Clinical trials: Gastric (Stomach) Cancer
Aspirin, Gastric Cancer
Aspirin Use for Gastric Cancer Prevention in the Early Gastric Cancer Patients
This study aimed to investigate the effect of low-dose (100 mg) asprin on the prevention of gastric cancer in the early gastric cancer patients with negative H. pylori status who underwent endoscopic submucosal dissection.
- Trial name
- EASTERN (NCT04214990)
- Testing
- Aspirin 100mg
- Where
- 10 sites in South Korea
- Volunteers
- 1,700 people
- Sponsor
- National Cancer Center, Korea
Stomach (Gastric) Cancer
Antineoplaston Therapy in Treating Patients With Stomach Cancer
Current therapies for Stomach Cancer provide very limited benefit to the patient. The anti-cancer properties of Antineoplaston therapy suggest that it may prove beneficial in the treatment of Stomach Cancer.
- Trial name
- NCT00003524
- Testing
- Antineoplaston therapy (Atengenal + Astugenal)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Burzynski Research Institute
Gastric Cancer, Immunonutrition
Oral Supplementation of Glutamine on Gastric Cancer Patients After Gastrectomy
Glutamine has the potentials of immunomodulation and adjustment of protein metabolism. The primary objective of this study is to evaluate the efficacy of glutamine on sarcopenia in gastric adenocarcinoma patients undergoing…
- Conditions
- Gastric Cancer, Immunonutrition, Gastrostomy
- Trial name
- NCT06027242
- Testing
- oral glutamine, Maltodextrin
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Pancreatic Cancer, Gastric Cancer
Combined Exercise and Nutritional Intervention in GI Cancer Patients
Although some studies have focused on the role of exercise on inflammation and cytokine expression in cancer patients undergoing treatment and survivors, to our knowledge none have investigated the effect of exercise during…
- Conditions
- Pancreatic Cancer, Gastric Cancer, Diet, Exercise
- Trial name
- NCT05420259
- Testing
- Combined Exercise and Dietary Intervention (CEDI), Standard Care
- Where
- 2 sites in Portugal
- Volunteers
- 68 people
- Sponsor
- Hospital Beatriz Ângelo
Gastric Cancer, Colorectal Cancer
A Phase 1 Study of SHR-A1811 in Patients With Selected HER2 Expressing Tumors
This is a single arm, open-label, dose escalation, PK expansion and efficacy expansion study of phase I. The purpose of this study is to assess the tolerability, safety, pharmacokinetics and immunogenicity of SHR-A1811 and…
- Trial name
- NCT04513223
- Testing
- SHR-A1811
- Where
- China
- Volunteers
- 101 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Gastric Cancer, Chemotherapy Effect
Neoadjuvant Chemotherapy Plus Surgery Versus Surgery First For Elderly Gastric Cancer Patients
The main purpose of this study is to compare the feasibility and efficacy of neoadjuvant chemotherapy (modified SOX) for elderly patients with locally advanced gastric cancer.
- Conditions
- Gastric Cancer, Chemotherapy Effect, Elderly Patients, Surgery
- Trial name
- RJGC-Senile (NCT04677673)
- Testing
- Chemotherapy, Curative gastrectomy
- Volunteers
- 232 people
- Sponsor
- BIRENDRA KUMAR SAH
Anemia
Ferinject® Assessment In GastRectomy Patients With Acute Isovolemic Anemia (FAIRY)
This study is designed to evaluate the efficacy of Ferinject® in improving acute isovolemic anemia after gastrectomy for gastric cancer in terms of Quality of life(QOL )and objective measures (Hb and iron parameters).
- Trial name
- NCT01725789
- Testing
- Ferinject®, normal saline
- Where
- 6 sites in South Korea
- Volunteers
- 454 people
- Sponsor
- National Cancer Center, Korea
Gastric Cancer
Efficacy of RUS GA Surgical Navigation for Robot-assisted Distal Gastrectomy in Gastric Cancer Patients
This investigator-initiated, randomized superiority clinical trial aims to demonstrate the clinical effectiveness of RUS GA Surgical Navigation, an endoscopic imaging treatment planning software, in patients undergoing…
- Trial name
- NCT06639490
- Testing
- RUS GA, standard treatment
- Where
- South Korea
- Volunteers
- 330 people
- Sponsor
- Yonsei University
Gastric / Gastroesophageal Junction Adenocarcinoma
Phase 3 Study of Cadonilimab Combined With Chemotherapy vs Chemotherapy in Combination With or Without Nivolumab for the 1L Treatment of Participants With HER2-negative, Previously Untreated, Unresectable or Metastatic Gastric/GEJ Adenocarcinoma
The goal of this randomized, double-blind, multi-regional phase 3 study of cadonilimab combined with chemotherapy versus chemotherapy in combination with or without nivolumab for the first-line treatment of participants with…
- Trial name
- G/GEJ (NCT07700979)
- Testing
- Cadonilimab, CAPOX regimen, Nivolumab
- Where
- 25 sites in United States, China and 2 more
- Volunteers
- 900 people
- Sponsor
- Akeso
Peritoneal Metastases From Gastric Cancer
HIPEC and Systemic Chemotherapy Combined With Apatinib in Unresectable Peritoneal Metastases From Gastric Cancer
The prognosis of patients with unresectable peritoneal metastases from gastric cancer is poor. These patients may obtain survival benefit from radical gastrectomy and cytoreductive surgery (CRS).
