Clinical trials: Gastrectomy for Gastric Cancer
Gastric Cancer
Safety Comparison of Total Laparoscopic Proximal Gastrectomy With or Without Preservation of the Celiac Branch of the Vagus Nerve for Early Upper Gastric Cancer: A Randomized Controlled Clinical Trial
This prospective, single-center, randomized, controlled, non-inferiority clinical trial aims to compare the safety and postoperative quality of life of early upper gastric cancer patients undergoing total laparoscopic proximal…
- Trial name
- TLPG-CBVP (NCT07142122)
- Testing
- Total laparoscopic proximal gastrectomy with preservation of both the hepatic and celiac branches of the vagus nerve, followed by double-tract reconstruction., Total laparoscopic proximal gastrectomy with preservation of the hepatic branch of the vagus nerve but deliberate resection of the celiac branch, followed by double-tract reconstruction.
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Fujian Cancer Hospital
Gastric or Esophagogastric Junction Adenocarcinoma
PD1 Combined With Chemotherapy for Adjuvant Treatment of Gastric Cancer
This multicenter, randomized, double-blind phase III study intends to recruit about 878 patients, including PD-L1 positive 660 patients, who have received radical gastrectomy (R0 resection, D2 or more extended lymphadenectomy)…
- Trial name
- NCT05180734
- Where
- 71 sites in China
- Volunteers
- 878 people
- Sponsor
- Shanghai Junshi Bioscience Co., Ltd.
Gastric Cancer, Surgery
3D-4K-ICG Laparoscopic Gastrectomy for Gastric Cancer
Patients with locally advanced gastric adenocarcinoma (CT2-4a N-/+ M0) were selected as study subjects to investigate the safety, efficacy, and feasibility of ICG near-infrared imaging tracing in 3D plus ultra high resolution…
- Trial name
- 3D-4K-ICG (NCT06161207)
- Testing
- Indocyanine Green Tracer Using in 3D plus Ultra High Resolution Laparoscopic Gastrectomy with Lymph Node Dissection
- Where
- China
- Volunteers
- 702 people
- Sponsor
- Fujian Medical University
Gastric Cancer, Postoperative Complications
Comparative Study of Antiperistaltic vs Isoperistaltic Billroth II + Braun Anastomosis for Postoperative Reflux
Postoperative gastroesophageal reflux is one of the most common complications of distal gastrectomy. With more attention paid on it by surgeons, several new operation methods have been practised.
- Trial name
- NCT03372681
- Testing
- Isoperistaltic Billroth II + Braun anastomosis, Antiperistaltic Billroth II + Braun anastomosis
- Volunteers
- 214 people
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Gastric Cancer, Esophagogastric Junction Disorder
Severe Complications After Gastrectomy for Esophagogastric Junction and Gastric Cancer
Gastrectomy is the main treatment for gastric and Siewert type II-III esophagogastric junction (EGJ) cancer. This surgery is associated with significant morbidity.
- Trial name
- NCT03909997
- Where
- Chile
- Volunteers
- 300 people
- Sponsor
- Hospital Dr Sotero del Rio
Gastric Cancer
NuGa (Nutrition for Gastric Cancer Patients)
The objective of this pilot study is to evaluate the feasibility and efficacy of Rhexium Onco Nutrition, HDT-202 for post-operative care in patients who have undergone gastrectomy.
- Trial name
- NCT04800991
- Testing
- Rhexium Onco Nutrition
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Gastric Adenocarcinoma, Esophagogastric Junction
Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology
Background: Gastric cancer is a common and serious cancer. Standard treatment is chemotherapy drugs. Researchers want to see if a new treatment helps.
- Conditions
- Gastric Adenocarcinoma, Esophagogastric Junction, Gastric Cancer
- Trial name
- NCT03092518
- Testing
- Surgery, Cisplatin, Mitomycin C
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- National Cancer Institute (NCI)
Gastric Cancer, Enteral Immunonutrition
Effect of Enteral Immunonutrition on Immune, Inflammatory Markers and Nutritional Status in Patients Undergoing Gastrectomy for Gastric Cancer
Enteral immunonutrition (EIN) has been gaining increasing attention, but data of its immune and anti-inflammatory function in patients undergoing gastrectomy for gastric cancer are poorly investigated.
- Trial name
- NCT03730545
- Testing
- enteral immunonutrition
- Volunteers
- 124 people
- Sponsor
- West China Hospital
Early Gastric Cancer, Indocyanine Green
Indocyanine Green Tracer Using in Laparoscopic Distal Gastrectomy for Early Gastric Cancer
This study aims to explore the value of indocyanine green (ICG) in laparoscopic distal gastrectomy with lymph node dissection for early gastric cancer.The patients with early gastric adenocarcinoma (cT1, N-/+, M0) will be studied.
- Conditions
- Early Gastric Cancer, Indocyanine Green, Lymph Node Dissection
- Trial name
- NCT04973475
- Testing
- Indocyanine Green
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Fujian Medical University
Gastric Cancer
Long-term Outcomes of Open Versus Laparoscopic Distal Gastrectomy for T4a Gastric Cancer
There are more than 75% of patients with gastric cancer who are diagnosed in advanced stage in Vietnam, most of cases in T4a. The purpose of this study was to compare short- and long- term outcomes of open and laparoscopic distal…
- Trial name
- NCT05493358
- Testing
- Laparoscopic distal gastrectomy
- Where
- Vietnam
- Volunteers
- 472 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Gastric Cancer
Prehabilitation for Gastrectomy
Prehabilitation has been demonstrated to be an effective strategy to improve outcomes in patients undergoing some of the abdominal operations.
