Clinical trials: Gastric Bypass
Patients Undergoing Elective Coronary Artery Bypass Graft
Lansoprazole Preventing Gastroduodenal Stress Ulcerations
The primary objective of this study is to determine whether lansoprazole, administered intravenously, can protect patients undergoing cardiac surgery from the development of and/or progression of previously undetected acid/peptic…
- Trial name
- NCT00220909
- Testing
- Lansoprazole
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Temple University
Morbid Obesity
Laparoscopic Revision of an Enlarged Gastric Outlet After Gastric Bypass
The purpose of this study is to determine if laparoscopic plication of a gastrojejunostomy is an effective surgical option for the Roux-en-Y gastric bypass patient who has regained weight due to a dilated gastric stoma.
- Trial name
- NCT01116284
- Testing
- Revision of gastric bypass
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Baystate Medical Center
Type2 Diabetes, Complication of Bariatric Procedure
Efficacy and Safety of One-anastomosis Versus Roux-en-Y Gastric Bypass for Type 2 Diabetes Remission
Diabetes mellitus (T2DM) is the most common complication of obesity patients. According to previous literature reports, weight loss and metabolic surgery are powerful means to treat obesity complicated with T2DM.
- Trial name
- ORDER (NCT05015283)
- Testing
- The laparoscopic One-anastomosis gastric bypass will consist of:, The laparoscopic Roux-en-Y gastric bypass will consist of:
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Beijing Friendship Hospital
Obesity
Effects of OAGB and DJB-SG on 10-year and Lifetime Risks of MACE
Metabolic bariatric surgery (MBS) has demonstrated its efficacy in achieving sustainable weight loss and alleviating associated comorbidities.
- Trial name
- NCT06254339
- Testing
- OAGB, DJB-SG
- Volunteers
- 830 people
- Sponsor
- National Defense Medical Center, Taiwan
Hypoglycemia, Glucose Metabolism Disorders
Efficacy and Safety of Dasiglucagon for Treatment of Post-bariatric Hypoglycemia in Roux-en-Y Gastric Bypass (RYGB) Operated Adults
The objective of the trial is to assess the effect of single subcutaneous doses of dasiglucagon versus placebo on post-prandial plasma glucose nadir following a Mixed Meal Test in Roux-en-Y Gastric Bypass (RYGB) subjects
- Trial name
- NCT04824872
- Testing
- Dasiglucagon
- Sponsor
- Zealand Pharma
Morbid Obesity, Metabolic Syndrome X
Randomized Comparison of Laparoscopic Sleeve Gastrectomy and Gastric Bypass for Morbid Obesity
Bariatric surgery is the most effective treatment for morbid obesity. Roux-en-Y gastric bypass (RYGB) is a bariatric procedure with known safety and effectiveness.
- Conditions
- Morbid Obesity, Metabolic Syndrome X, Diabetes Mellitus, Dyslipidemia
- Trial name
- NCT01806506
- Testing
- Laparoscopic sleeve gastrectomy, Roux-en-Y Gastric Bypass
- Where
- Poland
- Volunteers
- 72 people
- Sponsor
- Medical University of Warsaw
Obesity, GERD
One Anastomosis Gastric Bypass With Excluded Stomach Fundoplication: FundoRing vs Nissen vs OAGB Without Fundoplication
Background and study aims: Currently, one anastomosis Gastric Bypass (OAGB) is a common bariatric procedure. Obesity and gastroesophageal reflux disease (GERD) are steadily increasing world weight and antireflux surgery must be…
- Trial name
- FundoRing (NCT04828733)
- Testing
- laparoscopic one anastomosis gastric bypass with excluded stomach fundoplication: FundoRingOAGB and suture cruroplasty, laparoscopic one anastomosis gastric bypass with excluded stomach Nissen fundoplication and suture cruroplasty, Standard laparoscopic one anastomosis gastric bypass with cruroplasty. Not used fundoplication.
- Where
- Kazakhstan
- Volunteers
- 150 people
- Sponsor
- The Society of Bariatric and Metabolic Surgeons of Kazakhstan
Obesity, Bariatric Surgery
Evaluation of the Dietary Supplement Refill Bypass to Reduce Nutritional Deficiencies of Patients Who Underwent Bariatric Surgery
This is a cohort, observational, prospective, multicenter, longitudinal study. 100 patients will be followed postoperatively for a period of 12 months.
- Trial name
- Refill (NCT02440087)
- Testing
- Refill Bypass
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Refill France
Obesity
Adipose Secretory Function in Patients Before & After Laparoscopic Surgery
The central hypothesis of our study is that metabolic and hemodynamic improvements following gastric bypass surgery are mediated by downregulation of inflammation-related adipokines produced by the intra-abdominal adipose tissue…
- Trial name
- NCT00495599
- Testing
- Cytokines assessed from fat tissue
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
GERD
A Prospective Blinded Randomized Study Comparing Laparoscopic Sleeve Gastrectomy and Laparoscopic Roux-en-y Gastric Bypass and Their Effect on Gastro-Esophageal Reflux Disease Using 24 Horus pH Monitoring
Obesity has become a significant health problem in Canada. It is known to be a risk factor for many diseases, including Gastro-Esophageal Reflux Disease (GERD).
