Clinical trials: Gastric Bypass
Type 2 Diabetes
Proteomics Study of Gastric Bypass Surgery to Treat Type 2 Diabetes Mellitus
The purpose of this study is to reveal the key proteins involved in gastric bypassing surgery which may effect the decreased glucose in type 2 diabetes patietns, and evaluate standard remission rate as well as cost-benefit of…
- Trial name
- NCT01870713
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- No. 150 Central Hospital of the Chinese People Liberation Army
Obesity and Overweight, Nutritional Deficiency
Nutritional Health and Satisfaction After Bariatric Surgery: a Five-Year Retrospective Study
A retrospective study analyzing long-term outcomes of metabolic bariatric surgery (MBS) with a focus on weight loss, nutritional deficiencies, and patient satisfaction over a five-year follow-up.
- Conditions
- Obesity and Overweight, Nutritional Deficiency, Bariatric Surgery
- Trial name
- NCT06664580
- Testing
- Metabolic Bariatric Surgery Procedures
- Volunteers
- 249 people
- Sponsor
- San Raffaele Telematic University
Obesity, Bariatric Surgery Candidate
Preoperative Use of a Magnetically Controlled Capsule Endoscopy in Patients Undergoing Bariatric Surgery
The goal of this clinical trial is to test if a swallowable camera capsule can safely examine the upper digestive tract in people preparing for weight loss surgery.
- Conditions
- Obesity, Bariatric Surgery Candidate, Hypertension, Diabetes
- Trial name
- NAVICAM (NCT07587437)
- Testing
- Magnetically Controlled Capsule Endoscopy (MCCE)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Jerry Dang
Obesity, Weight Loss
Use of MCT Oil for Enhancement of Weight Loss in Obese Patients
Twelve obese patients approved for gastric bypass surgery will be randomized to either receive an MCT-based or LCT-based liquid diet for a 4 week period. These diets will be identical except for the quality of the fat.
- Trial name
- NCT00207272
- Testing
- 1170-1870 kcal/day liquid diet, Gastric bypass surgery, Biopsy.visceral adipose tissue
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Boston Medical Center
Obesity, Morbid, Weight Loss
Common Limb Length in One-anastomosis Gastric Bypass
Evaluation of the effect of the common limb length on the outcome of laparoscopic single anastomosis gastric bypass in morbidly obese patients.
- Conditions
- Obesity, Morbid, Weight Loss, Bariatric Surgery Candidate
- Trial name
- NCT04357119
- Testing
- One-anastomosis gastric bypass
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Hypoglycemia
CREON for the Treatment of Post-RYGB Hypoglycemia
Hypoglycemia is an increasingly recognized complication of Roux-en-Y gastric bypass (RYGB) that is poorly understood and difficult to treat.
- Trial name
- NCT02733848
- Testing
- Creon, Diet
- Volunteers
- 5 people
- Sponsor
- East Carolina University
Obesity
Bariatric Surgery: Microbiome & Diabetes
This study is a prospective cohort study, following 80 morbidly obese patients undergoing bariatric surgery, specifically Roux-en-Y gastric bypass (RYGB).
- Trial name
- NCT03723486
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Roux en Y Gastric Bypass
A Comparison of Sustained and Extended Release Bupropion Following Bariatric Surgery
This study is being conducted to evaluate how the body absorbs and processes the sustained release (SR) and extended release (XL) medication bupropion (Wellbutrin®).
- Trial name
- NCT02173886
- Testing
- Bupropion SR and XL
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- North Dakota State University
Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis
Study of the Link Between MASH ( Metabolic Dysfunction-Associated Steatohepatitis) and MAMs (Mitochondria-Associated Membranes ) Alteration in Patients Undergoing Bariatric Surgery - MAMBA
The main research hypothesis is that alterations in the communication between the endoplasmic reticulum (ER) and the mitochondria at contact sites called mitochondria-associated membranes (MAMs) occurs in different hepatic cell…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis, Sleeve Gastrectomy, Gastric Bypass Surgery
- Trial name
- MAMBA (NCT06868992)
- Testing
- Bariatric surgery (Sleeve Gastrectomy or Gastric Bypass)
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Obesity With Complications, Morbid Obesity
Bariatric Surgery and Reactive Hypoglycemia
Bariatric surgery has long been recognized as an effective treatment for grade 3 or grade 2 obesity associated with complications.
