Clinical trials: Gastrectomy
Bariatric Surgery, Lidocaine
Intravenous Lidocaine Infusion Versus Intravenous Dexmedetomidine Infusion During Sleeve Gastrectomy
Although laparoscopic (LAP) bariatric surgery is minimally invasive. Following any laparoscopic procedure, patients typically experience the peak of postoperative pain within the first 24 hours.
- Conditions
- Bariatric Surgery, Lidocaine, Dexmedetomidine
- Trial name
- NCT07327905
- Testing
- intravenous lidocaine, intravenous dexmedetomidine
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Anastomotic Leak, Gastric Cancer
Anastomotic Leak Testing in Gastrectomy
Anastomotic leak after radical gastrectomy is a serious complication. Intraoperative leak testing was often used to assess the integrity of the anastomosis.
- Conditions
- Anastomotic Leak, Gastric Cancer, Surgery, Testing, Reality
- Trial name
- NCT04292496
- Testing
- Introperative leak testing
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Nanchong Central Hospital
Sleeve Gastrectomy, Obesity & Overweight
8-Year Outcomes After Sleeve Gastrectomy
Obesity is a major global public health concern, and bariatric surgery is recognized as the most effective treatment for achieving sustained weight loss and improving obesity-related comorbidities.
- Trial name
- NCT07348822
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Medipol University
Obesity, Bariatric Surgery Candidate
Crural Repair During Laparoscopic Sleeve Gastrectomy in Patients With a Lax Gastroesophageal Junction
Background: Laparoscopic sleeve gastrectomy (LSG) is one of the commonest bariatric procedures. However, it is associated with postoperative gastroesophageal reflux disease (GERD) and erosive esophagitis (EE).
- Conditions
- Obesity, Bariatric Surgery Candidate, Esophagus Injury, Gastroesophageal Reflux
- Trial name
- REPAIR (NCT05330910)
- Testing
- Laparoscopic sleeve gastrectomy with concomitant hiatal hernia repair arm, Laparoscopic sleeve gastrectomy arm
- Where
- 2 sites in Singapore
- Volunteers
- 96 people
- Sponsor
- Sengkang General Hospital
Gastric Cancer
The Effect of Prucalopride Succinate on Gastrointestinal Motility After Laparoscopic Gastrectomy : Prospective Double Blind Case-control Study
In order to improve postoperative ileus in patients undergoing gastrointestinal surgery, digestive medications and prokinetics have been routinely used.
- Trial name
- NCT05966246
- Testing
- Arm I : Experimental (Prucalopride succinate group), Arm II : Control (Mosapride citrate group)
- Where
- South Korea
- Volunteers
- 106 people
- Sponsor
- Gangnam Severance Hospital
Stomach Neoplasms, Indocyanine Green
Indocyanine Green Tracer Using in Laparoscopic Gastrectomy With Lymph Node Dissection
The purpose of this study is to explore the clinical outcomes of Indocyanine Green Tracer using in laparoscopic gastrectomy with lymph node dissection for gastric adenocarcinoma（cT1-4a, N-/+, M0）.
- Trial name
- ICGTinLG (NCT03050879)
- Testing
- Indocyanine Green Tracer
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Fujian Medical University
Gastric Cancer
Validation of a Model for Predicting Anastomotic Leakage
This study will validate a machine learning model for predicting anastomotic leakage of esophagogastrostomy and esophagojejunostomy.
- Trial name
- NCT05646290
- Where
- China
- Volunteers
- 512 people
- Sponsor
- Jichao Qin
Polycystic Ovary Syndrome, Severe Obesity
Effect of Metabolic Surgery on Live Birth Rate of Offspring in Obesity Polycystic Ovarian Syndrome Patients
This is a experimental study, which subjects are obese PCOS patients requiring LSG surgery. Aim to investigate the effects of LSG surgery in PCOS patients whether increases the live birth rate of the offspring.
- Conditions
- Polycystic Ovary Syndrome, Severe Obesity, Laparoscopic Sleeve Gastrectomy
- Trial name
- NCT04151459
- Testing
- Metformin
- Where
- China
- Volunteers
- 18 people
- Sponsor
- RenJi Hospital
Stomach Neoplasms, Validation Study
Spanish Validation of KOQUSS-40 Questionnaire: Assessing QoL of Gastric Cancer Patients After Gastrectomy: SPQUSS-41
The main objective of this study is the translation, linguistic adaptation into Spanish, and validation of the Korean quality of life questionnaire KOQUSS-40.
- Trial name
- SPQUSS-41 (NCT07504913)
- Testing
- Development Questionnaire and Validation Questionnaire
- Where
- 6 sites in Spain
- Volunteers
- 505 people
- Sponsor
- Parc de Salut Mar
Sleeve Gastrectomy
Crural Dissection in Sleeve Gastrectomy
The purpose of this study is to identify if there is a benefit in routine dissection of the diaphragmatic crura during sleeve gastrectomy.
