Clinical trials: Gastrectomy for Gastric Cancer
Gastric Cancer
Clinical Trials for the Prevention of Gallstone Formation After Gastrectomy in Patient With Gastric Cancer
This study evaluates the efficacy and safety of DWJ1319 in the prevention of gallstone formation after gastrectomy in patient with gastric cancer.
- Trial name
- NCT02490111
- Testing
- DWJ1319
- Where
- 12 sites in South Korea
- Volunteers
- 521 people
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Gastric Cancer
The Advantages and Disadvantages of Linear Anastomat and Tubular Anastomat in Radical Gastrectomy of Distal Gastric Cancer
The goal of this clinical trial is to observe and compare the short-term complications, long-term survival and quality of life of linear anastomat and tubular anastomat during digestive tract reconstruction after resection of…
- Trial name
- NCT07080879
- Testing
- Linear Anastomat, Tubular Anastomat
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Xiangya Hospital of Central South University
Gastric Cancer (GC)
Robotic vs Laparoscopic Gastrectomy for cT4a Gastric Cancer
The goal of this multicenter, randomized, phase III clinical trial is to test whether robot-assisted radical gastrectomy improves 3-year recurrence-free survival versus laparoscopy-assisted radical gastrectomy in adults aged…
- Trial name
- NCT07331454
- Testing
- Robotic Gastrectomy, Laparoscopic Gastrectomy
- Where
- China
- Volunteers
- 335 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Gastric Cancer, Peritoneal Metastases
Neoadjuvant Systemic and Peritoneal Chemotherapy for Advanced Gastric Cancer
Data demonstrating the efficacy of PIPAC in patients with regionally advanced gastric cancer with positive peritoneal cytology and/or minimal peritoneal disease is limited due to the relatively recent development of this…
- Conditions
- Gastric Cancer, Peritoneal Metastases, Chemotherapy Effect
- Trial name
- SPECTRA (NCT05318794)
- Testing
- Doxorubicin and Cisplatin
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Imperial College London
Gastric Cancer
Laparoscopic Versus Open Gastrectomy for Gastric Cancer
This is the first randomized controlled trial comparing laparoscopic and open gastrectomy for resectable gastric cancer in a Western population.
- Trial name
- LOGICA (NCT02248519)
- Testing
- Open Gastrectomy, Laparoscopic Gastrectomy
- Where
- 10 sites in Netherlands
- Volunteers
- 210 people
- Sponsor
- UMC Utrecht
Gastric Cancer
Pilot Study for High Output Drainage Removal After Gastrectomy
*Objective: The study aims to evaluate whether there is a difference in intra-abdominal complication rates between patients discharged with or without a drainage tube following gastrectomy with high postoperative drainage…
- Trial name
- NCT06690112
- Testing
- Arm I (Drainage tube removal)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Gangnam Severance Hospital
Gastric Adenocarcinoma Patients, Who Are Scheduled for Laparoscopic Radical Gastrectomy
Comparison of Safety and Clinical Effects of Straight and Articulated Instruments (ArtiSential) in Laparoscopic Gastrectomy for Gastric Cancer Patients, a Prospective Randomized Study
In patients with gastric cancer, gastrectomy can be performed via laparoscopic/robotic or open surgery. It is crucial to completely remove the tumor along with an adequate extent of lymph node dissection.
- Trial name
- NCT07100431
- Testing
- Articulating (experimental group), Control (control group)
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Gangnam Severance Hospital
Early Gastric Cancer
Pure Single Incision Laparoscopic Distal Gastrectomy (SIDG) Versus Totally Laparoscopic Distal Gastrectomy (TLDG)
1. Compare the immune response and postoperative complications between pure SIDG (single-incision laparoscopic distal gastrectomy) and TLDG (totally laparoscopic distal gastrectomy) for early gastric cancer (EGC) 2.
- Trial name
- NCT01938326
- Testing
- Approach Method
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Bundang Hospital
Gastric Cancer
A Trial of Reconstruction After Distal Gastrectomy for Gastric Cancer
The purpose of this study is to evaluate the quality of life (QOL) after Billroth-I reconstruction (B-I) following distal gastrectomy, compared with Roux-en Y reconstruction (R-Y) in patients with gastric cancer.
- Trial name
- NCT01065688
- Testing
- Roux-en Y reconstruction, Billroth-I reconstruction
- Where
- Japan
- Volunteers
- 120 people
- Sponsor
- Wakayama Medical University
Gastric Cancer, ERAS
ERAS in Totally Laparoscopic Total Gastrectomy for Gastric Cancer
The number of totally laparoscopic total gastrectomy is gradually increasing, but the safety of ERAS in these term is still unknown and further multicenter randomized controlled studies are needed.
- Conditions
- Gastric Cancer, ERAS, Laparoscopic Gastrectomy
- Trial name
- NCT06489288
- Testing
- ERAS protocol
- Where
- China
- Volunteers
- 2,656 people
- Sponsor
- Xijing Hospital
Gastric Cancer
Propofol EC50 for Inducing Loss of Consciousness in General Combined Epidural Anesthesia
The beneficial of perioperative usage of thoracic epidural anesthesia and analgesia in various thoracic and upper abdominal surgery are well studied.
- Trial name
- NCT05124704
- Testing
- 5-8ml 0.375% ropivacaine, 5-8ml normal saline
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wang Jiangling
Gastrectomy for Gastric Cancer, Robotic Surgical Procedures
Assessment of Robotic Versus Laparoscopic Gastrectomy for GC Patients With Intraoperative Technical Complexity
While robotic gastrectomy (RG) is increasingly used in gastric cancer surgery, its potential advantages over laparoscopic gastrectomy (LG) in Intraoperative technical complexity (ITC) cases remain debated.
- Conditions
- Gastrectomy for Gastric Cancer, Robotic Surgical Procedures, Laparoscopic Surgical Procedures
- Trial name
- NCT06752538
- Where
- China
- Volunteers
- 3,534 people
- Sponsor
- Fujian Medical University
Stomach Neoplasm, Cardiovascular Diseases
Pharmacokinetics of Oral Antiplatelet Agents After Distal Gastrectomy
This study is aimed to investigate the changes in pharmacokinetics and efficacy of antiplatelet agents before and after distal gastrectomy in gastric cancer patients taking oral antiplatelet agents for primary or secondary…
- Conditions
- Stomach Neoplasm, Cardiovascular Diseases, Cerebrovascular Disease
- Trial name
- NCT05543863
- Testing
- Platelet function testing
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Kyungpook National University Chilgok Hospital
Gastric Cancer
ERAS for Gastric Cancer Patients After NACT
Background: Gastric cancer patients receiving neoadjuvant chemotherapy (NACT) are more vulnerable to perioperative stress. Enhanced recovery after surgery (ERAS) is widely used in surgical patients aiming at reducing stress…
- Trial name
- NCT06365814
- Testing
- enhanced recovery after surgery, conventional perioperative management
- Where
- China
- Volunteers
- 252 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Gastric Cancer
Validation of a Model for Predicting Anastomotic Leakage
This study will validate a machine learning model for predicting anastomotic leakage of esophagogastrostomy and esophagojejunostomy.
- Trial name
- NCT05646290
- Where
- China
- Volunteers
- 512 people
- Sponsor
- Jichao Qin
Gastric Adenocarcinoma, Esophagogastric Junction
Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology
Background: Gastric cancer is a common and serious cancer. Standard treatment is chemotherapy drugs. Researchers want to see if a new treatment helps.
- Conditions
- Gastric Adenocarcinoma, Esophagogastric Junction, Gastric Cancer
- Trial name
- NCT03092518
- Testing
- Surgery, Cisplatin, Mitomycin C
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- National Cancer Institute (NCI)
Gastric Adenocarcinoma, Stomach Neoplasms
Conversion Therapy Plus Surgery and Radiotherapy for Retroperitoneal Nodal Metastases in Gastric Cancer
This is a randomized, controlled, multicenter phase II clinical trial evaluating the efficacy and safety of conversion therapy combined with radical gastrectomy and adjuvant radiotherapy targeting para-aortic (station 16) lymph…
- Trial name
- NCT07007182
- Testing
- SOX regimen, CAPEOX regimen, PD-1 inhibitor
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Jinbo Yue
Gastroesophageal Junction Cancer, Stomach Neoplasms
Proximal Versus Total Gastrectomy for Locally Advanced Siewert Type II-III Gastroesophageal Junction Cancer
This multicenter prospective randomized clinical trial aims to compare the safety and oncological effectiveness of proximal gastrectomy and total gastrectomy in patients with locally advanced Siewert type II-III gastroesophageal…
- Conditions
- Gastroesophageal Junction Cancer, Stomach Neoplasms, Esophageal Neoplasms
- Trial name
- SIEWERT-RCT (NCT07482566)
- Testing
- Proximal Gastrectomy, Total Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Nurettin Şahin
Gastric Cancer
Comparison of Laparoscopic Versus Open Gastrectomy for Gastric Cancer: A Prospective Randomized Trial
The purpose of this study is to assess the usefulness of laparoscopic surgery for gastric cancer in comparison with open gastrectomy.
- Trial name
- KLASS (NCT00452751)
- Testing
- laparoscopy-assisted distal gastrectomy, open distal gastrectomy
- Where
- 16 sites in South Korea
- Volunteers
- 1,400 people
- Sponsor
- National Cancer Center, Korea
Gastric Cancer
Fast Track Surgery With Laparoscopic-assisted Gastrectomy for Advanced Gastric Cancer: a Randomized Controlled Trial
The purpose of this study is to to investigate the feasibility and safety of fast-track surgery when combined with laparoscopic-assisted gastrectomy for advanced gastric cancer patients.
- Trial name
- FTSlapAG (NCT01955096)
- Testing
- fast-track surgery, conventional postoperative care
- Volunteers
- 61 people
- Sponsor
- Quan Wang