Clinical trials: Gastric
Autoimmune Gastritis
Exploratory Study on the Efficacy of Betaine Hydrochloride in Treating Autoimmune Gastritis
Autoimmune gastritis (AIG) is a chronic autoimmune disorder characterized by parietal cell destruction and oxyntic mucosal atrophy, leading to achlorhydria and intrinsic factor deficiency.
- Trial name
- NCT06881511
- Testing
- No intervention (Control Group), Oral betaine hydrochloride (2 capsules, 3 times daily)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Gastric Cancer, Gastroesophageal-junction Cancer
TCRx_T Cells for Advanced or Recurrent Gastric/Gastroesophageal Junction Cancer After Failure of First Chemotherapy
To observe and determine the safety, tolerability, cellular pharmacokinetics and efficacy of TCRx T cells in patients with advanced or recurrent gastric/gastroesophageal junction cancer after failure of first chemotherapy.
- Trial name
- NCT05447234
- Testing
- Tcrx T cell
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Tumor Gastric, Tumor, Colorectal
TSA-DC Vaccine in Treating Patients With Gastrointestinal Solid Tumor
The goal of this study is to learn about the safety and tolerance of autologous TSA-DC cell and evaluate the efficacy and feasibility of the cell therapy compared to the patients' past standard regimen.
- Trial name
- NCT03185429
- Testing
- Tumor Specific Antigen-loaded Dendritic Cells, Cyclophosphamide
- Volunteers
- 20 people
- Sponsor
- BGI, China
Stomach Cancer, Colorectal Cancer
Trial of Cytoreductive Surgery and HIPEC in Patients With Primary and Secondary Peritoneal Cancers
Patients with primary peritoneal cancer or secondary peritoneal cancers from stomach, colorectal, appendiceal, and gynecological primary origin will be screened by pathology and staging to see if they are eligible to undergo…
- Conditions
- Stomach Cancer, Colorectal Cancer, Appendiceal Cancer, Ovarian Cancer
- Trial name
- NCT03604653
- Testing
- HIPEC, Mitomycin c, CDDP 50
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Holy Name Medical Center, Inc.
Stomach Neoplasms, Esophagogastric Junction Disorder
Perioperative Chemoimmunotherapy With/Without Preoperative Chemoradiation for Locally Advanced Gastric Cancer
NeoRacing is a randomized phase II trial carried out at Fudan University Shanghai Cancer Center (FUSCC) in China. The study can be divided into the screening stage, treatment stage and follow-up stage.
- Conditions
- Stomach Neoplasms, Esophagogastric Junction Disorder, Neoadjuvant Therapy, Chemoradiotherapy
- Trial name
- NeoRacing (NCT05161572)
- Testing
- Oxaliplatin, Tegafur-Gimeracil-Oteracil, Sintilimab
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Fudan University
Surgical Site Infections, Gastric Cancer
Povidone-iodine and the Normal Saline Cleaning the Incision for the SSIs
Surgical site infections (SSIs) is one of the most common complications of upper abdominal surgery. Previous studies found that type of surgical incision, emergency operation or not, surgical duration, age of patient, body mass…
- Conditions
- Surgical Site Infections, Gastric Cancer, Dehiscence of Laparotomy Wound
- Trial name
- NCT02436395
- Testing
- Group A (povidone-iodine wash the surgical incision), Group B (normal saline wash the surgical incision)
- Where
- China
- Volunteers
- 340 people
- Sponsor
- West China Hospital
Gastric Cancer
Study of S1 Efficacy and Toxicity as Second-line Treatment on Inoperable or Advanced Gastric Cancers
The primary purpose of the study is to investigate the correlation between the efficacy and toxicity of S-1 on gastric cancers and the expression of thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD) and orotate…
- Trial name
- NCT01650766
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Affiliated Hospital of the Chinese Academy of Military Medical Sciences
Stomach Neoplasms, Colonic Neoplasms
Efficacy and Safety of a Preoperative Aerobic Exercise Program in Patients With Gastrointestinal Cancer.
Patients with gastrointestinal cancer often experience physical deconditioning; this could lead to an increased risk of complications, especially when they require major abdominal surgical procedures.
- Conditions
- Stomach Neoplasms, Colonic Neoplasms, Rectal Neoplasms, Liver Neoplasm
- Trial name
- NCT03423056
- Testing
- Preoperative exercise program
- Where
- Colombia
- Volunteers
- 40 people
- Sponsor
- Instituto Nacional de Cancerologia, Columbia
Functional Dyspepsia, Gastroparesis
Brain-Gut Yoga for Functional Dyspepsia and Gastroparesis (FD-GP)
The purpose of this research study is to assess whether using a yoga-based intervention in practice is feasible (possible) and acceptable to patients with Functional Dyspepsia and/or Gastroparesis (FD-GP).
- Trial name
- FD-GP (NCT06732453)
- Testing
- Seated Yoga Skills Training in Functional Dyspepsia and Gastroparesis (FD-GP)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
GERD
Surgery in Chronic Cough GERD Related
The effectiveness of surgical fundoplication in treating classical reflux symptoms is well documented, but the role of surgery in alleviating extra-esophageal symptoms allegedly secondary to gastro-esophageal reflux disease…
- Trial name
- CCGERD (NCT01899183)
- Testing
- Anti-reflux Surgery
- Where
- Italy
- Volunteers
- 67 people
- Sponsor
- University of Bologna
Gastric Cancer, Prehabilitation
Whole Course Multi-model Prehabilitation to Improve Clinical Outcome in Patients Undergoing Neoadjuvant Treatment Prior to Gastrectomy
The intention of research is to establish a multimodal prehabilitation protocol in patients who undergo neoadjuvant chemotherapy prior to gastrectomy, explore the feasibility and effectiveness of the measures and evaluate the…
- Trial name
- NCT06521541
- Testing
- Multimodal prehabilitation program, ERAS program
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Gastric Cancer
Olanzapine Improves the Chemotherapy Tolerance of Advanced Gastric Cancer
To explore whether adding olanzapine to paclitaxel chemotherapy could improve chemotherapy tolerance and improve patient quality of life and prolong treatment failure time (TTF) in advanced gastric cancer after failure of…
- Trial name
- NCT03575637
- Testing
- Olanzapine
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Peking University
Advanced Gastric and Gastro-oesophageal Junction Adenocarcinoma
A Study of Anlotinib Hydrochloride Capsule Combined With AK105 Injection in Subject With Advanced Gastric and Gastro-oesophageal Junction Adenocarcinoma
This is a randomized, controlled, open-label, multicenter study to evaluate efficacy of AK105 injection combined with Anlotinib Hydrochloride Capsules versus standard second-line chemotherapy.
- Trial name
- NCT04385550
- Testing
- Anlotinib hydrochloride capsule, AK105 injection, Paclitaxel injection
- Where
- 45 sites in China
- Volunteers
- 528 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Chronic Atrophic Gastritis
Treatment of Atrophic Gastritis After HP Eradication With Modified Liujunzi Decoction Based on Syndrome Differentiation
This is an observational cohort study of clinical efficacy study.The purpose of this topic is to evaluate the efficacy and safety of Modified Liujunzi Decoction based on syndrome differentiation in patients with chronic atrophic…
- Trial name
- NCT05388890
- Testing
- MLD, WFC
- Where
- China
- Volunteers
- 286 people
- Sponsor
- Peking University First Hospital
Early Gastric Cancer or Gastric Adenoma
Full-time RDI for ESD: Impact on Major Adverse Events and Procedure Time
Gastric cancer remains a major global health burden, ranking fifth in incidence worldwide and disproportionately affecting Asia, with China accounting for a significant share of cases and deaths.
- Trial name
- NCT07401303
- Testing
- ESD
- Where
- China
- Volunteers
- 640 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Digestive Physiology, Gastrointestinal Motility
Effects of Exendin(9-39) on Gastroduodenal Motility
The purpose of this study in humans is to define the effects of the endogenous hormone GLP-1 on gastroduodenal motility and on endocrine pancreatic secretion by using the specific GLP-1 receptor antagonist exendin(9-39).
- Conditions
- Digestive Physiology, Gastrointestinal Motility, Gastrointestinal Hormones, Glucagon-like Peptide 1
- Trial name
- NCT00468091
- Testing
- exendin(9-39)amide, atropine
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Vagotomy, Truncal
Intact Vagal Innervation and Glucagon-like Peptide-1 (GLP-1) Effects
The aim of this study is to investigate the role of transmission via the vagal nerve for the effect of Glucagon-like peptide-1 (GLP-1) in respect to gastric emptying, appetite and food intake.
- Trial name
- NCT01176890
- Testing
- GLP-1, Saline
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Solid Tumor, KRAS Mutation
A Study to Test How Well Different Doses of BI 3706674 Are Tolerated by People With Advanced Cancer in the Stomach and Oesophagus
This study is no longer open to new participants. It was a study in adults with advanced cancer in the stomach and oesophagus. This is a study for people for whom previous treatment was not successful or no treatment exists.
- Trial name
- NCT06056024
- Testing
- BI 3706674
- Where
- 17 sites in United States, Japan and 2 more
- Volunteers
- 47 people
- Sponsor
- Boehringer Ingelheim
Diagnostic Gastric Endoscopy
Comparison of Remimazolam and Propofol Effect on Oxygenation Reservoir During Diagnostic Gastric Endoscopy
Propofol is one of the most commonly used sedative in endoscopic procedures, while its potency to induce respiratory depression may threaten patient safety.
- Trial name
- NCT05723627
- Testing
- Remimazolam besylate, Propofol
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yonsei University