Clinical trials: Gastric Bypass
Obesity
Return on Investment on Lap Gastric Bypass Regarding Quality of Life
The purpose of this study is to investigate the cost of treatment and adverse efffects therof corresponds to quality of life improvements and expected wheightloss.
- Trial name
- ROI-LGBP (NCT01986816)
- Where
- Sweden
- Sponsor
- Lund University
Obesity, Type 2 Diabetes Mellitus
Use of MCT Oil for Enhancement of Weight Loss and Glycemic Control in Obese Diabetic Patients
Phase I, 6 weeks: Intensive weight loss 42 obese subjects with type 2 diabetes mellitus or impaired fasting glucose (FBS greater than 100 mg/dl) and a patient at the Nutrition and Weight Management Center at Boston Medical Center…
- Trial name
- NCT00207233
- Testing
- MCT oil hypocaloric liquid diet, LCT hypocaloric liquid diet, Subcutaneous abdominal adipose tissue biopsy
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Boston Medical Center
Gastric Bypass, Obesity
Oversewing Staple Line of The Gastric Remnant
Background: Roux-en-Y gastric bypass (RYGB) is a surgery with low rate complications. However, it is not exempt from them, and 1-6% suffer complications such as postoperative bleeding.
- Trial name
- NCT04884230
- Testing
- Oversewing
- Where
- Venezuela
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Unidad Internacional de Cirugia Bariatrica y Metabolica
Post-bariatric Hypoglycaemia, Roux-en-Y Gastric Bypass
Forecasting and Preventing Post-Bariatric Hypoglycaemia WP 1
The overall aim of this study is to prevent hypoglycemic events in patients with hypoglycemia after a meal and to develop a sustainable hypoglycemia correction strategy.
- Trial name
- PBH Forecast (NCT05212207)
- Testing
- CGM, smartwatch, and electronic diary
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Lia Bally
Glucose Intolerance, Gastric Bypass Surgery
Examination of the Metabolic Effects of Direct Bile Salt Delivery to the Ileum in Humans
This project will evaluate distal intestinal bile salt administration in humans by deliving ursodeoxycholic acid (UDCA) into the terminal ileum of subjects with a pre-existing ileostomy and assessing several hormone levels…
- Trial name
- NCT03201952
- Testing
- Ursodeoxycholic Acid
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Morbid Obesity
Laparoscopic Revision of an Enlarged Gastric Outlet After Gastric Bypass
The purpose of this study is to determine if laparoscopic plication of a gastrojejunostomy is an effective surgical option for the Roux-en-Y gastric bypass patient who has regained weight due to a dilated gastric stoma.
- Trial name
- NCT01116284
- Testing
- Revision of gastric bypass
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Baystate Medical Center
Morbid Obesity
Bariatric Surgery Outcomes
The UCLA Metabolic and Bariatric Surgery Program (adult program) and the UCLA Fit for Healthy Weight Program (adolescent program) are committed to the care of morbidly obese patients. This study is observational.
- Trial name
- NCT01057784
- Testing
- Bariatric surgery.
- Where
- 2 sites in United States
- Sponsor
- University of California, Los Angeles
Type 2 Diabetes
Diet and Medical Therapy Versus Bariatric Surgery in Type 2 Diabetes
It is generally held that ß-cell function is irreversibly lost already at the time the disease manifests itself and thereafter continues to decline linearly with time.
- Trial name
- DIBASY (NCT00888836)
- Testing
- Bariatric surgery: Gastric bypass, Bariatric surgery: Bilio-pancreatic diversion, anti-diabetic drugs and behavioral suggestions
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Catholic University of the Sacred Heart
Obesity
Adipose Secretory Function in Patients Before & After Laparoscopic Surgery
The central hypothesis of our study is that metabolic and hemodynamic improvements following gastric bypass surgery are mediated by downregulation of inflammation-related adipokines produced by the intra-abdominal adipose tissue…
- Trial name
- NCT00495599
- Testing
- Cytokines assessed from fat tissue
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Type 2 Diabetes, Obesity
Changes in Glucose Metabolism After Roux-en-Y Gastric Bypass
Besides causing weight loss Roux-en-Y gastric bypass (RYGB) has profound effect on glucose metabolism leading to remission of type 2 diabetes early after surgery. However the mechanisms for this improvement remain uncertain.
- Trial name
- NCT01993511
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Dumping Syndrome
Impact of an Educational Personalized Clinical Support Device Preventive and a Referent Nurse in Surgery for Obesity
The postprandial dumping syndrome is a frequent consequence of Roux-en-Y Gastric ByPass due to the rapid emptying of the stomach remnant in to the intestinal lumen.
