Clinical trials: Gastric Bypass
Bariatric Surgery, Roux-en Y Gastric Bypass
Gastro-Intestinal Digestion and Physiology After Bariatric Surgery
The goal of this clinical trial is to characterize gastrointestinal digestion and physiology in patients after bariatric surgery, or people living with obesity.
- Conditions
- Bariatric Surgery, Roux-en Y Gastric Bypass, Sleeve Gastrectomy, Obesity & Overweight
- Trial name
- GIBa (NCT07286968)
- Testing
- Gastro-intestinal aspiration, Telemetric
- Where
- Netherlands
- Volunteers
- 51 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obesity (BMI > 35), Morbid Obesity
Predictive Value of Nutritional and Inflammatory Indices for Postoperative Complications After Bariatric Surgery
Bariatric surgery is an effective treatment for severe obesity, but postoperative complications remain an important cause of morbidity.
- Trial name
- BARI-NUTRI (NCT07747168)
- Testing
- Bariatric Surgery
- Where
- Greece
- Volunteers
- 600 people
- Sponsor
- G.Gennimatas General Hospital
Obesity, Laparoscopic Gastric Bypass Surgery
CURES: The Effect of Deep Curarisation and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity
The purpose of this study is to investigate if a deep neuromuscular block with a continuous infusion of rocuronium titrated to a post-tetanic count (PTC) of 1-2 responses combined with reversal of neuromuscular blockade with…
- Conditions
- Obesity, Laparoscopic Gastric Bypass Surgery, Surgical Conditions, Respiratory Function
- Trial name
- CURES (NCT01748643)
- Testing
- deep neuromuscular blockade with rocuronium, reversal with sugammadex, normal neuromuscular blockade reversal with rocuronium, reversal with neostigmine
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Ziekenhuis Oost-Limburg
Type 2 Diabetes, Obesity
Relationship Between Changes in Gut Hormones After Gastric Bypass and Gastric Banding and Improvements in Diabetes
The purpose of this study is to see how hormones that control blood sugar change in response to two different weight loss surgeries (gastric bypass and gastric banding).
- Conditions
- Type 2 Diabetes, Obesity, Bariatric Surgery
- Trial name
- NCT01153438
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Pennsylvania
Gastric Bypass, Morbid Obesity
Simplified Technique for Performing Laparoscopic Gastric Bypass
This study will include all eligible patients who have undergone or who will undergo a laparoscopic gastric bypass procedure at Madigan Army Medical Center using a specific surgical technique developed by the Principal…
- Trial name
- NCT06782256
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Madigan Army Medical Center
Type 2 Diabetes, Obesity
Intestinal Remodeling And Reprogramming of Glucose Metabolism Following Laparoscopic Roux-en-Y Gastric Bypass
The purpose of this study is to investigate small intestinal remodeling and reprogramming of glucose metabolism in patients with Type 2 Diabetes Mellitus (T2DM) who undergo laparoscopic Roux-en-Y Gastric Bypass (RYGB).
- Trial name
- NCT02288351
- Testing
- Mix Nutrient Meal, labs, Biopsy
- Sponsor
- Duke University
Head and Neck Squamous Cell Carcinoma
A Study of PF-00299804 When Given Through a Feeding Tube in Locally Advanced Head and Neck Squamous Cell Carcinoma
This is a study to assess how much of the investigational drug, PF-00298804, is in the blood stream over a period of time (called pharmacokinetic tests or PK) in patients with locally advanced head and neck squamous cell…
- Trial name
- NCT01484847
- Testing
- PF-00299804
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- University Health Network, Toronto
Morbid Obesity
Laparoscopic Gastric Bypass vs LAP-BAND for Treatment of Morbid Obesity
PURPOSE Obesity is a growing problem in the United States. Severe obesity, known as "morbid obesity", is defined as being 100 pounds in excess of ideal body weight.
