Clinical trials: Gallbladder
Cholecystolithiasis and Thyroid Nodule
Effect of Different Infusion Volume on Perioperative Bladder and Blood Volume in Patients Undergoing Daytime Surgery.
The objective of the trial was to explore the effect of different infusion volume on perioperative bladder and blood volume in patients undergoing daytime surgery assisted by bladder and vascular ultrasound and transthoracic…
- Trial name
- NCT03924804
- Testing
- Ringer's solution acetate
- Where
- China
- Volunteers
- 90 people
- Sponsor
- China Medical University, China
Hepatocellular Cancer, Cholangiocarcinoma
The PLATON Network
The PLATON Network study is designed to elevate personalized therapy based on genomic tumor profiles in gastrointestinal cancer patients. Hereby, PLATON's study-design focuses on the patient's tumor molecular profiling.
- Conditions
- Hepatocellular Cancer, Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer
- Trial name
- PLATON (NCT05489250)
- Where
- 31 sites in Germany
- Volunteers
- 565 people
- Sponsor
- Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Pancreas Cancer, Pancreatic Cancer
Quebec Pancreas Cancer Study
The Quebec Pancreas Cancer Study is a prospective clinic-based study consisting of clinical, family history and epidemiologic data, with accompanying biospecimens, from patients diagnosed with either pancreas cancer, a related…
- Conditions
- Pancreas Cancer, Pancreatic Cancer, Pancreas Neoplasm, Pancreas Cyst
- Trial name
- QPCS (NCT04104230)
- Where
- Canada
- Volunteers
- 2,000 people
- Sponsor
- George Zogopoulos
Cholecystitis, Chronic
Comparison Between Oral Gabapentin Versus Diclofenac Sodium in Post-operative Analgesia Laparoscopic Cholecystectomy
this study amis to compare between perioperative oral Gabapentin versus Diclofenac sodium on postoperative analgesia patients undergoing laparoscopic cholecystectomy
- Trial name
- NCT07131527
- Testing
- Gabapentin, Diclofenac Sodium
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Gallbladder Cancer, Cholangiocarcinoma
Gem+Nab-P+LEN+TIS for Advanced Unresectable BTC (GALENT-BT)
The goal of this clinical trial is to evaluate the efficacy and safety of combining Gemcitabine, nab-Paclitaxel, Lenvatinib, and Tislelizumab in adults aged 18-75 years with advanced unresectable biliary tract malignancies…
- Trial name
- GALENT-BT (NCT06963060)
- Testing
- Gemcitabine nab-PaclitaxelLenvatinibTislelizumab
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Wei Gong
Surgery, Biliary Disease
Bile Duct Injury Digestif
Data accumulated from medical record collected from January 2008 until December 2018
- Conditions
- Surgery, Biliary Disease, Bile Duct Injury, Sepsis
- Trial name
- NCT04582240
- Testing
- no intervention
- Volunteers
- 24 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Calculus Biliary
Management for Concomitant Gallstones and Common Bile Duct Stones.
Choledocholithiasis is identified in approximately 3-10 % of patients with cholelithiasis. (1-3) While laparoscopic cholecystectomy (LC) is considered the treatment of choice in patients with gall bladder stones, there is a…
- Trial name
- NCT04758923
- Testing
- Cholecystectomy
- Volunteers
- 64 people
- Sponsor
- Assiut University
Acute Cholecystitis
The Comparison of Hemodynamic Effects Between Remimazolam-remifentanil and Propofol-remifentanil in Patients Undergoing Laparoscopic Cholecystectomy
This study is conducted to determine whether the occurrence of hypotension is reduced by the combined use of remimazolam and remifentanil compared to the conventional combination use of propofol and remifentanil.
- Trial name
- NCT05164159
- Testing
- propofol group, remimazolam group
- Where
- South Korea
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Cholecystitis, Acute
Ultrasonically Activated Scalpel Versus Electrocautery Based Dissection in Acute Cholecystitis Trial
The present study aims at analyzing whether ultrasonic tissue coagulation dissection technique offers a smoother peri- and postoperative course and reduces the risk for conversion from laparoscopic to open surgery in acute…
- Trial name
- NCT03014817
- Testing
- Ultrasonically activated scalpel, Electrocautery
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- Karolinska Institutet
Pain, Acute
Gall Bladder Bed Infiltration Analgesia
Early postoperative pain is a common complaint after elective laparoscopic cholecystectomy. Persistent acute postoperative pain is the dominating complaint and the primary reason for a prolonged stay after this procedure.
- Trial name
- NCT03693820
- Testing
- the infiltration group, the control group
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Alaa Mazy Mazy
Cholecystolithiasis
Day Case Laparoscopic Cholecystectomy: Fundus First With Ultrasonic Dissection or Conventional Diathermy Hook
Day case laparoscopic cholecystectomy can be made with conventional diathermy hook starting at triangle of Calot´s. Ultrasonic dissection starting from the gallbladder fundus is another option.
