Clinical trials: Gastric Bypass
Morbid Obesity
Banded Versus Non-banded Roux-en-Y Gastric Bypass
This is a prospective randomized Study comparing Weight loss, Esophageal Motility and Reflux in lap. Gastric Bypass vs. lap. Banded-Gastric Bypass using the A.M.I. Soft Gastric Bypass Band (B-Band.
- Trial name
- NCT01078181
- Testing
- gastric bypass
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Obesity, Type 2 Diabetes Mellitus
Metabolic Surgery Versus Medical Management for Resolution of Type II Diabetes
Best medical management and gastric bypass surgery is a way to treat diabetes as part of regular medical care (standard of care).
- Trial name
- NCT01044602
- Testing
- Laboratory evaluations, sleep study, Best Medical Management, Roux-en-Y gastric bypass surgery
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- David Bradley MD
Type 2 Diabetes Mellitus, Bariatric Surgery
Surgical Treatment of Type 2 Diabetes Mellitus in <35 Body Mass Index (BMI)
Thirty type 2 diabetic patients will be submitted to biliopancreatic diversion and 20 to gastric bypass. Subjects will be monitored during a 5 year period to assess the effects of the operations on diabetes control.
- Conditions
- Type 2 Diabetes Mellitus, Bariatric Surgery, Biliopancreatic Diversion, Gastric Bypass
- Trial name
- NCT00996294
- Testing
- biliopancreatic diversion, gastric bypass
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
MASLD
Hepatic Gene Response to Intravenous Glucose in Obese Patients With and Without MASLD Undergoing Bariatric Surgery
The goal of this clinical trial is to learn how the liver responds to sugar in people with obesity who are having bariatric surgery.
- Trial name
- GHAST (NCT07326865)
- Testing
- [6,6-D2]-labeled glucose (intravenous), Saline (0.9% sodium chloride infusion)
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Bariatric Surgery
Lexion AP 50/30 Warmed Humidified Real Time CO2 Insufflation vs Airseal Recirculated CO2/Air Insufflation in Minimally Invasive Bariatric (Gastric Bypass) Surgery
The purpose of this study is to To determine the effect of warm and humidified (WH) carbon dioxide (CO2) on post-operative pain/analgesia requirement in patients undergoing laparoscopic bariatric surgery.
- Trial name
- NCT05838300
- Testing
- Warm humidified CO2, Dry CO2
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- The University of Texas Health Science Center, Houston
Hyperinsulinemic Hypoglycemia, Postprandial Hypoglycemia
Treatment of Post-bariatric Hypoglycaemia
This is an investigator-initiated, proof-of-concept, randomised, double-blind, placebo-controlled, single-centre phase II study aiming to evaluate the efficacy, safety and tolerability of self-administered subcutaneous 120 µg…
- Trial name
- SHERRY (NCT04836273)
- Testing
- Dasiglucagon, HyoPen
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Filip Krag Knop
Type II Diabetes
The Effect of Gastric Bypass Surgery on Diabetes
This study will investigate the effects of gastric bypass surgery on type II diabetes. The study will recruit patients with type II diabetes having Roux-en-Y gastric bypass, patients without type II diabetes having Roux-en-Y…
- Trial name
- NCT01330251
- Where
- Finland
- Volunteers
- 41 people
- Sponsor
- University of Oulu
Obesity, Morbid Obesity
Studies of Biological Changes Related to Weight Loss After Gastric Bypass Surgery
Weight loss achieved by dieting induces multiple changes. These changes include a decrease in metabolic rate (the rate in which the body burns its calories), an increase in appetite and other physiological and hormonal changes…
- Conditions
- Obesity, Morbid Obesity, Weight Loss
- Trial name
- NCT00120562
- Testing
- Gastric Bypass Surgery
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Rockefeller University
Gastric Cancer
Study of Gastroduodenal Metallic Stent vs Gastrojejunostomy
Selection of the optimal treatment for gastric outlet obstruction in patients with radically unresectable gastric cancer remains controversial because previous studies comparing the two procedures had a small sample size as well…
- Trial name
- NCT02784470
- Testing
- gastroduodenal stent placement, gastrojejunostomy
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Asan Medical Center
Obesity
Tangji Gastric Bypass Stent Study for Obesity
The Gastric Bypass Stent System is intended to be used in weight loss treatment for obesity in patients with a BMI ≥ 30 kg/m2. In this clinical investigation the Sponsor seeks to demonstrate the safety and performance of the…
- Trial name
- NCT05938231
- Testing
- Gastric Bypass Stent System, Dietary Intervention
- Where
- 7 sites in China
- Volunteers
- 99 people
- Sponsor
- Hangzhou Tangji Medical Technology Co., Ltd.
