Clinical trials: Gastric Cancer, completed
Advanced Gastric Cancer
Safety and Efficacy of RAD001 (Everolimus) Monotherapy Plus Best Supportive Care in Patients With Advanced Gastric Cancer (AGC)
This study is designed to assess the safety and efficacy of RAD001 monotherapy in patients with advanced gastric cancer which has progressed after one or two lines of prior chemotherapy.
- Trial name
- GRANITE-1 (NCT00879333)
- Testing
- Everolimus, Best Supportive Care (BSC)
- Where
- 122 sites in United States, Argentina and 20 more
- Volunteers
- 656 people
- Sponsor
- Novartis Pharmaceuticals
Neoplasms, Advanced Solid
A Study to Assess the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics (PK) of TAK-931 in Participants With Advanced Solid Tumors
The purpose of this study is to estimate the relative bioavailability of TAK-931 tablets in reference to powder-in capsule (PIC) and to assess the effect of food and esomeprazole on the pharmacokinetics (PK) of TAK-931 as a…
- Trial name
- NCT03708211
- Testing
- TAK-931 PIC, TAK-931 Tablet, Esomeprazole
- Where
- 4 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
Stage I Adult Liver Cancer, Stage I Colorectal Cancer
Electronic Monitoring Device of Patient-Reported Outcomes and Function in Improving Patient-Centered Care in Patients With Gastrointestinal Cancer Undergoing Surgery
This pilot clinical trial studies an electronic monitoring device of patient-reported outcomes (PROs) and function in improving patient-centered care in patients with gastrointestinal cancer undergoing surgery.
- Conditions
- Stage I Adult Liver Cancer, Stage I Colorectal Cancer, Stage IA Gastric Cancer, Stage IA Pancreatic Cancer
- Trial name
- NCT02511821
- Testing
- Computer-Assisted Intervention, Vivofit watch, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- City of Hope Medical Center
Anemia, Breast Cancer
Assessment of Quality of Life in Patients With Symptomatic Chemotherapy-induced Anaemia
This is a multicenter, international, prospective, observational study of patients who are receiving systemic chemotherapy for solid tumour cancers (breast, colorectal, ovarian, prostate, lung, bladder, endometrial, renal…
- Conditions
- Anemia, Breast Cancer, Cancer, Colorectal Cancer
- Trial name
- NCT01444456
- Where
- 117 sites in Austria, Belgium and 7 more
- Volunteers
- 1,262 people
- Sponsor
- Amgen
Stomach Neoplasms, Neoadjuvant Therapy
A Randomized Phase II Trial of Neoadjuvant Chemotherapy Compared With Chemoradiotherapy in Gastric Adenocarcinoma
This prospective, randomized phase II study is designed to evaluate weather neoadjuvant chemoradiotherapy is superior to neoadjuvant chemotherapy with both followed by surgery and postoperative chemotherapy for locally advanced…
- Conditions
- Stomach Neoplasms, Neoadjuvant Therapy, Chemoradiotherapy, Chemotherapy
- Trial name
- NCT02301481
- Testing
- SIB-IMRT, S-1, Surgery
- Where
- China
- Volunteers
- 71 people
- Sponsor
- Chinese Academy of Medical Sciences
Gastric Cancer
Effect of Helicobacter Pylori Eradication After Subtotal Gastrectomy on Survival Rate of Gastric Cancer Patients: Retrospective Study
In this study, we will observe the long-term survival rate, overall mortality rate, gastric cancer specific mortality rate, and the incidence rate of metachronous cancer in patients who received subtotal gastrectomy, with or…
- Trial name
- NCT03978481
- Testing
- Helicobacter pylori eradication (combination therapy)
- Where
- South Korea
- Volunteers
- 3,700 people
- Sponsor
- Seoul National University Bundang Hospital
Stomach Cancer, Gastric Cancer
Discovery and Validation of Plasma DNA Methylation Biomarker for Detection of Stomach Cancer
Background: Stomach cancer is common around the world. The US is a low-risk region. But the 5-year survival rate in the US is low. This is because the cancer is usually in a late stage by the time it is diagnosed.