- Trial name
- NCT01553331
- Testing
- dissection of gallbladder in laparoscopic cholecystectomy
- Where
- Finland
- Volunteers
- 169 people
- Sponsor
- Central Finland Hospital District
Gall Stones (& [Calculus - Gall Bladder]), Anesthesia
Segmental Spinal Anesthesia for Small-incision Cholecystectomy in a Field Hospital
Providing safe and efficient anesthesia and in a field hospital is a challenging situation. This study investigated the feasibility and safety of thoracic spinal anesthesia for small-incision open cholecystectomy in a deployed…
- Trial name
- SPICHOL (NCT05165641)
- Testing
- segmental spinal anesthesia
- Volunteers
- 62 people
- Sponsor
- Avicenna Military Hospital
Biliary Drainage, Endoscopic Ultrasound-Guided Drainage
Real-world Evaluation of Different Endoscopic Biliary Drainage Techniques in Patients With Jaundice of Biliopancreatic Malignant Origin
The incidence of pancreatic cancer is rising. Tumor-induced obstruction of the distal bile duct is a common complication, occurring during the course of nearly 80% of pancreatic tumors.
- Conditions
- Biliary Drainage, Endoscopic Ultrasound-Guided Drainage, Pancreatic Cancer
- Trial name
- PROBILEUS (NCT07817602)
- Testing
- Endoscopic drainage
- Where
- 6 sites in France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Frailty, Gallbladder Diseases
Frailty is a Risk Factor Postcholecystectomy
The goal of this observational study is to learn about the long-term effects of cholecystectomy in patients over the age of 60 who take cholecystectomy to treat their acute cholecystitis).
- Trial name
- NCT07696078
- Testing
- cholecystectomy open
- Sponsor
- Zagazig University
Biliary Tract Cancer
Testing Ivonescimab Versus FOLFOX in Advanced Biliary Tract Cancer Patients
The object of this trial is to test whether ivonescimab is superior to standard chemotherapy (FOLFOX regimen) for the treatment of patients with advanced biliary tract cancer after failure of a first line of chemotherapy.
- Trial name
- SEVILLA (NCT06529718)
- Testing
- Ivonescimab, FOLFOX regimen
- Where
- 42 sites in France, United Kingdom
- Volunteers
- 72 people
- Sponsor
- UNICANCER
Colon Adenocarcinoma, Rectal Adenocarcinoma
Evaluating Novel Therapies in ctDNA Positive GI Cancers
This study is a non-randomized, open-label, multi-cohort, multi-site, pilot feasibility therapeutic trial. The study will enroll 20 patients across 4 cohorts (CRC, gastric, PDAC, and HCC/intra-hepatic-/extra-hepatic-, gall…
- Conditions
- Colon Adenocarcinoma, Rectal Adenocarcinoma, Gastric Adenocarcinoma, Pancreatic Adenocarcinoma
- Trial name
- MRD-GI (NCT05482516)
- Testing
- Atezolizumab, Bevacizumab
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Georgetown University
Acute Cholecystitis
Evaluation of a Protocol for Multidisciplinary Management of Acute Cholecystitis.
Acute cholecystitis is a complex disease and its management is sometimes controversial. Two main factors contribute to its complexity: the patient's surgical risk and the possibility of concomitant choledocholithiasis.
- Trial name
- NCT04543578
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Fundacion Miguel Servet
Peripheral T Cell Lymphoma, Diffuse Large B Cell Lymphoma
A Study of STI-3031 (an Anti-PD-L1 Antibody) in Patients With Selected Relapsed/Refractory Malignancies
This study evaluates the efficacy, as measured by the objective response rate, of STI-3031, an anti-PD-L1 antibody, in previously treated patients with selected advanced lymphomas or biliary tract cancer.
- Conditions
- Peripheral T Cell Lymphoma, Diffuse Large B Cell Lymphoma, Biliary Tract Cancer, Extranodal NK T Cell Lymphoma, Nasal
- Trial name
- NCT03999658
- Testing
- STI-3031
- Sponsor
- Sorrento Therapeutics, Inc.
Gallbladder Diseases
A Novel Technique For Gall Bladder Fundus Retraction In Single Incision Laparoscopic Cholecystectomy
The investigators describe a novel technique for GB fundus retraction.
- Trial name
- NCT01413633
- Testing
- cholecystectomy
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cholelithiasis, Difficult Gallbladder Extraction
Tri-Radial Port Extension for Difficult Gallbladder Extraction
Laparoscopic cholecystectomy is a common operation for gallbladder stones. In some patients, the removed gallbladder is difficult to extract through the umbilical port because it is large, thick-walled, or packed with stones.
- Conditions
- Cholelithiasis, Difficult Gallbladder Extraction, Laparoscopic Cholecystectomy Surgery, Port-Site Fascial Extension
- Trial name
- TPE-LC (NCT07595692)
- Testing
- Vertical Fascial Extension, Horizontal Fascial Extension, Tri-Radial Fascial Micro-Incision
- Where
- Bangladesh
- Volunteers
- 156 people
- Sponsor
- Bangladesh Navy