Clinical trials: Gastrectomy, active
Bariatric Surgery, Bariatric Sleeve Gastrectomy
Effects of the Dietary Inflammatory Index on Systemic Inflammation Markers and Gastrointestinal Symptoms in Individuals With Bariatric Surgery
The goal of this observational cross-sectional study is to evaluate the relationships between the Dietary Inflammatory Index (DII), systemic inflammatory markers, and gastrointestinal symptoms in adults aged 18-65 who have…
- Conditions
- Bariatric Surgery, Bariatric Sleeve Gastrectomy, Inflamation, Systemic Inflammation
- Trial name
- NCT07293624
- Testing
- Observational Intervention, Observetional
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul Bilgi University
Gastric Cancer, Surgery
Clinical Outcomes of Indocyanine Green Tracer Using in Laparoscopic Gastrectomy With Extended Lymphadenectomy Beyond D2 for Locally Advanced Gastric Cancer (FUGES-30)
Taking patients with locally advanced gastric adenocarcinoma (cT2-4a, N-/+, M0) as the research subjects, to evaluate whether the clinical efficacy of laparoscopic beyond D2 regional lymph node dissection for gastric cancer with…
- Trial name
- NCT06945718
- Testing
- beyond D2 regional lymph node dissection
- Where
- China
- Volunteers
- 760 people
- Sponsor
- Fujian Medical University
Early Gastric Cancer, Adenocarcinoma of the Stomach
SPADE Clinical Trial.
Purpose: This multicenter, prospective, single-arm phase 2 clinical trial aims to evaluate the safety, feasibility, and clinical outcomes of the SPADE operation (Spade-Shaped Anastomosis) in patients undergoing laparoscopic or…
- Conditions
- Early Gastric Cancer, Adenocarcinoma of the Stomach, Proximal Gastric Cancer, SPADE Operation
- Trial name
- SPADE (NCT07892183)
- Testing
- Spade-Shaped Anastomosis after Laparoscopic or Robotic Proximal Gastrectomy Using Double Suture Anchoring between the Posterior Wall of the Esophagus and the Anterior Wall of the Stomac
- Where
- South Korea
- Volunteers
- 159 people
- Sponsor
- National Cancer Center, Korea
Dynamic Lung Compliance
Effects of Changes in Driving Pressure on Intraoperative Pulmonary Dynamic Compliance and PaO₂/FiO₂ Ratio in Laparoscopic Sleeve Gastrectomy
The goal of this prospective intervention study is to determine whether individualized positive end expiratory pressure (PEEP) titration targeting the minimum Driving pressure (ΔP) during LGS operation improves intraoperative…
- Trial name
- PEEP (NCT07494240)
- Testing
- incremental peep
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Beni-Suef University
Gastric Adenocarcinoma, Surgery, Laparoscopic
Defining Benchmarks for Gastric Cancer Patients Underwent Minimal Invasive Gastrectomy
The Benchmark-MISGC study was a large-scale retrospective observational study launched by the China Gastric Cancer Surgical Union, aiming to establish the benchmarks of the short- and long-term outcomes for gastric cancer…
- Trial name
- NCT06938139
- Where
- China
- Volunteers
- 90,000 people
- Sponsor
- Fujian Medical University
Gastric Cancer, Peritoneal Metastases
HIPEC Combined Gastrectomy in Patients With Advanced Gastric Cancer Received Neoadjuvant Chemotherapy
Patients with stage cT3-4N+M0 gastric cancer were recommended to receive neoadjuvant chemotherapy before radical surgery in terms of the eradication of micrometastasis in addition to local control, higher compliance with…
- Trial name
- NCT05300945
- Testing
- HIPEC
- Volunteers
- 200 people
- Sponsor
- Zhixin Cao
Severe Obesity
Mazdutide as Adjuvant Therapy Following Sleeve Gastrectomy in Severe Obesity
The SMART study is a 96-week, multicenter, randomized, double-blind, placebo-controlled superiority clinical trial. A total of 256 severe obesity patients are randomized 1:1 to either receive the bariatric surgery plus GCG/GLP-1…
- Trial name
- SMART (NCT07135141)
- Testing
- Sleeve gastrectomy plus early mazdutide initiation
- Where
- 14 sites in China
- Volunteers
- 256 people
- Sponsor
- Beijing Friendship Hospital
Gastric Adenocarcinoma, Adenocarcinoma of the Esophagogastric Junction
Sino-Russian Comparison of Outcomes After Proximal Gastrectomy With Double-Tract Reconstruction
This two-center retrospective observational cohort study compares Chinese and Russian patients who underwent curative proximal gastrectomy with double-tract reconstruction for proximal gastric adenocarcinoma or Siewert type…
- Trial name
- RUSCHI-DTR (NCT07800819)
- Testing
- Proximal gastrectomy with double-tract reconstruction
- Where
- 2 sites in China, Russia
- Volunteers
- 250 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
STOMACH NEOPLASM, Robotic Surgical Procedures
Safety and Efficacy Evaluation of Single-Port Versus Multi-Port Robotic-Assisted Radical Distal Gastrectomy for Gastric Cancer
This multicenter randomized non-inferiority trial evaluates single-port versus multi-port robotic-assisted radical distal gastrectomy in patients with gastric cancer.
- Trial name
- NCT07828899
- Testing
- Single-Port Robot-Assisted Radical Distal Gastrectomy, Multi-Port Robot-Assisted Radical Distal Gastrectomy
- Where
- 5 sites in China
- Volunteers
- 212 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Gastroesophageal Reflux, Sleeve Gastrectomy
Post-sleeve Gastrectomy Gastroesophageal Reflux Disease Prediction
Researchers are trying to identify predictors for gastroesophageal reflux disease after sleeve gastrectomy.
- Conditions
- Gastroesophageal Reflux, Sleeve Gastrectomy, Bariatric Surgery Complication
- Trial name
- NCT04411823
- Testing
- EndoFLIP measurement
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Ultrasound, External Oblique Intercostal Plane Block
Ultrasound-Guided External Oblique Intercostal Plane Block Versus Subcostal Transversus Abdominis Plane Block For Perioperative Analgesia in Laparoscopic Sleeve Gastrectomy
This study aims to compare the analgesic efficacy, duration of analgesia, and overall opioid consumption between the external oblique intercostal plane (EOIP) block and subcostal transversus abdominis plane (TAP) block in…
- Conditions
- Ultrasound, External Oblique Intercostal Plane Block, Subcostal Transversus Abdominis Plane Block, Perioperative Analgesia
- Trial name
- NCT07366138
- Testing
- External oblique intercostal plane block, Subcostal transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Benha University
Obesity (Disorder), Metabolic Disorders
Hormonal and Microbiota Modulation After Endoscopic Sleeve Gastroplasty
Obesity is a chronic disease with a rapidly increasing prevalence, expected to affect up to 25% of the French population by 2030, and is associated with significant morbidity, mortality, and healthcare burden.
- Trial name
- HOVIGAMI-ESG (NCT07576777)
- Testing
- Laparoscopic sleeve gastrectomy, Endoscopic sleeve gastroplasty
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gastrectomy, Postoperative Analgesia
Efficacy and Safety of Anrikefon Injection for the Treatment of Postoperative Pain in Patients Undergoing Totally Laparoscopic Radical Distal Gastrectomy
Anruikefen is a peripherally highly selective kappa receptor agonist that does not easily cross the blood-brain barrier, resulting in a low incidence of central adverse reactions such as respiratory depression, sedation, and…
- Trial name
- NCT07330063
- Testing
- Anruikefen (Intravenous Bolus), Anruikefen (Intravenous Infusion)
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Gastric Cancer
Efficacy of RUS GA Surgical Navigation for Robot-assisted Distal Gastrectomy in Gastric Cancer Patients
This investigator-initiated, randomized superiority clinical trial aims to demonstrate the clinical effectiveness of RUS GA Surgical Navigation, an endoscopic imaging treatment planning software, in patients undergoing…
- Trial name
- NCT06639490
- Testing
- RUS GA, standard treatment
- Where
- South Korea
- Volunteers
- 330 people
- Sponsor
- Yonsei University
Obesity & Overweight, Gastroesophageal Reflux (GERD)
Transit Bipartition After Sleeve Gastrectomy
This prospective, single-center study will evaluate adults undergoing revisional conversion from sleeve gastrectomy to intestinal transit bipartition.
- Conditions
- Obesity & Overweight, Gastroesophageal Reflux (GERD), Weight Recurrence, Bariatric Surgery
- Trial name
- BTT-SLEEVE (NCT07728682)
- Testing
- Conversion to Intestinal Transit Bipartition
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Hospital das Clínicas de Ribeirão Preto
Gastric Cancer, Diabetes Mellitus, Type 2
Surgical TreAtment for Obesity Related Disease and Onco-Metabolic Surgery
This is a prospective, multi-center, randomized controlled trial to compare Billroth II reconstruction versus conventional Roux-en-Y reconstruction versus long limb Roux-en-Y reconstruction for glycemic control in patients with…
- Trial name
- STARDOM (NCT04284943)
- Testing
- Long limb Roux-en-Y reconstruction after subtotal gastrectomy, Conventional Roux-en-Y reconstruction after subtotal gastrectomy, Billroth II reconstruction after subtotal gastrectomy
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Korea University Anam Hospital
Gastric Cancer Patients Undergoing Gastrectomy
Single-port Robotic Radical Gastrectomy for Gastric Cancer
This study is a single-center, phase 2a exploratory clinical study based on IDEAL framework. The intraoperative and postoperative complications were analyzed to evaluate the safety, feasibility and clinical efficacy of…
- Trial name
- NCT07237126
- Testing
- Single-port Robotic Radical Gastrectomy for Gastric Cancer
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Gastric Cancer
OGT-assisted Overlap Esophagojejunostomy Versus Traditional Overlap Method
Abstract Background Our previous studies have shown OGT method significantly simplified overlap esophagojejunostomy with good short-term outcomes, and provided new perspectives for optimizing esophagojejunostomy.
- Trial name
- OGT (NCT05450835)
- Testing
- OGT group, Overlap group
- Where
- 12 sites in China
- Volunteers
- 344 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Gastroparesis Postoperative, Delayed Gastric Emptying Following Procedure
Acupuncture for Postoperative Gastric Emptying Delay
This multicenter clinical trial, conducted at Qilu Hospital of Shandong University and collaborating institutions, prospectively assesses the efficacy and safety of acupuncture for postoperative delayed gastric emptying.
- Trial name
- APOGEE (NCT07505927)
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Qilu Hospital of Shandong University
Obesity, Morbid, Obesity and Overweight
Identification of Pre-surgical Phenotypic Indicators Predictive of Quality of Life Trajectories in Obese Patients Following Bariatric Surgery
This study aims to identify pre-operative phenotypic determinants predictive of quality of life trajectories in post-bariatric surgery patients.
- Conditions
- Obesity, Morbid, Obesity and Overweight, Bariatric Surgery, Bariatric Surgery Patients
- Trial name
- PHENOBEQOL73 (NCT06951893)
- Testing
- Hospital Anxiety and Depression Scale, Dutch Eating Behaviour Questionnary, Impact of Weight on Quality Of Life
- Where
- France
- Volunteers
- 165 people
- Sponsor
- Centre Hospitalier Metropole Savoie