Clinical trials: Gallstone
Cholelithiases, Cholecystolithiasis
Comparison of Anaesthesia Requirement for Ventilation With Endotracheal Tube Versus Proseal Laryngeal Mask Airway
Endotracheal tube (ETT) is the gold standard conduit for providing controlled ventilation during general anaesthesia (GA). however, the supra-glottic airway (SGA) devices in particular the laryngeal mask airway (LMA) and its…
- Trial name
- NCT03812718
- Testing
- Endotracheal tube (ETT), ProSeal Laryngeal Mask Airway (PLMA)
- Where
- India
- Volunteers
- 160 people
- Sponsor
- Sir Ganga Ram Hospital
Obesity, Gallstones
Obeticholic Acid in Bariatric and Gallstone Disease
By binding to the nuclear receptor FXR, bile acids not only regulate their own turn-over but presumably also pivotal steps in cholesterol, triglyceride and glucose metabolism as shown in laboratory animals.
- Trial name
- OCABSGS (NCT01625026)
- Testing
- Obeticholic acid
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Sahlgrenska University Hospital
Postoperative Pain, Cholelithiasis
Effect of Labetalol, Magnesium Sulfate, or Lidocaine on Opioid Consumption During Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy (gallbladder removal) is one of the most common abdominal operations performed worldwide. Despite its minimally invasive approach, up to half of patients experience notable postoperative pain, which…
- Trial name
- NCT07865455
- Testing
- Labetalol, Magnesium Sulfate, Lidocaine
- Volunteers
- 90 people
- Sponsor
- Assiut University
Bariatric Surgery Candidate
Sleeve Gastrectomy and Cholecystectomy Are Safe in Obese Patients With Asymptomatic Cholelithiasis
Introduction: Obesity is an increasingly serious public health problem on a global level. Gallstones may become symptomatic after sleeve gastrectomy surgery.
- Trial name
- NCT04878640
- Testing
- patients with morbid obesity and gall bladder stone underwent concomitant laparoscopic cholecystectomy in the same setting during laparoscopic sleeve gastrectomy, patients with morbid obesity and gall bladder stone underwent laparoscopic sleeve gastrectomy without concomitant laparoscopic cholecystectomy
- Volunteers
- 222 people
- Sponsor
- Zagazig University
Cholelithiasis, Cholecystitis
Investigation of the Effects of Aromatherapy Foot Massage on Postoperative Pain, Sleep, and Recovery in Laparoscopic Cholecystectomy
This randomized controlled study aims to evaluate the effects of aromatherapy foot massage on postoperative pain, sleep quality, and recovery in patients undergoing laparoscopic cholecystectomy.
- Conditions
- Cholelithiasis, Cholecystitis, Gallbladder Diseases, Postoperative Pain
- Trial name
- NCT07363668
- Testing
- aromatherapy foot massage
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Ataturk University
Mirizzi Syndrome, Cholelithiasis
Treatment of Mirizzi Syndrome
Mirizzi syndrome is an infrequent complication of long-standing cholelithiasis. Extrinsic compression of the common hepatic duct is usually caused by an impacted stone in Hartmann's pouch or cystic duct resulting in the…
- Conditions
- Mirizzi Syndrome, Cholelithiasis, Acute Cholecystitis
- Trial name
- NCT04672902
- Testing
- Single-operator cholangioscopy guided electrohydraulic lithotripsy
- Where
- Mexico
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Tecnologico de Monterrey
Cholecystitis, Cholelithiasis
Use of Robotics for Cholecystectomy; Retrospective Review of Outcomes, Set Up and Learning Curves
Comparing the use of surgical robotics during a Cholecystectomy, comparing different platforms and approaches (multi port verses single port).
- Trial name
- NCT03059745
- Testing
- Cholecystectomy
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of California, Davis
Gallstones
EndoCone Single Port Versus Conventional Multi-port Laparoscopic Approach
Its main objective is to evaluate the clinical outcome (including patient reported outcomes) and health economic assessment (HTA) of a new re-usable system for Single Port Laparoscopic Surgery - ENDOCONE SYSTEM developed by Prof…
- Trial name
- NCT01709877
- Testing
- Cholecystectomy
- Where
- 4 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Choledocholithiasis, Bile Duct Diseases
Cholangiography Using Carbon Dioxide Versus Iodinated Contrast in ERCP
Carbon dioxide (CO2) gas is widely used for luminal insufflation during endoscopic retrograde cholangiopancreatography (ERCP) of the biliary tract.
- Conditions
- Choledocholithiasis, Bile Duct Diseases, Bile Duct Carcinoma
- Trial name
- NCT02611453
- Testing
- "Air" contrast cholangiography using carbon dioxide gas
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Virginia
Gallbladder Malignant Neoplasm
Validation of the Association Between the Abundance of Three Bacterial Genera in Stool Samples and the Risk of Gallbladder Cancer in South American Patients With Gallstones
In our previous work, we found three types of bacteria in stool samples from South American patients with gallstones linked to a higher risk of gallbladder cancer.