- Trial name
- NCT03076567
- Where
- United States
- Volunteers
- 440 people
- Sponsor
- National Cancer Institute (NCI)
Hypoxia, Gastric Cancer
Nasal Mask Kit in Gastrointestinal Endoscopy
Hypoxia is the most common adverse event in gastrointestinal endoscopes sedated with propofol. The nasal mask oxygen kit has good sealing to ensure an adequate oxygen supply and is convenient and economical.The aim of this…
- Conditions
- Hypoxia, Gastric Cancer, Gastric Polyp, Colon Polyp
- Trial name
- NASO (NCT05405530)
- Testing
- nasal mask oxygen kit, regular nasal cannula
- Where
- 3 sites in China
- Volunteers
- 1,204 people
- Sponsor
- RenJi Hospital
Gastrointestinal Neoplasms, Gastric Cancer
A Phase I Study of S-1 in Combination With Radiotherapy in Locally Advanced or Recurrent Gastric Cancer
The purpose of this study is to determine maximum tolerated dose (MTD), dose limiting toxicities (DLT) and recommend a proper dose for our phase II study of S-1 when combined with radiation therapy for locally advanced or…
- Trial name
- NCT01291407
- Testing
- S-1
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Chinese Academy of Medical Sciences
Stage T3-4NxM0 Gastric Cancer
Neo-adjuvant Chemotherapy in Locally Advanced Gastric Cancer
Thymidylate Synthase (TS) is a key enzyme in the synthesis of DNA and the target enzyme inhibited by 5-fluorouracil (5-FU). TS level in the tumour cells has been reported as predictive to response to 5-FU and a prognostic factor…
- Trial name
- NCT00414271
- Testing
- Docetaxel, Capecitabine
- Where
- Singapore
- Volunteers
- 18 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Breast Cancer, Ovarian Cancer
A Study to Evaluate the Effects of Veliparib on Heart Rhythms in Patients With Solid Tumors
This is a randomized Phase 1 study to evaluate the effects of Veliparib on cardiac repolarization in patients with solid tumors who's cancer has recurred or is no longer responding to current treatment.
- Conditions
- Breast Cancer, Ovarian Cancer, Colon Cancer, Lung Cancer
- Trial name
- NCT02009631
- Testing
- Veliparib (ABT-888)
- Where
- 5 sites in United States, Netherlands and 1 more
- Volunteers
- 45 people
- Sponsor
- AbbVie
Adenocarcinoma of Stomach or Esophagogastric Junction
Efficacy of Cetuximab in Combination With Irinotecan and 5- FU/FA in Treatment of Metastatic Gastric Cancer
Based on the current promising results with irinotecan and cetuximab in patients with recurrent metastatic colorectal cancer, and the excellent results of Irinotecan and 5-FU in gastric cancer , the present clinical study to…
- Trial name
- GC-CIF-2005 (NCT01123811)
- Testing
- Cetuximab IF
- Where
- 10 sites in Germany
- Volunteers
- 45 people
- Sponsor
- Johannes Gutenberg University Mainz
Cervical Cancer, Microsatellite Instability (MSI)-High Endometrial Cancer
A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies
The purpose of this study is to determine the safety, tolerability, and preliminary efficacy of INCAGN02385 in participants with advanced malignancies.
- Conditions
- Cervical Cancer, Microsatellite Instability (MSI)-High Endometrial Cancer, Gastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ]), Esophageal Cancer
- Trial name
- NCT03538028
- Testing
- INCAGN02385
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- Incyte Biosciences International Sàrl
Gastric Cancer (GC), Malnutitrion
Combined Oral and Parenteral Nutritional Therapy After Gastrectomy for Gastric Cancer
Patients undergoing gastrectomy for gastric cancer frequently experience insufficient oral intake during the postoperative recovery period because of reduced gastric capacity, early satiety, and gastrointestinal symptoms.