Morbid Obesity, Weight Loss
Laparoscopic Gastric Bypass Versus Laparoscopic Banded Gastric Bypass Randomized Prospective Clinical Trial
This study try to identify differences in length of operation, weight loss and complications, between two different bariatric surgical techniques, the laparoscopic Roux-en-Y gastric bypass and the laparoscopic Roux-en-Y banded…
- Conditions
- Morbid Obesity, Weight Loss, Postoperative Complications
- Trial name
- LGB-vs-LbGB (NCT02939664)
- Testing
- Banded (with polypropylene mesh) gastric bypass, Gastric bypass
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Puerta de Hierro University Hospital
Nonalcoholic Fatty Liver Disease
Gastric Bypass Stent Small-Sample-Size Study For Nonalcoholic Fatty Liver Disease
Evaluate the preliminary effectiveness and safety of the Gastric Bypass Stent System in treating nonalcoholic fatty liver disease.
- Trial name
- NCT05495139
- Testing
- Gastric Bypass Stent System in Treatment of Patients with Nonalcoholic Fatty Liver Disease
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Hangzhou Tangji Medical Technology Co., Ltd.
Gastric Bypass
Prospective Trial Using Gastric Stapling Line Reinforcement With Seamguard in Roux-en-Y Gastric Bypass
Study objectives : Primary endpoint is to a assess the change in blood loss (originating from stapling the stomach) with the use of Seamguard reinforcement Secondary endpoint is to evaluate the difference in leak rate Methods …
- Trial name
- NCT01015157
- Testing
- Roux-en-Y laparoscopic gastric bypass for morbid obesity
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Clinique de l'Anjou
Obesity, Hypoglycemia Post Gastric Bypass Surgery
GLP1R-imaging in Post-RYGB Hypoglycemia
In order to evaluate the difference in beta cell mass in patients with and without hyperinsulinemic hypoglycemia after Roux en Y gastric bypass (RYGB) investigators aim to compare quantitative PET imaging of the pancreas between…
- Conditions
- Obesity, Hypoglycemia Post Gastric Bypass Surgery, Hyperinsulinemic Hypoglycemia
- Trial name
- NCT05597475
- Testing
- GLP-1R PET
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Obesity
Impact of Laparoscopic Gastric Bypass Surgery and Weight Reduction on Lower Esophageal Sphincter (LES)
The purpose with this study is to investigate whether gastric bypass surgery and the following weight reduction impact the tone in esophageal sphincters and the esophageal function.
- Trial name
- NCT01672034
- Testing
- Laparoscopic gastric bypass surgery
- Where
- Sweden
- Sponsor
- Örebro University, Sweden
Obesity, Morbid, Bariatric Surgery
Photographic Food Recognition and Meal Size Estimation Before and After Roux-en-Y Gastric Bypass
Direct measurements of changes in food selection in humans after RYGB have been limited by the unreliability of patients, which poses significant methodological and conceptual challenges to researchers and study design.
- Conditions
- Obesity, Morbid, Bariatric Surgery, Roux-en-Y Gastric Bypass, Food Preferences
- Trial name
- NCT04600596
- Testing
- Recording of food intake.
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Marco Bueter
Obesity, Cardiac Function
Severe Obesity: Bariatric Surgery vs. Life-Style-Intervention
The purpose of this study is to investigate the effects of weight loss induced by gastric bypass surgery in comparison to a psychotherapy-enhanced lifestyle intervention on cardiopulmonary performance and quality of life in…
- Conditions
- Obesity, Cardiac Function, Quality of Life
- Trial name
- WAS (NCT01352403)
- Testing
- Roux-en-Y gastric bypass, Psychotherapy-enhanced lifestyle intervention
- Where
- Germany
- Volunteers
- 93 people
- Sponsor
- University of Wuerzburg
Bariatric Surgery Candidate, Gastric Bypass
Assessment of Pouch Emptying With MRI After Roux-en-Y Gastric Bypass
A cross-sectional observational study in which pouch emptying rate is measured with MRI in good (TWL>35%) and bad responders (TWL<25%) two years after Laparoscopic Roux-en-Y Gastric Bypass (LRYGB).
- Conditions
- Bariatric Surgery Candidate, Gastric Bypass, Obesity, Morbid, Pouch Emptying
- Trial name
- MRI pouch (NCT06298162)
- Testing
- 2 years after RYGB, no intervention. MRI measurement. Observational.
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Rijnstate Hospital
Clinically Severe Obesity, Gastroesophageal Reflux Disease
Gastric Bypass After Previous Anti-reflux Surgery
The goal of this study is to describe the clinical presentation, indications, and operative treatment as well as assess the morbidity, mortality, and overall performance of revisional Roux-en-Y gastric bypass (RYGB) after either…
- Trial name
- RYGBafterARS (NCT01041105)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, San Francisco
Abdominal Pain
Chronic Abdominal Pain After Gastric Bypass
The study aims to explore patients perception of chronic abdominal pain after Roux en Y gastric bypass surgery for morbid obesity. The investigators aim to describe characteristics of symptoms of pain.
- Trial name
- NCT03455998
- Testing
- questionnaires
- Where
- Norway
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital