Clinical trials: Gastrectomy for Gastric Cancer
Gastric Cancer, Surgery
Ultrasonic Scalpel vs. Monopolar Electrocautery for D2 Distal Gastric Carcinoma Surgery
Gastric cancer as one of the most common gastrointestinal cancers, radical resection of primary lesions combined with dissection of regional lymph-nodes is acknowledged by surgeons all over the world.
- Conditions
- Gastric Cancer, Surgery, Ultrasonic Scalpel, Monopolar Electrocautery
- Trial name
- CGCT-01 (NCT02130752)
- Testing
- Monopolar electrocautery, Ultrasonic scalpel
- Where
- 9 sites in China
- Volunteers
- 430 people
- Sponsor
- West China Hospital
Gastric Cancer, Stomach Cancer
A Study Comparing Billroth II With Roux-en-Y Reconstruction for Gastric Cancer
Both Billroth II and Roux en Y are acceptable techniques of reconstruction after subtotal gastrectomy, however the debate one which is better remains unanswered.
- Conditions
- Gastric Cancer, Stomach Cancer, Gastrectomy
- Trial name
- SCAR (NCT01257711)
- Testing
- Roux-en-Y or Billroth II
- Where
- 4 sites in Hong Kong, Singapore
- Volunteers
- 96 people
- Sponsor
- National Healthcare Group, Singapore
Gastric Cancer, Gastrostomy
Function Preserving Gastrectomy for T1/2 Gastric Cancer Patients
The real world based multi-cohorts study aims to evaluate the safety and effectiveness of function preserving gastrectomy including pylorus-preserving distal gastrectomy, proximal gastrectomy and wedge gastrectomy for T1 and T2…
- Trial name
- NCT03874871
- Testing
- Function preserving gastrectomy, Standard gastrectomy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University
Gastric Cancer (Diagnosis), Gastrectomy
The UGIRA International Registry for RAMIG for Gastric Cancer
Minimally invasive gastrectomy (MIG) has gained in popularity, since it is feasible, safe and oncologically comparable to open gastrectomy, while morbidity and duration of hospitalization are reduced, quality of life is…
- Trial name
- NCT07517432
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- Chinese University of Hong Kong
Gastric Cancer
Neoadjuvant Chemotherapy for Patients With Advanced Gastric Cancer in ERAS Programs for Radical Gastrectomy
Patients with advanced gastric cancer received neoadjuvant chemotherapy undergo enhanced recovery after surgery (ERAS) programs.
- Trial name
- NCT03238404
- Testing
- NAC group, Surgery alone group
- Where
- China
- Volunteers
- 88 people
- Sponsor
- JIANG Zhi-Wei
Gastric Cancer, Roux-en-y Anastomosis Site
Roux-en-Y vs. Roux-en-Y+ Pouch for D2 Total Gastrectomy
Gastric is one of the most prevalence digestive malignance tumors in China. Radical resection of primary tumors and combine with dissection of regional lymph-nodes is acknowledged by surgeons all over the world.
- Conditions
- Gastric Cancer, Roux-en-y Anastomosis Site, Gastric Anastomosis (Site), Quality of Life
- Trial name
- WCGCC-1202 (NCT02110628)
- Testing
- Roux-en-Y anastomosis, Roux-en-Y+Pouch anastomosis
- Where
- 9 sites in China
- Volunteers
- 588 people
- Sponsor
- West China Hospital
STOMACH NEOPLASM, Robotic Surgical Procedures
Safety and Efficacy Evaluation of Single-Port Versus Multi-Port Robotic-Assisted Radical Distal Gastrectomy for Gastric Cancer
This multicenter randomized non-inferiority trial evaluates single-port versus multi-port robotic-assisted radical distal gastrectomy in patients with gastric cancer.
- Trial name
- NCT07828899
- Testing
- Single-Port Robot-Assisted Radical Distal Gastrectomy, Multi-Port Robot-Assisted Radical Distal Gastrectomy
- Where
- 5 sites in China
- Volunteers
- 212 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Esophagojejunal Anastomotic Leak
Impact of Endo-vac Therapy for Esophago-jejunal Anastomotic Leak
The goal of this observational study is to assess the impact of endoscopic vacuum therapy in patients who underwent total gastrectomy due to gastric cancer and developed esophago-jejunal anastomotic leakage.
- Trial name
- ENDO-VAL (NCT07295236)
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Clinical Oncology
Gastric Cancer
Dual-Port Laparoscopic Distal Gastrectomy for Gastric Cancer
Dual-port laparoscopic gastrectomy (DPLG) has been widely performed in recent years for treating gastric cancers. The present study explore the safety and effect of dual-port laparoscopic distal gastrectomy (DPLDG).
- Trial name
- NCT05494086
- Testing
- DPLDG, LDG
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Gastric Cancer, GastroEsophageal Cancer
A Study of Minimally Invasive Proximal Gastrectomy Versus Minimally Invasive Total Gastrectomy for Gastric and Gastroesophageal Junction Cancers
Participants will a diagnosis of gastroesophageal junction (GEJ) adenocarcinoma and will have either a minimally invasive proximal gastrectomy (MIPG) or a minimally invasive total gastrectomy (MITG) as part of their routine care.
- Conditions
- Gastric Cancer, GastroEsophageal Cancer, Gastroesophageal Junction Adenocarcinoma
- Trial name
- NCT06243757
- Testing
- MDASI-GI
- Where
- 8 sites in United States
- Volunteers
- 4 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Gastric Cancer, Laparoscopic Gastrectomy
Outcomes of Laparoscopic Gastrectomy
A prospective study of the results of laparoscopic approach of gastric carcinoma in western patients is designed. The working hypothesis proposes obtaining similar results to those obtained in the series reported by eastern…
- Trial name
- NCT04652986
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Juan Carlos Martín del Olmo
Gastric Cancer
Intraoperative Adverse Events in Robotic Radical Gastrectomy for Gastric Cancer
Surgical quality control is a crucial determinant of evaluating the tumor efficacy. We assess the ClassIntra grade for quality control and oncological outcomes of robotic radical surgery for gastric cancer (GC).
- Trial name
- NCT05999019
- Testing
- robotic surgery
- Volunteers
- 366 people
- Sponsor
- Fujian Medical University
Early Gastric Cancer
Endoscopic Submucosal Dissection Versus Gastrectomy
Gastrectomy is curative treatment for early gastric cancer (EGC). Recently, endoscopic submucosal dissection (ESD) has been accepted as standard treatment in selected patients with negligible risk of lymph node metastasis.
- Trial name
- NCT02216110
- Testing
- Surgery
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Soonchunhyang University Hospital
Gastric Cancer
Comparative Analysis of Short-Term Therapeutic Effects Between the π-Shaped and Overlap Methods for Esophagogastrostomy in Totally Laparoscopic Total Gastrectomy
As of now, although the safety of π-shaped anastomosis and the overlap method has been separately discussed in different contexts, there have been few studies considering a direct comparison of the results of these two methods.
- Trial name
- NCT06383793
- Testing
- overlap
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Northern Jiangsu People's Hospital
Stomach Adenocarcinoma, Gastro-esophageal Junction Cancer
Preoperative HFRT Verses PULSAR for Locally Advanced GEJ or Proximal Gastric Adenocarcinoma
The goal of this clinical trial is to evaluate the efficacy and safety of the multimodal treatment, which includes radiotherapy, chemotherapy and anti-PD-1 immunotherapy. The trial is designed using a pick-the-winner strategy.
- Trial name
- TORCH-G (NCT06728657)
- Testing
- HFRT targeted to the primary lesion and positive lymph nodes, PULSAR targeted to the primary lesion and positive lymph nodes, Anti-PD-1 monoclonal antibody
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Fudan University
Gastric Cancer, Gastric Adenocarcinoma
Feasibility Study of Middle Segmental Gastrectomy (MSG) for Gastric Cancer.
This multicenter, prospective, single-arm phase 2 clinical trial aims to evaluate the safety, feasibility, and clinical applicability of Middle Segmental Gastrectomy (MSG) for patients with gastric cancer MSG is a…
- Conditions
- Gastric Cancer, Gastric Adenocarcinoma, Middle Segmental Gastrectomy (MSG), Function-preserving Surgery
- Trial name
- MSG (NCT07899697)
- Testing
- Totally Laparoscopic Middle Segmental Gastrectomy (TLMSG)
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- National Cancer Center, Korea
Gastric Cancer
Evaluation of the Efficacy of Distal Gastrectomy for the Treatment of Gastric Cancer (a Case Series)
Case series of a retrospective study of patients operated for distal adenocarcinoma of the stomach, either by total gastrectomy or distal gastrectomy at Ibn Rochd University Hospital in Casablanca, with the analysis of outcome of…
- Trial name
- NCT05068635
- Volunteers
- 30 people
- Sponsor
- Sylvestre KABURA
Stomach Neoplasms
Robotic Total Gastrectomy for Locally Advanced Proximal Gastric Cancer
The purpose of this study is to explore the clinical Efficacy of robotic assisted spleen-preserving No. 10 lymph node dissection for patients with locally advanced upper third gastric adenocarcinoma（cT2-4a, N-/+, M0）.
- Trial name
- NCT03524287
- Testing
- Robotic Assisted No.10 Lymph Node Dissections
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Fujian Medical University
Vitamin B12 Deficiency
Oral Vitamin B12 Administration for Vitamin B12 Deficiency After Total Gastrectomy
Pernicious anemia develops in 50% of total gastrectomized due to gastric cancer patients. Lack of intrinsic factor, which is secreted by parietal cell from stomach wall causes deficiency of cobalamin, which, in final, causes…
- Trial name
- NCT00699478
- Testing
- mecobalamin
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Gastric Cancer (GC)
Robotic vs Laparoscopic Gastrectomy for cT4a Gastric Cancer
The goal of this multicenter, randomized, phase III clinical trial is to test whether robot-assisted radical gastrectomy improves 3-year recurrence-free survival versus laparoscopy-assisted radical gastrectomy in adults aged…
- Trial name
- NCT07331454
- Testing
- Robotic Gastrectomy, Laparoscopic Gastrectomy
- Where
- China
- Volunteers
- 335 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University