Clinical trials: Gastrectomy, open to volunteers
Bariatric Surgery (Sleeve Gastrectomy )
The Effect of Tele-Counseling Service on Nutrition, Exercise Attitude, and Medication Adherence After Bariatric Surgery
The aim of this study was to evaluate the effects of teleconsultation service on nutrition, exercise attitudes and medication adherence after bariatric surgery.
- Trial name
- NCT07137117
- Testing
- Behavioral Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cukurova University
Postoperative Muscle Loss
Postoperative Muscle Loss After Gastrectomy
Investigating postoperative muscle loss after gastrectomy
- Trial name
- NCT07331038
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Bariatric Surgery, Roux-en Y Gastric Bypass
Gastro-Intestinal Digestion and Physiology After Bariatric Surgery
The goal of this clinical trial is to characterize gastrointestinal digestion and physiology in patients after bariatric surgery, or people living with obesity.
- Conditions
- Bariatric Surgery, Roux-en Y Gastric Bypass, Sleeve Gastrectomy, Obesity & Overweight
- Trial name
- GIBa (NCT07286968)
- Testing
- Gastro-intestinal aspiration, Telemetric
- Where
- Netherlands
- Volunteers
- 51 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Liver Cirrhoses, Portal Hypertension Related to Cirrhosis
Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease
Cirrhosis is a form of advanced liver disease that can lead to serious complications, especially when combined with severe obesity.
- Conditions
- Liver Cirrhoses, Portal Hypertension Related to Cirrhosis, Severe Obesity, TIPS
- Trial name
- OPTIMAL (NCT07058155)
- Testing
- Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Cleveland Clinic
Postoperative Pain
External Oblique Intercostal Block Versus Erector Spinae Plane Block on Postoperative Pain in Laparoscopic Radical Gastrectomy
Postoperative pain is highly prevalent following laparoscopic radical gastrectomy. Although the erector spinae plane block (ESPB) can effectively alleviate this pain, it still has many limitations.
- Trial name
- NCT07396545
- Testing
- External Oblique Intercostal Plane Block, Erector Spinae Plane Block (ESPB) group
- Where
- China
- Volunteers
- 184 people
- Sponsor
- General Hospital of Ningxia Medical University
Obesity, Morbid, Postmenopause
Serum Estradiol and Endometrial Thickness After Bariatric Surgery in Postmenopausal Women With Obesity
Obesity changes how the body produces and processes estrogen. After menopause, higher estrogen exposure is linked to thickening of the lining of the womb (endometrium) and a higher risk of endometrial cancer.
- Conditions
- Obesity, Morbid, Postmenopause, Endometrial Thickening
- Trial name
- NCT07919054
- Testing
- Bariatric surgery, Conventional non-surgical obesity management
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Kasr El Aini Hospital
Obesity, Type 2 Diabetes
Sleeve Gastrectomy and Roux-en-Y Gastric Bypass in the Treatment of Type 2 Diabetes Mellitus.
Obesity is a growing epidemic throughout the world and is followed by increasing incidence of type 2 diabetes that accounts for 90-95% of all cases of diabetes.
- Conditions
- Obesity, Type 2 Diabetes, Bariatric Surgery
- Trial name
- CONTROL (NCT01984762)
- Testing
- Roux-en-Y gastric bypass, sleeve gastrectomy
- Where
- Sweden
- Volunteers
- 134 people
- Sponsor
- Göteborg University
Morbid Obesity
Bougie Sleeve Trial
Staple-line leak is the most frequent and incapacitating complication after laparoscopic sleeve gastrectomy (LSG). The aim of this prospective randomized trial is to compare the staple-line leak rate after LSG according to the…
- Trial name
- BOUST (NCT02937649)
- Testing
- Laparoscopic sleeve gastrectomy using 48-Fr bougie, Laparoscopic sleeve gastrectomy using standard care bougie
- Where
- 12 sites in France
- Volunteers
- 1,658 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bariatric Surgery, Fat Free Mass
Protein Supplementation and Resistance Training to Prevent Fat-Free Mass Loss Following Metabolic-Bariatric Surgery
The goal of this clinical trial is to investigate the effects of daily protein supplementation and participation in a weekly supervised resistance training program on the prevention of excessive muscle mass loss following…
- Trial name
- ENRICHED (NCT07156552)
- Testing
- Resistance exercise training and protein supplementation
- Where
- 2 sites in Netherlands
- Volunteers
- 400 people
- Sponsor
- Radboud University Medical Center
Stomach Neoplasm
Omentum Preservation Versus Complete Omentectomy in Gastrectomy for Gastric Cancer
Curative therapy for gastric cancer usually consists of perioperative chemotherapy and a radical (R0) gastrectomy. A radical resection includes a modified D2 lymphadenectomy, and, generally, a complete omentectomy, to ensure the…
- Trial name
- OMEGA-2 (NCT05180864)
- Testing
- Gastrectomy
- Where
- 16 sites in Germany, Italy and 2 more
- Volunteers
- 654 people
- Sponsor
- Amsterdam UMC
Gastric Cancer
Frailty Assessment and Intervention in Elderly Patients with Gastric Cancer Receiving Gastrectomy and Adjuvant Chemotherapy
Gastric cancer ranks among the top ten leading causes of death in Taiwan. Radical surgery is the sole curative method for gastric cancer.
- Trial name
- NCT06055387
- Testing
- Frailty intervention measures
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Chang Gung Memorial Hospital
Gastrostomy, Gastric
Trans-Pacific Multicenter Collaborative Study of Minimally Invasive Proximal Versus Total Gastrectomy for Proximal Gastric and Gastroesophageal Junction Cancers
To compare the symptoms of patients who have a MIPG to the symptoms of patients who have a MITG.
- Conditions
- Gastrostomy, Gastric, GastroEsophageal Cancer
- Trial name
- NCT05205343
- Testing
- Standard of Care, Control Group
- Where
- 4 sites in United States, Japan and 1 more
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Gastric Cancer Stage, Gastric Cancer Patients Undergoing Gastrectomy
AI-Assisted Detection and Staging of Gastric Cancer Using Contrast-Enhanced CT
Accurate preoperative assessment of gastric cancer stage guides eligibility for endoscopic resection, extent of gastrectomy and lymphadenectomy, selection for neoadjuvant therapy, and use of staging laparoscopy.
- Trial name
- NCT07250347
- Testing
- CT scan
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Postprandial Hypoglycemia, End-stage Renal Disease (ESRD)
Anakinra for the Treatment of Postprandial Hypoglycemia in a Patient With Total Gastrectomy and End-Stage Renal Disease
Post-meal low blood sugar (postprandial hypoglycemia) is a common problem after certain stomach surgeries like gastric bypass or stomach removal.
- Conditions
- Postprandial Hypoglycemia, End-stage Renal Disease (ESRD), Gastrectomy, Glucose Metabolism Disorders
- Trial name
- AnPHy-ReD (NCT07580079)
- Testing
- Anakinra (interleukin-1 receptor antagonist)
- Where
- Switzerland
- Volunteers
- 1 people
- Sponsor
- Marc Donath
Post Operative Pain
Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy
The purpose of this study is to evaluate the use of an injectable combination of bupivacaine and meloxicam (Zynrelef) vs injectable liposomal bupivacaine (Exparel), two extended local anesthesia strategies currently approved by…
- Trial name
- NCT06349772
- Testing
- Zynrelef, Exparel
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Obesity
Comparison of Two Surgical Techniques for Treatment of Type III Obesity (BMI 40-50 kg/m2): Single Anastomosis Duodenoileal Bypass With Sleeve Gastrectomy and Roux-en-Y Gastric Bypass.
Roux-en-Y gastric bypass (RY-GBP) is one of the surgical techniques most widely used for the treatment of obesity. Long series of operated patients published in the literature have demonstrated its safety and efficacy.
- Trial name
- BYPSADIS (NCT06789965)
- Testing
- SADI-S, RY-GBP
- Where
- Spain
- Volunteers
- 450 people
- Sponsor
- Hospital Clinic of Barcelona
Gastric Cancer (GC), Adjuvant Chemotherapy
Adjuvant Oxaliplatin Plus S-1 Versus Docetaxel Plus S-1 for Stage III Gastric Cancer
This is a multicenter, open-label, phase 3, randomized, non-inferiority study aimed to investigate the effect on disease-free survival of adjuvant chemotherapy with oxaliplatin plus S-1 compared with adjuvant chemotherapy with…
- Conditions
- Gastric Cancer (GC), Adjuvant Chemotherapy, Stage 3 Cancer, Docetaxel
- Trial name
- NCT07366528
- Testing
- Oxaliplatin plus S-1, Docetaxel plus S-1
- Where
- 5 sites in China
- Volunteers
- 387 people
- Sponsor
- Ruijin Hospital
Time
Perioperative Analgesic Effect of Different Volumes of Modified Thoracoabdominal Perichondrial Approach on Patients Undergoing Sleeve Gastrectomy: Prospective Randomized Trial
Sleeve gastrectomy is a leading technique in metabolic \& bariatric surgery. It gained ever-increasing popularity among laparoscopic bariatric surgeries and has proved to be a successful method in achieving considerable weight…
- Trial name
- NCT07510347
- Testing
- Modified Thoracoabdominal Nerve Block through perichondrial approach (M-TAPA)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Iron Deficiency Anemia
Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical Patient
Given the limited long-term effectiveness of traditional weight loss methods, bariatric surgery is increasingly becoming the preferred option for sustained weight loss.
- Trial name
- NCT04268849
- Testing
- Ferumoxytol, Saline, Ferrous sulfate tablets
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Auerbach Hematology Oncology Associates P C