- Trial name
- BRIDGE-GC (NCT07604857)
- Testing
- Oral Nutritional Supplementation, Parenteral Nutrition, Standard Postoperative Nutritional Care
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Kyo Young Song
Adenocarcinoma of the Gastroesophageal Junction, Diffuse Adenocarcinoma of the Stomach
Irinotecan Hydrochloride With or Without Alvocidib in Treating Patients With Advanced Stomach or Gastroesophageal Junction Cancer That Cannot Be Removed By Surgery
This randomized phase II trial studies how well giving irinotecan hydrochloride with or without alvocidib works in treating patients with advanced stomach or gastroesophageal junction cancer that cannot be removed by surgery.
- Conditions
- Adenocarcinoma of the Gastroesophageal Junction, Diffuse Adenocarcinoma of the Stomach, Intestinal Adenocarcinoma of the Stomach, Mixed Adenocarcinoma of the Stomach
- Trial name
- NCT00991952
- Testing
- alvocidib, irinotecan hydrochloride, laboratory biomarker analysis
- Where
- 5 sites in United States
- Volunteers
- 19 people
- Sponsor
- National Cancer Institute (NCI)
Gastric Cancer by AJCC V8 Stage, Resectable Carcinoma
Perioperative Treatment in Resectable Gastric Cancer With Spartalizumab (PDR001) in Combination With Fluorouracil, Leucovorin, Oxaliplatin, and Docetaxel (FLOT)
Multicenter, open-label, non randomized, phase 2 trial in resectable gastric or gastroesophageal junction adenocarcinoma: Perioperative Treatment by Spartalizumab (PDR001) in Combination with fluorouracil, leucovorin…
- Trial name
- GASPAR (NCT04736485)
- Testing
- perioperative treatment
- Where
- 13 sites in France
- Volunteers
- 67 people
- Sponsor
- Centre Francois Baclesse
Locally Advanced Malignant Neoplasm, Gastric Cancer
Adjuvant Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Gastric Cancer
The purpose of this study is to determine safety and feasibility of adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) with mitomycin and cisplatin in patients with locally advanced gastric cancer undergoing standard…
- Trial name
- NCT02672865
- Testing
- Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Loma Linda University
Stomach Neoplasms
Influence of Positive Margins on Tumour Recurrence and Overall Survival After Gastrectomy for Gastric Cancer
Incidence of positive surgical margins after curative gastrectomy ranges from 1% to 20%. It has been suggested that positive surgical margins is an adverse prognosis factor, with a higher local recurrence and worse overall…
- Trial name
- NCT04439812
- Testing
- Observation
- Volunteers
- 267 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Gastric Cancer With Positive Peritoneal Exfoliative Cytology
Diagnosis of Peritoneal Exfoliative Cytology-positive Gastric Cancer Based on Artificial Intelligence-driven Virtual Biopsy Technology
This clinical study aims to develop and evaluate an artificial intelligence (AI)-driven virtual biopsy technology for the diagnosis of gastric cancer with positive peritoneal exfoliative cytology (PEC).
- Trial name
- GC-CY1 (NCT06759467)
- Testing
- AI-Driven Virtual Biopsy for Diagnosis of Peritoneal Exfoliative Cytology-Positive Gastric Cance
- Where
- China
- Volunteers
- 346 people
- Sponsor
- Qun Zhao
Esophageal Cancer, Gastric Cancer
The Effect of Nutritional Counseling for Cancer Patients
Background and aims: Cancer-related malnutrition is multifactorial and related to a bad prognosis. The aim of this study was to investigate the effect of intensive, individual dietary counseling of patients in radiotherapy and/or…
- Conditions
- Esophageal Cancer, Gastric Cancer, Uterine Cancer
- Trial name
- NCT01962272
- Testing
- Weekly nutritional counseling, Forticare®.
- Where
- Denmark
- Volunteers
- 61 people
- Sponsor
- University of Copenhagen
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