- Trial name
- NCT04168060
- Testing
- Crura dissection, Sleeve gastrectomy, Hiatal hernia repair
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Miami
Quadratus Lumborum Block, Erector Spinae Plane Block
Analgesic Efficacy of Quadratus Lumborum Block Against Erector Spinae Plane Block in Laparoscopic Sleeve Gastrectomy
The current investigation aimed to assess the postoperative analgesic efficacy of quadratus lumborum block against erector spinae plane block in sleeve gastrectomy surgeries
- Conditions
- Quadratus Lumborum Block, Erector Spinae Plane Block, Sleeve Gastrectomy
- Trial name
- NCT06828497
- Testing
- Technique of posterior quadratus lumborum block (QL 2 block):, Technique of erector spinae plane block:
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Port Said University hospital
Robotic Gastrectomy, Stomach Neoplasms
Carina™ Surgical Platform for Minimal Radical Gastrectomy
To evaluate the safety and effectiveness of the laparoscopic surgical system（Carina™ Surgical Platform, developed by Ronovo Surgical, Inc) for use in gastrectomy.
- Trial name
- NCT07113340
- Testing
- Carina™ Surgical Platform, developed by Ronovo Surgical, Inc
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Gastroesophageal Reflux Disease (GERD)
Evaluation of the Effectiveness of the Ezisurg Stapling (Ezi Endo Lite) During Laparoscopic Nissen Sleeve Gastrectomy
The Nissen Sleeve technique consists of creating a gastric total fundoplication (Nissen technique) before to perform the removal of 2/3 of the stomach (SLEEVE technique), intends for decrease the rate of gastroesophageal reflux…
- Trial name
- NCT07344935
- Testing
- Ezisurg stapler SLEEVE technique, Ethicon Stapler SLEEVE technique
- Where
- France
- Volunteers
- 167 people
- Sponsor
- Ezisurg Medical Co. Ltd.
Bariatric Surgery
Physiological Responses to Laparoscopic Sleeve Gastrectomy: Focusing on Ghrelin
Our hypothesis is that decreased concentration of ghrelin after LSG is important for the decreased appetite and food intake postoperatively.
- Trial name
- NCT04055025
- Testing
- Ghrelin
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Pediatric Obesity
Medications After Adolescent Bariatric Surgery
This study will assess the feasibility to assess practicality of early weight loss medication usage in adolescent patients post-VSG with inadequate weight loss.
- Trial name
- MAABS Protocol (NCT04572217)
- Testing
- Topiramate, Phentermine
- Where
- United States
- Sponsor
- Janey Pratt
Obesity, Morbid, Obesity and Overweight
Identification of Pre-surgical Phenotypic Indicators Predictive of Quality of Life Trajectories in Obese Patients Following Bariatric Surgery
This study aims to identify pre-operative phenotypic determinants predictive of quality of life trajectories in post-bariatric surgery patients.
- Conditions
- Obesity, Morbid, Obesity and Overweight, Bariatric Surgery, Bariatric Surgery Patients
- Trial name
- PHENOBEQOL73 (NCT06951893)
- Testing
- Hospital Anxiety and Depression Scale, Dutch Eating Behaviour Questionnary, Impact of Weight on Quality Of Life
- Where
- France
- Volunteers
- 165 people
- Sponsor
- Centre Hospitalier Metropole Savoie
Impaired Renal Function
Effects of Obesity Surgery on Renal Function
Increasing risk of impaired renal function as a result of obesity is well known. Early data has postulated that weight loss might improve kidney function, but the evidence is rather limited due to the difficulties in measuring…
- Trial name
- NCT01507350
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- Imperial College London
Gastric Cancer
Curative D2 vs D1 Lymphadenectomy in Operable Gastric Carcinoma
Gastric carcinoma is the second most common cause of cancer-related deaths and its main treatment modality if potentially curable is surgery but the optimal surgical resection is controversial.
- Trial name
- NCT04340440
- Testing
- D1 lymphadenectomy, D2 lymphadenectomy
- Volunteers
- 80 people
- Sponsor
- University of Alexandria
Gastric Tumor
Impact of Roux-En-Y Pouch Reconstruction Compared With Conventional Roux-En-Y Reconstruction on Quality of Life in Patients Undergoing Total Gastrectomy
The purpose of this study is to find out more about differences of the quality of life in patients undergoing Roux-En-Y pouch reconstruction and conventional Roux-En-Y reconstruction.
- Trial name
- GCQOL02 (NCT01697943)
- Testing
- Roux-En-Y Pouch Reconstruction or Conventional Roux-En-Y Reconstruction
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Fudan University
Gastrointestinal Stromal Tumors
A Cohort Study on the Safety of Laparoscopic Resection of 5cm or Larger Gastric Gastrointestinal Stromal Tumors
The purpose of this study is to explore the safety of laparoscopic resection of 5cm or larger gastric gastrointestinal stromal tumors
- Trial name
- NCT05938309
- Where
- China
- Volunteers
- 194 people
- Sponsor
- Fujian Medical University