- Trial name
- NCT07635745
- Where
- 4 sites in Bolivia, Chile and 2 more
- Volunteers
- 120 people
- Sponsor
- Centre Paul Strauss
Choledocholithiasis
Comparison of Papillary Balloon Dilatation Vs.Sphincterotomy for Lithotripsy in Difficult Sphincterotomy or Distal CBD Tapering
Compare endoscopic papillary balloon dilatation vs. endoscopic sphincterotomy for bile duct stones in: when sphincterotomy is difficult (periampullary diverticulum, prior sphincterotomy or Billroth II anastomosis) when there is…
- Trial name
- NCT00329888
- Testing
- Endoscopic papillary balloon dilatation, Endoscopic sphincterotomy
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Gallstone
The Discovery of the Double Sphincter in Gallbladder
We found a new Double sphincter which located in the neck of gallbladder，we supposed it may be related to control pressure of bile duct.Its formation is related to genetic factors.
- Trial name
- NCT01998451
- Testing
- Tauroursodeoxycholic acid
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Cholelithiasis, Metabolic Syndrome
Effect of Laparoscopic Cholecystectomy on Risk of Metabolic Syndrome
Prospective cohort study. POPULATION: patients with gallstone disease qualified for laparoscopic cholecystectomy INTERVENTION: patients undergoing cholecystectomy for gallstones COMPARISON: gallstone disease without surgery in an…
- Trial name
- NCT05557669
- Testing
- Laparoscopic cholecystectomy
- Where
- Poland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Brothers Hospitallers Hospital in Cracow
CHRONIC LIVER DISEASE
ASSESSMENT OF SURGICAL RISK IN PATIENTS WITH CHRONIC LIVER DISEASE USING VOCAL PENN SCORE
4a. Primary To assess postoperative mortality at 30 and 90 days using the VOCAL PENN score 4b. Secondary To assess potential differences in prediction accuracy between VOCAL-Penn and MELD for 30 and 90-day mortality
- Trial name
- vocal penn 01 (NCT06227988)
- Testing
- patients with liver disease who undergoing surgery, patients with liver disease who do not undergoing surgery
- Where
- India
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Gallstone, Bile Duct Obstruction
Treatment Outcomes in Bile Duct Stones
This registry is to evaluate the procedural and clinical outcomes in patients undergoing endoscopic treatment of bile duct stones when utilizing an algorithmic management approach.
- Conditions
- Gallstone, Bile Duct Obstruction, Bile Duct Diseases
- Trial name
- NCT04145843
- Testing
- endoscopic retrograde cholangiopancreatography
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- AdventHealth
Atelectasis, Postoperative, Cholecystitis; Gallstone
Ultrasound for Postop Lung Issues in Low-Flow Anesthesia
Detecting possible atelectasis and other respiratory problems that may develop immediately after extubation via lung ultrasonography can reduce pulmonary complications by performing necessary interventions such as oxygen support…
- Conditions
- Atelectasis, Postoperative, Cholecystitis; Gallstone, Pulmonary Atelectasis
- Trial name
- NCT06824506
- Testing
- No-intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Cholelithiasis, Cholecystitis
Efficacy of Proficiency-based Versus Free Laparoscopic Training in Cholecystectomy on a Virtual Reality Simulator
Virtual reality devices are widely accepted tools to familiarize surgical novices with the principles of laparoscopy. Free Virtual reality training will be tested against basic training and efficacy assessed in a randomized…
- Conditions
- Cholelithiasis, Cholecystitis, Cholecystolithiasis
- Trial name
- NCT01615549
- Testing
- Laparsocopic cholecystectomy
- Where
- 2 sites in Switzerland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Gall Stone Disease, Polyp
Combined Spinal Epidural Anesthesia and General Anesthesia for Laparoscopic Cholecystectomy
The aim of this study was to compare general anesthesia (GA) and combined (epidural and spinal) anesthesia (CA) for laparoscopic cholecystectomy. General anesthesia is a gold standard for laparoscopic cholecystectomy(LC).
- Trial name
- NCT02317510
- Testing
- combined anesthesia, general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
COLIC, BILIARY TRACT DISEASES
Treatment of Suspected Cholelithiasis With Nitroglycerin
ABSTRACT: Sublingual nitroglycerin has been advocated for the treatment of acute pain from suspected symptomatic cholelithiasis. There is, however, no clinical studies that validate its use.
- Trial name
- NCT01715220
- Testing
- sublingual nitroglycerine
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- United States Naval Medical Center, San Diego
Cholelithiasis, Ultrasonography
Laparoscopic Versus Transabdominal Ultrasound in Morbidly Obese Patients
The objective of this study is to prospectively compare laparoscopic ultrasound to transabdominal ultrasound for the detection of gallbladder pathology in obese patients presenting for laparoscopic gastric bypass.
- Conditions
- Cholelithiasis, Ultrasonography, Laparoscopic Gastric Bypass
- Trial name
- NCT00971750
- Where
- United States
- Volunteers
- 253 people
- Sponsor
- Gundersen Lutheran Medical Foundation