Clinical trials: Gastrectomy for Gastric Cancer
Gastric Cancer
A Phase II Clinical Trial of Reduced Port Totally Laparoscopic Distal Gastrectomy With D2 Lymph Node Dissection
The purpose of this study is to determine if reduced port totally laparoscopic distal gastrectomy with complete D2 lymph node dissection for gastric cancer is safe and oncological feasible.
- Trial name
- NCT02311595
- Testing
- reduced port laparoscopic distal gastrectomy
- Volunteers
- 67 people
- Sponsor
- Samsung Medical Center
Adenocarcinoma of the Stomach
Early Oral Feeding After Total Gastrectomy for Cancer
The aim of this study is to evaluate the possibility of shortening postoperative hospital stay after gastrectomy by early oral feeding as a component of an enhanced recovery protocol (ERAS).
- Trial name
- NCT01962519
- Testing
- Early oral feeding
- Where
- Poland
- Volunteers
- 112 people
- Sponsor
- Jagiellonian University
Gastric Cancer, Splenic Hilum Lymph Nodes Dissection
Laparoscopic-assisted Total Gastrectomy Versus Open Total Gastrectomy With Splenic Hilum Lymph Nodes Dissection
This study investigates the safety and feasibility of laparoscopic-assisted total gastrectomy with spleen-preserving splenic hilum lymph node dissection for proximal advanced gastric cancer and compares the early results of this…
- Conditions
- Gastric Cancer, Splenic Hilum Lymph Nodes Dissection, Total Gastrectomy
- Trial name
- NCT02711033
- Testing
- Laparoscopic-assisted total gastrectomy, Open total gastrectomy
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Gastric Cancer, Robotic Gastrectomy
Total Robotic Versus Robotic Assisted Distal Gastrectomy for Gastric Cancer
To evaluate the clinical efficacy (safety, feasibility and long-term efficacy) of total robotic versus robotic assisted distal gastrectomy for patients with gastric cancer (cT1-4a, N0/+, M0).
- Trial name
- NCT04795063
- Testing
- Total Robotic Distal Gastrectomy, Robotic-Assisted Distal Gastrectomy
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Fujian Medical University
Gastric Cancer
Impact of Roux-En-Y Pouch Reconstruction Compared With Conventional Roux-En-Y Reconstruction on Health-Related Quality of Life in Patients Undergoing Total Gastrectomy for Adenocarcinoma
This study is being done to learn more about how different surgery procedures bring back the eating pathway after removing the stomach in patients with stomach cancer.
- Trial name
- NCT01491698
- Testing
- Roux-en-Y pouch reconstruction (RYP), conventional Roux-en-Y reconstruction (RYC)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Foreign Body Left During Endoscopic Examination
Efficacy Study of a Low Volume of Water Intake and Mosapride for Endoscopy in Patients With Subtotal Gastrectomy
A low volume of water intake and mosapride will effectively reduce food residue in remnant stomach for patients who had undergone subtotal gastrectomy due to gastric cancer.
- Trial name
- SMW (NCT01284764)
- Testing
- Mosapride
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Inje University
Early Gastric Cancer
Short-term Outcomes of Laparoscopic Versus Open Gastrectomy With Lymph Node Dissection for Early Gastric Cancer :a Randomized Controlled Study
While the incidence of gastric cancer is gradually declining, it is the fifth most common cancer worldwide and the third most common cause of cancer related death worldwide according to GLOBOCAN 2018 data (Rawla P and Barsouk…
- Trial name
- NCT05707338
- Testing
- Gastrectomy with lymph node dissection
- Volunteers
- 40 people
- Sponsor
- Sohag University
Stomach Neoplasms
Maxigesic for Postoperative Pain Control After Laparoscopic or Robotic Gastrectomy
This prospective, randomized, phase 4 clinical trial aims to evaluate the efficacy and safety of intravenous Maxigesic, a fixed-dose combination of acetaminophen and ibuprofen, for postoperative pain control in patients…
- Trial name
- NCT07768514
- Testing
- Acetaminophen and Ibuprofen, Acetaminophen
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Bundang Hospital
Stomach Neoplasms
Laparoscopic Proximal Gastrectomy With Double-flap Technique Versus Laparoscopic Total Gastrectomy With Roux-en-Y Reconstruction for Proximal Early Gastric Cancer
Proximal early gastric cancer can choose radical total gastrectomy or proximal gastrectomy. But if use simple esophagogastric anastomosis for proximal gastrectomy, the incidence of postoperative reflux esophagitis is up to 62%…
- Trial name
- NCT05890339
- Testing
- Laparoscopic Proximal Gastrectomy With Double-flap Technique, Laparoscopic Total Gastrectomy With Roux-en-Y Reconstruction
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Gastric Cancer
Safety and Efficacy of OGT Method Versus the Traditional Overlap Method
Introduction: The safety and efficiency of OGT-assisted method have not yet been compared with conventional overlap approach. Methods Retrospectively analyses the data of 155 gastric/gastroesophageal junction (G/GEJ) cancer…
- Trial name
- OGT (NCT05442502)
- Testing
- The overlap guiding tube(OGT) method, The conventional overlap method
- Where
- China
- Volunteers
- 155 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Gastric Cancer
Robotic and Laparoscopic Total Gastrectomy With D2 Lymphadenectomy for Locally Advanced Gastric Cancer
This study is a prospective, single-center, non-randomized, controlled, non-blind, and non-inferiority observation trial comparing robotic-assisted total gastrectomy with D2 lymph nodal dissection for locally advanced gastric…
- Trial name
- NCT03500471
- Testing
- Robotic-assisted Total Gastrectomy, Laparoscopic-assisted Total Gastrectomy
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Southwest Hospital, China
Total Laparoscopic Distal Gastrectomy, Locally Advanced Gastric Cancer
Comparison of Short Term Outcomes Between Totally Laparoscopic and Laparoscopy-Assisted Distal Gastrectomy With Billroth-II Reconstruction and D2 Lymphadenectomy for Locally Advanced Gastric Cancer
Prospective Randomized Controlled Multicenter Clinical Trial for Comparison of Safety Between Totally Laparoscopic Distal Gastrectomy(TLDG) and Laparoscopy-Assisted Distal Gastrectomy(LADG) With Billroth-II Reconstruction and D2…
- Trial name
- NCT02365896
- Testing
- TLDG or LADG
- Volunteers
- 176 people
- Sponsor
- Fujian Cancer Hospital
Gastric Cancer
Clinical Study for the Impact of Bio-absorbable Felt (NEOVEIL®) With Fibrin Sealant on Removal of Drainage Tube After Minimally Invasive Gastrectomy for Gastric Cancer
This study is to evaluate if Bio-absorbable Felt(NEOVEIL®) makes the amount of exudate reduce and shortens time until drain removal after minimally invasive surgery for early gastric cancer.