- Trial name
- PREFOG (NCT04223401)
- Testing
- Prehabilitation
- Where
- 2 sites in Lithuania
- Volunteers
- 128 people
- Sponsor
- National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos
Quality of Life, Gastric Cancer
Comparing the Quality of Life Between LADG and TLDG for Gastric Cancer_KLASS07 (CKLASS01)).
The present randomized study is designed to compare the quality of life between the patients undergoing laparoscopy-assisted and totally laparoscopic distal gastrectomy for gastric cancer, and therefore to evaluate the…
- Conditions
- Quality of Life, Gastric Cancer, Surgery, Surgical Complication
- Trial name
- NCT03393182
- Testing
- TLDG arm, LADG arm
- Where
- South Korea
- Volunteers
- 443 people
- Sponsor
- Korea University Anam Hospital
Gastric Cancer
T- XELOX in HER2-positive Stage III Gastric Cancer After D2 Gastrectomy
The objective of this study is to assess the clinical efficacy and safety of trastuzumab plus XELOX for treatment of HER2-positive Stage III Gastric Cancer After D2 Gastrectomy.
- Trial name
- NCT02250209
- Testing
- Trastuzumab, Capecitabine, Oxaliplatin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Chinese PLA General Hospital
Gastric Cancer (GC), Adjuvant Chemotherapy
Adjuvant Oxaliplatin Plus S-1 Versus Docetaxel Plus S-1 for Stage III Gastric Cancer
This is a multicenter, open-label, phase 3, randomized, non-inferiority study aimed to investigate the effect on disease-free survival of adjuvant chemotherapy with oxaliplatin plus S-1 compared with adjuvant chemotherapy with…
- Conditions
- Gastric Cancer (GC), Adjuvant Chemotherapy, Stage 3 Cancer, Docetaxel
- Trial name
- NCT07366528
- Testing
- Oxaliplatin plus S-1, Docetaxel plus S-1
- Where
- 5 sites in China
- Volunteers
- 387 people
- Sponsor
- Ruijin Hospital
Gastric Cancer, Gastrectomy
Laparoscopic Spleen-Preserving No. 10 Lymph Node Dissection for AGC
The purpose of this study is to explore the safety and feasibility of laparoscopic spleen-preserving No. 10 lymph node dissection for patients with advanced middle or upper third gastric cancer.
- Conditions
- Gastric Cancer, Gastrectomy, Laparoscopic Surgery, Lymphadenectomy
- Trial name
- NCT03708783
- Testing
- laparoscopic Spleen-Preserving No. 10 Lymph Node Dissection
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Peking University Cancer Hospital & Institute
Gastric Cancer Stage, Gastric Cancer Patients Undergoing Gastrectomy
AI-Assisted Detection and Staging of Gastric Cancer Using Contrast-Enhanced CT
Accurate preoperative assessment of gastric cancer stage guides eligibility for endoscopic resection, extent of gastrectomy and lymphadenectomy, selection for neoadjuvant therapy, and use of staging laparoscopy.
- Trial name
- NCT07250347
- Testing
- CT scan
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Gastric Cancer
Laparoscopic Versus Open Lower Mediastinal Lymphadenectomy for Esophagogastric Junction Cancer
Mediastinal lymph node dissection has been adopted as standard treatment for adenocarcinoma of esophagogastric junction(AEJ). This multi-center, exploratory, prospective, cohort study aims at provide standard technical details of…
- Trial name
- NCT04443478
- Testing
- Radical gastrectomy with dissection of lower mediastinal lymph node
- Where
- China
- Volunteers
- 1,036 people
- Sponsor
- Peking University
Gastrectomy for Gastric Cancer
Lymph Node Staging System With a Novel Concept for Gastric Cancer: a Hybrid Type of Topographic and Numeric Ones
For staging the status of lymph node metastasis in gastric cancer, typographic based staging system was applied until last decade, especially in Eastern countries.
- Trial name
- NCT01961791
- Testing
- gastrectomy
- Where
- South Korea
- Volunteers
- 6,025 people
- Sponsor
- Yonsei University
Gastric Cancer
ERAS for Gastric Cancer Patients After NACT
Background: Gastric cancer patients receiving neoadjuvant chemotherapy (NACT) are more vulnerable to perioperative stress. Enhanced recovery after surgery (ERAS) is widely used in surgical patients aiming at reducing stress…
- Trial name
- NCT06365814
- Testing
- enhanced recovery after surgery, conventional perioperative management
- Where
- China
- Volunteers
- 252 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Gastric Cancer
NBI for Identifying Resection Margin Status in Gastric Cancer
As the proportion of early gastric cancer has been steadily increased in Korea, so has function-preserving surgery. The function preserving surgery is characterized by the minimized extent of gastrectomy, so this implies that…
- Trial name
- NCT02926716
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Ajou University School of Medicine