- Trial name
- IRCO (NCT02891330)
- Testing
- Dietary and nutritional recommendations conducted by a nurse
- Where
- 4 sites in France
- Volunteers
- 135 people
- Sponsor
- University Hospital, Lille
Obese Patients, Type 2 Diabetes Mellitus
Impact of Gastric Bypass Surgery on Risk of CVD in Type 2 Diabetes Mellitus
Central hypothesis is: Gastric bypass surgery reduces the risk of CVD in morbidly obese subjects (defined as BMI ≥35 kg/m2) with T2DM.
- Trial name
- NCT00444392
- Testing
- Calorie controlled diabetic diet for the control patients
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Vanderbilt University
Gastric Cancer, Gastrostomy
Stapler Reinforcement Patches Compared to Standard Staplers in Gastrojejunostomy
This is a multi-center, prospective, randomized controlled study aimed at compareing the impact of stapler reinforcement patches versus standard staplers on postoperative complications in gastrojejunostomy.
- Conditions
- Gastric Cancer, Gastrostomy, Anastomotic Leakage, Postoperative Complications
- Trial name
- NCT06464978
- Testing
- Stapler Reinforcement Patch, Standard Stapler
- Where
- China
- Volunteers
- 382 people
- Sponsor
- Nanchong Central Hospital
Morbid Obesity, Insulin Resistance
Assessment of Insulin Resistance, NAFLD, Predictors of CV Morbidity, and Subcutaneous Adipose and Visceral Adipose Gene Expression in Patients Undergoing Gastric Bypass Surgery
The purpose of this research is to further study the effect weight loss after gastric bypass surgery has on the heart and blood pressure and on how the body uses or metabolizes the sugars, fats and proteins we eat.
- Conditions
- Morbid Obesity, Insulin Resistance, Non-Alcoholic Fatty Liver Disease
- Trial name
- NCT01007955
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Massachusetts, Worcester
Gastric Bypass Surgery, Gastric Banding
Mechanisms of Diabetes Control After Weight Loss Surgery, Sub-study #1
Gastric bypass (GBP) and laparoscopic adjustable banding (AGB) are common procedures that can result in significant weight loss and significantly improve type 2 diabetes in 40-80% of cases.
- Conditions
- Gastric Bypass Surgery, Gastric Banding, Type 2 Diabetes
- Trial name
- NCT01930448
- Where
- United States
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Bariatric Surgery, Micronutrient Deficiencies
Supplementation After Bariatric Surgery
The aim of this study is to assess medication adherence to vitamin and mineral supplements after bariatric surgery and identify factors that may influence adherence.
- Conditions
- Bariatric Surgery, Micronutrient Deficiencies, Obesity
- Trial name
- NCT04412421
- Testing
- Gastric Bypass, Sleeve Gastrectomy
- Where
- Sweden
- Volunteers
- 260 people
- Sponsor
- Region Östergötland
Bariatric Surgery Candidate
Pharmacokinetics and Pharmacodynamics of Edoxaban Before and After Bariatric Surgery
The study will be conducted at a single site in the Canada, Quebec. Participants will be recruited from the bariatric surgery clinic and will be required to be either, waiting for sleeve gastrectomy surgery (n=12, restrictive…
- Trial name
- EXPOSE (NCT06326138)
- Testing
- Edoxaban Pharmacokinetics and Pharmacodynamics
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Obesity, Morbid Obesity
DIT After RYGB - A Prospective Study
Bariatric surgery is the only satisfactory treatment for loss and weight maintenance in obese patients. This loss is a result of several factors that go beyond the simple anatomical abnormality of the gastrointestinal tract and…
- Conditions
- Obesity, Morbid Obesity, Bariatric Surgery
- Trial name
- DIT RYGB (NCT01759667)
- Testing
- A standard mixed Meal
- Where
- Brazil
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Silvia Leite Faria
Incretin Hormones Plasma Levels, Gastric Bypass Surgery
A Comparative Study Between Effect Of Mini-gastric Bypass and Single Anastmosis Sleeve Jujenal Bypass On Levels Of GLP-1, GIP, PYY, Insulin Resistance and Type II DM Resolution
The aim of this work is to compare the outcome of Single Anastomosis Sleeve Jejunal Bypass (SASJ) with One Anastomosis Gastric Bypass (OAGB) as regards effect on levels of GLP-1 mainly, PYY and GIP and subsequent effect on…
- Trial name
- NCT07475143
- Testing
- Single anastomosis sleeve jejunal bypass, One anastomosis gastric bypass
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Surgery, Bariatric Surgery Candidate
Magnetic System in Bariatric and General Surgery
Magnetic devices have been successfully used in bariatric surgery. To the date the only reported use of the magnet was for liver retraction.
- Trial name
- NCT04944810
- Testing
- Magnetic Gastric Bypass, Magnetic Sleeve Gastrectomy, Revisional Bariatric Surgery
- Where
- Venezuela
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Unidad Internacional de Cirugia Bariatrica y Metabolica