- Trial name
- NCT00247377
- Testing
- Gastric bypass surgery, Lap-Band
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- University of California, Irvine
Bile Reflux
Omega Loop Gastric Bypass With And Without Anti-Reflux Sutures
This proposed trial is designed to answer the following questions: First, is biliary reflux to the distal esophagus present before OLGB and does it increase after the procedure? Second, does performing an OLGB with or without…
- Trial name
- NCT03097887
- Testing
- Omega Loop Gastric Bypass, Bilitec 2000™, V-Loc
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Contraception
Pharmacokinetics of Drospirenone Only Pills: A Pre- and Post-Bariatric Surgery Study
The purpose of this study is to investigate whether bariatric surgery affects Drospirenone only pills absorption
- Trial name
- NCT06345560
- Testing
- Drospirenone
- Where
- Thailand
- Volunteers
- 16 people
- Sponsor
- Chulalongkorn University
Obesity
Effect of Gastric Bypass Surgery on Pancreatic Islets and Incretin Function
The study aims at describing the acute and subacute changes after Roux-en-Y (RYGB) gastric bypass in insulin secretion from the beta cell and glucagon secretion from the alpha cell as well as the stimulatory effect of the…
- Trial name
- AB-CD-10 (NCT01559779)
- Where
- Denmark
- Volunteers
- 11 people
- Sponsor
- Hvidovre University Hospital
Morbid Obesity
Sleeve Gastrectomy Versus Gastric Bypass for Private Pay Patients Seeking Obesity Surgery
The purpose of this study is to determine laparoscopic sleeve gastrectomy is a safer surgery than the gastric bypass, gives similar weight losses and that the safety of gastric in private pay patients versus insurance patients…
- Trial name
- NCT01063959
- Testing
- Laparoscopic Sleeve Gastrectomy, Laparoscopic Gastric Bypass
- Where
- United States
- Sponsor
- Pennington Biomedical Research Center
Gastric Cancer, Type 2 Diabetes
Roux-en-Y Versus Billroth II Reconstruction After Subtotal Gastrectomy in Gastric Cancer Comorbid With Type II Diabetes
Gastric bypass improves glycemic levels in type 2 diabetes. However, the efficacy may be varied by different gastric-small intestine reconstruction used in the procedure.
- Trial name
- NCT01528059
- Testing
- Stomach-small intestine reconstruction
- Where
- China
- Volunteers
- 110 people
- Sponsor
- feng Zheng
Insulin Resistance, Obesity
Metabolism and Bariatric Surgery Study
The purpose of this study is to determine if diet-induced weight loss causes different changes in hormones that control appetite and glucose control than surgery-induced weight loss.
- Trial name
- NCT03371368
- Testing
- Roux-en-Y Gastric Bypass (RYGBP), Sleeve Gastrectomy (SG), Very Low Calorie Diet (VLCD)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Columbia University
Bypass, Gastric, Roux-en-Y Gastric Bypass
To Define the Role of GLP-1 for Improving Glucose Homeostasis in Humans Following Gastric Bypass Surgery
There is a marked and long-lasting improvement in glucose homeostasis that follows Roux-en-y gastric bypass surgery (RYGB) in humans.
- Conditions
- Bypass, Gastric, Roux-en-Y Gastric Bypass, Vertical Sleeve Gastrectomy, Gastric Banding
- Trial name
- NCT02204813
- Testing
- Lo-Xenin, Hi-Xenin, Extra Hi-Xenin
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Washington University School of Medicine
Obesity, Obesity, Morbid
Endoscopic Metabolic and Bariatric Therapies
This is a prospective collection of data from adult patients who have had an endoscopic metabolic and bariatric endoscopy procedure (EMBT) for primary or revision surgical procedures for obesity.
- Conditions
- Obesity, Obesity, Morbid, Obesity Associated Disorder, Bariatric Surgery Candidate
- Trial name
- EMBTs (NCT05725967)
- Testing
- Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical Procedures, Bariatric Surgery Procedures
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Christopher C. Thompson, MD, MSc
Obesity, Hypertension
Hemodynamics, Salt Sensitivity and Body Composition in Patients With Morbid Obesity
The purpose of this study is to evaluate the effect of high vs. low sodium intake on blood pressure and system hemodynamics in patients with morbid obesity and to evaluate the impact of laparoscopic gastric bypass on blood…
- Trial name
- NCT00998465
- Testing
- 24-hour blood pressure, Echocardiography, Inert gas rebreathing
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Bariatric Surgery Candidate, Kidney Stone
GI Oxalate Absorption
This study aims to learn more about how oxalate, a compound found in many foods, may affect a person's chances of forming kidney stones. Active participation in this study will last for around one week.
- Trial name
- NCT05356000
- Testing
- Special low-oxalate diet followed by all-day visit to University of Chicago research clinic
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Chicago
Anemia, Iron Deficiency
Iron Supplement to Improve Iron Status Following Bariatric Surgery
There is a high prevalence of iron deficiency in patients who undergo bariatric surgery and effective therapies are lacking. Thus, there is a critical need for an effective, non-invasive, and inexpensive form of iron…
- Trial name
- NCT02404012
- Testing
- Oral iron supplementation
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Indiana University
Bariatric Surgery Candidate
Extended Pouch Gastric Bypass vs One-anastomosis Gastric Bypass in Patients With BMI≥45
The classic RYGB is in most patients with a BMI ≥45 technically not feasible. Two alternatives are the Extended Pouch Gastric Bypass and the One Anastomosis gastric bypass.
- Trial name
- EXPANT (NCT06204939)
- Testing
- Randomizing for EPGB procedure, Randomizing for OAGB procedure
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- L. van Hogezand