Clinical trials: Gastric Cancer, completed
Gastric Cancer
D2 Versus D1 Gastrectomy of Operable Gastric Cancer
Surgery is the mainstay treatment of operable gastric carcinoma but the optimal extent of lymph node (LN) dissection is controversial.
- Trial name
- NCT04429841
- Testing
- Radical gastrectomy with D1 lymphadenectomy, Radical gastrectomy with D2 lymphadenectomy
- Where
- Egypt
- Volunteers
- 148 people
- Sponsor
- Alexandria University
Gastric Subepithelial Tumors
Endoscopic Ultrasound-guided Needle-based Confocal Laser Endomicroscopy for Diagnosis of Gastric Subepithelial Tumors
The differential diagnosis of gastric subepithelial tumors by endoscopic ultrasound is currently suboptimal. Needle-based confocal laser endomicroscopy (nCLE) is a novel endoscopic technique, which is compatible with the 19-gauge…
- Trial name
- NCT02936986
- Where
- China
- Volunteers
- 94 people
- Sponsor
- Shandong University
Locally Advanced Gastric Cancer
A Comparison of XELOX Regimen and EOX Regimen as Neoadjuvant Chemotherapy Regimen for Locally Advanced Gastric Cancer.
This study is designed to assess what is the better neoadjuvant chemotherapy regimen for patients with initially unresectable locally advanced gastric cancer.
- Trial name
- NCT02192983
- Where
- China
- Volunteers
- 242 people
- Sponsor
- Tianshu Liu
Pancreatic Head Neoplasm, Delayed Gastric Emptying
Nasogastric Decompression Following Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD) remains the gold-standard operation for peri-ampullary neoplasms. Traditionally, gastric decompression via nasogastric intubation has been employed postoperatively to prevent nausea, vomiting…
- Conditions
- Pancreatic Head Neoplasm, Delayed Gastric Emptying, Post Operative Ileus, Whipple Procedure
- Trial name
- whipple (NCT06413888)
- Testing
- pancreaticoduodenectomy
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Baylor College of Medicine
Gastric Cancer
A Study of Bevacizumab (Avastin) Versus Placebo in Combination With Capecitabine (Xeloda) and Cisplatin as First-Line Therapy for Advanced Gastric Cancer
This 2 arm study will compare the efficacy and safety of bevacizumab in combination with capecitabine and cisplatin versus placebo in combination with capecitabine and cisplatin in participants who have not received prior…
- Trial name
- AVATAR (NCT00887822)
- Testing
- Bevacizumab, Capecitabine, Cisplatin
- Where
- 14 sites in China
- Volunteers
- 202 people
- Sponsor
- Hoffmann-La Roche
Gastric Cancer
Gastric Partitioning Procedure for the Treatment of Unresectable and Obstructive Distal Gastric Cancer
The incidence of unresectable and obstructive gastric cancer patients ranges in the literature from 5 to 30 % . In such cases, gastro-entero anastomosis is traditionally performed and can improve the quality of life by relieving…
- Trial name
- NCT02064803
- Testing
- Gastro-entero anastomosis only, Gastric partitioning Plus Gastro-entero anastomosis
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Stomach Cancer, Chemotherapy-induced Nausea and Vomiting
The Effect of Stress Ball on Nausea, Anxiety, and Fatigue in Patients With Stomach Cancer
In this study, we will observe the effects of the Stress Ball.
- Conditions
- Stomach Cancer, Chemotherapy-induced Nausea and Vomiting, Fatigue
- Trial name
- NCT07540169
- Testing
- A device/tool called a stress ball
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Yuzuncu Yil University
Helicobacter Infections
Helicobacter Pylori and Proton Pump Inhibitor
The purpose of this study is to know the distribution of HP in stomach before use of PPI, during use of PPI, and after stop of PPI.
- Trial name
- NCT02449941
- Testing
- PPI (proton pump inhibitor)
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Gastric Adenocarcinoma, Metastatic Gastric Cancer
Personalized Targeted IMMUNOtherapy-based Regimens in Recurrent GASTric Adenocarcinoma (IMMUNOGAST)
For patients with advanced/metastatic gastric adenocarcinomas in progression after a first line chemotherapy comprising platinum and fluoropyrimidine, the reported second line treatments are : 1) paclitaxel combined with…
- Conditions
- Gastric Adenocarcinoma, Metastatic Gastric Cancer, Metastatic Adenocarcinoma, Advanced Gastric Carcinoma
- Trial name
- IMMUNOGAST (NCT04739202)
- Testing
- Atezolizumab + Ipatasertib, Atezolizumab + Bevacizumab
- Where
- 8 sites in France
- Volunteers
- 54 people
- Sponsor
- Hospices Civils de Lyon
Chronic Myeloid Leukemia, Chronic Phase
Pharmacokinetics Profiles of HQP1351 Under Fasting and High-fat Meals in Patients With Chronic Myeloid Leukemia
The purpose of this study is to characterize the pharmacokinetics of HQP1351 in participants with resistant chronic myeloid leukemia (CML) in chronic phase (CP) after high-fat and fasting meals separately（Selection of high-fat…
- Trial name
- CML (NCT03882281)
- Testing
- HQP1351
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Ascentage Pharma Group Inc.