- Trial name
- NCT03349827
- Testing
- exploratory laparoscopy or laparotomy, HIPEC, Systemic chemotherapy
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Wuhan University
Anal Cancer, Carcinoma of the Appendix
Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer
RATIONALE: Drugs used in chemotherapy, such as irinotecan, fluorouracil, and leucovorin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Anal Cancer, Carcinoma of the Appendix, Colorectal Cancer, Esophageal Cancer
- Trial name
- NCT00654160
- Testing
- fluorouracil, irinotecan hydrochloride, leucovorin calcium
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Mayo Clinic
Lung Cancer, Colorectal Cancer
A Clinical Research of CAR T Cells Targeting CEA Positive Cancer
The main purpose of this research is to verify the safety of CEA targeted chimeric antigen receptor T cells and to determine the proper dosage of CAR T cells infused.
- Conditions
- Lung Cancer, Colorectal Cancer, Gastric Cancer, Breast Cancer
- Trial name
- NCT02349724
- Testing
- Anti-CEA-CAR T
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Southwest Hospital, China
Gastric Cancer, Surgery
Clinical Efficacy of Adebrelimab With or Without Apatinib Mesilate and SOX Neoadjuvant Therapy in Locally Advanced Gastric Cancer
Exploring the pathological complete response rate (pCR) of locally advanced gastric cancer treated with adebelimab combined or not combined with apatinib mesylate and SOX neoadjuvant therapy
- Trial name
- SOP-XH-IRB (NCT07314203)
- Testing
- Apatinib Mesylate Tablets
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Fujian Medical University
Gastric Adenoma, Early Gastric Cancer
The Effect of Proton Pump Inhibitor and Polaprezinc Combination Therapy for Healing of Endoscopic Submucosal Dissection-induced Ulcer
Endoscopic submucosal dissection (ESD) is an advanced technique that enables en bloc resection of superficial tumors in the gastrointestinal tract.
- Trial name
- NCT02243618
- Testing
- Polaprezinc, Rebamipide
- Where
- South Korea
- Volunteers
- 153 people
- Sponsor
- Yonsei University
GI Cancer
Effect of Geriatric Intervention in Frail Patients with Gastric, Biliary, and Pancreatic Cancer Receiving Palliative Chemotherapy
Gastric, biliary and pancreatic cancer are commonly malignancies from gastro- intestinal tract in Taiwan. Because lack of specific symptoms at presentation and effective screening methodology, majority of these patients are…
- Trial name
- NCT06040801
- Testing
- Frailty intervention measures
- Where
- Taiwan
- Volunteers
- 138 people
- Sponsor
- Chang Gung Memorial Hospital
Stomach Neoplasms, Peritoneal Metastases
HIPEC-AS in Patients With Peritoneal Metastasis of the Stomach or Esophagogastric Junction
HIPEC-AS01 is an open, prospective, single-center phase II clinical study, which will include "cT4aNxM0, P0 or cTxNxM1, P1" patients with gastric or esophagogastric junction adenocarcinoma, to evaluate the efficacy and safety of…
- Trial name
- NCT05095467
- Testing
- HIPEC, Paclitaxel-albumin, Tegafur-gimeracil-oteracil potassium
- Volunteers
- 157 people
- Sponsor
- Xuefei.Wang
Colorectal Neoplasms, Gastric Neoplasms
Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer
Background: Recent advances in cancer research have led to new therapies to treat the disease. It is important to continue these advances and discover new ones. To do that, researchers need tissue samples from solid tumors.
- Conditions
- Colorectal Neoplasms, Gastric Neoplasms, Cholangiocarcinoma, Bile Duct Cancer
- Trial name
- NCT01915225
- Where
- United States
- Volunteers
- 1,800 people
- Sponsor
- National Cancer Institute (NCI)
Cancer
Multiple Ascending Dose of BMS-911543
The purpose of this first in human study is to determine if BMS-911543 is safe and tolerable in subjects with symptomatic intermediate-1, intermediate-2 or high risk myelofibrosis to permit clinical testing at the Maximum…
- Trial name
- NCT01236352
- Testing
- BMS-911543
- Where
- 5 sites in United States, Australia
- Volunteers
- 98 people
- Sponsor
- Bristol-Myers Squibb
Breast Cancer, Gastric Cancer (GC)
PET Image Exploration of 89Zr-labeled Antibody Fragments Targeting HER2 in Patients With Malignant Tumors
The purpose of this study is to develop and clinically evaluate 89Zr-labeled HER2-targeted antibody fragments in diagnosis and screening of HER2-positive cancer patients.
- Conditions
- Breast Cancer, Gastric Cancer (GC), Urothelial Carcinoma (UC)
- Trial name
- NCT07023848
- Testing
- 89Zr-LNCab104, 89Zr-LNCab103, 18F-FDG
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Affiliated Hospital of Jiangnan University
Metastatic Gastric Cancer
Clinical Study of VG161 Combined With Nivolumab Injection in Patients With Advanced Metastatic Gastric Cancer
VG161 is a recombinant human-IL12/15/PDL1B oncolytic HSV-1 injection. This study will be conducted in combination with nivolumab injection in HSV seropositive subjects with advanced metastatic gastric or gastroesophageal junction…
- Trial name
- NCT06008925
- Testing
- Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection (Vero Cell)), Nivolumab Injection
- Where
- China
- Volunteers
- 43 people
- Sponsor
- CNBG-Virogin Biotech (Shanghai) Ltd.
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