor, Cholangiocarcinoma, Biliary Tract Cancer, HER2-negative Breast Cancer
- Trial name
- NCT05253053
- Testing
- TT-00420, Combination Product: Atezolizumab, Combination Product: Nab-Paclitaxel
- Where
- 9 sites in China
- Volunteers
- 84 people
- Sponsor
- TransThera Sciences (Nanjing), Inc.
Surgery, Pain, Postoperative
Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial
This trial is being completed to compare two commonly used options to treat pain after surgery. Participants that undergo gallbladder removal, hernia repair, and breast lump removal will be eligible to enroll.
- Trial name
- CARES (NCT05722002)
- Testing
- NSAID, Opioid, Acetaminophen
- Where
- 8 sites in United States, Canada
- Volunteers
- 900 people
- Sponsor
- University of Michigan
Gallbladder Carcinoma
Comprehensive Genomic Profiling Combined With Real Life Data of "The German-Registry of Incidental Gallbladder Carcinoma"
Multicenter German- Registry of Incidental Gallbladder Carcinoma combining clinical real-world data and comprehensive genomic profiling.
- Trial name
- NCT05222854
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Solid Tumors
Effect of Different Doses of AMG 706 on the Gallbladder in Advanced Solid Tumors
The study involves the use of three different dosing regimens of AMG 706 in patients with advanced solid tumors to see how the drug affects the gallbladder size and function.
- Trial name
- NCT00448786
- Testing
- AMG 706
- Volunteers
- 49 people
- Sponsor
- Amgen
Anal Cancer, Carcinoma of the Appendix
Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer
RATIONALE: Palonosetron hydrochloride may prevent nausea and vomiting caused by radiation therapy. It is not yet known whether palonosetron hydrochloride is more effective than a placebo in preventing nausea and vomiting.
- Conditions
- Anal Cancer, Carcinoma of the Appendix, Colorectal Cancer, Extrahepatic Bile Duct Cancer
- Trial name
- NCT00903396
- Testing
- palonosetron hydrochloride
- Where
- 69 sites in United States
- Volunteers
- 7 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Cholecystitis, Chronic Calculous Cholecystitis
Indocyanine Green Fluorescent Cholangiography and Intraoperative Angiography With Laparoscopic Cholecystectomy
This was a double blinded, randomized, controlled trial involved patients underwent laparoscopic cholecystectomy
- Conditions
- Cholecystitis, Chronic Calculous Cholecystitis, Acute Calculous Cholecystitis
- Trial name
- NCT05125653
- Testing
- Indocyanine Green Fluorescent Laparoscopic Cholangiography, White Light
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Ain Shams University
Gallstone
Frequency of Patho-morphological Classes of Gall Stones in Lahore, Pakistan
It is a cross sectional study in which we are tying to determine frequency of type of gall stones in our setup(Lahore, Pakistan).
- Trial name
- NCT03594409
- Testing
- Biochemistry of gall stones
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Services Hospital, Lahore
Biliary Disease
Evaluating the Safety and Efficacy of Duloxetine in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis
Endoscopic retrograde cholangiopancreatography (ERCP (, a key tool that is used in diagnosis and treatment of pancreato-biliary diseases.
- Trial name
- NCT06860984
- Testing
- Duloxetine
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Cholecystitis, Postoperative Pain
Postoperative Pain Results According to Pressure to Form Pneumoperitoneum
This study showed the difference in postoperative pain between the groups that performed surgery with the low-pressure pneumoperitoneum and the group that performed surgery in the standard-pressure pneumoperitoneum when robotic…
- Trial name
- NCT04398810
- Testing
- robotic single port cholecystectomy
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul St. Mary's Hospital
Common Bile Duct Gallstones
Conventional Versus Rendezvous Technique of Intraoperative Endoscopic Retrograde Cholangiopancreatography
One of the new methods for management of common bile duct stones is intraoperative endoscopic sphincterotomy. It can be performed by many techniques.
- Trial name
- NCT01190332
- Testing
- endoscopic sphincterotomy by conventional method, endoscopic sphincterotomy by rendezvous method
- Where
- Egypt
- Volunteers
- 98 people
- Sponsor
- Mansoura University