Clinical trials: Gastric (Stomach) Cancer
Stomach Neoplasms, Gastric Cancer
Specialization in Gastric Cancer Surgery
Specialization is having competent and effective knowledge on a subject, and the tendency towards specialization is increasing due to the fact that it increases the success in the follow-up and treatment process of diseases.
- Trial name
- NCT05280665
- Testing
- Specialization
- Where
- Turkey (Türkiye)
- Volunteers
- 537 people
- Sponsor
- Karadeniz Technical University
Gastric Tumor
Flexible Endoscopy Biopsies for Submucous Tumors With a New Drill Instrument
The purpose of this study is to determine whether the newly constructed CE (Conformité Européenne) marked drill biopsy instrument for flexible endoscopes can make possible representative biopsies of the increasing numbers of…
- Trial name
- NCT02161029
- Testing
- Flexible drill biopsy instrument, conventional biopsy instrument
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Region Skane
Somatostatin Receptor Positive, NETs
Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors
The purpose of the study is to determine the appropriate pediatric dosage and evaluate the pharmacokinetics (PK) and safety of Lutetium Lu 177 Edotreotide Targeted Radiopharmaceutical Therapy (RPT) as a monotherapy or following…
- Conditions
- Somatostatin Receptor Positive, NETs, Lymphoma, Solid Tumor
- Trial name
- KinLET (NCT06441331)
- Testing
- Lutetium Lu 177-Edotreotide, Amino Acid Solution
- Where
- 9 sites in United States, France and 1 more
- Volunteers
- 20 people
- Sponsor
- ITM Solucin GmbH
Breast Cancer, Esophageal Cancer
Brodalumab in the Treatment of Immune-Related Adverse Events
The purpose of this study is to test the safety and effectiveness of using brodalumab in patients who develop side effects from cancer immune therapy.
- Conditions
- Breast Cancer, Esophageal Cancer, Kidney Cancer, Lung Cancer
- Trial name
- NCT06673329
- Testing
- Brodalumab, CT scan
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Brian Henick, MD
Stomach Neoplasms
Randomized Controlled Trials Comparing Clinical Outcomes of 3D Versus 2D Laparoscopic Surgery for Gastric Cancer
The purpose of this study is to explore the feasibility, safety, and efficacy of 3D Laparoscopic Surgery for Gastric Cancer. The patients with gastric adenocarcinoma (cT1-4aN0-3M0) were studied.
- Trial name
- NCT02327481
- Testing
- 3D Laparoscopic Surgery, 2D Laparoscopic Surgery
- Volunteers
- 438 people
- Sponsor
- Fujian Medical University
Gastric Cancer
Phase II Study of Pemetrexed in Advanced or Recurrent Gastric Cancer After Chemotherapy
This phase II trial aimed to assess the efficacy and safety of pemetrexed in patients with pretreated metastatic gastric cancer.
- Trial name
- NCT01953419
- Testing
- Pemetrexed disodium
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Sun Yat-sen University
Locally Advanced Gastric Cancer
Effect of Adjuvant Chemotherapy Cycles on Patients With Node-negative Gastric Cancer Following Neoadjuvant Chemotherapy
To explore the effect of adjuvant chemotherapy cycles on the prognosis of this specific patient with lymph node-negative gastric cancer following neoadjuvant chemotherapy.
- Trial name
- NCT06277453
- Testing
- surgery
- Where
- China
- Volunteers
- 219 people
- Sponsor
- Fujian Medical University
Older Adults, Gastro-Intestinal Cancer
PeRsonalizing the Approach to the Oncologic Frail Individual Through Tailored Assessment and Intervention (PROFIT Study)
The PROFIT study has two complementary aims. The first aim is to compare, in a cohort study enrolling N=257 older adults (>65 years) with lung, gastrointestinal and prostate cancer, different easy measures of frailty (Geriatric 8…
- Conditions
- Older Adults, Gastro-Intestinal Cancer, Prostate Cancer, Lung Cancer
- Trial name
- PROFIT (NCT05319145)
- Testing
- Intervention group, Control group
- Where
- 3 sites in Andorra, Spain
- Volunteers
- 268 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Gastric Adenocarcinoma, Advanced Solid Tumors
A Study of AK104, a PD-1/CTLA-4 Bispecific Antibody, for Advanced Solid Tumors or With mXELOX/XELOX as First-line Therapy for Advanced Gastric or GEJ Adenocarcinoma
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), immunogenicity, pharmacodynamics (PD) and anti-tumor activities of AK104，a PD-1/CTLA-4 bispecific antibody, when administered as a single…
- Conditions
- Gastric Adenocarcinoma, Advanced Solid Tumors, Gastroesophageal Junction Adenocarcinoma
- Trial name
- NCT03852251
- Testing
- AK104, Oxaliplatin, Capecitabine
- Where
- China
- Volunteers
- 338 people
- Sponsor
- Akeso
HER2-positive Gastric Cancer
ctDNA Screening in Advanced HER2 Positive Gastric Cancer
To identify molecular biomarker panel correlating with efficacy of trastuzuamb in advanced HER2 positive gastric cancer patients.
- Trial name
- NCT04520295
- Testing
- ctDNA screening
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Ruijin Hospital
Quality of Life, Oesophageal Cancer
Quality of Life After Oesophageal or Gastric Cancer Surgery
This study aim to assess quality of life of patients 0-5 years after oesophageal or gastric cancer surgery and to develop and test an information and support program aiming to enhance the patients quality of life (QOL) after…
- Conditions
- Quality of Life, Oesophageal Cancer, Gastric Cancer
- Trial name
- NCT01657175
- Testing
- Supportive care
- Where
- Sweden
- Volunteers
- 82 people
- Sponsor
- Region Skane
DNA Damage, Gastric Cancer
Prospective Validation of a DNA Damage Repair-Hippo Pathway Signature in Patients With Advanced Gastric Cancer
We envisioned a scenario where the interaction between the ATM-Chk2/ATR-Chk1 pathways and Hippo enables GC cells to overcome chemotherapy-induced death stimuli.
- Trial name
- NCT06204523
- Testing
- investigated biomarkers regarding the efficacy of first-line chemotherapy
- Where
- Italy
- Volunteers
- 167 people
- Sponsor
- Regina Elena Cancer Institute
Hepatocellular Carcinoma, Cholangiocarcinoma
Liver Embolization Approaches for Tumor Management
The goal of this evaluate short, medium and long term outcome of the different embolization techniques in patients with primary and secondary hepatic tumors.
- Conditions
- Hepatocellular Carcinoma, Cholangiocarcinoma, Metastatic Colon Cancer, Metastatic Cancer
- Trial name
- LEATUM (NCT05714124)
- Testing
- Embolization
- Where
- Italy
- Volunteers
- 580 people
- Sponsor
- IRCCS San Raffaele
Gastric Cancer, Adenocarcinoma
Study of IMC-1121B (Ramucirumab) With Best Supportive Care in Participants With Gastric Cancer and Adenocarcinoma
The purpose of this study is to gather information about the use of an investigational drug called Ramucirumab in adenocarcinomas of the stomach or gastroesophageal junction.
- Trial name
- NCT00917384
- Testing
- ramucirumab, Best Supportive Care (BSC)
- Where
- 161 sites in United States, Argentina and 28 more
- Volunteers
- 355 people
- Sponsor
- Eli Lilly and Company
Gastrectomy for Gastric Cancer
Lymph Node Staging System With a Novel Concept for Gastric Cancer: a Hybrid Type of Topographic and Numeric Ones
For staging the status of lymph node metastasis in gastric cancer, typographic based staging system was applied until last decade, especially in Eastern countries.
- Trial name
- NCT01961791
- Testing
- gastrectomy
- Where
- South Korea
- Volunteers
- 6,025 people
- Sponsor
- Yonsei University
Gastric Cancer, Peritoneal Carcinomatosis
Efficacy of HIPEC Combined With Systemic Chemotherapy and CRS on Peritoneal Metastases From Gastric Cancer
This project is a multi-center, prospective, randomized controlled clinical observation the safety and efficacy that stage IV limited peritoneal metastasis of gastric cancer patients accept hyperthermic intraperitoneal…
- Trial name
- NCT03179579
- Testing
- HIPEC with neoadjuvant chemotherapy, Systemic chemotherapy
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Shu-Zhong Cui
MSI-H Colorectal Cancer, Melanoma
Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors
This is an open-label, parallel group, non-randomized, multicenter phase II study to evaluate the efficacy of spartalizumab (cohorts 1 and 2) and tislelizumab (cohort 3) in monotherapy in patients with PD1-high-expressing tumors.
- Conditions
- MSI-H Colorectal Cancer, Melanoma, Anal Carcinoma, Mesothelioma
- Trial name
- ACROPOLI (NCT04802876)
- Testing
- Spartalizumab, Tislelizumab
- Where
- Spain
- Volunteers
- 184 people
- Sponsor
- SOLTI Breast Cancer Research Group
Gastroenteropancreatic Neuroendocrine Tumor
A Study of Famitinib in Patients With Advanced or Metastatic Gastroenteropancreatic Neuroendocrine Tumor
Famitinib is a tyrosin-inhibitor agent targeting at c-Kit, VEGFR2, PDGFR, VEGFR3, Flt1 and Flt3. Phase I study has shown that the toxicity is manageable.
- Trial name
- NCT01994213
- Testing
- Famitinib
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Gastric Cancer, Colorectal Cancer
A Phase 1 Study of SHR-A1811 in Patients With Selected HER2 Expressing Tumors
This is a single arm, open-label, dose escalation, PK expansion and efficacy expansion study of phase I. The purpose of this study is to assess the tolerability, safety, pharmacokinetics and immunogenicity of SHR-A1811 and…
- Trial name
- NCT04513223
- Testing
- SHR-A1811
- Where
- China
- Volunteers
- 101 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Gastric Cancer
Effect of Laparoscopy-Assisted Distal Gastrectomy for Locally Advanced Gastric Cancer
The purpose of this study is to evaluate the effect and safety of laparoscopy-assisted D2 radical surgery for distal advanced gastric cancer.
- Trial name
- SWEET (NCT02464215)
- Testing
- open surgery, laparoscopic surgery
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Peking University Cancer Hospital & Institute
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