Clinical trials: Gastric (Stomach) Cancer
Gastric Neoplasm, Gastric Lesion
Single-center, Randomized, Superiority Pivotal Clinical Study to Evaluate the Efficacy of Artificial Intelligence-based Upper Gastrointestinal Endoscopy Image
We will conduct a single-center retrospective study at a university hospital. A total of 3,385 gastroscopic white-light images from patients with pathologically confirmed findings will be analyzed.
- Conditions
- Gastric Neoplasm, Gastric Lesion, Artificial Intelligence
- Trial name
- NCT06969794
- Where
- South Korea
- Volunteers
- 3,385 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Frailty
Effects of Preoperative Frailty on Postoperative Recovery
This study aims to evaluate frailty using Short Physical Performance Battery (SPPB) before surgery and find out how frailty affects short-term postoperative recovery after surgery using Quality of Recovery-15 (QOR-15)…
- Trial name
- NCT06185270
- Testing
- SPPB
- Volunteers
- 139 people
- Sponsor
- Seoul National University Hospital
Advanced Gastric Cancer
Clinical Trial on the Safety, Tolerance and Preliminary Efficacy of XH001 Injection Combined With Neoantigen Vaccine-induced Tumor-specific T-cell Injection in Advanced Gastric Cancer
The goal of this clinical trial is to learn the safety of tumor neoantigen vaccine combined with neoantigen vaccine induced T-cell in treating advanced gastric cancer in adults.
- Trial name
- NCT07298200
- Testing
- XH001 Injection, Tumor vaccine-induced specific T-cell injection
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Jia Wei
Gastric Cancer
Phase I/II Study of Paclitaxel Plus CPT-11 in Pts. With 2nd Line Chemotherapy of Inoperable or Recurrent GC.
A phase I/II study is conducted to determine the maximum-tolerated dose (MTD), dose-limiting toxicity (DLT), and efficacy of a combination chemotherapy using CPT-11 and Paclitaxel in pre-treated patients with metastatic gastric…
- Trial name
- NCT00209612
- Testing
- Taxol, Campt, Topotesin
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- Hokkaido Gastrointestinal Cancer Study Group
HER2-Expressing Solid Tumors
Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of MT-304 in Adults With Advanced HER2-Expressing Solid Tumors
This clinical trial is designed to evaluate the safety, pharmacokinetics, pharmacodynamics, and preliminary efficacy of MT-304 in adults with advanced HER2-expressing solid tumors.
- Trial name
- NCT07334119
- Testing
- MT-304, MT-304 + Nivolumab
- Where
- 7 sites in Australia
- Volunteers
- 60 people
- Sponsor
- Myeloid Therapeutics
Total Gastrectomy, Gastric Cancer
Reconstruction With a Lawrence-Hunt Jejunal Pouch After Total Gastrectomy
The aim of the study is to establish the efficacy of jejunal pouch reconstruction in reducing dumping syndrome in patients undergoing total gastrectomy, ultimately enhancing postoperative quality of life and nutritional status.
- Trial name
- REJOY (NCT06967571)
- Testing
- Jejunal Pouch reconstruction.
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Esophageal Cancer, Kidney Cancer
GI Organ Tracking Via Balloon Applicators
The hypothesis of this study is that an occlusion balloon catheter placed in the stomach via an oral or nasogastric route will be safe and permit tracking of the stomach during radiation therapy.
- Conditions
- Esophageal Cancer, Kidney Cancer, Larynx Cancer, Liver Cancer
- Trial name
- NCT05471401
- Testing
- Balloon-tipped catheter
- Sponsor
- Washington University School of Medicine
Gastric Cancer
The Safety and Efficacy of PD-1 Monoantrapical Chemotherapy in the Treatment of Local Advanced Stomach Cancer
To explore the safety and efficacy of local advanced stomach cancer patients receiving new complementary treatment of PD-1 monoantiotherapy before surgery
- Trial name
- NCT05000554
- Testing
- Neoadjuvant Therapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Hospital of Jilin University
Gastric Cancer
The Safety and Feasibility of Reduced Port Robotic Distal Gastrectomy Using Single-site for Surgical Treatment of Early Gastric Cancer
Gastric cancer is one of the most common malignancy worldwide. Surgical resection of the tumor is the only curative treatment for gastric cancer.
- Trial name
- NCT02347956
- Testing
- Reduced port robotic distal gastrectomy
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- Yonsei University
Solid Tumor, Gastric Cancer
Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors
This study was planned as an open-label, multi-site, Phase I/IIa dose escalation, safety, and pharmacokinetic (PK) trial of BNT141 followed by expansion cohorts in patients with Claudin 18.2 (CLDN18.2)-positive tumors.
- Conditions
- Solid Tumor, Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Esophageal Adenocarcinoma
- Trial name
- NCT04683939
- Testing
- BNT141, Nab-paclitaxel, Gemcitabine
- Where
- 7 sites in United States, Canada
- Volunteers
- 13 people
- Sponsor
- BioNTech SE
Gastric Cancers, Colorectal Cancer
Predictive Effect of Abdominal Fat and Muscle Area Calculated Based on Abdominal CT on Gastric Cancer Patients
This study aims to create a clinical prediction model. Abdominal fat and muscle area also play an important role in the prediction of surgical outcomes in colorectal cancer.
- Conditions
- Gastric Cancers, Colorectal Cancer, Sarcopenia, Obesity and Overweight
- Trial name
- NCT06606912
- Testing
- Skeletal muscle, subcutaneous fat and visceral fat area
- Where
- 3 sites in China
- Volunteers
- 4,000 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Lung Cancer, Gastro-intestinal Cancer
The SOAR Study: a Study of Geriatric Assessment and Exercise for Older Adults and Their Support Person
Phase 2 randomized controlled study using a waitlist control group. The study also has a single arm pre-post test 12-week chair-based exercise arm for those who have received the geriatric assessment in the older adults with…
- Conditions
- Lung Cancer, Gastro-intestinal Cancer, Genito-Urinary Cancer, Breast Cancer
- Trial name
- SOAR (NCT05509751)
- Testing
- GAM, exercise, health education, online chair-based exercise combined with health education
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Martine Puts
Stomach Cancer, Colon Cancer
A Study With Health Educational Material on Health Promotion in Cancer Survivors
The purpose of this study is to provide educational material to promote screening for second primary cancer for the intervention group, or educational material to instruct appropriate use of dietary supplement for the control…
- Conditions
- Stomach Cancer, Colon Cancer, Thyroid Cancer, Breast Cancer
- Trial name
- NCT00948337
- Testing
- Brochure of Secondary Cancer Screening
- Where
- 2 sites in South Korea
- Volunteers
- 326 people
- Sponsor
- National Cancer Center, Korea
Gastric Cancer
Neoadjuvant Chomotherapy With Paclitaxel-albumin and S-1 for Advanced Gastric Cancer
This is a interventional clinical trial to assess the efficacy and safety of combinational therapy of paclitaxel-albumin and S-1 for the neoadjuvant chemotherapy of advanced gastric cancer.
- Trial name
- NCT04258657
- Testing
- paclitaxel-albumin and S-1
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Friendship Hospital
Squamous Cell Lung Cancer, Gastric Cancer
Phase Ib Study of Oral R01 Monotherapy in Advanced Solid Tumors
This is a Phase I（Ib）, open-label, single-arm clinical study designed to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of R01 administered orally as monotherapy twice daily (BID) in patients…
- Conditions
- Squamous Cell Lung Cancer, Gastric Cancer, Esophageal Cancer
- Trial name
- NCT07806500
- Testing
- R01
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Beijing Anjianxi Bio-Medical Technology Co., Ltd.
Esophageal Cancer, Gastric Cancer
Matuzumab Treatment With Epirubicin, Cisplatin and Capecitabine (ECX) in Esophago-Gastric Cancer
The purpose of this study is to compare the effectiveness and safety of experimental treatment matuzumab and ECX chemotherapy, with ECX chemotherapy.
- Trial name
- MATRIX EG (NCT00215644)
- Testing
- Matuzumab, Epirubicin, Cisplatin
- Where
- 22 sites in Germany, Spain and 2 more
- Volunteers
- 72 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Gastric Adenocarcinoma, Gastric Cancer
Effects of the Use of Probiotics on the Intestinal Microbiota of Patients With Gastric Cancer
The objective of this randomized controlled, prospective clinical study, composed of 5 groups, G1, G2, G3, G4 and G5 is [Evaluate the intestinal microbiota profile, nutritional, immunological status and inflammatory profile…
- Conditions
- Gastric Adenocarcinoma, Gastric Cancer, Microbiome, Cytokines
- Trial name
- PRONIC-G (NCT06250075)
- Testing
- Formulation with probiotics, Non-intervention for Clinical Outcomes -G5
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- Universidade Federal do Amazonas
Cachexia, Oesophageal Cancer
REVOLUTION Surgery (REVOLUTION Surgery)
Some people with cancer suffer from muscle wasting, lose weight and feel tired. This process, termed cachexia, is a significant problem and can lead to a reduction in both quality and quantity of life.
- Conditions
- Cachexia, Oesophageal Cancer, Gastric Cancer, Pancreatic Cancer
- Trial name
- NCT05642819
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Edinburgh
Hepatocellular Carcinoma, Gastric Cancer
Combination of TATE and PD-1 Inhibitor in Liver Cancer
This is a multi-center, open-label phase IIA study that investigates the preliminary efficacy of Trans-arterial Tirapazamine Embolization (TATE) treatment of liver cancer followed by a PD-1 checkpoint inhibitor (nivolumab).
- Trial name
- TATE-PD1 (NCT03259867)
- Testing
- Nivolumab Injectable Product, Trans-arterial tirapazamine embolization
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Teclison Ltd.
Gastric Carcinoma
Clinical Study of Nab-paclitaxel Combined With Toripalimab in Local Advanced or Metastatic G/GEJ Carcinoma
This study is to evaluate the efficacy and safety of Albumin-bound paclitaxel combined with Toripalimab as first-line/second-line treatment of local advanced or metastatic gastric or gastroesophageal junction carcinoma.
- Trial name
- NCT04443036
- Testing
- Albumin-Bound Paclitaxel, Toripalimab
- Where
- China
- Volunteers
- 44 people
- Sponsor
- China Medical University, China
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