- Trial name
- GERD (NCT02142998)
- Testing
- 24 pH monitoring, Esophageal Manometry:
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Complications of Diabetes Mellitus
Clinical Study on Metabolic Surgery Compared to the Best Clinical Treatment in Patients With Type 2 Diabetes Mellitus
This is a prospective, open, randomized study involving 100 patients with microvascular complications of type 2 diabetes mellitus and obesity, who will undergo gastric bypass (Roux-en-Y gastric bypass ARM A) or receive best…
- Trial name
- MOMS (NCT01821508)
- Testing
- Clinical Treatment, Roux-En-Y gastric bypass surgery
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Hospital Alemão Oswaldo Cruz
Obesity
Postprandial Nutrient Homeostasis Before and After Weight Loss Induced by Low-calorie Diet or RYGB
The purpose of this study is to compare the metabolic responses to low-carbohydrate and standard-carbohydrate meals in African Americans and non-Hispanic White adults with obesity and the effect of weight loss induced by…
- Trial name
- FGB (NCT03091725)
- Testing
- Roux-en-Y gastric bypass surgery, Low-calorie diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity
Microenvironment of Adipose Tissue in Endocannabinoid System
The purpose of this study is examine the relationship between adipose tissue inflammation and activation of the endocannabinoid system before and after Roux-en-Y gastric bypass surgery.
- Trial name
- NCT00978289
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vanderbilt University
Coronary Artery Disease, Left Ventricular Systolic Dysfunction
Preoperative Gastric Ultrasound and Left Ventricular Function in Coronary Artery Bypass Surgery
This study aims to investigate whether reduced heart function is associated with differences in stomach contents before elective coronary artery bypass graft (CABG) surgery.
- Conditions
- Coronary Artery Disease, Left Ventricular Systolic Dysfunction, Gastric Contents
- Trial name
- NCT07898215
- Testing
- Gastric Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Adiyaman University
Morbid Obesity
Effect of Exercise Before Gastric Bypass
Exercise training is proved to protect against premature cardiovascular mortality. Additionally there is evidence that relatively high exercise intensity may be an important factor for improving aerobic capacity and endothelial…
- Trial name
- NCT01042002
- Testing
- High intensity exercise
- Where
- Norway
- Volunteers
- 43 people
- Sponsor
- Norwegian University of Science and Technology
Complications After Gastric Bypass Operation
Complications After Bariatric Surgery Based, a Questionnaire Survey
The number of obese is increasing rapidly. Bariatric surgery is used to a greater and greater extent as treatment of obesity to obtain a greater and more permanent weight loss.
- Trial name
- NCT01930851
- Testing
- Gastric bypass operation
- Where
- Denmark
- Volunteers
- 1,429 people
- Sponsor
- University of Aarhus
Obesity, Bone Loss
The Effect of Gastric Bypass Surgery on Gut Hormones Related to Bone Remodeling and Intestinal Growth.
The overall purpose is to explore the link between the gut and the bones by investigating meal stimulated changes in the blood level of a number of hormones and markers related to intestinal growth and bone turnover in patients…
- Trial name
- NCT01700686
- Testing
- Meal test and dexa scan
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- University of Copenhagen
Obesity
Short-term Investigation of Resveratrol on Fat Metabolism in Morbidly Obese Women Undergoing Gastric Bypass Surgery
The purpose of this study is to investigate potential metabolic effects of resveratrol in morbidly obese women undergoing gastric bypass surgery.
- Trial name
- NCT01826279
- Testing
- Resveratrol
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- University of Aarhus
Surgical Technique
Impact of Side to Side Gastrojejunostomy on the Rate of Delayed Gastric Emptying After Pancreaticoduodenectomy (IPAD)
Prospective bi-centric randomized open-label study comparing side to side and end to side gastrojejunostomy in pancreaticoduodenectomy
- Trial name
- IPAD (NCT04742166)
- Testing
- Reconstruction
- Where
- 2 sites in France
- Volunteers
- 166 people
- Sponsor
- Rennes University Hospital
Obesity, Bariatrics
Ketamine and Propofol Combination Versus Propofol for Upper Gastrointestinal Endoscopy
Propofol is one of the most popular anesthetic drugs used for sedation during upper gastrointestinal endoscopies due to its quick onset and quick resolution of symptoms allowing patients to leave the hospital sooner.
- Conditions
- Obesity, Bariatrics, Sleep Apnea Syndromes, Gastric Bypass
- Trial name
- NCT02643979
- Testing
- Ketofol, Propofol, Saline
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai