Clinical trials: Gastric Bypass
Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass
Laparoscopic Revision of Jejunoileal Bypass to Gastric Bypass
This study objectives are the following. To describe the updated clinical presentation, indications, and multidisciplinary medical management of patients with a failed and/or complicated jejunoileal bypass (JIB).
- Conditions
- Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass, Nutritional Complications After Jejunoileal Bypass, Obesity Recidivism
- Trial name
- JIB-to-RYGB (NCT01040533)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Francisco
Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis
Metabolic Flux Analysis in Metabolic Dysfunction-Associated Steatotic Liver Disease
This prospective, single-center pilot study will evaluate metabolic flux dysregulation in adults with obesity and suspected or confirmed metabolic dysfunction-associated steatotic liver disease (MASLD) who are scheduled for…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis, Obesity, Bariatric Surgery
- Trial name
- MASLD (NCT07760909)
- Testing
- Bariatric surgery, Stable isotope tracer infusion, MRI/MRE
- Volunteers
- 20 people
- Sponsor
- Vanderbilt University Medical Center
Bariatric Surgery
Understanding Hypoglycaemia After Bariatric Surgery
Postprandial hyperinsulinaemic hypoglycaemia is an increasingly recognized adverse side effect of bariatric surgery. Affected individuals experience low glucose levels 1-3 hours after intake of meals, accompanied by symptoms such…
- Trial name
- HYPOBAR1 (NCT03609632)
- Testing
- Dietary Supplement: Glucose
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Morbid Obesity
Sleeve Gastrectomy Versus One-anastomosis Gastric Bypass: Randomized Trial
Hormonal changes after SG and OAGB involve alterations in the levels of many enteric hormones, among these hormones are ghrelin and glucagon-like peptide-1 (GLP-1).
- Trial name
- NCT04134156
- Testing
- sleeve gastrectomy, one anastomosis gastric bypass
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Type 2 Diabetes
Laparoscopic Bariatric Surgery to Treat Type 2 Diabetes in Obese Patients
A large number of research studies on people who were morbidly obese (extremely overweight), and had bariatric surgery (anti-obesity surgery) have shown that patients who were diabetic before surgery often experienced significant…
- Trial name
- NCT00428571
- Testing
- laparoscopic gastric bypass surgery, laparoscopic adjustable gastric banding, Intensive Medical Management
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Hamilton Health Sciences Corporation
Bariatric Surgery Candidate, GERD
9-Step Magnetic Bariatric Revisional Surgery
RYGB represents one of the best alternatives for weight loss in obese patients achieving a weight loss of up to 60% and a resolution of comorbidities of 70%.
- Conditions
- Bariatric Surgery Candidate, GERD, Revisional Bariatric Surgery
- Trial name
- NCT04945304
- Testing
- magnetic bariatric surgery, Magnetic gastric bypass
- Where
- Venezuela
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Unidad Internacional de Cirugia Bariatrica y Metabolica
Obesity
Oral Glucosestimulation After Gastric Bypass Surgery
The objective of this study is to examine gastric emptying and satiety hormones after oral glucose stimulation in 2 different concentrations in morbidly obese patients after Roux-en-Y-gastric-Bypass.
- Trial name
- NCT01851616
- Testing
- 25g of glucose in 200ml tap water, given orally (plus 50 mg 13C-sodium acetate), 10g Glucose in 200ml tap water given orally (plus 50 mg 13C-sodium acetate)
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- University Hospital, Basel, Switzerland
Diabetes Mellitus Type 2 in Obese
Impact of Long Alimentary Limb or Long Biliary Limb Roux-en-Y Gastric Bypass on Type 2 Diabetes Remission in Severely Obese Patients.
In patients with type 2 diabetes, Roux-en-Y gastric bypass (RYGB), which excludes a portion of the stomach and the proximal intestine from the alimentary circuit, improves glucose metabolism more rapidly and more extensively than…
- Trial name
- PRECI-Surg (NCT03821636)
- Testing
- Standard Roux-en-Y gastric bypass, Long alimentary limb Roux-en-Y gastric bypass
- Where
- 4 sites in France
- Volunteers
- 396 people
- Sponsor
- University Hospital, Lille
Gastric Bypass
Prospective Trial Using Gastric Stapling Line Reinforcement With Seamguard in Roux-en-Y Gastric Bypass
Study objectives : Primary endpoint is to a assess the change in blood loss (originating from stapling the stomach) with the use of Seamguard reinforcement Secondary endpoint is to evaluate the difference in leak rate Methods …
- Trial name
- NCT01015157
- Testing
- Roux-en-Y laparoscopic gastric bypass for morbid obesity
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Clinique de l'Anjou
Morbid Obesity
An Evaluation of the Outcomes of Bariatric Surgery - a Cohort Study
A prospective bariatric database was carried out in the Department of Digestive and Endocrine Surgery at the University Hospital of Strasbourg, France, starting in January 1996.
- Trial name
- ChirBar (NCT02811900)
- Testing
- Roux en Y gastric bypass, Sleeve gastrectomy, Gastric banding
- Where
- France
- Volunteers
- 10,000 people
- Sponsor
- IHU Strasbourg
Weight Loss, Obesity
Early Intervention for Morbidly Obese Patients After Roux-en-Y Gastric Bypass (RYGB) Surgery
Purpose and objective: To identify in the early post-operative period following laparoscopic Roux-en-Y gastric bypass patients likely to fail to progressively lose weight in expected fashion, and to institute intervention and…
- Trial name
- Back on Track (NCT01329692)
- Testing
- Lifestyle counseling
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Duke University
Vitamin D Deficiency, Gastrointestinal Diseases
Ultraviolet Light And Vitamin D In Subjects With Fat Malabsorption Or After Gastric Bypass Surgery
Patients with fat malabsorption due to Crohn's disease, ulcerative colitis, or other causes including cystic fibrosis, among others, or who have undergone gastric bypass have increased incidence of vitamin D deficiency relative…
- Trial name
- NCT01910792
- Testing
- Sperti Lamp
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Boston University
Type 2 Diabetes Mellitus - Poor Control
Efficacy and Safety Study of Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) to Treat Type 2 Diabetes Mellitus
Type 2 diabetes mellitus (T2DM) resolution in morbidly obese patients following bariatric surgery suggests the efficacy of metabolic surgery in non-morbidly obese patients (body mass index [BMI]<35 kg/m2).
- Trial name
- ADSMT-1 (NCT01277900)
- Testing
- Laparoscopic Roux en Y gastric Bypass
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- Asia Metabolic Surgery Research Group
Morbid Obesity, Inactivity
Effect of Physical Activity on Weight Loss and Cardiovascular Risk Factors After Gastric Bypass
The aim of this study is to increase our knowledge about the effect of physical activity in patients who have undergone gastric bypass surgery. The study will provide novel information in two areas.
- Trial name
- NCT01690728
- Testing
- Physical Activity
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Obesity
5 and 7-year Follow-up of the YOMEGA Trial Cohort
Over the last 40 years, the Roux-en-Y Gastric Bypass (RYGB) has been the gold standard in the surgical management of morbid obesity. and is a validated bariatric procedure in France.
- Trial name
- YOMEGA 5-7y (NCT05549271)
- Testing
- Laparoscopic Mini-gastric bypass, Laparoscopic Roux-en-Y Gastric ByPass (RYGBP)
- Where
- 9 sites in France
- Volunteers
- 248 people
- Sponsor
- Hospices Civils de Lyon
Obesity (BMI > 35) and Diabetes Mellitus, Obesity (BMI > 35) and Dyslipemia
Preoperative Optimization With Tirzepatide, Ketogenic Diet, or Standard Care Before One Anastomosis Gastric Bypass Surgery
This study compares three preoperative strategies before one anastomosis gastric bypass(OAGB) for severe obesity. Participants will be assigned to receive either tirzepatide medication for 60 days, a ketogenic diet for 4 weeks…
- Conditions
- Obesity (BMI > 35) and Diabetes Mellitus, Obesity (BMI > 35) and Dyslipemia, Obesity (BMI > 35) and High Blood Pressure
- Trial name
- OPTI-OAGB (NCT07622992)
- Where
- Italy
- Volunteers
- 96 people
- Sponsor
- Mario Musella MD
Morbid Obesity, Metabolic Syndrome X
Randomized Comparison of Laparoscopic Sleeve Gastrectomy and Gastric Bypass for Morbid Obesity
Bariatric surgery is the most effective treatment for morbid obesity. Roux-en-Y gastric bypass (RYGB) is a bariatric procedure with known safety and effectiveness.
- Conditions
- Morbid Obesity, Metabolic Syndrome X, Diabetes Mellitus, Dyslipidemia
- Trial name
- NCT01806506
- Testing
- Laparoscopic sleeve gastrectomy, Roux-en-Y Gastric Bypass
- Where
- Poland
- Volunteers
- 72 people
- Sponsor
- Medical University of Warsaw
Obesity
Comparison of Gastric Bypass and AspireAssist Aspiration Therapy for Treatment of Morbid Obesity
The purpose of this study is to compare Gastric Bypass and AspireAssist Aspiration Therapy over 5 years of treatment with regards to weight loss, quality of life, complications, adverse events, and health economics.
- Trial name
- NCT02142257
- Testing
- Gastric Bypass, AspireAssist Aspiration Therapy
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Blekinge County Council Hospital
Type 2 Diabetes Mellitus, Insulin Resistance
Bariatric Surgery And Adipose Inflammation Dysfunction and Type 2 Diabetes Mellitus
The focus of this proposal is to define the mechanism by which bariatric surgery acutely improves insulin sensitivity. Our central hypothesis is that drastically reduced caloric intake early after Bariatric surgery improves the…
- Trial name
- NCT01882036
- Testing
- Gastric Bypass w/ matched hypocaloric diet, Hypocaloric diet
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Minnesota
Obese Patients, Bariatric Surgical Pain
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
Regional anesthesia is a technique in which a local anesthetic is injected near a nerve or spinal cord to block sensation, motor stimulation, and pain.
- Conditions
- Obese Patients, Bariatric Surgical Pain, Bariatric Surgery (Sleeve Gastrectomy ), Non-Opioid Pain Management
- Trial name
- NCT07084753
- Testing
- Levobupivacaine, Dexamethasone contained in the solution for thoracic paravertebral block, Adrenaline
- Where
- Croatia
- Volunteers
- 36 people
- Sponsor
- IVO JURISIC