- Conditions
- Obesity With Complications, Morbid Obesity, Reactive Hypoglycemia, Bariatric Surgery
- Trial name
- NCT01581801
- Testing
- Gastric Bypass, Sleeve Gastrectomy
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Catholic University of the Sacred Heart
Obesity
PRebiotic to IMprovE Calcium Absorption
Gastric bypass surgery is a highly effective treatment for obesity, but it has negative effects on skeletal health, due in part to a dramatic decline in intestinal calcium absorption capacity.
- Trial name
- PRIME (NCT03272542)
- Testing
- Prebiotic: soluble corn fiber
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- San Francisco Veterans Affairs Medical Center
Severe Obesity, Renal Failure
Obesity Surgery and Kidney Transplant for Patients With Obesity and Renal Failure
Gastric Bypass followed by renal transplantation is superior to medical management followed by renal transplant for patients with severe obesity and renal failure.
- Trial name
- NCT02128802
- Testing
- Gastric Bypass, Weight Loss Program
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vanderbilt University Medical Center
Diabetes Mellitus, Type II
Mechanisms of Glycemic Improvement After Gastrointestinal Surgery
This study is designed as a prospective clinical trial aimed at investigating the mechanisms behind observed improvements in type 2 diabetes mellitus (T2DM) following bariatric surgery.
- Trial name
- NCT01025999
- Testing
- No intervention
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Washington
Obesity and Overweight, Bariatric Surgery (Gastric Bypass)
Protein Requirements After Bariatric Surgery
The study investigates protein requirements at least 1 year after gastric bypass surgery in adult males, to investigate whether protein requirements are elevated compared to protein requiremens for the general populaiotn.
- Conditions
- Obesity and Overweight, Bariatric Surgery (Gastric Bypass), Protein Requirement
- Trial name
- PROXY (NCT06853652)
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obesity
Strength Training Following Gastric Bypass for Obesity
We will assess whether undesirable loss of lean tissue following gastric bypass surgery for obesity can be minimized by protein supplementation and exercise training.
- Trial name
- NCT00065013
- Testing
- strength training
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Stomach Neoplasms, Gastric Outlet Obstruction
Malignant Gastric Outlet Obstruction Study With Stomach Partitioning (GO-PART)
The goal of this clinical trial is to evaluate whether stomach-partitioning gastrojejunostomy (SPGJ) more effectively reduces postoperative delayed gastric emptying (DGE) compared to conventional gastrojejunostomy (CGJ) in…
- Trial name
- GO-PART (NCT07749326)
- Testing
- Conventional Gastrojejunostomy, Stomach-Partitioning
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Gyeongsang National University Hospital
Morbid Obesity
Comparison of Mini Gastric Bypass and Roux-en-Y Gastric Bypass
This study compares Roux-en-Y gastric bypass with single anastomosis gastric bypass in a randomized prospective setting. This study also adresses the issue of bile reflux after MGB.
- Trial name
- RYSA (NCT02882685)
- Testing
- Roux-en-y gastric bypass, Single anastomosis gastric bypass
- Where
- 2 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Helsinki University Central Hospital
Obesity
A Banded One Anastomosis Gastric Bypass With Use Shape-memory Ring Versus Non-banded One Anastomosis Gastric Bypass
Background and study aims: Currently, the gastric bypass is increasingly performed in the version of the mini gastric bypass (MGB). Another name for the procedure: one anastomosis gastric bypass (OAGB).
- Trial name
- MEMORING (NCT04762849)
- Testing
- Laparoscopic one anastomosis gastric bypass, A shape-memory ring for adjustable gastric banding
- Where
- Kazakhstan
- Sponsor
- University Medical Center, Kazakhstan
Morbid Obesity
Clinical Trial Between Laparoscopic Gastric Bypass and Laparoscopic Vertical Banded Gastroplasty for Morbid Obesity
This is a randomized clinical trial assessing the outcome of two surgical strategies to treat severe obesity; laparoscopic gastric bypass and laparoscopic VBG.
- Trial name
- LOK (NCT01639677)
- Testing
- Laparoscopic gastric bypass, Laparoscopic VBG
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Morbid Obesity
Banded Versus Non-banded Roux-en-Y Gastric Bypass
This is a prospective randomized Study comparing Weight loss, Esophageal Motility and Reflux in lap. Gastric Bypass vs. lap. Banded-Gastric Bypass using the A.M.I. Soft Gastric Bypass Band (B-Band.
- Trial name
- NCT01078181
- Testing
- gastric bypass
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna