Clinical trials: Gastric (Stomach) Cancer
Submucosal Tumor of Stomach
Endoscopic Full Thickness Resection Without Exposure to Peritoneum
This study evaluates the feasibility of endo-laparoscopic full-thickness resection with simple suturing technique which did not expose gastric mucosa to peritoneum (simple non-exposure EFTR) in patients with gastric tumor.
- Trial name
- NCT02764944
- Testing
- simple non-exposure EFTR
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- National Cancer Center, Korea
Metastatic Gastric Cancer, Surgery
Clinical Outcome of Palliative Surgery After Translational Therapy for Metastatic Gastric Cancer Versus Maintenance Chemotherapy for Metastatic Gastric Cancer
This single-center, prospective study was conducted to investigate the efficacy and safety of palliative surgery after translational therapy in the treatment of metastatic gastric cancer.
- Conditions
- Metastatic Gastric Cancer, Surgery, Chemotherapy
- Trial name
- NCT05230771
- Testing
- Palliative surgery after translational therapy, Chemotheraoy along
- Volunteers
- 120 people
- Sponsor
- Fujian Medical University
Tislelizumab, Chemotherapy
Tislelizumab Combined With Chemotherapy in First-line Treatment of AGC
This is a single-center, retrospective clinical study to evaluate the efficacy and safety of tislelizumab combined with first-line chemotherapy in the treatment of HER2-negative advanced gastric cancer.
- Conditions
- Tislelizumab, Chemotherapy, First-line, Gastric Cancer Stage IV
- Trial name
- NCT06034964
- Testing
- Tislelizumab
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Endometrial Cancer, Cervical Cancer
Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
The objective of this study is to evaluate the safety, tolerability, and efficacy of BL-M07D1 in patients with HER2 expressing advanced tumors.
- Conditions
- Endometrial Cancer, Cervical Cancer, Ovarian Cancer, Urothelial Carcinoma
- Trial name
- NCT06293898
- Testing
- BL-M07D1
- Where
- 26 sites in United States
- Volunteers
- 280 people
- Sponsor
- SystImmune Inc.
Gastric Cancer, Gastroesophageal Junction Cancer
Efficacy Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Against Chemotherapy in Stomach Cancer or Stomach/Esophagus Junction Cancer
The main purpose of this study is to compare how long patients with gastric or gastroesophageal junction cancer live after receiving nivolumab and ipilimumab or nivolumab and chemotherapy compared with patients receiving…
- Conditions
- Gastric Cancer, Gastroesophageal Junction Cancer, Esophageal Adenocarcinoma
- Trial name
- CheckMate649 (NCT02872116)
- Testing
- Nivolumab, Ipilimumab, Oxaliplatin
- Where
- 179 sites in United States, Argentina and 27 more
- Volunteers
- 2,031 people
- Sponsor
- Bristol-Myers Squibb
Gastric Cancer
Study of Anlotinib in Patients With Gastric Cancer(ALTER0503)
The purpose of this study is to compare the effects and safety of Anlotinib with placebo in patients with Gastric Cancer.
- Trial name
- NCT02461407
- Testing
- Anlotinib
- Where
- 38 sites in China
- Volunteers
- 378 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Gastrointestinal Neoplasm
Kinase Genotyping of Gastro Intestinal Stomach Tumors (GISTs) From Patients Enrolled in Pfizer A6181112 Phase IIIb Trial
The purpose of this study is to determine the genetic makeup of gastro intestinal stomach tumors (GISTs) from patients enrolled in the A6181112 phase IIIb trial.
- Trial name
- NCT00640692
- Sponsor
- Oregon Health and Science University
Liver Metastases
CAR-T Hepatic Artery Infusions or Pancreatic Venous Infusions for CEA-Expressing Liver Metastases or Pancreas Cancer
This is an open label, fixed dose, phase Ib trial of anti-CEA CAR-T cell infusions delivered via the hepatic artery or splenic vein using the Surefire Infusion System (SIS) for patients with CEA-expressing liver metastases or…
- Trial name
- HITM-SURE (NCT02850536)
- Testing
- anti-CEA CAR-T cells
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Roger Williams Medical Center
Gastric Cancer
NBI for Identifying Resection Margin Status in Gastric Cancer
As the proportion of early gastric cancer has been steadily increased in Korea, so has function-preserving surgery. The function preserving surgery is characterized by the minimized extent of gastrectomy, so this implies that…
- Trial name
- NCT02926716
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Ajou University School of Medicine
Gastric Cancer
A Retrospective Validations Microsatellite Instability (MSI) Testing v Mismatch Repair (MMR) in Gastric Adenocarcinoma
To compare the Idylla microsatellite instability test versus mismatch repair immunohistochemistry (IHC) in gastric adenocarcinoma.
- Trial name
- NCT04232020
- Testing
- Mismatch repair
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Royal Cornwall Hospitals Trust
Gastric Cancer
Low-dose Radiotherapy Combined With Chemotherapy and AK112 as Second-line Treatment in Patients With Advanced G/GEJ Cancer
The study aims to evaluate the efficacy and safety of the combination of albumin-bound paclitaxel and AK112 with low-dose radiotherapy in patients with gastric adenocarcinoma and gastroesophageal junction adenocarcinoma who have…
- Trial name
- NCT06791148
- Testing
- Low-dose radiotherapy, albumin-bound paclitaxel, AK112
- Where
- China
- Volunteers
- 45 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Gastric Cancer, Gastric Intestinal Metaplasia
Surveillance of Patients With Precancerous Lesions of the Stomach
The project will aim to identify and determine subgroups of patients with different risks of progression to gastric cancer and to assess appropriate follow-up intervals.
- Conditions
- Gastric Cancer, Gastric Intestinal Metaplasia, Gastric Atrophy, Gastric Dysplasia
- Trial name
- NCT03250091
- Testing
- Upper endoscopy with biopsies, Plasma/serum sampling, Biopsies for gastric microbiota
- Where
- Latvia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Latvia
Stomach Neoplasm, GastroEsophageal Cancer
PREACT Study: Locally Advanced Gastric Cancer, Chemoradiotherapy vs. Chemotherapy Followed by D2 Surgery and Adjuvant Chemotherapy
Although the incidence of gastric cancer has been substantially declining for several decades, it is still the sixth most common cancer and the fourth most frequent cause of cancer death worldwide.
- Conditions
- Stomach Neoplasm, GastroEsophageal Cancer, Adenocarcinoma, Locally Advanced Cancer
- Trial name
- PREACT (NCT03013010)
- Testing
- Tegafur-Gimeracil-Oteracil Potassium, Chemoradiotherapy, Gastric resection
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Shanghai Cancer Hospital, China
Bladder Cancer, Brain and Central Nervous System Tumors
Lapatinib and Paclitaxel in Treating Patients With Advanced Solid Tumors
RATIONALE: Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Bladder Cancer, Brain and Central Nervous System Tumors, Breast Cancer, Esophageal Cancer
- Trial name
- NCT00313599
- Testing
- lapatinib, paclitaxel
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of California, San Francisco
CAG - Chronic Atrophic Gastritis, EGC - Early Gastric Cancer
LCI in Chronic Atrophic Gastritis and Early Gastric Cancer
Color change is a useful marker for the endoscopic identification of chronic atrophic gastritis (CAG) and gastric cancer (GC). Several histopathological studies have suggested a correlation between certain gastrointestinal…
- Trial name
- NCT06152263
- Testing
- Compare color information and mucosal microvascular density
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Two Different Treatment Methods
Research On the Optimized Treatment Method For Apatinib's Cure Of Advanced Gastric Cancer
The investigators hope that after this research, two different treatment methods' curative effects for advanced gastric cancer can be assessed.
- Trial name
- NCT03334591
- Testing
- Apatinib
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Provincial Hospital
Gastric Cancer
Efficacy and Safety of Minimally Invasive D2+PAND Gastrectomy for Gastric Cancer With PAN Metastasis After Conversion Immunochemotherapy
This is a prospective, open-label, single-center, Phase II clinical trial. Thirty patients with HER2-negative gastric adenocarcinoma or gastroesophageal junction (GEJ) cancer, presenting with PAN metastasis (No.
- Trial name
- NCT07056010
- Testing
- curative minimally invasive gastrectomy with D2+PAND lymphadenectomy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Bleeding After GI Endoscopy
Endoscopic Application of Tranexamic Acid and Sucralfate in Gastrointestinal Tumor Bleeding: A Randomized Controlled Trial
Background Gastrointestinal bleeding is a common disease among the population in Taiwan, with gastrointestinal tumor bleeding accounting for 3-5% of cases.
- Trial name
- NCT07540026
- Testing
- 3g of sucralfate powder and 1.5g of tranexamic acid powder, Standard Treatment
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng-Kung University Hospital
Morbid Obesity, Hernia
Minimally Invasive Surgery (MIS) Database for the Purpose of Research
The Minimally Invasive Surgery Team (MIST) are establishing a separate research database to find out more about patient's undergoing minimally invasive surgery (laparoscopic , open and robot assisted) procedures at UCSD.
- Conditions
- Morbid Obesity, Hernia, Colorectal Cancer, Laparoscopy
- Trial name
- NCT00535990
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Gastric Cancer
Surgery for Obstructed Gastric Carcinoma
The goal of this clinical trial is to find the best treatment for obstructed gastric carcinoma in gastric cancer patients. It will include all patients with obstructed gastric cancer with different ages and sex who consented to…
- Trial name
- NCT07435025
- Testing
- palliative gastric resection, palliative bypass
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Zagazig University
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