Clinical trials: Gallbladder Stone
Choledocholithiasis
Left Lateral Position and Prone Position for Endoscopic Retrograde Cholangiopancreatography
Endoscopic retrograde cholangiopancreatography (ERCP) has been widely used in diagnosis and treatment of pancreaticobiliary diseases. Traditionally, ERCP has been performed in the prone position.
- Trial name
- NCT02594475
- Testing
- Endoscopic retrograde cholangiopancreatography
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Ovarian Cancer, Cholecystolithiasis
Safety of Opportunistic Salpingectomy During Elective Laparoscopic Cholecystectomy.
The knowledge, coupled with epidemiological studies demonstrating lower ovarian cancer rates in women with a history of tubal sterilization has led to recommendations for opportunistic salpingectomy at the time of benign…
- Trial name
- NCT07642791
- Testing
- Opportunistic salpingectomy, Cholecystectomy
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- University of Zurich
Choledocholithiasis, Gallstone Migration
Prospective Validation of "Cholecystectomy First" Strategy for Gallstone Migration
Initial cholecystectomy with intraoperative cholangiogram, followed if required by ERCP, has been implemented at the investigators institution as the standard management strategy for patients at intermediate risk of common bile…
- Conditions
- Choledocholithiasis, Gallstone Migration, Cholecystitis, Gallstone Pancreatitis
- Trial name
- NCT02461147
- Testing
- Cholecystectomy with intraoperative cholangiogram
- Where
- Switzerland
- Volunteers
- 161 people
- Sponsor
- University Hospital, Geneva
Biliary Disease, Common Bile Duct Calculi
Needle Knife Fistulotomy Versus Partial Ampullary Endoscopic Mucosal Resection for Difficult Biliary Cannulation
The aims of this study are to compare the needle knife fistulotomy (NKF) technique versus the partial ampullary endoscopic mucosal resection (PA-EMR) technique in patients with difficult biliary cannulation and to assess the…
- Conditions
- Biliary Disease, Common Bile Duct Calculi, Biliary Stricture, Malignant Hepatobiliary Neoplasm
- Trial name
- NCT05068739
- Testing
- PA-EMR, NKF
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Duzce University
Acute Pancreatitis, Pancreatitis Due to Gallstones
Machine learnINg for the rElapse Risk eValuation in Acute Biliary Pancreatitis.
The MINERVA (Machine learnINg for the rElapse Risk eValuation in Acute biliary pancreatitis) project stems from the need in the clinical practice of taking an operational decision in patients that are admitted to the hospital…
- Conditions
- Acute Pancreatitis, Pancreatitis Due to Gallstones, Pancreatitis Biliary, Pancreatitis Relapsing
- Trial name
- MINERVA (NCT06124989)
- Testing
- MINERVA Machine Learning model
- Where
- Italy
- Volunteers
- 430 people
- Sponsor
- University of Cagliari
Choledocholithiasis With Acute Cholangitis (Diagnosis), Acute Pancreatitis Due to Gallstones
Complications After Endoscopic Retrograde Cholangiopancreatography
Retrospective study to analyze benign complications and malignancy risks after ERCP with sphincterotomy. All patients who received a ERCP with sphincterotomy for a benign disease will be included.
- Trial name
- ERCP (NCT04735224)
- Volunteers
- 500 people
- Sponsor
- Juan Carlos Martín del Olmo
Acute Pancreatitis Due to Gallstones, Acute Pancreatitis
PrEveNtion of Biliary Events After Acute Pancreatitis in NonSUrgicaL PAtients: PENINSULA Trial
Acute pancreatitis (AP) is a common condition and its main etiology is biliary. Cholecystectomy is the standard preventive treatment for recurrence of AP after admission.
- Trial name
- PENINSULA (NCT06409741)
- Testing
- Biliary sphincterotomy
- Where
- 5 sites in Spain
- Volunteers
- 126 people
- Sponsor
- Hospital General Universitario de Alicante
Cholecystectomy, Robotic, Cholecystectomy, Laparoscopic
Surgical Techniques: Robotic Versus Conventional Laparoscopic Cholecystectomy IN Benign Gallbladder Disease
This is a single-center, randomized controlled, parallel, non-inferiority trial. All adult patients with benign gallbladder disease with an indication for cholecystectomy will be assessed for eligibility and included after…
- Conditions
- Cholecystectomy, Robotic, Cholecystectomy, Laparoscopic, Cholecystectomy, Gallstones
- Trial name
- STaRLING (NCT07119203)
- Testing
- Robotic cholecystectomy, Laparoscopic cholecystectomy
- Where
- United Kingdom
- Volunteers
- 276 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Choledocholithiasis
Papillary Balloon Dilation Versus Intraductal Lithotripsy
Our aim is to compare the efficacy, safety, procedural time required, and costs of a strategy initially employing cholangioscopy guided intraductal lithotripsy (laser/electrohydraulic lithtripsy (EHL)) versus a strategy initially…
- Trial name
- NCT03536247
- Testing
- Initial therapy with papillary balloon dilation, Initial therapy with intraductal lithotripsy
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Gallstones
Feasibility of Transvaginal Cholecystectomy
Today there are three different ways to remove a gallbladder with gallstones. Surgeons can remove the gallbladder through small incisions in the abdomen. This is called laparoscopic cholecystectomy. It is the current standard.
- Trial name
- TVC (NCT01232959)
- Testing
- Transvaginal Cholecystectomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Choledocholithiasis
Prospective Comparison of the Carbon Footprint of EUS vs MRCP for Evaluation of Suspected Choledocholithiasis
MRCP and EUS are diagnostically equivalent in detecting CBD stones among patients with intermediate risk, as shown in a landmark RCT.
- Trial name
- NCT07283185
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Asian Institute of Gastroenterology, India
Acute Cholecystitis
Early Versus Delayed Laparoscopic Cholecystectomy for Acute Cholecystitis
The goal of this clinical trial is to learn if performing gallbladder surgery early is as safe and effective as delaying it for people with acute cholecystitis (a sudden gallbladder infection).
- Trial name
- EDLC-AC (NCT07101315)
- Testing
- Laparoscopic Cholecystectomy
- Where
- 2 sites in Yemen
- Volunteers
- 81 people
- Sponsor
- Sana'a University
Uterine Fibroids (Leiomyoma), Ovarian Tumors
TEAS Combined With Triple Antiemetic Drugs to Prevent PONV in High-Risk Patients
The goal of this clinical trial is to evaluate the effects of transcutaneous electrical acupoint stimulation (TEAS) combined with triple antiemetics for postoperative nausea and vomiting (PONV) in high-risk patients.
- Conditions
- Uterine Fibroids (Leiomyoma), Ovarian Tumors, Gallstones
- Trial name
- NCT07480785
- Testing
- transcutaneous electrical acupoint stimulation, triple antiemetic drugs
- Where
- China
- Volunteers
- 780 people
- Sponsor
- Zhejiang University
Fluorenscent Image Guided Surgery, Indocyanide Green
Intra-gallbladder or Systemic Indocyanide Green Injection Facilitate Cholecystectomy.
The investigators will collect the pre-operative medical history and arrange physical examination, life quality evaluation, blood and biochemical test.
- Trial name
- NCT03024892
- Testing
- ICG GB, ICG IV, LC conventional
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- Chang Gung Memorial Hospital
Cholecystolithiasis
Warmed, Humidified Carbon Dioxide Insufflation vs Standard Carbon Dioxide in Laparoscopic Cholecystectomy
The purpose of this study is to determine the effect of warmed, humidified carbon dioxide Insufflation vs standard carbon dioxide in laparoscopic cholecystectomy.
- Trial name
- NCT01667848
- Testing
- Optitherm® device activated, Optitherm® device inactivated
- Where
- Austria
- Volunteers
- 148 people
- Sponsor
- Kepler University Hospital
Uncomplicated Cholelithiasis, Cholecystectomy
Oxidative Stress in Standard Laparoscopic vs Single Port Cholecystectomy
Study of Oxidative Stress Markers in order to assess whether there are differences between standard laparoscopic cholecystectomy vs single port cholecystectomy for uncomplicated cholelithiasis
- Conditions
- Uncomplicated Cholelithiasis, Cholecystectomy, Laparoscopy, Standard Technique
- Trial name
- NCT01211743
- Testing
- Laparoscopic cholecystectomy, Single incision laparoscopic cholecystectomy
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- G. Hatzikosta General Hospital
Pathology
Incidental Cancer in Gallbladder Surgical Specimens Focus on Elderly Patients
Causes such as long-term stones and polyp are thought to play a role in the etiology of gallbladder cancer. The routine histopathological examination provides the detection of incidental gallbladder cancers.
- Trial name
- NCT04352478
- Testing
- Histopathological result
- Where
- Turkey (Türkiye)
- Volunteers
- 2,389 people
- Sponsor
- Dr. Ersin Arslan Education and Training Hospital
Sustainability, Gallstone
Informing Patients About Their Surgery's Environmental Impact: an Effective Pathway to Sustainable Healthcare?
The healthcare sector contributes significantly to climate change. Reducing the number of patients receiving resource-intensive procedures such as surgery can lower carbon emissions, particularly when two treatments with…
- Conditions
- Sustainability, Gallstone, Decision Aid, Decision Making ,Shared
- Trial name
- NCT07505238
- Testing
- Sustainability added to decision aid
- Where
- Netherlands
- Volunteers
- 400 people
- Sponsor
- University of Amsterdam
Cholecystitis/Cholelithiasis, Cholecystitis; Gallstone
Potential Pulmonary Benefit of Low Pressure Laparoscopic Cholecystectomy in Selected Patients
Standard Pressure Laparoscopic Cholecystectomy，as the standard for cholecystectomy, can lead to about 15% of pulmonary atelectasis.
- Conditions
- Cholecystitis/Cholelithiasis, Cholecystitis; Gallstone, Polyp Gallbladder
- Trial name
- POPLOP (NCT04670952)
- Testing
- Low Pressure Laparoscopic Cholecystectomy, Standard Pressure Laparoscopic Cholecystectomy
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Peking Union Medical College Hospital
Cholecystectomy, Gallbladder
EUS-Guided Gallbladder Drainage Versus Conservative Management in Patients Unfit for Surgery After a Biliary Event Without Cholecystitis. DRECON Study
Cholecystectomy is considered the standard definitive treatment after an acute biliary event (biliary colic, acute pancreatitis, cholangitis, or choledocholithiasis).
- Conditions
- Cholecystectomy, Gallbladder, Endoscopic Ultrasound (EUS), Cholelithiasis
- Trial name
- DRECON (NCT07655778)
- Testing
- EUS-guided gallbladder drainage (EUS-GBD), Conservative management (CM)
- Volunteers
- 110 people
- Sponsor
- Hospital Mutua de Terrassa