Early Gastric Adenocarcinoma, Adenocarcinoma, Tubular
Effects of Oral Rabeprazole on the Prevention of Ulcer Bleeding Following Endoscopic Mucosal Resection
The purpose of this study is: To examine if oral administration of Pariet (proton pump inhibitor, 20mg tablets, twice daily for 5 days) before Endoscopic mucosal resection(EMR) exhibits preventive effects of ulcer bleeding…
- Trial name
- NCT00844675
- Testing
- rabeprazole
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- The Catholic University of Korea
Gastric Cancer, Gastroesophageal Junction Cancer
A Study of Treatment Patterns in HER2-positive Unresectable and Advanced Gastric/ Gastroesophageal Junction Cancer in China
This study will be conducted to retrospectively evaluate the treatment patterns in first-line, second-line, and subsequent lines of therapy for HER2-positive Gastric Cancer/Gastroesophageal Junction Cancer (GC/GEJC) patients.
- Trial name
- REHEARSAL (NCT06585501)
- Testing
- No drug
- Where
- 9 sites in China
- Volunteers
- 805 people
- Sponsor
- Daiichi Sankyo
Gastrointestinal Cancer
Effectiveness of Low Dose Aspirin in Decreasing the Chance Getting Stomach and Intestine Cancer
In this study, researchers wanted to learn more about the effect of Aspirin taken as low dose (75 - 300 mg) in preventing stomach, colorectal and esophagus cancer.
- Trial name
- ENgAGE-HK (NCT04081831)
- Testing
- Acetylsalicylic Acid (Aspirin, BAYE4465)
- Where
- Hong Kong
- Volunteers
- 99,999 people
- Sponsor
- Bayer
Stomach Neoplasms, Esophageal Neoplasms
A Study of BMS-833923 With Cisplatin and Capecitabine in Inoperable, Metastatic Gastric, Gastroesophageal, or Esophageal Adenocarcinomas
The purpose of this study is to determine the maximum tolerated dose (MTD) of BMS-833923 administered in combination with Cisplatin and Capecitabine as first-line therapy in subjects with inoperable metastatic gastric…
- Trial name
- NCT00909402
- Testing
- BMS-833923, Cisplatin, Capecitabine
- Where
- 6 sites in United States, Canada and 2 more
- Volunteers
- 39 people
- Sponsor
- Bristol-Myers Squibb
Gastro Intestinal Stromal Tumour
Multicentre Placebo-controlled Double-blinded Phase II Study of Lenvatinib Efficacy in Patients With Locally Advanced or Metastatic GIST (Gastrointestinal Stromal Tumor) After Imatinib/Sunitinib Failure
The primary objective is to compare the efficacy of lenvatinib plus Best Supportive Care versus Placebo plus Best Supportive Care in the treatment of patients with advanced GIST, after failure of imatinib and sunitinib.
- Trial name
- LENVAGIST (NCT04193553)
- Testing
- Lenvatinib, Best supportive care
- Where
- 14 sites in France
- Volunteers
- 77 people
- Sponsor
- Centre Leon Berard
Subtotal Gastrectomy, Stomach Cancer
Effect of Erythromycin Before Endoscopy of Patients With Subtotal Gastrectomy (STG), High Risk of Gastric Stasis
Erythromycin has a prokinetic effect through Motilin receptor. It evokes migrating motor complex with longer and stronger contraction.
- Trial name
- NCT01659619
- Testing
- Erythromycin
- Where
- South Korea
- Volunteers
- 114 people
- Sponsor
- The Catholic University of Korea
Gastric Cancer
Laparoscopic Versus Open Gastrectomy for Gastric Cancer
This is the first randomized controlled trial comparing laparoscopic and open gastrectomy for resectable gastric cancer in a Western population.
- Trial name
- LOGICA (NCT02248519)
- Testing
- Open Gastrectomy, Laparoscopic Gastrectomy
- Where
- 10 sites in Netherlands
- Volunteers
- 210 people
- Sponsor
- UMC Utrecht
Gastric Intestinal Metaplasia, Gastric Cancer
RCT: WLE vs. NBI in Upper Gastrointestinal Endoscopy
It is recognized that gastroscopy can miss intestinal metaplasia, dysplasia and early gastric cancer. This could conceivably be due to the fact that these lesions may only present as subtle mucosal changes on conventional white…
- Trial name
- NCT01945177
- Testing
- narrow band imaging, white light endoscopy
- Where
- Singapore
- Volunteers
- 600 people
- Sponsor
- Changi General Hospital
Gastric Cancer
Open-label, Dose-finding Study to Determine Antibody Response to G17DT Treatment in Patients With Gastric Cancer.
An open label, dose-finding, schedule-changing, sequential, multiple dose, multi-center study in patients with Stage I-III gastric cancer. The first group of patients received a starting dose of 250 µg at weeks 0, 1, and 3.
- Trial name
- GC3 (NCT02233712)
- Testing
- G17DT
- Volunteers
- 33 people
- Sponsor
- Cancer Advances Inc.
Gastric Cancer, Pancreatic Cancer
A Collection of Clinical and Epidemiologic Data Combined With Tissue and Blood From Patients With a Diagnosis of Neuroendocrine Tumors
The purpose of this study is to establish a neuroendocrine tumor registry. A registry is a collection of information. To create this registry, the investigators would like to get information, blood and tumor samples from people…
- Trial name
- NCT00745381
- Testing
- questionnaire, Blood specimens
- Where
- 3 sites in United States
- Volunteers
- 238 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
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