- Trial name
- NCT01742806
- Testing
- bio-absorbable felt(NEOVEIL®)
- Where
- 7 sites in South Korea
- Volunteers
- 120 people
- Sponsor
- Yonsei University
Gastric Cancer
RCT Comparing Reduced-port Robotic and Conventional Laparoscopic Subtotal Gastrectomy
"Study objective The objective of this study is to evaluate whether reduced-port robotic subtotal gastrectomy demonstrates non-inferiority in safety, specifically regarding the incidence of postoperative complications, compared…
- Trial name
- REPROG-RCT (NCT07467174)
- Testing
- conventional laparoscopy gastrectomy group (Port > 3), reduced-port robotic group (Port ≤ 3)
- Where
- South Korea
- Volunteers
- 538 people
- Sponsor
- Yonsei University
Gastric Cancer
Validation of a Model for Predicting Anastomotic Leakage
This study will validate a machine learning model for predicting anastomotic leakage of esophagogastrostomy and esophagojejunostomy.
- Trial name
- NCT05646290
- Where
- China
- Volunteers
- 512 people
- Sponsor
- Jichao Qin
Gastric Cancer (GC), Siewert Type III Adenocarcinoma of Esophagogastric Junction
Immediate and Functional Results of Different Types of Reconstructions After Proximal Gastrectomy For Gastric and Esophagogastric Junction Cancer
Proximal gastric and esophagogastric junction cancers comprise up to 40% of gastric malignancies. For localized disease, proximal gastrectomy is the main radical procedure, but reconstruction of GI tract often leads to…
- Conditions
- Gastric Cancer (GC), Siewert Type III Adenocarcinoma of Esophagogastric Junction, Siewert Type II Adenocarcinoma of Esophagogastric Junction
- Trial name
- PROXISTAT (NCT07441785)
- Testing
- Proximal Gastrectomy
- Where
- Russia
- Volunteers
- 400 people
- Sponsor
- P. Herzen Moscow Oncology Research Institute
Stomach Cancer
Nab-paclitaxel Combined With S-1 as Adjuvant Chemotherapy for Stage Ⅲ Gastric Cancer
This is a randomized, open-label phase III study. The treatment was compare the efficacy and safety of Albumin-bound Paclitaxel plus S-1 versus Oxaliplatin plus capecitabine (XELOX) treating stage Ⅲ gastric cancer as adjuvant…
- Trial name
- NCT04135781
- Testing
- nab paclitaxel, Tegafur, Oxaliplatin
- Where
- China
- Volunteers
- 616 people
- Sponsor
- Zhejiang Cancer Hospital
Stomach Neoplasms, Esophagogastric Junction Disorder
Perioperative Chemoimmunotherapy With/Without Preoperative Chemoradiation for Locally Advanced Gastric Cancer
NeoRacing is a randomized phase II trial carried out at Fudan University Shanghai Cancer Center (FUSCC) in China. The study can be divided into the screening stage, treatment stage and follow-up stage.
- Conditions
- Stomach Neoplasms, Esophagogastric Junction Disorder, Neoadjuvant Therapy, Chemoradiotherapy
- Trial name
- NeoRacing (NCT05161572)
- Testing
- Oxaliplatin, Tegafur-Gimeracil-Oteracil, Sintilimab
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Fudan University
Gastric Cancer
Laparoscopic Versus Open Gastrectomy for Gastric Cancer
This is the first randomized controlled trial comparing laparoscopic and open gastrectomy for resectable gastric cancer in a Western population.
- Trial name
- LOGICA (NCT02248519)
- Testing
- Open Gastrectomy, Laparoscopic Gastrectomy
- Where
- 10 sites in Netherlands
- Volunteers
- 210 people
- Sponsor
- UMC Utrecht
Gastric (Cardia, Body) Cancer
Quality of Life After Billroth II or Roux-en-Y for Gastric Cancer
The treatment of a local distal gastric cancer remains surgical before or after chemotherapy. Partial gastrectomy is recommended for distal location cancer The recommendations for restoring continuity are less evident.
- Trial name
- BYQoL-GC (NCT06768164)
- Testing
- Billroth 2 (B2), Roux-En-Y (REY)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris